Non-display defect detection of LCD

TFT-LCD（ThinFilmTransistor-LiquidCrystaldisplay）广泛用作智能手机、电视面板、电脑等便携电子终端的显示屏，并且市场需求逐年扩大。近年来大尺寸、高分辨、窄边框成为发展趋势，使得其工艺结构愈加复杂，线路尺寸已达到微米量级，传统的裸眼或者电气检测已经无法满足其缺陷检测的要求。自动光学检测凭借其非接触性、速度快、标准一致等优点大大提高检测效率、降低了成本，在液晶屏检测领域展现出很强的竞争优势。 自动光学检测最核心的部分是光学成像系统和图像处理算法，本论文针对TFT-LCD屏背板和面板线路的成像、背板组件缺陷检测和线路粒子压合检测三个问题进行研究，研究内容...TFT-LCD is widely used as smart phone, TV panels and other kinds of display screen, and the demand expand year by year. Along with the development, large size, high resolution, marrow border becomes a trend. The craft structure is complex, and the line size has reached the order of microns. The traditional naked eye or electrical detection has been unable to meet the requirements. Automatic optica...学位：工程硕士院系专业：物理科学与技术学院_工程硕士(电子与通信工程)学号：1982014115298

Enhancement of capacity in applied biometry in East and southern Africa

Biometric skills in developing countries are inadequate to support the changing priorities of agricultural research with the consequence that the quality of research aimed at increasing food security and alleviating poverty is often deficient because it lacks good statistical design" (CTA, 1997). It was on this basis that the workshop was planned, realising that not only do national scientists and statisticians (biometricians) need training in applied biometrics but they also need to be exposed to the range of problems and complexity of agricultural study design necessary for the developing world. Few courses in applied biometrics exist in universities in East and southern Africa. Training in biometrics provided hitherto by overseas institutions has been beneficial, but lecturers do not often have a full appreciation, or practical hands-on experience, of the special features of agricultural research and development in Africa. The subjects of experimental design, statistical analysis, interpretation and presentation of results are still recognised to be among the top priorities for training by national agricultural research system (NARS) scientists participating in collaborative networks co-ordinated by the International Livestock Research Institute (ILRI) and the International Centre for Research in Agroforestry (ICRAF). There is thus a major need to establish strong training programmes in the region itself with links to existing programmes abroad

Kilogram Scale-up Preparation of Catalysts and its Reaction Process in Syngas Methanation

甲烷化催化剂是煤制合成天然气核心技术之一,因此研发合成气完全甲烷化催化剂具有重要意义。研究工作采用实验室小试共沉淀制备甲烷化催化剂的最佳工艺条件; 方法,进行单批次1、5和10; kg级(代号cat-1、cat-5、cat-10)催化剂的制备研究。研究了催化剂制备的控制因素和放大制备催化剂的反应性能及催化反应工艺条件。研究; 显示:催化剂制备的控制因素主要包括Na~+含量及晶型结构;放大制备催化剂具有良好的活性、操作稳定性和耐热性能,与小试制备催化剂具有较好的一致性;; 放大制备催化剂(cat-10)在所考察的还原温度、反应H_2/CO比和10000~40000; mL·h~(-1)*g_(cat)~(-1)反应空速范围内具有良好的甲烷化活性。研究结果表明,该研究单批次公斤级催化剂放大制备是成功的,为实现催; 化剂进一步放大制备提供了良好基础。Methanation catalysts play a vital role in the production of synthetic; natural gas (SNG) from coal. Based on bench-scale optimum; co-precipitation conditions of catalyst preparation, scale up; preparation of catalysts for syngas methanation with single batch of 1,; 5 and 10 kg is studied. Factors affecting catalyst; preparation/performance and scale-up were investigated. The results show; that Na~+ content and crystal structure of the catalysts are the; critical factors, and the catalysts prepared under scale-up conditions; possess excellent operation stability and heat resistance, with; consistent performance as those from bench-scale samples. The 10 kg; batch has good reaction activity under studied conditions. Therefore,; the scale-up preparation is successful for the methanation catalyst in; this study, which is useful for future scale-up preparation of related; catalysts

Influence of Helicobacter pylori infection on autologous DC-CIK maintenance therapy in the advanced gastric cancer patients

