230 research outputs found

    Fairness of Financial Contribution in Iranian Health System: Trend Analysis of National Household Income and Expenditure, 2003-2010

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    BACKGROUND: Social systems are dealing with the challenge of achieving fairness in the distribution of financial burden and protecting the risk of financial loss. The purpose of this paper is to present a trend analysis for the indicators related to fairness in healthcare's financial burden in rural and urban population of Iran during the eight years period of 2003 to 2010. METHODS: We used the information gathered by statistical center of Iran through sampling processes for the household income and expenditures. The indicators of fairness in financial contribution of healthcare were calculated based on the WHO recommended methodology. The indices trend analysis of eight-year period for the rural, urban areas and the country level were computed. RESULTS: This study shows that in Iran the fairness of financial contribution index during the eight-year period has been decreased from 0.841 in 2003 to above 0.827 in 2010 and The percentage of people with catastrophic health expenditures has been increased from 2.3 to above 3.1. The ratio of total treatment costs to the household overall capacity to pay has been increased from 0.055 to 0.068 and from 0.072 to 0.0818 in urban and rural areas respectively. CONCLUSION: There is a decline in fairness of financial contribution index during the study period. While, a trend stability of the proportion of households who suffered catastrophic health expenditures was found

    Main determinants of catastrophic health expenditures: a Bayesian logit approach on Iranian household survey data (2010)

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    BACKGROUND: During recent decades, increase in both health care expenditures and improvement of the awareness as well as health expectations have created some problems with regard to finance healthcare expenditures so that the issue of health financing by households has been determined as a major challenge in health sector. According to the definition by the World Health Organization, catastrophic health expenditure is considered if financial contribution for health service is more than 40 of income remaining after subsistence needs have been met. OBJECTIVES: The purpose of our study was determination of Main factors on catastrophic health expenditures in Iranian households. PATIENTS & METHODS: In this study, using an econometrics Bayesian logit model, determinants of the appearance of catastrophic health expenditure based on household budget data collected in 2010 were evaluated. RESULTS: Among Iranian households, the following groups were more likely to encounter with unsustainable health expenditures: rural households, households with the numbers of the elderly more than 65 years, illiterate householders, unemployed householders, households with some unemployed persons, households in upper rank and households with larger equivalent household size were higher than the average of community could significantly predict catastrophic health expenditures. CONCLUSIONS: About 2.1 of households were faced with catastrophic health expenditures in 2010. Thus, the implemented policies could not make considerable and significant change in improving justice in financing in health systems

    Enhancing the mechanical properties and formability of low carbon steel with dual-phase microstructures

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    In the present study, a special heat treatment cycle (step quenching) was used to produce a dual-phase (DP) microstructure in low carbon steel. By producing this DP microstructure, the mechanical properties of the investigated steel such as yield stress, tensile strength, and Vickers hardness were increased 14, 55, and 38%, respectively. In order to investigate the effect of heat treatment on formability of the steel, Nakazima forming test was applied and subsequently finite element base modeling was used to predict the outcome on forming limit diagrams. The results show that the DP microstructure also has a positive effect on formability. The results of finite element simulations are in a good agreement with those obtained by the experimental test

    Nutritive value of wheat straw treated with Pleurotus fungi

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    Soaked and pasteurised wheat straw was inoculated with five species of Pleurotus fungi (coded P-21, P-30, P-41, P-60 and P-90), packed in polyethylene bags and incubated in a fermentation chamber for 21 days. The chemical composition, in vitro digestibility and in sacco degradability of the treated and untreated straw were estimated using a complete randomised design consisting of six treatments and four replicates. In a feeding trial, in vivo digestibility and voluntary intake were determined in bulls, using a 3x3 change over design. Dietary treatments were: 1) untreated wheat straw (UWS) as control; 2) fungal treated (P-41) wheat straw before mushroom formation (FTWS); 3) spent wheat straw (SPWS) after mushrooms were harvested. Apart from P-90, fungal treatment significantly (p<0.05) increased the crude protein (CP) and reduced the cell wall components of the straw. The in vitro dry mater and organic mater digestibility significantly (p<0.05) increased in the treated straw particularly with the treatments of P-41 and P-60. The in situ degradability and in vivo digestibility of DM and OM were significantly (p<0.05) increased in treated straws with the highest values observed for treatment P-41. The intake of DM, OM and digestible organic mater (DOM) were significantly (p<0.05) increased in cows fed FTWS

    Rheological properties of bitumen modified with a combination of FT paraffin wax (sasobit®) and other additives

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    Fischer–Tropsch paraffin Sasobit® is a popular Warm Mix Asphalt (WMA) modifier applied to improve physi­cal and rheological properties of bitumen. Although there are a number of studies investigating the effects of sasobit on bitumen properties, little has been carried out on evaluation of bitumen modified by sasobit along with other additives. In this study, sasobit modified bitumen is used as the base condition and four common modifiers namely anti-stripping agent, Crumb Rubber (CR), Styrene–Butadiene–Styrene (SBS) and Polyphosphoric Acid (PPA) are added separately to the FT – Wax modified bitumen to evaluate the compatibility of these additives with sasobit. Morphological, rheological and physical properties of modified binders are studied using Fourier Transform Infrared Spectroscopy (FT-IR), Scan­ning Electron Microscopy (SEM), Dynamic Mechanical Analysis (DMA), Bending Beam Rheometer (BBR) alongside with conventional tests. Results show that although anti-stripping agent reduce bitumen viscosity and mixing/compac­tion temperatures of asphalt mixtures, it has significantly increased the stiffness of sasobit modified bitumen at low temperatures. Among all, sasobit and crumb rubber combination exhibited the best performance, especially at low and intermediate temperatures

