2,003 research outputs found
A minor-merger origin for inner disks and rings in early-type galaxies
Nuclear disks and rings are frequent galaxy substructures, for a wide range
of morphological types (from S0 to Sc). We have investigated the possible
minor-merger origin of inner disks and rings in spiral galaxies through
collisionless N-body simulations. The models confirm that minor mergers can
drive the formation of thin, kinematically-cold structures in the center of
galaxies out of satellite material, without requiring the previous formation of
a bar. Satellite core particles tend to be deposited in circular orbits in the
central potential, due to the strong circularization experienced by the
satellite orbit through dynamical friction. The material of the satellite core
reaches the remnant center if satellites are dense or massive, building up a
thin inner disk; whereas it is fully disrupted before reaching the center in
the case of low-mass satellites, creating an inner ring instead.Comment: 2 pages, 2 figures, Proceedings of the conference "Hunting for the
Dark: The Hidden Side of Galaxy Formation", held in Malta, 19-23 Oct. 2009,
ed. V. Debattista and C. C. Popescu, AIP Conf. Ser., in pres
Evolution along the sequence of S0 Hubble types induced by dry minor mergers. II - Bulge-disk coupling in the photometric relations through merger-induced internal secular evolution
Galaxy mergers are considered as questionable mechanisms for the evolution of
lenticular galaxies (S0's), on the basis that even minor ones induce structural
changes that are difficult to reconcile with the strong bulge-disk coupling
observed in the photometric scaling relations of S0's. We check if the
evolution induced onto S0's by dry intermediate and minor mergers can reproduce
their photometric scaling relations, analysing the bulge-disk decompositions of
the merger simulations presented in Eliche-Moral et al. (2012). The mergers
induce an evolution in the photometric planes compatible with the data of S0's,
even in those ones indicating a strong bulge-disk coupling. The mergers drive
the formation of the observed photometric relation in some cases, whereas they
induce a slight dispersion compatible with data in others. Therefore, this
evolutionary mechanism tends to preserve these scaling relations. In those
photometric planes where the morphological types segregate, the mergers always
induce evolution towards the region populated by S0's. The structural coupling
of the bulge and the disk is preserved or reinforced because the mergers
trigger internal secular processes in the primary disk that induce significant
bulge growth, even although these models do not induce bars. Intermediate and
minor mergers can thus be considered as plausible mechanisms for the evolution
of S0's attending to their photometric scaling relations, as they can preserve
and even strengthen any pre-existing structural bulge-disk coupling, triggering
significant internal secular evolution (even in the absence of bars or
dissipational effects). This means that it may be difficult to isolate the
effects of pure internal secular evolution from those of the merger-driven one
in present-day early-type disks (abridged).Comment: Accepted for publication in Astronomy & Astrophysics, 13 pages, 8
figures. Definitive version after proofs. Added references and corrected
typo
XMM-Newton and Deep Optical Observations of the OTELO fields: the Groth-Westphal Strip
OTELO (OSIRIS Tunable Emission Line Object Survey) will be carried out with
the OSIRIS instrument at the 10 m GTC telescope at La Palma, and is aimed to be
the deepest and richest survey of emission line objects to date. The deep
narrow-band optical data from OSIRIS will be complemented by means of
additional observations that include: (i) an exploratory broad-band survey that
is already being carried out in the optical domain, (ii) FIR and sub-mm
observations to be carried with the Herschel space telescope and the GTM, and
(iii) deep X-Ray observations from XMM-Newton and Chandra.Here we present a
preliminary analysis of public EPIC data of one of the OTELO targets,the
Groth-Westphal strip, gathered from the XMM-Newton Science Archive (XSA). EPIC
images are combined with optical BVRI data from our broadband survey carried
out with the 4.2m WHT at La Palma. Distance-independent diagnostics (involving
X/O ratio, hardness ratios, B/T ratio) are tested.Comment: 2 pages, 2 figures, uses graphicx package. To appear in proceedings
of "The X-Ray Universe 2005", San Lorenzo del Escorial, Spain, September
26-30, 200
Acute febrile illness is associated with Rickettsia spp infection in dogs
BACKGROUND: Rickettsia conorii is transmitted by Rhipicephalus sanguineus ticks and causes Mediterranean Spotted Fever (MSF) in humans. Although dogs are considered the natural host of the vector, the clinical and epidemiological significance of R. conorii infection in dogs remains unclear. The aim of this prospective study was to investigate whether Rickettsia infection causes febrile illness in dogs living in areas endemic for human MSF. METHODS: Dogs from southern Italy with acute fever (n = 99) were compared with case–control dogs with normal body temperatures (n = 72). Serology and real-time PCR were performed for Rickettsia spp., Ehrlichia canis, Anaplasma phagocytophilum/A. platys and Leishmania infantum. Conventional PCR was performed for Babesia spp. and Hepatozoon spp. Acute and convalescent antibodies to R. conorii, E. canis and A. phagocytophilum were determined. RESULTS: The seroprevalence rates at first visit for R. conorii, E. canis, A. phagocytophilum and L. infantum were 44.8%, 48.5%, 37.8% and 17.6%, respectively. The seroconversion