3x2 Achievement Goals, Friendship and Affectivity in Physical Education: Age-Gender Differences

Se persiguen tres objetivos: (a) analizar las diferencias relativas a la edad y sexo en las metas de logro 3x2, metas de amistad, y afectividad en Educación Física, (b) estudiar las relaciones entre esas variables, y (c) explorar el valor predictivo de las metas de logro 3x2 y amistad sobre la afectividad. La muestra estuvo formada por 1610 alumnos (855 varones y 755 mujeres) de 10 a 17 años. Se realizaron MANOVAS, análisis univariados (Scheffé), y regresiones lineales. Los resultados mostraron un descenso significativo de las metas de logro (excepto aproximación-otro), metas de amistad y afecto positivo debido al desarrollo. Los varones puntuaron más alto las metas de aproximación-tarea, aproximación-otro, y evitación-otro. Las metas de aproximación-tarea y aproximación-amistad fueron los principales predictores positivos del afecto positivo. La franja de 13 a 14 años muestra una gran sensibilidad a los tres estándares de competencia de logro, competencia social e inestabilidad afectivaThe objectives of the study are three: (a) to analyze the differences related to age and sex in the 3x2 achievement goals, the friendship goals, and the affectivity in Physical Education, (b) to study the relationships between these variables, and c) to explore the predictive value of the 3x2 achievement goals and friendship on affectivity. The sample consisted of 1610 students (855 males and 755 females), aged between 10 and 17 years. MANOVAS, univariate analyzes (Scheffé), and linear regressions were performed. The results showed a significant decrease in achievement goals (except other-approach), friendship goals, and positive affect due to development. Males scored higher on task-approach, other-approach, and other-avoidance goals than women. Task-approach and friendship-approach were the main positive predictors of positive affect. The range of 13 to 14 years shows a great sensitivity to the three competences of achievement, social competence, and affective instabilit

Two-Dimensional Time-Domain Antenna Arrays for Optimum Steerable Energy Pattern with Low Side Lobes

This document presents the synthesis of different two-dimensional time-domain antenna arrays for steerable energy patterns with side lobe levels. The research is focused on the uniform and nonuniform distributions of true-time exciting delays and positions of antenna elements. The uniform square array, random array, uniform concentric ring array, and rotated nonuniform concentric ring array geometries are particularly studied. These geometries are synthesized by using the well-known sequential quadratic programming. The synthesis regards the optimal true-time exciting delays and optimal positions of pulsed antenna elements. The results show the capabilities of the different antenna arrays to steer the beam in their energy pattern in time domain and how their performance is in frequency domain after the synthesis in time domain

Textos Médico-Farmacéuticos renacentistas en la Biblioteca Pública de Orihuela

En la Biblioteca Pública de la ciudad de Orihuela, situada en los márgenes del río Segura, habiendo desempeñado un papel importante a lo largo de la historia, se conserva una amplia colección de libros médico-farmacéuticos, provenientes de la Universidad Literaria que allí existió en el siglo XVI. Del fondo de libros antiguos, nosotros recogemos en este trabajo todos los pertenecientes al siglo XVI que por su carácter médico-farmacéutico tienen un especial interés para los historiadores de la Medicina y de la Farmacia

Intra-individual effects of food upon the pharmacokinetics of rifampicin and isoniazid

Background: Poor response to TB therapy might be attributable to subtherapeutic levels in drug-compliant patients. Pharmacokinetic parameters can be affected by comorbidities or the interaction of drugs with food. Objectives: This study aimed to determine the effect of food intake upon pharmacokinetics of rifampicin and isoniazid in a Peruvian population with TB. Methods: Rifampicin and isoniazid levels were analysed at 2, 4 and 6 h after drug intake in both fasting and non-fasting states using LC-MS methods. Results: Sixty patients participated in the study. The median rifampicin Cmax and AUC0–6 were higher during fasting than non-fasting: 7.02 versus 6.59 mg/L (P = 0.054) and 28.64 versus 24.31 mg·h/L (P = 0.002). There was a statistically significant delay overall of non-fasting Tmax compared with the fasting state Tmax (P = 0.005). In the multivariate analysis, besides the effect of fasting, Cmax for females was 20% higher than for males (P = 0.03). Concerning isoniazid, there were significant differences in the Cmax during non-fasting (median = 3.51 mg/L) compared with fasting (4.54 mg/L). The isoniazid dose received had an effect upon the isoniazid levels (1.26, P = 0.038). In the multivariate analysis, isoniazid exposure during fasting was found to be 14% higher than during non-fasting (CI = 1.02–1.28, P < 0.001). Neither radiological extent of the disease nor consumption of food with drug intake nor pharmacokinetics of rifampicin or isoniazid was associated with a poorer treatment outcome. Conclusions: Rifampicin in particular and isoniazid pharmacokinetics were significantly affected by the intake of the drug with food between and within individuals

Psoriasis vulgaris: Relationship between oral and periodontal conditions and disease severity

Psoriasis is distributed across the world with a prevalence ranging from 0.5% to 4.6% [1, 2]. This condition has been associated with other diseases, or comorbidities, such as oral cavity involvement, including oral lesions and periodontal disease, thus reaffirming that this is a systemic disease [3, 4]. Psoriasis is a chronic, inflammatory disease which is characterized by the exaggerated proliferation of keratinocytes as a result of immune system activation through T lymphocytes in focal cutaneous areas [5, 6]. In most cases of psoriasis, oral lesions are associated with the presence of geographic and fissured tongue, although data show an increased frequency of associations with generalized pustular psoriasis [7]. It has been estimated that the actual prevalence of fissured tongue and geographic tongue is 6 - 33% and 1-18%, respectively, suggesting that these might represent different expressions of the same disease [7]. However, there is no consensus of the clinical description of what could be considered an oral psoriatic lesion, oral evaluation, or examination, is not a regular procedure in patients with psoriasis [7, 8]. Oral lesions are generally asymptomatic, although there might be tongue swelling and pain when deep fissures are formed [7, 8]. Furthermore, bad tongue hygiene can cause halitosis and tissue swelling due to the accumulation of food residues in fissures, thus causing burning and stinging, especially after contact. However, this association is debatable because it is not known if such oral manifestations are a symptom of disease severity or represent an expression of the disease itself [8]. On the other hand, periodontal disease is marked by an exaggerated response of the immune system to oral microbiota, making it a chronic inflammatory disease which is mediated immunologically, in which immune cells cause inflammation and cellular destruction [9]. Although the two pathologies are similar from the immunological aspect, some characteristics still render them separate diseases and there is no real association known between them [10, 11]. New research has shown that both psoriasis and periodontal disease have both experienced increased prevalence worldwide, and have been associated with other diseases and comorbidities, thus reconfirming that these are, indeed, systemic diseases [12, 13]. There are no existing reports in the published literature which describe the prevalence and frequency of psoriasis and periodontal disease in Colombia. We considered that it was very important for such clinical data to be available because we believe that appropriate examinations should be carried out on all patients with psoriasis, who may have multiple associated comorbidities. We also believe that such examinations should be performed on a regular basis. Furthermore, it is not yet known if the diagnosis of oral psoriasis should be made when lesions in the oral cavity present by themselves, or only at the same time as skin symptoms develop. Consequently, in this study, we aimed to investigate the association between periodontal diagnosis, microbiological components, the presence of IgG against Porphyromonas gingivalis (P. gingivalis), and the clinical manifestations of psoriasis