800 research outputs found

    Whodunit ! Assessing Copyright Liability in Cyburbia: Positing Solutions to Curb the Menace of Copyrighted ‘File Sharing’ Culture

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    The electronic age has kick started the information boom and with an everincreasing pace, it has begun to spread its canvas to engulf mankind as its greatest beneficiary andperhaps its most susceptible slave. This is evident from the universal phenomenon of copyrightedfile sharing culture promoted by P2P technologies. Indeed, the P2P architecture poses a threat to theentertainment and software industries which stand on the legislative guarantee of copyright laws.But technological advances have not only caused legislative obsolescence , but have also altered thedynamics of information exchange in the online environment. The word ‘State’ seems to have lostits meaning somewhere. Therefore, there is a pressing need on us, as an International society, todevise alternative solutions and approaches to substantially curb the abuse of digital copyrightedworks, for copyright laws to have any meaning. It is this global concern which gives birth to thispaper

    Revisiting the Historical ‘Copy-wrongs’ of ‘Copy-rights’! Are We Resurrecting the Licensing Era?

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    This article examines the historical underpinnings of copyright from the century’s old Pre Gutenberg times when print did not exist and traces a timeline as to how the bricks of the first copyright legislation in the world - The Statute of Anne, 1710 were legislated into existence. One would discover that the very origin of copyright law at the time when it was not codified was diametrically contrary to the present understanding of the codified copyright law, which originally protected the publisher as against the author. Copyright law was a tool for the State to exercise censorship over writings hostile to the Church or Government. The protection of intellectual works was influenced by the economics of publication rather than the economics of authorship. This form of an intellectual property right has its historical foundations tainted with all such objectives which would humour today’s intellectual creator

    Machine Tool Crack Detection using Operational Modal Characteristics

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    Machine tool crack detection is to detect any damages in the tool during machining and to predict the breakage of the tool by identifying the appearance of small cracks in the tool during machining. Machine tool state monitoring is critical for controlling the work piece quality and production continuity in the case of mass production. For assessing tool breakage, machine tool vibration monitoring is a suitable means. The results obtained in FE analysis are validated with experimental data. This work gives a methodology for online crack detection in machine tools. This work presents an experimental technique for measuring modal parameters of a rectangular aluminium plate with cantilever boundary condition using only the output data, with the intention to apply the technique to machine tools. Operational modal analysis is be used for damage detection by determining the depth as well as the position of tool cracks. The results obtained are validated with finite element analysis. To locate the crack, 3D graphs of the normalized frequency in terms of the crack depth and location are plotted. The intersection of these contours gives crack location and crack depth. Out of several case studies conducted the results of one of the case study is presented to demonstrate the applicability and efficiency of the method suggested

    Stability and Vibrational Analysis of a Flexible Damped Rotor System using Finite Element Method

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    Dynamic stability of a damped flexible Rotor system is studied in this work. Analysis of a damped rotating shaft with multiple discs are carried out by, varying the rotor offset positions in order to investigate the effect on critical speed and frequency of the system. From this analysis, it is observed that by varying the rotor offset positions, the modal mass participation varies and which in turn cause a variation in the critical speed and frequency of the system. This study also extends a detailed evaluation of damped rotor stability. Through this analysis it is observed that the system become unstable beyond its critical speed. The stabilizing effects of anisotropic bearing stiffness and external damping are also demonstrated. The effect of unbalance in the rotating machinery is evaluated in the last section

    A prospective pharmacovigilance study to evaluate adverse effect profile of first line anti-tubercular drugs in newly diagnosed sputum positive patients

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    Background: Tuberculosis (TB) continues to remain one of the most pressing health problems in India with highest TB burden country in the world. Anti-tubercular therapy (ATT) induced organ toxicities are potentially serious ADRs of first line ATT regimen. The underlying mechanism of ATT-induced ADRs especially hepatotoxicity and the factors predisposing to its incidence which is significantly high in Indians are not clearly understood. It's vital to emphasize on ATT induced ADRs as it has direct influence on therapeutic outcome; result in high dropout rate and potential to develop MDR/XDR cases. ADR monitoring help us to revise the treatment protocol thereby improve treatment adherence and therapeutic outcome. Objective of this study is therefore designed to explore and monitor ADRs of first line anti-TB drugs.Methods: In this prospective observational study 60 TB patients (18-70 yrs) of either sex, newly sputum positive with normal parameters were included. Patients were followed up for six months aiming primarily to assess rate of ADRs and to identify preventable and potentially serious ADRs of anti-TB drugs. The ADRs of ATT on various organ systems (heart, kidney and liver), biochemical and haematological parameters were assessed and compared after 2 and 6 months; gender and age specific adverse events were also studied. Data obtained was analysed using student’s t-test of OpenEpi statistical software.Results: Study clearly revealed that ATT exhibit significant increase in toxicity markers viz. liver enzymes (p<0.01), urea and creatinine (p<0.01), ESR (p<0.05) and PTINR (p<0.01), wherein decrease in Hb% (p<0.01) when compared to baseline.Conclusions: ATT related ADRs is the major cause of dropouts and development of MDR/XDR cases. It's crucial to develop strategies to ameliorate ADRs both to improve the quality of patient care and to control TB safely. The data obtained from present study may be helpful in developing these effective strategies

