Design and Implementation of Power Quality Analyzing System

随着科学技术和国民经济的快速发展，各种工业生产对电力系统电能质量的要求越来越高。然而，现代电力电子设备和非线性负载的大量使用又造成电能污染日趋严重，电能质量成为电力部门及其用户日益关注的问题。 本文首先分析了电能质量问题的产生和国内外关于电能质量分析软件的发展情况，以及有关电能质量的定义和术语的标准化问题。详细描述了我国关于电能质量的六项标准中指标的定义及相关限值：电压偏差、频率偏差、公网谐波、电压波动和闪变、三相电压不平衡及暂态过电压和瞬态过电压，并结合国标和受关注的暂态事件提出本系统使用到的指标。 然后，提出了分布式电能质量实时监测与分析系统的思路和总体方案，并在该方案的前提下设计了服...With the rapid development of science and technology and the national economy, the demand for high-quality electric power in industrial production is growing. However, the use of modern electronic equipment and nonlinear load made the power increasingly serious polluted, power quality has been more and more concerned to the electricity sectors and its customers. Firstly, from the development pro...学位：工学硕士院系专业：信息科学与技术学院计算机科学系_计算机系统结构学号：2302006115241

全反式视黄酸体外处理胃癌细胞对其裸小鼠皮下移植瘤的影响

用全反式视黄酸（ＡＴＲＡ）处理３株胃癌细胞株ＭＧｃ８０３、ＢＧＣ８２３和ＳＧＣ７９０１（ＡＴＲＡ终浓度为１０－６ｍｏｌ／Ｌ）连续２０ｄ，再移植于６～８周龄的ＢＡＬＢ／ｃ裸小鼠后肢皮下，观察移植瘤生长情况，４周后处死裸小鼠，解剖肿瘤并行组织学检查。结果表明，ＡＴＲＡ体外处理胃癌细胞能延长其移植瘤的潜伏期和倍增时间，有效地抑制移植瘤的生长，抑制率分别为５１．４％、６６．０％和８８．６％，抑制作用的强弱次序与移植瘤的恶性程度正好相反

Effects of all trans relinoic acid on the liver metastatic model of gastric cancer cells, BGC-823 and MKN-45

目的　研究全反式视黄酸 (ATRA)对胃癌细胞实验性肝转移能力的影响。方法　将胃癌细胞BGC 82 3和MKN 45注射于裸小鼠脾包膜下 ,隔日给裸小鼠灌服ATRA。术后 6周处死裸小鼠 ,解剖脾脏及肝脏肿瘤并用免疫组织化学方法测定其肿瘤血管密度 ;以放射免疫法测定血清癌胚抗原 (CEA)。结果　ATRA抑制胃癌细胞脾包膜下移植瘤的生长及其肝转移 ,抑制率分别为 5 0 .0 %(BGC 82 3)和 33.3% (MKN 45 ) ;使脾移植瘤和肝转移瘤的肿瘤血管密度降低。ATRA还可使肝转移模型鼠血清CEA含量分别下降 5 0 .2 4% (BCG 82 3)和 48.10 % (MKN 45 )。结论　ATRA能有效抑制胃癌细胞的实验性肝转移 ,从而抑制胃癌细胞分泌CEA以及抑制肿瘤血管的形成。 【英文摘要】 Objective To investigate the effects of all trans retinoic acid (ATRA) on experimental liver metastatic ability of gastric cancer cells. Methods BGC 823 and MKN 45 cells were injected into spleen subcapsule of nude mice, who were administrated ATRA every other day after operation. Six weeks after operation, the nude mice were executed. Tumors in spleen and liver were examined pathologically and microtumor vessel density (MVD) was measured by using immunohistochemical method and serum carcino embryonic ..

视黄酸对胃癌细胞的诱导分化及其相关酶活性的影响

目的研究视黄酸对胃癌细胞的诱导分化及其相关酶活性的影响。方法１０－６ｍｏｌ／Ｌ的全反式视黄酸（ＡＴＲＡ）处理胃癌细胞株ＢＧＣ８２３和ＭＫＮ４５，用流式细胞术检测细胞周期的分布，以酶标仪测定相关分化标志酶的活性，用３ＨＴｄＲ掺入法测定ＤＮＡ合成速度和ＭＴＴ法检测细胞的生长。结果ＡＴＲＡ使ＢＧＣ８２３细胞出现Ｇ０／Ｇ１期停滞，分化标志酶ＬＤＨ、ＡＬＰ和βＧ的活性下降，抑制率分别为２２４％，３２９４％和４１３５％，使ＤＮＡ合成速率下降４１４３％，生长抑制率为６１０３％；但不能改变ＭＫＮ４５细胞的上述指标。结论ＡＴＲＡ能诱导ＢＧＣ８２３细胞分化并抑制其恶性生长，对ＭＫＮ４５细胞则没有这种作用