rates for R. conorii, E. canis and A. phagocytophilum were 20.7%, 14.3% and 8.8%, respectively. The molecular positive rates at first visit for Rickettsia spp., E. canis, A. phagocytophilum, A. platys, L. infantum, Babesia spp. and Hepatozoon spp. were 1.8%, 4.1%, 0%, 2.3%, 11.1%, 2.3% and 0.6%, respectively. Positive PCR for E. canis (7%), Rickettsia spp. (3%), Babesia spp. (4.0%) and Hepatozoon spp. (1.0%) were found only in febrile dogs. The DNA sequences obtained from Rickettsia and Babesia PCRs positive samples were 100% identical to the R. conorii and Babesia vogeli sequences in GenBank®, respectively. Febrile illness was statistically associated with acute and convalescent positive R. conorii antibodies, seroconversion to R. conorii, E. canis positive PCR, and positivity to any tick pathogen PCRs. Fourteen febrile dogs (31.8%) were diagnosed with Rickettsia spp. infection based on seroconversion and/or PCR while only six afebrile dogs (12.5%) seroconverted (P = 0.0248). The most common clinical findings of dogs with Rickettsia infection diagnosed by seroconversion and/or PCR were fever, myalgia, lameness, elevation of C-reactive protein, thrombocytopenia and hypoalbuminemia. CONCLUSIONS: This study demonstrates acute febrile illness associated with Rickettsia infection in dogs living in endemic areas of human MSF based on seroconversion alone or in combination with PCR
Inter-channel Granger Causality for Estimating EEG Phase Connectivity Patterns in Dyslexia
Methods like Electroencephalography (EEG) and magnetoencephalogram (MEG) record brain oscillations and provide an invaluable insight into healthy and pathological brain function. These signals are helpful to study and achieve an objective and early diagnosis of neural disorders as Developmental Dyslexia (DD). An atypical oscillatory sampling could cause the characteristic phonological difficulties of dyslexia at one or more temporal rates; in this sense, measuring the EEG signal can help to make an early diagnosis of DD. The LEEDUCA study conducted a series of EEG experiments on children listening to amplitude modulated (AM) noise with slow-rhythmic prosodic (0.5–1 Hz) to detect differences in perception of oscillatory ampling that could be associated with dyslexia. The evolution of each EEG channel has been studied in the frequency domain, obtaining the analytical phase using the Hilbert transform. Subsequently, the cause-effect relationships between channels in ach subject have been reflected thanks to Granger causality, obtaining matrices that reflect the interaction between the different parts of the brain. Hence, each subject was classified as belonging or not to the control group or the experimental group. For this purpose, two ensemble classification algorithms were compared, showing that both can reach acceptable classifying erformance in delta band with an accuracy up to 0.77, recall of 0.91 and AUC of 0.97 using Gradient Boosting classifier.Universidad de Málaga. Campus de Excelencia Internacional AndalucĂa Tech
Uniportal robotic-assisted thoracic surgery for mediastinal tumors
info:eu-repo/semantics/publishedVersio
Sex and gender disparities in patients with advanced gastroesophageal adenocarcinoma: data from the AGAMENON-SEOM registry
Gastroesophageal cancer; Gender; SexCáncer gastroesofágico; Género; SexoCà ncer gastroesofà gic; Gènere; SexeBackground
Recommendations for research articles include the use of the term sex when reporting biological factors and gender for identities or psychosocial or cultural factors. There is an increasing awareness of incorporating the effect of sex and gender on cancer outcomes. Thus, these types of analyses for advanced gastroesophageal adenocarcinoma are relevant.
Patients and methods
Patients with advanced gastroesophageal adenocarcinoma from the Spanish AGAMENON-SEOM registry treated with first-line combination chemotherapy were selected. Epidemiology, characteristics of the disease, treatment selection, and results were examined according to sex.
Results
This analysis included 3274 advanced gastroesophageal adenocarcinoma patients treated with combination chemotherapy between 2008 and 2021: 2313 (70.7%) men and 961 (29.3%) women. Tumors in females were more frequently HER2-negative (67.8% versus 60.8%; P < 0.0001), grade 3 (45.4% versus 36.8%; P < 0.001), diffuse (43.3% versus 26.5%; P < 0.0001), and signet ring cell histology (40.5 versus 23.9%; P < 0.0001). Peritoneal spread was more common in women (58.6% versus 38.9%; P < 0.0001), while liver burden was lower (58.9% versus 71.1%; P < 0.0001). There were no significant differences in treatment recommendation. Treatment doses, density, and duration were comparable between sexes. Women experienced more diarrhea (46% versus 37%; P < 0.0001), neutropenia (51% versus 43%; P < 0.0001), and anemia (62% versus 57%; P < 0.0001). After a median 59.6-month follow-up [95% confidence interval (CI) 54.5-70.8], there were no statistically significant differences between the sexes in progression-free survival [6.21 months (95% CI 5.8-6.5 months) versus 6.08 months (95% CI 5.8-6.3 months); log-rank test, χ2 = 0.1, 1 df, P = 0.8] or in overall survival [10.6 months (95% CI 9.8-11.1 months) versus 10.9 months (95% CI 10.4-11.4 months); log-rank test: χ2 = 0.6, 1 df, P = 0.5].
Conclusion
This sex analysis of patients with advanced gastroesophageal adenocarcinoma from the AGAMENON-SEOM registry receiving first-line polychemotherapy found no differences in survival. Although women had worse prognostic histopathology, metastatic disease pattern, and greater toxicity, treatment allocation and compliance were equivalent
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