Health and Wellbeing of the Nepalese population: Access and experiences of health and social care services in the UK

To date there has been very little research on the health and well-being of Nepali citizens living int the UK. This mixed-methods study is crucial as the NHS and social services have minimal awareness of the specific health and related social care needs of the UK Nepali community compared to other larger Black and Minority Ethnic (BME) communities. Therefore, this study aims to identify health and social care needs to promote positive health and wellbeing for the Nepali population in the UK. It also assesses health inequalities amongst the Nepali population focusing on the need for national level prioritisation to reduce these inequalities experienced by the broader UK Nepali population using NHS services

Time Trend of the Suicide Incidence in India: a Statistical Modelling

Background: It is estimated that over 100,000 people die by suicide in India every year. India alone contributes to more than 10% of suicides in the world. The suicide rate in India has been increasing steadily and has reached 11.2 (per 100,000 of population) in 2011 registering 78% increase over the value of 1980 (6.3). Objective: Objective of the study was to forecasts the suicide incidence of India up to 2020. Material and Methods: Theoretical statistics was used for the statistical modelling of the retrospective data of suicide incidence data of 1989-2011 years collected from National Crime Records Bureau (NCRB). Results: Using curve fitting method, Linear, Logarithmic, Inverse, Quadratic, Cubic, Compound, Power and Exponential growth models were validated. Cubic Model was the best fitted model with R2>0.90, p<0.01. Suicide incidence of India has an increasing trend. In 2020, it is estimated that the suicide incidence of India will be 109814 with CI [ 86,593, 133,034] for male, 76224 with CI [55,151, 97,297] for female and 186038 with CI [145,605, 226,471] for total [both male and female]. Conclusion: Suicide incidence of India has an increasing trend. India requires the involvement of all governments and other organizations to contribute to the cause of suicide awareness and prevention through activities, events, conferences and campaigns to solve this public health problem

The Fire Within: Microbes Inflame Tumors

The immune system and the microbiota mutually interact to maintain homeostasis in the intestine. However, components of the microbiota can alter this balance and promote chronic inflammation, promoting intestinal tumor development. We review recent advances in understanding the complex interactions between the microbiota and the innate and adaptive immune systems and discuss their potential to lead us in new directions for understanding cancer biology and treatment

The transfer and fate of Pb from sewage sludge amended soil in a multi-trophic food chain: a comparison with the labile elements Cd and Zn

The contamination of agroecosystems due to the presence of trace elements in commonly used agricultural materials is a serious issue. The most contaminated material is usually sewage sludge, and the sustainable use of this material within agriculture is a major concern. This study addresses a key issue in this respect, the fate of trace metals applied to soil in food chains. The work particularly addresses the transfer of Pb, which is an understudied element in this respect, and compares the transfer of Pb with two of the most labile metals, Cd and Zn. The transfer of these elements was determined from sludge-amended soils in a food chain consisting of Indian mustard (Brassica juncea), the mustard aphid (Lipaphis erysimi) and a predatory beetle (Coccinella septempunctata). The soil was amended with sludge at rates of 0, 5, 10 and 20 % (w/w). Results showed that Cd was readily transferred through the food chain until the predator trophic level. Zn was the most readily transferred element in the lower trophic levels, but transfer to aphids was effectively restricted by the plant regulating shoot concentration. Pb had the lowest level of transfer from soil to shoot and exhibited particular retention in the roots. Nevertheless, Pb concentrations were significantly increased by sludge amendment in aphids, and Pb was increasingly transferred to ladybirds as levels increased. The potential for Pb to cause secondary toxicity to organisms in higher trophic levels may have therefore been underestimated