目的:对比幽门螺杆菌(HElICObACTEr PylOrI,HP)感染阴性和阳性的晚期胃癌患者接受自体树突状细胞联合细胞因子诱导的杀伤(dEndrITIC CEllS-CyTOkInE InduCEd kIllEr,dC-CIk)细胞维持治疗的疗效差异。方法:收集2010年6月至2012年6月中国人民解放军第174医院肿瘤中心收治的72例晚期胃癌患者,年龄29~90岁,中位年龄56岁,通过胃镜检查进行胃癌确诊并检测HP,分为HP阳性组(45例)及HP阴性组(27例),在接受手术或/和放化疗后,接受2疗程自体dC-CIk维持治疗,比较两组外周血培养的dC分化成熟情况及临床疗效差异。结果:两组dC成熟过程形态变化无差异;HP阳性组dC表面分子Cd83、Cd86表达显著高于HP阴性组(P0.05)。HP阳性组治疗后生活质量评分(kPS)、外周血T细胞亚群(Cd3+、Cd4+、Cd8+)比例较治疗前显著提高(P0.05)。HP阳性组治疗后kPS评分、CEA和CA199表达以及Cd3+和Cd4+T细胞数量等的改善均优于HP阴性组(P0.05)。共随访2年,阳性组患者中位生存期为12.64个月,长于阴性组的11.42个月(P 0.05).Levels of CD83 and CD86 on the surface of DCs were significantly higher in the Hp-positive group than those in the Hp-negative group( P 0.05).In the Hp-positive group,the quality of life KPS score and levels of T lymphocyte markers( CD3+,CD4+and CD8+) were significantly increased( P 0.05).Hp-positive patients had better KPS score,higher levels of CEA and CA199,and more abundant CD3+CD4+T cells than Hp-negative patients( P 0.05).At the end of 2-years follow-up,the median survival time was 12.64 months in the HP-positive group and 11.42 months in the HP-negative group( P < 0.05).Conclusion: Hp infection may help stabilize the tumor size,improve the quality of life,and prolong the survival time in patients with advanced gastric cancer undergoing maintenance therapy with DC-CIK cells.南京军区医学科技创新课题资助(No.10MA068); 厦门市科技计划创新项目资助(No.3502z20134026;No.3502z20144034)~

pJAK2 polypeptide,an antagonist of suppressors of cytokine signaling-1,can enhance the antitumor effect of dendritic cells

