Alterations of GABAergic neuron-associated extracellular matrix and synaptic responses in Gad1-heterozygous mice subjected to prenatal stress

浜松医科大学博士（医学）doctoral医学系研究科thesi

予科思いだすことども

Articledepartmental bulletin pape

“IZUME”: Child-care Baskets Painted on Genre Folding Screens in Late Medieval Japan

departmental bulletin pape

Acute myeloid leukemia in the elderly : 159 Nagoya case studies

1999-11To obtain background information on elderly acute myeloid leukemia (AML), unselected data covering 159 patients aged 60 years or over with AML from 14 hospitals in Nagoya, Japan was analyzed retrospectively. Among these patients, 119 had de novo acute AML, 32 had AML which evolved from myelodysplastic syndrome (MDS-AML), and 8 had other types of leukemia. The survey showed that MDS-AML tended to be more prevalent in patients aged 70 years and older and that MDS-AML showed a significantly more severe degree of leukopenia and anemia than de novo AML. MDS-AML also showed a significantly lower complete remission (CR) rate than that of de novo AML [6.9% (2/29) vs 58.3% (67/11), P < 0.01] and significantly shorter survival times than those of de novo AML [median: 3.6 months vs 9.6 months, P < 0.01 (generalized Wilcoxon test; GW]. In de novo AML, the proportion of patients treated with conventional therapy (CT group) decreased significantly, and that of those with attenuated therapy (AT group) increased significantly as age elevated (P < 0.01). The CT group showed a significantly higher CR rate (65.4% vs 41.2%, P < 0.05) and a significantly longer survival period than those of the AT group [median: 11.6 months vs 4.8 months, P < 0.05 (GW)]. Overall survival rates of the older age groups became significantly shorter with aging [P < 0.01 (GW)].departmental bulletin pape

小学校におけるロボット教材を用いた情報教育

text紀要論文 / Departmental Bulletin Paperdepartmental bulletin pape

Improved measurements of branching fractions and CP partial rate asymmetries for B-->omegaK and B-->omegapi

journal articl

Hypertension therapy and cardiovascular protection. Effects of angiotensin II receptor block with Valsartan

OBJECTIVES: Arterial hypertension and its pharmacological control are discussed in view of the high cardiovascular risk due to lack of target blood pressure achievement. It is, therefore, underlined the need for a highly effective therapy, able to provide protection from organ damage through a marked antihypertensive activity. In addition to this basic property, also compliance of the patient to therapy is needed, in order to avoid that the effects of therapeutic measures should result fruitless. DISCUSSION AND CONCLUSIONS: An answer to this problem appears now offered by a recent class of antihypertensive agents, the angiotensin II receptor blockers (ARBs). Among them valsartan has been described, providing an overview of methodologically adequate clinical studies, evaluating the efficacy, even at long-term, and safety. Valsartan has been compared with other antihypertensive agents of proven efficacy, mainly amlodipine, showing a better clinical profile. A wide room was finally left to the problem of adherence to therapy, whose lack is associated very frequently with marked increases in cardiovascular risk, due to absent or insufficient blood pressure control. This implies significant increases of health costs, as documented in numerous Countries, mainly following the higher need for hospitalization. On the other hand, it is also well documented the pharmacoeconomic benefit associated to ARBs use, particularly with valsartan

[卒業研究要旨]郊外住宅地居住者の日常的移動に関する課題についての研究―大阪府豊能町の場合―

departmental bulletin pape

The distribution of probe correlations to the gene expression index (), through 12 independent measurements of 3278 genes using 7–8 probes per gene

<p><b>Copyright information:</b></p><p>Taken from "OligoWiz 2.0—integrating sequence feature annotation into the design of microarray probes"</p><p>Nucleic Acids Research 2005;33(Web Server issue):W611-W615.</p><p>Published online 27 Jun 2005</p><p>PMCID:PMC1160160.</p><p>© The Author 2005. Published by Oxford University Press. All rights reserved</p> The plot illustrates that the majority of the probes agree with the gene expression index

Driving Mechanism of a Travelling Wave Ultrasonic otor : Analysis of Inverse Rotation Phenomenon

departmental bulletin pape