1,574 research outputs found
User Participation in Consulting Projects: Client and Provider Role Variations
This study presents a variation scheme of participation roles in consulting projects. Typical consulting assignments in the area known as IS planning involve strategic planning and information systems management, enterprise architecture, information management or information technology governance. Participation is a crucial issue in consulting on these issues. In the literature on participation, different roles and tasks have been found, but it is not always specified, on what types of projects or systems the results are based. The literature on consulting suggests some models for work division. In a two-phase qualitative study, we first collect possible tasks in ICT consulting projects, and then, based on further explorations, create a model for role variations in consulting. We compare roles suggested in the literature on participation and on consulting to our findings. The suggested variation model gives a common framework of reference for negotiations between the provider and the client, and helps to anticipate the needed competences and resources from both parties, and discern between their responsibilities
Multimodal optical characterisation of collagen photodegradation by femtosecond infrared laser ablation.
Collagen is a structural component of the human body, as a connective tissue it can become altered as a result of pathophysiological conditions. Although the collagen degradation mechanism is not fully understood, it plays an important role in ageing, disease progression and applications in therapeutic laser treatments. To fully understand the mechanism of collagen alteration, in our study photo-disruptive effects were induced in collagen I matrix by point-irradiation with a femtosecond Ti-sapphire laser under controlled laser ablation settings. This was followed by multi-modal imaging of the irradiated and surrounding areas to analyse the degradation mechanism. Our multi-modal methodology was based on second harmonic generation (SHG), scanning electron microscope (SEM), autofluorescence (AF) average intensities and the average fluorescence lifetime. This allowed us to quantitatively characterise the degraded area into four distinct zones: (1) depolymerised zone in the laser focal spot as indicated by the loss of SHG signal, (2) enhanced crosslinking zone in the inner boundary of the laser induced cavity as represented by the high fluorescence ring, (3) reduced crosslinking zone formed the outer boundary of the cavity as marked by the increased SHG signal and (4) native collagen. These identified distinct zones were in good agreement with the expected photochemical changes shown using Raman spectroscopy. In addition, imaging using polarisation-resolved SHG (p-SHG) revealed both a high degree of fibre re-orientation and a SHG change in tensor ratios around the irradiation spot. Our multi-modal optical imaging approach can provide a new methodology for defining distinct zones that can be used in a clinical setting to determine suitable thresholds for applying safe laser treatments without affecting the surrounding tissues. Furthermore this technique can be extended to address challenges observed in collagen based tissue engineering and used as a minimally invasive diagnostic tool to characterise diseased and non-diseased collagen rich tissues
Optimal Pacing for Running 400 m and 800 m Track Races
Physicists seeking to understand complex biological systems often find it
rewarding to create simple "toy models" that reproduce system behavior. Here a
toy model is used to understand a puzzling phenomenon from the sport of track
and field. Races are almost always won, and records set, in 400 m and 800 m
running events by people who run the first half of the race faster than the
second half, which is not true of shorter races, nor of longer. There is
general agreement that performance in the 400 m and 800 m is limited somehow by
the amount of anaerobic metabolism that can be tolerated in the working muscles
in the legs. A toy model of anaerobic metabolism is presented, from which an
optimal pacing strategy is analytically calculated via the Euler-Lagrange
equation. This optimal strategy is then modified to account for the fact that
the runner starts the race from rest; this modification is shown to result in
the best possible outcome by use of an elementary variational technique that
supplements what is found in undergraduate textbooks. The toy model reproduces
the pacing strategies of elite 400 m and 800 m runners better than existing
models do. The toy model also gives some insight into training strategies that
improve performance.Comment: 14 pages, 4 figures, submitted to the American Journal of Physic
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