36,406 research outputs found
Decomposition tables for experiments. II. Two--one randomizations
We investigate structure for pairs of randomizations that do not follow each
other in a chain. These are unrandomized-inclusive, independent, coincident or
double randomizations. This involves taking several structures that satisfy
particular relations and combining them to form the appropriate orthogonal
decomposition of the data space for the experiment. We show how to establish
the decomposition table giving the sources of variation, their relationships
and their degrees of freedom, so that competing designs can be evaluated. This
leads to recommendations for when the different types of multiple randomization
should be used.Comment: Published in at http://dx.doi.org/10.1214/09-AOS785 the Annals of
Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical
Statistics (http://www.imstat.org
Decomposition tables for experiments I. A chain of randomizations
One aspect of evaluating the design for an experiment is the discovery of the
relationships between subspaces of the data space. Initially we establish the
notation and methods for evaluating an experiment with a single randomization.
Starting with two structures, or orthogonal decompositions of the data space,
we describe how to combine them to form the overall decomposition for a
single-randomization experiment that is ``structure balanced.'' The
relationships between the two structures are characterized using efficiency
factors. The decomposition is encapsulated in a decomposition table. Then, for
experiments that involve multiple randomizations forming a chain, we take
several structures that pairwise are structure balanced and combine them to
establish the form of the orthogonal decomposition for the experiment. In
particular, it is proven that the properties of the design for such an
experiment are derived in a straightforward manner from those of the individual
designs. We show how to formulate an extended decomposition table giving the
sources of variation, their relationships and their degrees of freedom, so that
competing designs can be evaluated.Comment: Published in at http://dx.doi.org/10.1214/09-AOS717 the Annals of
Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical
Statistics (http://www.imstat.org
Adaptive control system for line-commutated inverters
A control system for a permanent magnet motor driven by a multiphase line commutated inverter is provided with integration for integrating the back EMF of each phase of the motor. This is used in generating system control signals for an inverter gate logic using a sync and firing angle (alpha) control generator connected to the outputs of the integrators. A precision full wave rectifier provides a speed control feedback signal to a phase delay rectifier via a gain and loop compensation circuit and to the integrators for adaptive control of the attenuation of low frequencies by the integrators as a function of motor speed. As the motor speed increases, the attenuation of low frequency components by the integrators is increased to offset the gain of the integrators to spurious low frequencies
Prospects for improved branching fractions
The experimental uncertainty on the branching fraction \b(\Lambda_c \to p
K^- \pi^+) = (5.0 \pm 1.3)% has not decreased since 1998, despite a much
larger data sample. Uncertainty in this quantity dominates that in many other
quantities, including branching fractions of to other modes,
branching fractions of -flavored baryons, and fragmentation fractions of
charmed and bottom quarks. Here we advocate a lattice QCD calculation of the
form factors in (the case
is simpler as the mass of the lepton can be neglected). Such a calculation
would yield an absolute prediction for the rate for . When combined with the lifetime, it could provide
a calibration for an improved set of branching fractions as long as
the accuracy exceeds about 25%.Comment: 8 pages, 2 figures, version to be published in Phys.\ Rev.\
Thermal capacitator design rationale. Part 1: Thermal and mechanical property data for selected materials potentially useful in thermal capacitor design and construction
The thermal properties of paraffin hydrocarbons and hydrocarbon mixtures which may be used as the phase change material (PCM) in thermal capacitors are discussed. The paraffin hydrocarbons selected for consideration are those in the range from C11H24 (n-Undecane) to C20H42 (n-Eicosane). A limited amount of data is included concerning other properties of paraffin hydrocarbons and the thermal and mechanical properties of several aluminum alloys which may find application as constructional materials. Data concerning the melting temperature, transition temperature, latent heat of fusion, heat of transition, specific heat, and thermal conductivity of pure and commercial grades of paraffin hydrocarbons are given. An index of companies capable of producing paraffin hydrocarbons and information concerning the availability of various grades (purity levels) is provided
Characterization of the PCMBS-dependent modification of KCa3.1 channel gating.
Intermediate conductance, calcium-activated potassium channels are gated by the binding of intracellular Ca(2+) to calmodulin, a Ca(2+)-binding protein that is constitutively associated with the C terminus of the channel. Although previous studies indicated that the pore-lining residues along the C-terminal portion of S6 contribute to the activation mechanism, little is known about whether the nonluminal face of S6 contributes to this process. Here we demonstrate that the sulfhydral reagent, parachloromercuribenze sulfonate (PCMBS), modifies an endogenous cysteine residue predicted to have a nonluminal orientation (Cys(276)) along the sixth transmembrane segment (S6). Modification of Cys(276) manipulates the steady-state and kinetic behavior of the channel by shifting the gating equilibrium toward the open state, resulting in a left shift in apparent Ca(2+) affinity and a slowing in the deactivation process. Using a six-state gating scheme, our analysis shows that PCMBS slows the transition between the open state back to the third closed state. Interpreting this result in the context of the steady-state and kinetic data suggests that PCMBS functions to shift the gating equilibrium toward the open state by disrupting channel closing. In an attempt to understand whether the nonluminal face of S6 participates in the activation mechanism, we conducted a partial tryptophan scan of this region. Substituting a tryptophan for Leu(281) recapitulated the effect on the steady-state and kinetic behavior observed with PCMBS. Considering the predicted nonluminal orientation of Cys(276) and Leu(281), a simple physical interpretation of these results is that the nonluminal face of S6 forms a critical interaction surface mediating the transition into the closed conformation, suggesting the nonluminal C-terminal portion of S6 is allosterically coupled to the activation gate
Failure assessment of lightly reinforced floor slabs. I: Experimental investigation
This paper is concerned with the ultimate behavior of lightly reinforced concrete floor slabs under extreme loading conditions. Particular emphasis is given to examining the failure conditions of idealized composite slabs which become lightly reinforced in a fire situation as a result of the early loss of the steel deck. An experimental study is described which focuses on the response of two-way spanning floor slabs with various materials and geometric configurations. The tests enable direct assessment of the influence of a number of key parameters such as the reinforcement type, properties, and ratio on the ultimate response. The results also permit the development of simplified expressions that capture the influence of salient factors such as bond characteristics and reinforcement properties for predicting the ductility of lightly reinforced floor slabs. The companion paper complements the experimental observations with detailed numerical assessments of the ultimate response and proposes analytical models that predict failure of slab members by either reinforcement fracture or compressive crushing of concrete. © 2011 American Society of Civil Engineers
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