A Generic Communications Module for Cooperative 3D Visualization and Modelling over the Internet: the Collaborative API

Cooperative three-dimensional visualization and modeling applications allow a distributed group of users to work together with a model they share. To implement this kind of applications the underlying communications system must provide reliable and ordered multicast of users interactions. Due to the high complexity that characterizes the models, network bandwidth requirements have limited their use to intranets or in a few cases to very high-speed Internet connections. In this paper we present a communications module that solves this problem. The library exposed, which is called Collaborative API, supports the creation of very efficient cooperative 3D visualization and modeling applications by optimizing the use of the network resources. The Collaborative API, implements a new communications architecture: the dynamic client/server. The communications module presented in this paper is illustrated by two examples of applications that use it to provide cooperative 3D visualization over the Internet

Role of Mo in catalysts based on noble metals in hydrodeoxygenation reactions

The use of bio-energy as a renewable alternative to fossil fuels is nowadays attracting more and more attention. The bio-fuel from biomass seems to be a potential energy substitute for fossil fuels since it is a renewable resource that could contribute to sustainable development and global environmental preservation and it appears to have significant economic potential1. The problem is its high oxygen content, which gives undesirable properties for combustion. To remove oxygen, catalytic hydrodeoxygenation (HDO) reactions are carried out. Monometallic Mo/Si, Pt/Si as well as bimetallic PtMo/Si catalysts were prepared and evaluated in the hydrodeoxygenation (HDO)reaction of dibenzofurane (DBF) as a model molecule in biomass derived bio-oil.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Efficacy of DNA amplification in tissue biopsy samples to improve the detection of invasive fungal disease

AbstractThe performance of a pan-fungal PCR-based technique was evaluated to assess the aetiology of invasive fungal diseases (IFDs). A total of 89 formalin-fixed paraffin-embedded biopsy samples from 84 patients with proven IFD were studied. Culture of tissue was performed in 68 (81%) patients. The sensitivities of the PCR-based technique and microbiological culture of tissues were 89% and 56%, respectively (p <0.01). According to PCR results, Aspergillus species accounted for 67%, Candida species for 13%, zygomycetes for 11%, and rare and emerging fungi for 9%. Aspergillus species were significantly associated with lung samples (79.6%, p <0.01), Mucorales were associated with skin/subcutaneous samples, and Candida species were associated with gastrointestinal samples. Regarding biopsy samples with Aspergillus species, Aspergillus fumigatus DNA was detected in 43 of 50 (86%), and Aspergillus flavus in six of 50 (12%). PCR was positive in 24 of 30 (80%) cases with negative culture. In nine of the 84 patients, the PCR technique failed to amplify the DNA. Six also had negative cultures, and in the remaining three cases culture was positive (Rhizopus microsporus, Rhizopus arrhizus, and Sakseneae vasiformis), suggesting that the PCR technique was not as effective in amplifying the DNA of some species of Zygomycetes. In five cases, there was no correlation between culture results and those obtained with DNA amplification, indicating the possibility of a mixed infection or the presence of colonizer/contaminant microorganisms. In summary, PCR-based techniques for DNA amplification should be implemented in histopathology and microbiology departments, as they appear to be complementary to conventional methods for IFD detection

MIVES: modelo integrado de valor para evaluaciones de sostenibilidad

La valoración y agregación cuantitativa de los distintos requisitos que constituyen los tres pilares básicos de la sostenibilidad es importante para poder comparar de forma objetiva la incidencia relativa de alternativas de materiales o procesos e introducir mejoras. La mayoría de estos requisitos tienen unidades de medida diferentes. Por ello, para valorar el grado de sostenibilidad, es importante basarse en metodologías multicriterio de valoración que permitan valorar y ponderar todos estos requisitos de diferente índole. La metodología multicriterio y programa informático aquí presentado, “MIVES1: Modelo integrado de valor para evaluaciones de sosteniblidad”, permite obtener un único índice de valor que mide el grado de sostenibilidad del material o proceso evaluado. En las primeras fases de la metodología MIVES se realiza un modelo de valoración. En éste, se establecen las condiciones de contorno y los límites del sistema, se estructuran todos los aspectos que serán estudiados, se decide qué funciones de valor se utilizarán para valorar cada uno de los aspectos y por último se determina la importancia de cada uno de ellos. En estas primeras fases es donde realmente se toma la decisión, es decir, se definen los aspectos que serán estudiados y la forma de valorarlos sin estar condicionado por las valoraciones de las alternativas. Posteriormente, se seleccionan y valoran las alternativas. Las aplicaciones de la metodología MIVES son numerosas. Cabe destacar el Anejo 13 de la Instruccuón del hormigón2, que sirve para medir el grado de sostenibilidad de las estructuras de hormigón. La metodología desarrollada representa un avance en términos de valoración, ya que se dota de objetividad y claridad en los procedimientos. A la vez, permite que cualquier persona pueda estudiar la sostenibilidad de otras alternativas a partir del modelo de valoración creado.Postprint (published version