    Effect of fungal treated wheat straw on the diet of lactating cows

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    This study was conducted to investigate the effects of diets that contained different levels of fungal treated wheat straw on the intake, digestibility and performance of lactating cows. Eight primiparous Holstein cows, in late lactation ranging from 170±10 days in milk and yielding 14.3±1.3 kg/d of fat corrected milk (FCM) were allocated into four diets with 0, 10, 20 and 30% fungal (Pleurotus ostreatus coded P-41) treated wheat straw in a 4×4 Latin Square experiment. The daily intake of DM, OM, DOM, CP and TDN were not affected by substitution of alfalfa hay with fungal treated wheat straw. Inclusion of the treated straw at different levels in the diet did not affect the digestibility of nutrients, except for the ADF that was significantly (p0.05) different among the diets. All cows gained weight, but the inclusion of treated straw to the diet significantly (p<0.05) increased the body weight gain and the highest amount was obtained in the diet containing 20% treated. Inclusion of fungal treated wheat straw up to 30% of the diet of lactating cows supplemented with a protein source such as cottonseed meal had not affected the nutrients intake and lactation performance

    Selection at a single locus leads to widespread expansion of toxoplasma gondii lineages that are virulent in mice

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    The determinants of virulence are rarely defined for eukaryotic parasites such as T. gondii, a widespread parasite of mammals that also infects humans, sometimes with serious consequences. Recent laboratory studies have established that variation in a single secreted protein, a serine/threonine kinase known as ROPO18, controls whether or not mice survive infection. Here, we establish the extent and nature of variation in ROP18among a collection of parasite strains from geographically diverse regions. Compared to other genes, ROP18 showed extremely high levels of diversification and changes in expression level, which correlated with severity of infection in mice. Comparison with an out-group demonstrated that changes in the upstream region that regulates expression of ROP18 led to an historical increase in the expression and exposed the protein to diversifying selective pressure. Surprisingly, only three atypically distinct protein variants exist despite marked genetic divergence elsewhere in the genome. These three forms of ROP18 are likely adaptations for different niches in nature, and they confer markedly different virulence to mice. The widespread distribution of a single mouse-virulent allele among geographically and genetically disparate parasites may have consequences for transmission and disease in other hosts, including humans

    Molecular epidemiology of camel trypanosomiasis based on ITS1 rDNA and RoTat 1.2 VSG gene in the Sudan

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    <p>Abstract</p> <p>Background</p> <p>Internal transcribed spacer one (ITS1) of the ribosomal DNA is known to be a suitable target for PCR-based detection of trypanosomes. The analysis of this region provides a multi-species-specific diagnosis by a single PCR. Using ITS1 primer-based PCR, a cross sectional study was carried out in the period from September to November 2009 on samples collected from 687 camels from geographically distinct zones in the Sudan to detect all possible African trypanosomes, which can infect camels.</p> <p>Results</p> <p>The results showed that all PCR-positive camels were infected with a single parasite species; <it>Trypanosoma evansi</it>. The highest prevalence, 57.1% (117/205), was observed in the Butana plains of mid-Eastern Sudan and the lowest, 6.0% (4/67), was in the Umshadeeda eastern part of White Nile State. In another experiment, the RoTat 1.2 gene encoding the variable surface glycoprotein (VSG) of <it>T. evansi </it>was analyzed for its presence or absence by a polymerase chain reaction (PCR) using <it>T. evansi </it>species-specific primers. The study showed that the RoTat 1.2 VSG gene was absent in thirteen out of thirty <it>T. evansi</it>-positive samples.</p> <p>Conclusions</p> <p>It is concluded that camel trypanosomiasis in Sudan is apparently caused by a single parasite species <it>T. evansi </it>and there were no other typanosomes species detected. In addition, the disease is highly prevalent in the country, which strengthens the need to change control policies and institute measures that help prevent the spread of the parasite. To our knowledge, this is the first molecular diagnosis report, which gives a picture of camel trypanosomiasis covering large geographical areas in Sudan.</p

    Risk Factors for Anthroponotic Cutaneous Leishmaniasis at the Household Level in Kabul, Afghanistan

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    Cutaneous leishmaniasis is a vector-borne protozoan disease that is characterized by cutaneous lesions which develop at the site of the insect bite. Lesions can vary in severity, clinical appearance, and time to cure; in a proportion of patients lesions can become chronic, leading to disfiguring mucosal leishmaniasis or leishmaniasis recidvans. Albeit not fatal, cutaneous leishmaniasis can have a significant social impact as it may lead to severe stigmatisation of affected individuals when lesions or scars occur on the face and exposed extremeties. Over the last 10–20 years there has been an increase in the number of leishmaniasis cases reported in South Asia, particularly in Afghanistan. Little is known about the household-level risk factors for infection and disease. Here we confirm previous reports that had shown the association of cutaneous leishmaniasis with age and clustering of cases at the household-level. Additionally, we show that risk of cutaneous leishmaniasis is associated with household construction (i.e. brick walls) and design (i.e. proportion of windows with screens)
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