目的:探讨细胞因子信号转导抑制因子-1(SuPPrESSOrS Of CyTOkInE SIgnAlIng1,SOCS1)拮抗物PJAk2多肽(氨基酸序列号为1001-1013)参与树突状细胞(dEndrITIC CEllS,dCS)的体外诱导培养后对dCS抗肿瘤作用的影响。方法:采集健康人外周血,离心获得单个核细胞,用重组人粒细胞巨噬细胞集落刺激因子(rECOMbInAnT HuMAn grAnulOCyTE-MACrOPHAgE COlOny STIMulATIng fACTOr,rHgM-CSf)及重组人白细胞介素-4(rECOMbInAnT HuMAn InTErlEukIn-4,rHIl-4)诱导dCS,第5天分为4组:单纯dCS培养(对照)组、抗原负载(lySATE-dCS)组、多肽修饰(PJAk2-dCS)组和抗原与多肽共培养(lySATE+PJAk2-dCS)组,第6天各组加入肿瘤坏死因子-α(TuMOr nECrOSIS fACTOr-AlPHA,Tnf-α)促成熟。倒置显微镜下观察dCS形态;fCM法检测dCS表型;乳酸脱氢酶(lACTATE dEHydrOgEnASE,ldH)细胞毒实验检测各组细胞毒性T淋巴细胞(CyTOTOXIC T lyMPHOCyTE,CTl)对胃癌细胞bgC-823的靶向杀伤作用;ElISA法检测白细胞介素-12(InTErlEukIn-12,Il-12)和γ干扰素(InTErfErOn-γ,Ifn-γ)的水平。结果:与未加入诱导剂组相比,各组均成功诱导出成熟dCS,均高表达Cd80、Cd83、Cd86和人类白细胞dr抗原(HuMAn lEukOCyTE AnTIgEn dr,HlA-dr),但以lySATE+PJAk2-dCS组的表达水平最高。在10:1~30:1的效靶比范围内,CTl杀伤作用与效靶比呈正相关。当效靶比为30:1时,对照组的CTl杀伤率达(19.77±2.34)%,低于其他3组(P<0.01),而lySATE+PJAk2-dCS组较lySATE-dCS组及PJAk2-dCS组都高(P<0.05)。lySATE+PJAk2-dCS组培养上清液中Il-12及Ifn-γ的分泌水平明显高于对照组(P<0.01)。结论:SOCS1拮抗物PJAk2多肽(1001-1013)可增强dCS对胃癌细胞的抗原递呈及特异性抗肿瘤作用。Objective:To investigate the effect of pJAK2 polypeptide,an antagonist of SOCS1(suppressors of cytokine signaling 1),on antitumor effect of in vitro cultivation-induced DCs(dendritic cells).Methods:Peripheral blood was collected from the healthy volunteers,and the PBMCs(peripheral blood mononuclear cells)were isolated.DCs were induced by rhGM-CSF(recombinant human granulocyte-macrophage colony-stimulating factor)and rhIL-4(recombinant human interleukin-4).On the fifth day,DCs were divided into four groups:control group,Lysate-DCs group,pJAK2-DCs group,and Lysate + pJAK2 DCs group.On the sixth day,TNF-α(tumor necrosis factor-alpha)was added into each group.The morphological features of DCs were observed under an inverted microscope;the phenotypes were detected by FCM(flow cytometry);the killing effect of CTLs(cytotoxic T lymphocytes)on gastric cancer BGC-823 cells was evaluated by LDH(lactate dehydrogenase)cytotoxicity test;the concentrations of IL-12(interleukin-12)and IFN-γ(interferon-γ)were detected by ELISA(enzyme-linked immuno sorbent assay).Results:Mature DCs presented typically morphological and phenotypic features;the DCs in Lysate + pJAK2-DCs group had the highest expression levels of CD80,CD83,CD86 and HLA-DR(human leukocyte antigen DR).When the ratio of effectors to target cells ranged from 10:1 to 30:1,the killing activity of CTLs had a positive correlation with the ratio.When the ratio of effectors to target cells was 30:1,the killing activity of CTLs in the control group was(19.77±2.34)%,which was lowest as compared with the other groups(P < 0.01),meanwhile the killing activity of CTLs in Lysate + pJAK2-DCs group was higher than those in Lysate-DCs and pJAK2-DCs groups(P < 0.05).The levels of IL-12 and IFN-γ secretion in Lysate + pJAK2-DCs group were apparently higher than those in the control group(P < 0.01).Conclusion:An antagonist of SOCS1,pJAK2 polypeptide,can enhance the ability of antigen presentation and specific antitumor effect of DCs on gastric cancer cells.南京军区医学科技创新课题资助项目(编号:10MA068); 福建省自然科学基金面上项目(编号:2010D013); 厦门市科技计划创新项目(编号:3502z20104014

一种浮动复合型人工鱼巢

一种浮动复合型人工鱼巢，包括浮动框架，在浮动框架的四周设有多个固定装置，并且浮动框架与固定装置之间是采用活动连接，在浮动框架上分布设有多根缆绳，在缆绳的端部固接有沉子，在沉子与浮动框架之间的缆绳上固定连接多个粘附基质，本实用新型提供一种能为产粘性卵鱼类提供产卵场所的浮动复合型人工鱼巢，能有效促进鱼类资源的保护和可持续利用。</p

Effect of Helicobacter pylori on the function of peripheral blood monocyte-derived dendritic cells in gastric cancer patients

