89 research outputs found

    Pengaruh Penggunaan Limbah Tapioka sebagai Sumber Belajar terhadap Motivasi dan Hasil Belajar Siswa

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    : This aim of this research is to know (1) the differences of students\u27 motivation and achievement after using tapioca waste as learning resource in tenth grade, MAN 2 Pati in Archaebacteria and Eubacteria materials: (2) the effects of using tapioka waste as learning resources on students\u27 motivation and achievement in tenth grade, MAN 2 Pati. This research is quasi-experimental design with randomized control group, pre-post test. The study population was all students of Class X MAN 2 Pati, while the research sample is Class X-2 as the control group and Class X-3 as the experimental group. Data collection techniques were test and non-test techniques. The analyses used the t-test to determine differences in motivation and achievement. The results show that there is difference in learning motivation after using tapioca waste as a source of learning, indicated by the result of paired samples t-test, value of sig.(2-tailed)>α. There is no difference in learning achievement after using tapioca waste as a source of learning, which is indicated by paired sample t-test, the value of sig.(2-tailed)<α. Learning motivation and achievement of students who use tapioca waste as learning resources is higher than that of students who use the conventional learning resources

    The Relationship Between Multiple Intelligences with Preferred Science Teaching and Science Process Skills

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    This study was undertaken to identify the relationship between multiple intelligences with preferred science teaching and science process skills. The design of the study is a survey using three questionnaires reported in the literature: Multiple Intelligences Questionnaire, Preferred Science Teaching Questionnaire and Science Process Skills Questionnaire. The study selected 300 primary school students from five (5) primary schools in Penang, Malaysia. The findings showed a relationship between kinesthetic, logical-mathematical, visual-spatial and naturalistic intelligences with the preferred science teaching. In addition there was a correlation between kinesthetic and visual-spatial intelligences with science process skills, implying that multiple intelligences are related to science learning

    フロン代替有機溶剤の生物学的モニタリング

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    1.雌性ラットを100,300,1000ppmの2-ブロモプロパンに1日8時間、9週間連続曝露し,卵巣の変化を観察した。300,1000ppmの両曝露群で両依存的に始原、成長、antralいずれの卵胞も減少していた。また、同じく雌性ラットを3000ppmの2-ブロモプロパンに8時間の曝露後、1,3,5,17日後の卵巣の変化を観察したところ,時間の経過とともに卵母細胞の変化がより顕著にみとめられた。また、卵母細胞と顆粒細胞のアポトーシスの所見は5、17日後に多くみられた。この結果から2-ブロモプロパンによる卵巣機能障害はアポトーシスによって引き起こされていること,2-ブロモプロパンによる障害のモニタリングには膣スメアの観察よりも卵胞の種類別数を調べることでより鋭敏にできることが示唆された。 2.ラットを4群に分け、1-ブロモプロパン800、400、200ppmに1日8時間、12週間曝露した。前脚握力、後脚握力、神経伝導速度を曝露直前、及び曝露開始後4週間毎に測定した。曝露終了時に全血採血し、血液生化学検査も行った。前肢握力、後肢握力が濃度依存的、期間依存的に弱くなった。800ppmで神経電動速度は対照群に比べ、有意に減少した。血液中CPK活性は量依存的に減少した。 3.中国宜興市にある1-ブロモプロパン製造工場に働く24名の女性、13名の男性労働者を対象に、自覚症状、パッシブサンプラーによる曝露濃度の時間加重平均値、尿中1-ブロモプロパン濃度、血漿CK活性を調べた。さらに環境中1-ブロモプロパン濃度を検知管で測定した。作業中の自覚症状として粘膜刺激症状が最も多かったが、めまいなどの中枢神経症状もみられた。26人の個人曝露量と尿中1-ブロモプロパン量との関係は有意な相関を示した。血漿CK活性と曝露量との相関はスピアマンの係数で有意であったが、男性、女性別での分析では有意でなかった。科学研究費補助金 研究種目:基盤研究(C)(2) 課題番号:10670348 研究代表者:柴田 英治 研究期間:1998-1999年度research repor

    Fine-tuned cholesterol solubilizer, mono-6-O-α-D-maltosyl-γ-cyclodextrin, ameliorates experimental Niemann-Pick disease type C without hearing loss.

