11 research outputs found

    Design of Automatic System for Measuring Dielectric Properties of Microwave Dielectric Ceramics

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    开路型微波陶瓷材料介电性能自动测试系统的设计包括系统的测试原理、系统硬件和软件组成。利用操作界面友好的自动测试程序,可在程序面板上控制网络分析仪,实现测试数据的实时采集、分析计算与显示存储,从而提高测试效率与精度。实测表明,利用该系统能对高介电常数、低损耗的微波陶瓷材料复介电常数进行快速、准确、无损的自动测试。Design of open automatic system for measuring dielectric properties of Microwave Dielectric Ceramics(MWDC) is introduced,including testing principle,system hardware and software.The automatic measurement program provids a friendly interface between the VNA and the experiment operators,it can be applied to control the network analyzer,sample and compute the testing data,the results can be obtained and saved instantly.the measurement efficiency and precision are improved.It is shown that the system can be used for the rapid,accurate,nondestructive and automatic measurement of the high εr′ and low tan δ of MWDC materials

    丝组二肽——现代蛋白酶分子进化过程中的原始雏形

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    系统阐述了我们实验室近十五年来对丝组二肽的生物活性的研究.丝组二肽是目前报道的具有多种切割活性的最小活性肽,它不仅能够切割DNA,而且可以切割蛋白质及羧酸酯.丝组二肽是迷你的磷酸酯酶和蛋白水解酶,是现代蛋白酶分子进化过程中的原始雏形

    肝脏局灶性结节性增生1例

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    患者,男性,37岁,因"乏力、纳差、尿黄、右胁部闷痫不适1月余"入院。查体:生命体征平稳,神清,表情轻度痛苦,无贫血貌,全身皮肤、巩膜无黄染,无皮疹、出血点及瘀斑,胸前皮肤有蜘蛛痣,未见肝掌。浅表淋巴结未触及。面色无晦暗,颈软,心肺无明显异常发现。腹部不平,右上腹轻度隆起,未见腹壁静脉曲张,腹肌软,右上腹压痛,无反跳痛,肝肋下2.3 cm,质

    THE EFFECTS OF LOW DOSE MORPHINE ON LOCOMOTOR ACTIVITIES IN RATS

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    腹腔注射不同剂量吗啡(8,4,2,1mg/kg/day),观察各组大鼠在给药后不同时间内的活动性(locomotoractivity,LA)。连续给药8天,每天给药后95min内,每间隔15min,记录大鼠5min内在限定空间中所走格数。结果表明:随吗啡给药剂量或次数增加,LA呈升高趋势;使大鼠LA明显兴奋的适宜低剂量为4mg/kg/day,该剂量下每天给药后15-20minLA为峰值,而且此时段LA逐日升高,至第8日出现下降趋势。此结果在一定程度上动态地揭示了吗啡剂量、作用时间及其运动效应之间的相互关系。</p

    小剂量吗啡对大鼠活动性的影响

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    腹腔注射不同剂量吗啡,观察各组大鼠在给药后不同时间的活动性(locomotoractivity,LA),连续给药8天,每天给药后95min内,每间隔15min,记录大鼠5min内在限定空间中所走格数。结果表明:随吗啡给药剂量或次数增加,LA呈升高趋势;使大鼠LA明显兴夯的适宜低剂量为4mg/kg/day,该剂量下每天药后15-20minLA为峰值,而且此时段LA逐日升高,至第8日出现下降趋势,此

    高效液相色谱法定量测定美氟尼酮(吡非尼酮的新衍生物)的浓度及其在肝微粒体中的初始药代动力学研究(英文)

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    本研究开发了一种简单可靠的HPLC-UV方法用于美氟尼酮的测定。生物分析步骤包括从500μL肝微粒体系统中通过甲醇沉淀蛋白质提取美氟尼酮。色谱条件:色谱柱为Agilent TC-C18柱(4.6 mm×250 mm,5μm),流动相为10 mM甲酸铵(用10%的甲酸调PH至2.9)–乙腈(70:30,v/v),流速为1.0 mL/min,UV检测波长设定在245 nm。美氟尼酮和吡非尼酮(内标物)分别在6.0和9.7分钟洗脱,总运行时间为12分钟。根据美国食品和药物管理局生物分析指南,进行了方法验证,结果符合验收标准。美氟尼酮在肝微粒体中的标准曲线在0.5–16μg/mL范围内呈线性关系。美氟尼酮内和外间精确度低于9.0%,偏差在±10.0%以内。美氟尼酮在肝微粒体中孵育后,该方法成功应用于药代动力学研究。The National Natural Science Foundation of China(Grant No.81302819),the National Natural Science Foundation of China(Grant No.C0709-31201056);;the Fundamental Research Funds for the Central Universities of China(Grant No.7601110179);;the Fundamental Research Funds for the Central south Universit..

    JUNO Sensitivity on Proton Decay pνˉK+p\to \bar\nu K^+ Searches

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    The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in pνˉK+p\to \bar\nu K^+ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via pνˉK+p\to \bar\nu K^+ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is 9.6×10339.6 \times 10^{33} years, competitive with the current best limits on the proton lifetime in this channel

    JUNO sensitivity on proton decay pνK+p → νK^{+} searches

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