    Dichotomous development of the gut microbiome in preterm infants.

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    BackgroundPreterm infants are at risk of developing intestinal dysbiosis with an increased proportion of Gammaproteobacteria. In this study, we sought the clinical determinants of the relative abundance of feces-associated Gammaproteobacteria in very low birth weight (VLBW) infants. Fecal microbiome was characterized at ≤ 2 weeks and during the 3rd and 4th weeks after birth, by 16S rRNA amplicon sequencing. Maternal and infant clinical characteristics were extracted from electronic medical records. Data were analyzed by linear mixed modeling and linear regression.ResultsClinical data and fecal microbiome profiles of 45 VLBW infants (gestational age 27.9 ± 2.2 weeks; birth weight 1126 ± 208 g) were studied. Three stool samples were analyzed for each infant at mean postnatal ages of 9.9 ± 3, 20.7 ± 4.1, and 29.4 ± 4.9 days. The average relative abundance of Gammaproteobacteria was 42.5% (0-90%) at ≤ 2 weeks, 69.7% (29.9-86.9%) in the 3rd, and 75.5% (54.5-86%) in the 4th week (p &lt; 0.001). Hierarchical and K-means clustering identified two distinct subgroups: cluster 1 started with comparatively low abundance that increased with time, whereas cluster 2 began with a greater abundance at ≤ 2 weeks (p &lt; 0.001) that decreased over time. Both groups resembled each other by the 3rd week. Single variants of Klebsiella and Staphylococcus described variance in community structure between clusters and were shared between all infants, suggesting a common, hospital-derived source. Fecal Gammaproteobacteria was positively associated with vaginal delivery and antenatal steroids.ConclusionsWe detected a dichotomy in gut microbiome assembly in preterm infants: some preterm infants started with low relative gammaproteobacterial abundance in stool that increased as a function of postnatal age, whereas others began with and maintained high abundance. Vaginal birth and antenatal steroids were identified as predictors of Gammaproteobacteria abundance in the early (≤ 2 weeks) and later (3rd and 4th weeks) stool samples, respectively. These findings are important in understanding the development of the gut microbiome in premature infants

    Survey on Encryption Techniques in Delay and Disruption Tolerant Network

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    Delay and disruption tolerant network (DTN) is used for long area communication in computer network, where there is no direct connection between the sender and receiver and there was no internet facility. Delay tolerant network generally perform store and forward techniques as a result intermediate node can view the message, the possible solution is using encryption techniques to protect the message. Starting stages of DTN RSA, DES, 3DES encryption algorithms are used but now a day\u27s attribute based encryption (ABE) techniques are used. Attribute based encryption technique can be classified in to two, key policy attribute based encryption (KPABE) and cipher policy attribute based encryption (CPABE). In this paper we perform a categorized survey on different encryption techniques presents in delay tolerant networks. This categorized survey is very helpful for researchers to propose modified encryption techniques. Finally the paper compares the performance and effectiveness of different encryption algorithms

    A Workflow-centric Study of Organizational Knowledge Distribution

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    Organizations require mechanisms to efficiently distribute knowledge such as news releases, seminar announcements, and memos. While the machinery for information storage, manipulation. and retrieval exists, research dealing directly with knowledge distribution in an organizational context is scarce. In this paper, we address this need by first examining the pros and cons of the conventional "mailing lists" approach and then proposing new workflow mechanisms that improve the efficiency and effectiveness of knowledge distribution. The main contributions of this study include: (I) a workflow perspective on organizational knowledge distribution. (2) workflow analysis of two new knowledge distribution methods based on dynamic mailing lists and profile matching, respectively, and (3) a new way of matching knowledge supply and demand that extends existing information filtering algorithms.Information Systems Working Papers Serie
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