563 research outputs found

    Changing the ideological roots of prejudice: Longitudinal effects of ethnic intergroup contact on social dominance orientation

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    Social Dominance Orientation (SDO) has been reported to be strongly related to a multitude of intergroup phenomena, but little is known about situational experiences that may influence SDO. Drawing from research on intergroup contact theory, we argue that positive intergroup contact is able to reduce SDO-levels. The results of an intergroup contact intervention study among high school students (Study 1, N=71) demonstrated that SDO-levels were indeed attenuated after the intervention. Furthermore, this intervention effect on SDO was especially pronounced among students reporting a higher quality of contact. A cross-lagged longitudinal survey among adults (Study 2, N=363) extended these findings by demonstrating that positive intergroup contact is able to decrease SDO over time. Moreover, we did not obtain evidence for the idea that people high in SDO would engage less in intergroup contact. These findings indicate that intergroup contact erodes one of the important socio-ideological bases of generalized prejudice and discrimination

    Pioglitazone Prevents Capillary Rarefaction in Streptozotocin-Diabetic Rats Independently of Glucose Control and Vascular Endothelial Growth Factor Expression

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    Background/Aims: Reduction of capillary network density occurs early in the development of metabolic syndrome and may be relevant for the precipitation of diabetes. Agonists of the peroxisome proliferator-activated receptor (PPAR)-gamma transcription factor are vasculoprotective, but their capacity for structural preservation of the microcirculation is unclear. Methods: Male Wistar rats were rendered diabetic by streptozotocin and treated with pioglitazone in chow for up to 12 weeks. Capillary density was determined in heart and skeletal muscle after platelet endothelial cell adhesion molecule-1 (PECAM-1) immunostaining. Hallmarks of apoptosis and angiogenesis were determined. Results: Capillary density deteriorated progressively in the presence of hyperglycemia (from 971/mm(2) to 475/mm(2) in quadriceps muscle during 13 weeks). Pioglitazone did not influence plasma glucose, left ventricular weight, or body weight but nearly doubled absolute and relative capillary densities compared to untreated controls (1.2 vs. 0.6 capillaries/myocyte in heart and 1.5 vs. 0.9 capillaries/myocyte in quadriceps muscle) after 13 weeks of diabetes. No antiapoptotic or angiogenic influence of pioglitazone was detected while a reduced expression of hypoxia-inducible factor-3 alpha and PPAR coactivator-1 alpha (PGC-1 alpha) mRNA as well as vascular endothelial growth factor (VEGF) protein possibly occurred as a consequence of improved vascularization. Conclusion: Pioglitazone preserves microvascular structure in diabetes independently of improvements in glycemic control and by a mechanism unrelated to VEGF-mediated angiogenesis. Copyright (C) 2012 S. Karger AG, Base

    Prenatal stress exposure is associated with increased dyspnea perception in adulthood

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    The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Dyspnoea is the aversive cardinal symptom in various prevalent conditions such as respiratory, cardiovascular and neuromuscular diseases and is associated with great individual and socioeconomic burden [1]. Over the past years, several physiological and also psychological factors have been demonstrated to affect the perception of dyspnoea [1, 2]. For example, high levels of anxiety in adulthood were associated with increased dyspnoea perception in patients with asthma or chronic obstructive pulmonary disease (COPD), but also in healthy controls [2]. Moreover, adverse, separation-related experiences in childhood were linked to the subsequent development of increased anxiety and dyspnoea [3]. However, the effects of adverse experiences in early, prenatal life on dyspnoea perception remain widely unknown, although prenatal exposure to maternal stress and anxiety has convincingly been related to the development of other health and behavioural problems later in life, including impairments of the respiratory control system and high anxiety levels [4–9]. Therefore, this study investigated the relationship between prenatal exposure to maternal stress and the perception of dyspnoea in adulthood 28 years later

    Choose your (international) contacts wisely: A multilevel analysis on the impact of intergroup contact while living abroad

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    A two year longitudinal study examined the influence of social contact abroad on student sojourners? cultural adjustment and intergroup affect. Social contact was measured with regard to the three people that sojourners (exchange students) spent most time with. Both the quality of the relationship with each contact and the cultural background (host national, co-national) of each contact were measured, that is contact quality and contact source, respectively. The data were analysed through repeated measures multilevel modelling. Results indicate that good quality contact (independent of source) is associated with higher cultural adjustment in sojourners and lower levels of stress. Contact quality however, was not associated with intergroup affect. Source of contact was found to matter, especially over time. Specifically, in the later stages of the sojourn, having more co-national contacts among ones three most frequent contacts, was associated with higher levels of stress, reduced cultural adjustment and higher secondary outgroup derogation. These findings suggest that who sojourners have contact with, matters for both cultural adjustment and intergroup affect
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