分析HP阳性和HP阴性的胃癌患者外周血单核细胞来源树突状细胞(MOdCS)功能的差异性及其临床意义。方法:用尿素14C呼气试验对解放军第一七四医院2011年1月至2012年10月收治的84例胃癌患者进行HP感染状态鉴定,分别采集HP阳性和阴性胃癌患者外周血,分离外周血单个核细胞,采用经典方法(rHgM-CSf、rHIl-4联合rHTnf-α)诱导产生dCS,采用流式细胞仪检测dCS表型,采用ldH释放法检测dCS致敏T细胞对胃癌细胞的毒性杀伤作用,采用ElISA方法检测细胞因子Il-12、Ifn-γ的分泌水平。结果:两组MOdCS成熟过程形态变化无差异,HP阳性组MOdCS表面标记分子Cd1A、Cd80、Cd83、Cd86和HlA-dr平均表达百分率均高于HP阴性组,其中Cd80、Cd83、Cd86的表达水平差异有统计学意义,Cd1A、HlA-dr差异无统计学意义。HP阳性组dCS致敏T淋巴细胞对胃癌细胞杀伤率和Il-12、Ifn-γ的分泌水平均高于HP阴性组(P<0.05)。结论:HP感染状态不影响胃癌患者外周血MOdCS成熟过程形态变化,HP感染的胃癌患者MOdCS成熟和活化水平更高。Objective:This study aimed to compare and analyze the functional differences between peripheral blood monocyte-derived dendritic cells(DCs) of Helicobacter pylori-positive and H.pylori-negative patients with gastric cancer.Methods:H.pylori infection was detected in 84 patients with gastric cancer in our hospital from January 2011 to October 2012 by the14C-urea breath test.DCs were generated from monocytes isolated by an adherent method from the two groups of patients and cultured in the presence of rhIL-4,rhGM-CSF,and rhTNF-α.Furthermore,the expression of surface marker molecules was determined by fluorescence-activated cell sorting analysis.The cytotoxicity of DCs pulsed T cells against gastric carcinoma cell was assessed by the lactate dehydrogenase-releasing assay.The secretion of IL-12 and IFN-γ in the supernatant was determined by enzyme-linked immunosorbent assay.Results:No difference was observed in the morphological change of the maturation process.The mean expression of CD1a,CD80,CD83,CD86,and HLA-DR molecules in DCs of H.pylori-infected patients was higher than that in DCs of H.pylori-negative group,and the differences were statistically significant except for CD1a and HLA-DR.The cytotoxicity activities,IL-12 release,and IFN-γ release in the H.pylori-positive group were significantly higher than those in the H.pylori-negative group(P<0.05).Conclusion:H.pylori infection has no effect on the morphological change of the maturation process of monocyte-derived DCs.These data clearly demonstrate that monocyte-derived DCs of H.pylori-infected patients with gastric cancer can induce stronger maturation and activation than those of H.pylori-negative patients.南京军区医学科技创新课题(编号:10MA068); 福建省自然科学基金资助项目(编号:2010D013); 厦门市科技计划创新项目(编号:3502z20104014)资助~

Zooplanktonic diversity in the western Pacific

西太平洋区是全球海洋生物种源中心,许多类群的最高物种多样性都出现于该区域,因此,在该区开展种类多样性的研究不仅重要和必要,而且具有在跨国尺度上进行综合管理和相互合作的迫切性。本文在西太平洋的浮游动物样品鉴定分类、编目、文献资料整理和分析的基础上,记录和编入西太平洋10个浮游动物类群2,658种(含亚种),隶属于206科675属,其中水螅水母类99科251属697种,栉水母类12科22属59种,浮游软体动物14科35属86种,介形类8科89属416种,桡足类51科156属908种,糠虾类4科58属202种,磷虾类2科8属56种,十足类8科22属105种,毛颚类5科8属48种,被囊类5科26属81种。The western Pacific region has been operating as a centre for the origin of marine biodiversity: the richest diversity of many marine taxa was found in these waters.Therefore,biodiversity research and con-servation efforts in this area are necessary in order to promote the integrative and international management of this resource.The present work is a compilation of numbers of all the families,genera and species of ma-jor taxa of zooplankton known in the western Pacific Ocean(106°–150°E,0°–44°N).In all,2,658 zooplank-tonic species(including subspecies) belonging to 206 families and 675 genera have been recorded from taxonomic identifications and literature,99 families,251 genera and 697 species belong to the Medusozoa,12 families,22 genera and 59 species to the Ctenophora,14 families,35 genera and 86 species to the pelagic Molluscs(Pteropoda and Heteropoda),8 families,89 genera and 416 species to the Ostracoda,51 families,156 genera and 908 species to the Copepoda,4 families,58 genera and 202 species to the Mysidcea,2 fami-lies,8 genera and 56 species to the Euphausiacea,8 families,22 genera and 105 species to the Decapoda,5 families,8 genera and 48 species to the Chaetognatha,5 families,26 genera and 81 species to the Tunicata.908专项“中国海洋生物种类名录和图谱”(908-ZC-II-02)和908专项海洋生物样品库;科技部基础工作专项“我国和邻近西北太平洋海洋生物物种编目和分布图集编制”(2006FY220700