Topological Color Codes and Two-Body Quantum Lattice Hamiltonians

Topological color codes are among the stabilizer codes with remarkable properties from quantum information perspective. In this paper we construct a four-valent lattice, the so called ruby lattice, governed by a 2-body Hamiltonian. In a particular regime of coupling constants, degenerate perturbation theory implies that the low energy spectrum of the model can be described by a many-body effective Hamiltonian, which encodes the color code as its ground state subspace. The gauge symmetry $\mathbf{Z}_{2}\times\mathbf{Z}_{2}$ of color code could already be realized by identifying three distinct plaquette operators on the lattice. Plaquettes are extended to closed strings or string-net structures. Non-contractible closed strings winding the space commute with Hamiltonian but not always with each other giving rise to exact topological degeneracy of the model. Connection to 2-colexes can be established at the non-perturbative level. The particular structure of the 2-body Hamiltonian provides a fruitful interpretation in terms of mapping to bosons coupled to effective spins. We show that high energy excitations of the model have fermionic statistics. They form three families of high energy excitations each of one color. Furthermore, we show that they belong to a particular family of topological charges. Also, we use Jordan-Wigner transformation in order to test the integrability of the model via introducing of Majorana fermions. The four-valent structure of the lattice prevents to reduce the fermionized Hamiltonian into a quadratic form due to interacting gauge fields. We also propose another construction for 2-body Hamiltonian based on the connection between color codes and cluster states. We discuss this latter approach along the construction based on the ruby lattice.Comment: 56 pages, 16 figures, published version

Dynamical properties of liquid Al near melting. An orbital-free molecular dynamics study

The static and dynamic structure of liquid Al is studied using the orbital free ab-initio molecular dynamics method. Two thermodynamic states along the coexistence line are considered, namely T = 943 K and 1323 K for which X-ray and neutron scattering data are available. A new kinetic energy functional, which fulfills a number of physically relevant conditions is employed, along with a local first principles pseudopotential. In addition to a comparison with experiment, we also compare our ab-initio results with those obtained from conventional molecular dynamics simulations using effective interionic pair potentials derived from second order pseudopotential perturbation theory.Comment: 15 pages, 12 figures, 2 tables, submitted to PR

Factors associated with the development of septic shock in patients with candidemia: A post hoc analysis from two prospective cohorts

Background: Almost one third of the patients with candidemia develop septic shock. The understanding why some patients do and others do not develop septic shock is very limited. The objective of this study was to identify variables associated with septic shock development in a large population of patients with candidemia. Methods: A post hoc analysis was performed on two prospective, multicenter cohort of patients with candidemia from 12 hospitals in Spain and Italy. All episodes occurring from September 2016 to February 2018 were analyzed to assess variables associated with septic shock development defined according to The Third International Consensus Definition for Sepsis and Septic Shock (Sepsis-3). Results: Of 317 candidemic patients, 99 (31.2%) presented septic shock attributable to candidemia. Multivariate logistic regression analysis identifies the following factors associated with septic shock development: age > 50 years (OR 2.57, 95% CI 1.03-6.41, p = 0.04), abdominal source of the infection (OR 2.18, 95% CI 1.04-4.55, p = 0.04), and admission to a general ward at the time of candidemia onset (OR 0.21, 95% CI, 0.12-0.44, p = 0.001). Septic shock development was independently associated with a greater risk of 30-day mortality (OR 2.14, 95% CI 1.08-4.24, p = 0.02). Conclusions: Age and abdominal source of the infection are the most important factors significantly associated with the development of septic shock in patients with candidemia. Our findings suggest that host factors and source of the infection may be more important for development of septic shock than intrinsic virulence factors of organisms