羟基甲氧基苯甲醛在化妆品中起增白作用的研究

采用酶学动力学方法研究2-羟基-4-甲氧基苯甲醛(HMB)对酪氨酸酶的单酚酶和二酚酶活力的抑制效应。结果表明,HMB对酪氨酸酶单酚酶的效应只表现对稳态活力有明显的抑制作用,但对酶作用的迟滞时间没有影响;随着抑制剂浓度增大,单酚酶活力呈指数下降,导致酶活力下降50%的抑制剂浓度(IC50)为0 352mmol·L-1。HMB对二酚酶的抑制作用表现为可逆过程,IC50为0 164mmol·L-1;抑制作用机理研究表明HMB是一种混合型抑制剂,其抑制常数KI和KIS分别为0 131mmol·L-1和0 253mmol·L-1。通过对HMB抑制酪氨酸酶机理的研究,阐明HMB作为化妆品添加剂的增白作用机理

Study on the Estimation Algorithm of the Temperature Based on Mid-Wave Infrared Remote Sensing

高于绝对零度的物体满足Plank定律,因此红外辐射在一定程度上反映温度。红外辐射测温具有响应速度快,分辨率高,能较好的实现对微小、高速移动等不可接触测量目标的温度测量。用一种先进的双波段红外遥感光谱系统采集不同温度金属的红外发射光谱,分析和研究这些不同温度的光谱数据所具有的不同特征。在此基础上,对样本提取重心位置、波峰位置、波长λ1的值、波长λ2的值四种光谱特征,寻找温度与其之间的函数关系;并建立多元线性回归模型,通过光谱反推温度值。实验结果表明,该方法可以有效的分辨有明显温差的高温物体,在实验所测温度范围内的测温绝对误差小于30℃,在测量误差小于20℃的置信区间内有98%正确率,优于一般系统需要保证目标发射率、大气透射率、环境等效辐射温度等复杂参数高精度的情况下2%的测温精度。该方法可以简单有效的对远距离目标测温,从而进一步拓展红外光谱遥测温度的应用领域。Since objects above absolute zero agree with the Plank law,the objects' temperature is reflected by the infrared radiation.With fast response and high resolution,temperature estimation based on mid-wave infrared remote sensing could realize the temperature measurement for small,high-speed and touch-free objects.A new optical system for infrared(IR)image-spectrum integration remote sensing was used to acquire infrared emission spectra from different temperatures of metal.With this basis,we extracted four appropriate spectral features which were the center of gravity position,peak position,the value of wavelengthλ1and the value of wavelengthλ2from the training samples.The relationship between temperature and these features was studied.A multiple linear regression model was established to estimate the temperatures from the spectra.The experimental results showed that,the method could distinguish hot objects with obvious temperature differences.The absolute error was less than 30℃in the experimental temperature range.The accuracy was 98%in the range that the measurement error was less than 20 ℃,which was better than the 2% precision of the general system with the complex strict emissivity,atmospheric transmittance,environmental equivalent radiation temperature and some other parameters.This method could measure the temperature of the remote objects in a simple and effective way,and so could expand the application field of temperature estimation based on infrared remote sensing.中央高校基本科研业务专项资金项目(XMU2013121018);; 国家自然科学基金项目(61404112,61571381);; 福建省自然科学基金项目(2012J01413)资

环氧乙烷化工设计安全事项分析

针对环氧乙烷在生产、储存、运输和使用环节中存在的安全问题,对环氧乙烷特殊的物理化学性质进行分析.环氧乙烷化学性质非常活泼,易开环并释放大量热量,在空气中的爆炸极限浓度为3%～100%,引燃能最小只需0.06 mJ,易燃易爆.结合其自身反应特性及易自聚、歧化或分解等特点,讨论了其在安全操作、化工设计中的注意事项,并提出了具体建议措施,包括相关装置布置方案设计、安全温度和压力设计、设备安全及紧急处理设计等,以期能提高环氧乙烷在生产、运输和使用过程中的安全性和可靠性,减少相关事故的发生.</p

Synthesis,Characterization and Crystal Structure of Lanthanide β-Phenylacrylate Complexes

合成了β-苯基丙烯酸与稀土的14种配合物，经分析测定其组成为rEl3（rE=y，lA~yb，Hl=β-C6H5CH＝CHCOOH）.用Ir、nMr和单晶X射线衍射等技术对此类配合物的性质及晶体结构进行了研究.结果表明，Erl3为单斜晶系，P21空间群.在每个配位单元中，Er与来自6个羧酸根的7个氧原子配位，形成畸变的五角双锥配位多面体.Fourteen coordinattion compounds of lanthanide, β-phenylacrylate, were synthesized and characterized as REL3(RE=Y, La-Yb, HL=β-C6H5CH = CHCOOH) by chemical analysis, IR and NMR spectra and X-ray structure analysis.The crystal of ErL3 crystallizes in monoclinic system with space group P21.Each Er atom was coordinated with sevenoxygen atoms From six β-phenylacrylate groups Forming a distorted pentagonal bipyramidconFiguration.浙江省教育委员会基