心理所研究生第四党支部召开“党的十九大与我”主题会

1月4日，根据中国科学院心理研究所党委关于开展“党的十九大与我”主题讨论活动的通知要求,心理所研究生第四党支部在南楼五层会议室召开“党的十九大与我”主题讨论会。支部书记李会杰及全体学生党员共15人出席会议。 会议首先由李会杰主持进行“党的十九大与我”主题讨论。大家结合党的十九大的主要精神与自身的科研生活，以党小组为单位，进行广泛而深入的讨论。每个党小组推选一位代表，总结了小组对于十九大的感想。研究生第三团支部的李才文和励奇添也作为团员代表发表了自己的感想。 接着支部共同讨论了刘文娟和张倩的转正问题。通过集体投票表决，全票通过了两位预备党员的转正申请，接收其成为中国共产党正式党员。 第三项活动是支部创新活动，参会人员首先观看了党史纪录片《重生》。这是一部全面展示自1921年建党至1949年建国，二十八年历程的纪录片，文献价值丰富，并且制作精良，人物鲜活且细节丰富，为支部党员更深刻地学习感受党的历史，理解党的决策方针提供了良好的媒介。 接下来，支部还讨论了“两学一做问卷调研”活动的安排。支部党员结合自身专业优势，就具体成效和体会，以结构化问卷方式进行反馈，致力于将“两学一做”做到常态化制度化。根据本支部自身情况，将15名党员分为若干个党小组，在小组内部组织结构化访谈，将结果整理后，在支部会议上与其他党小组进行交流。这种方式有利于支部内部对两学一做以及重要讲话的学习成果进行考察和监督。会上共同研讨了问卷调研的具体内容，计划在随后的几周内完成。 最后支部策划并动员大家参与户外体验活动。户外活动既是党员之间加强交流和沟通的一个渠道，也是党员深入实际了解民情民意的一个契机，更是对“做合格党员”的一次践行。支部计划去养老院看望孤寡老人，发挥专业特长解决心理上的困扰，同时发挥认知科学实验室学生支部特色，对有需要的老人进行认知功能测查，以便后续进行预防和干预。 李会杰对本次支部会议进行总结，他对大家在支部活动中表现出的良好精神面貌、强烈的责任感和使命感表示赞赏，希望大家继续努力，为实验室和研究所的发展做出更多的贡献

研究生第四党支部召开年度述职评议和党章学习会

1月15日下午，研究生第四党支部在南楼5层会议室召开年度支部书记述职会，并集体学习《习近平谈治国理政》第二卷和新党章。党支部书记李会杰及支部党员共16人出席会议。 会议第一项内容是支部书记述职。支部书记李会杰向与会党员汇报了一年来的工作。李会杰从主要工作回顾、主要成效、工作特色与创新点以及存在的问题及改进措施四个方面，总结概括了2017年的工作情况。听完述职报告，大家表示这一年支部书记带领支部取得了很大进步，支部党员参加支部的各种学习活动和社会活动的积极性得到了很大提升，党支部的凝聚力也得到了进一步的加强。之后，在支委叶玉婷的组织下，大家对支部书记的现场述职进行了民主评议。根据评议统计结果，全体党员对党支部书记的最终评议结果为“好”，充分证明支部党员对一年来支部活动的认可。李会杰也对支部党员一年来的参与配合表示肯定，希望大家继续努力，为支部发展做出更大贡献。 会议第二项活动是集体学习《习近平谈治国理政》第二卷。三个党小组分别选派一人带领大家学习这本书的一个部分。来自三个党小组的张秀平，程南华，张蕾，分别从廉政建设、从严治党以及建设美丽中国三个方面，带领大家学习了这本书。通过此次学习，各位党员加深了对治国方针的理解，强化了作为一名党员对于自身的更高要求。 会议最后一项活动是学习新党章，由副书记陈宁轩带领大家学习。支部党员通过朗读的方式，重点学习了党章中增补或新修改的内容。李会杰也对重要的党章修改部分进行了评议，加深大家对新党章的理解。 最后，李会杰对本次支部活动进行了总结，在肯定本次学习活动的同时，也对大家今年的学习活动中提出了新要求，希望大家再接再厉，不忘初心，在科研学习和支部活动中砥砺前行