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    application/pdfNiemann-Pick disease type C (NPC) is a fatal disorder with abnormal intracellular cholesterol trafficking resulting in neurodegeneration and hepatosplenomegaly. A cyclic heptasaccharide with different degrees of substitution of 2-hydroxypropyl groups, 2-hydroxypropyl-β-cyclodextrin (HP-β-CD), acts as a strong cholesterol solubilizer and is under investigation for treating this disease in clinical trials, but its physicochemical properties and ototoxicity remain a concern. Here, we evaluated the potential of mono-6-O-α-maltosyl-γ-CD (G2-γ-CD), a single-maltose-branched cyclic octasaccharide with a larger cavity than HP-β-CD, for treating NPC. We identified that G2-γ-CD ameliorated NPC manifestations in model mice and showed lower ototoxicity in mice than HP-β-CD. To investigate the molecular mechanisms of action behind the differential ototoxicity of these CDs, we performed cholesterol solubility analysis, proton nuclear magnetic resonance spectroscopy, and molecular modeling, and estimated that the cholesterol inclusion mode of G2-γ-CD maintained solely the 1:1 inclusion complex, whereas that of HP-β-CD shifted to the highly-soluble 2:1 complex at higher concentrations. We predicted the associations of these differential complexations of CDs with cholesterol with the profile of disease attenuation and of the auditory cell toxicity using specific cell models. We proposed that G2-γ-CD can serve as a fine-tuned cholesterol solubilizer for treating NPC, being highly biocompatible and physicochemically suitable for clinical application

    Study of CP-Violating Asymmetries in B0→π+π- Decays

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    Nuclear extracts were prepared from synchronous cultures containing ring (R), trophozoites (T) and schizonts (S) stage parasites

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    Arrows indicate the DNA-protein complexes. Lower panel shows the reporter gene activity of each promoter at three developmental stages (Fig 4, for comparison purposes).<p><b>Copyright information:</b></p><p>Taken from "Distinct and stage specific nuclear factors regulate the expression of falcipains, cysteine proteases"</p><p>http://www.biomedcentral.com/1471-2199/9/47</p><p>BMC Molecular Biology 2008;9():47-47.</p><p>Published online 14 May 2008</p><p>PMCID:PMC2409366.</p><p></p

    Distinct and stage specific nuclear factors regulate the expression of falcipains, cysteine proteases-0

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    Ds. genes are indicated as grey boxes. The orientation of the genes are denoted by +/- signs.<p><b>Copyright information:</b></p><p>Taken from "Distinct and stage specific nuclear factors regulate the expression of falcipains, cysteine proteases"</p><p>http://www.biomedcentral.com/1471-2199/9/47</p><p>BMC Molecular Biology 2008;9():47-47.</p><p>Published online 14 May 2008</p><p>PMCID:PMC2409366.</p><p></p

    Distinct and stage specific nuclear factors regulate the expression of falcipains, cysteine proteases-7

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    N start sites. Positions downstream of the ATG are denoted with a (+) sign and those upstream with a (-) sign. Thick lines denote regions before the transcription start site. Thin lines denote regions after the start site. Arrows denote the primers and their positions used for 5'RACE. (B) Agaorse gel electrophoresis of 5'RACE products. Lane M, DNA size markers. Arrows denotes the PCR amplified products.<p><b>Copyright information:</b></p><p>Taken from "Distinct and stage specific nuclear factors regulate the expression of falcipains, cysteine proteases"</p><p>http://www.biomedcentral.com/1471-2199/9/47</p><p>BMC Molecular Biology 2008;9():47-47.</p><p>Published online 14 May 2008</p><p>PMCID:PMC2409366.</p><p></p
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