甲基丙烯酸甲酯甲醇水共沸体系萃取分离工艺模拟

针对甲基丙烯酸甲酯-甲醇-水共沸体系,分别选择水、正己烷和水-正己烷双溶剂为萃取剂建立分离流程进行模拟,建立单溶剂、双溶剂萃取工艺过程进行全流程模拟,采用灵敏度分析优化工艺过程的溶剂比和操作温度.结果表明,双溶剂萃取工艺比水、正己烷单溶剂萃取工艺能耗分别降低15.1%和34.9%.采用绿色度评价方法量化3种分离工艺对环境的影响,水、正己烷、水-正己烷双溶剂萃取工艺的绿色度分别为–7.25,–21.3和–6.75 gd

甲基丙烯酸甲酯-甲醇-水共沸体系萃取分离工艺模拟

针对甲基丙烯酸甲酯-甲醇-水共沸体系,分别选择水、正己烷和水-正己烷双溶剂为萃取剂建立分离流程进行模拟,建立单溶剂、双溶剂萃取工艺过程进行全流程模拟,采用灵敏度分析优化工艺过程的溶剂比和操作温度.结果表明,双溶剂萃取工艺比水、正己烷单溶剂萃取工艺能耗分别降低15.1%和34.9%.采用绿色度评价方法量化3种分离工艺对环境的影响,水、正己烷、水-正己烷双溶剂萃取工艺的绿色度分别为–7.25,–21.3和–6.75 gd

Molecular and Crystal Structure of Tri (β-Phenylacrylato) Lanthanum

标题化合物，线性多聚的三（μ-β-苯基丙烯酸）镧，被合成并得到晶体.X-衍射结构分析表明[lA（β-C6H5HCOO）3]为三方晶系，r3C空间群，晶体学数据：A=13.344（1）A，α=116.13（1）°V=1182.2（4）A3，z=2，dX=1.63g/CM3，μ=1.85MM-1，f（000）=576.573个可观察的衍射点（Ⅰ＞3σ（Ⅰ）），最终偏差因子r=0.031，rW=0.036.在每个配位单元中，lA与来自六个羧酸根的九个氧原子配位.晶体结构由沿晶胞体对角线方向无限伸展的一维聚合链组成，-lA-lA-重合于三重轴.The title compound, linear-poly [μ-β-phenylacrylato-O,O':O' ) Lanthanum ], has been synthesized and determined by X-ray single-crystal diFFraction.[La (β-C6H5CHCHCOO)3] crystallizes in the trigonal, space group R3c.Cell parameters are a= 13.344 (1 ) A,a= 116.13 (1 )°,V= 1182.2 (4) A 3,Z= 2,Dx= 1.63 g/cm3, μ= 1.85mm-1,F(000) = 576.The structure was reFined to an R of 0.031 and Rw of 0.036 For 573 observed renections.Each La atom is coordinated with nine O atoms From six carboxylato groups.The crystal structure consists of one-dimensional polymeric chains with La atoms lying on thethree-Fold axis of chains at a La-La distance of 3.991 (1) A

Ho~(3+)/Tm~(3+)共掺α-NaYF_4单晶体的光谱特性（英文）

采用坩埚下降法生长出Ho~(3+)离子掺杂浓度~1.90 mol%、Tm~(3+)不同掺杂离子浓度(0.99mol%,1.58mol%,2.37 mol%,3.16 mol%,3.99 mol%,7.19 mol%)的双掺杂立方晶相NaYF_4单晶体.根据测定的吸收光谱以及800nmLD波长激发下的发射光谱、发射截面和衰减曲线,研究从Tm~(3+)离子到Ho~(3+)离子的能量传递机制、Tm~(3+)离子的浓度猝灭效应和Ho~(3+)离子在2.04μm波段的优化发光效应.当Ho~(3+)离子浓度保持为~1.90 mol%不变,Tm~(3+)离子浓度从0.99 mol%增加到1.59mol%时,2.04μm波段的发射强度逐步增强;当浓度从1.59mol%增加到7.19mol%时,发射强度逐步减弱.Ho~(3+)(1.90 mol%)/Tm~(3+)(1.59 mol%)共掺的单晶体的发射截面最大,达到2.17×10-20 cm~2,其荧光寿命最长,为21.72ms;同时,根据Ho~(3+)离子的吸收截面和Tm~(3+)离子的发射截面,计算得到该样品从Tm~(3+)∶3F~(3+)4→Ho∶5I7稀土离子能量传递系数和Ho~(3+)∶~5I_7→Tm~(3+)∶~3F_4反传递系数分别为C_(Tm-Ho)=24.14×10~(-40)cm~6/s,C_(Ho-Tm)=2.05×10~(-40) cm~6/s

Synthesis, characterization and crystal structure of lanthanide beta-phenylacrylate complexes

Fourteen coordination compounds of lanthanide? beta-phenylacrylate, were synthesized and. characterized as REL(3)(RE=Y, La-Yb, HL=beta-C6H5CH = CHCOOH) by chemical analysis, IR and NMR spectra and X-ray structure analysis. The crystal of ErL(3) crystallizes in monoclinic system with,pace group P2(1). Each Er atom was coordinated with seven oxygen atoms from six beta-phenylacrylate groups forming a distorted pentagonal bipyramid configuration