视黄酸对胃癌细胞生长和p53及c-myc基因表达的影响

目的：探讨视黄酸对胃癌细胞生长和基因表达的影响。方法：以ＭＴＴ法测定细胞生长，软琼脂集落形成实验测定癌细胞恶性程度，Ｎｏｒｔｈｅｒｎｂｌｏｔ测定ｐ５３及ｃｍｙｃ基因表达水平。结果：１０－６ｍｏｌ／Ｌ全反式视黄酸（ＡＴＲＡ）能够有效地抑制ＭＧｃ８０３和ＢＧＣ８２３细胞生长，但不能抑制ＭＫＮ４５细胞生长；ＡＴＲＡ还能够降低３株胃癌细胞形成集落的能力。ＭＧｃ８０３和ＢＧＣ８２３细胞经ＡＴＲＡ诱导后，ｐ５３基因的表达水平提高，ｃｍｙｃ基因的表达水平下降，但ＭＫＮ４５细胞中ｐ５３基因和ｃｍｙｃ基因表达与ＡＴＲＡ诱导无关。视黄酸受体ＲＡＲα基因在３株细胞中呈低水平表达，经ＡＴＲＡ诱导后，在ＭＧｃ８０３和ＢＧＣ８２３细胞中表达水平提高，但在ＭＫＮ４５细胞中表达水平不变。结论：ＡＴＲＡ诱导ＲＡＲα高水平表达可能与视黄酸抑制胃癌细胞生长和调节ｐ５３和ｃｍｙｃ基因表达有

视黄酸对胃癌细胞恶性表型的影响

研究ｔ－ＲＡ对胃癌细胞的作用和探讨其作用机理．结果表明：１）ｔ－ＲＡ能够有效地抑制胃癌细胞的生长．２）ｔ－ＲＡ能够降低胃癌细胞在软琼脂中形成集落的能力．３）ｔ－ＲＡ能够降低胃癌细胞的粘附能力．４）ｔ－ＲＡ能够抑制胃癌细胞在裸鼠中形成肿瘤的能力．４）扫描电镜观察显示，经ｔ－ＲＡ处理后，胃癌细胞表面的微绒毛消失．以上结果表明，ｔ－ＲＡ对胃癌细胞的恶性表型有显著的抑制作用．ｔ－ＲＡ可能作为治疗胃癌的有效药物

Design and Realization of Power Quality Analyzing System

为实现对电能质量实时监测与管理,提高电力企业信息化水平,综合国内外多种电能质量评估系统的性能,文中设计并研发了一种电能质量在线分析管理系统,实现了电能质量评估工作的系统化、实时化,提高电力企业信息化水平,并为电能质量的控制奠定了基础。该系统基于.nET平台构建开发,分为表示层、业务逻辑层及数据管理层对代码进行优化管理。采用AdO.nET技术,通过统一的数据库管理数据,实现了系统管理、电能质量在线分析及自定义生成报表等功能。该系统具有多指标分析的完善性、自定义生成报表的灵活性、使用方便、界面友好等特点。In order to achieve real-time supervision and management of power quality,enhance informationize level of power enterprises,synthesized the performance of many kinds of energy quality appraisal system on home and abroad,designed and developed one kind of power quality on-line analyzing management system.It realized systematization and timeliness of power quality evaluation work,enhanced informational level of power enterprises,and lay the foundation for power quality controlling.Fundamentally based on the.NET platform,meanwhile it was divided into the presentation level,the business logic level and the data management level,and realized the optimized management to the code.Adopting the ADO.NET technology and unifying database for data management,realized functions such as system administration,power quality online analyzing and custom report generating.The system has characteristics of perfection in multi-index analyzing,flexibility in custom report generating,easy to maintain and user friendly

Growth inhibition of gastric cancer cells by all-trans retinoic acid through arresting cell cycle progression

目的　探讨ATRA调节胃癌细胞生长的作用机理。方法　Westernblot测定蛋白表达水平 ,免疫沉淀测定蛋白激酶活性 ,MTT方法检测细胞生长和流式细胞术分析细胞周期。结果　ATRA有效地诱导细胞滞留G0 /G1期并抑制胃癌细胞生长。ATRA通过依赖P5 3和非依赖P5 3途径诱导ATRA敏感细胞的P2 1WAF1/CIP1表达 ,由此导致CDK4 和CDK2 活性下降 ,但对CDK4 和CDK2 蛋白表达没有影响。另外 ,由于ATRA抑制CDK4 和CDK2 活性 ,导致Rb蛋白去磷酸化水平上升。结论　ATRA通过调节细胞周期进程的相关蛋白而抑制胃癌细胞生长。 【英文摘要】 To investigate the mechanism of all trans retinoic acid (ATRA) on the regulation of the cell cycle in gastric cancer cells Methods The protein level was detected by Western blot Immunoprecipitation was used in protein kinase activity determination Cell growth and cell cycle phase were examined by MTT assay and flow cytometric analysis, respectively Results ATRA could effectively induce G 0/G 1 arrest and inhibit cell growth in certain human gastric cancer cell lines ATRA might induce p21 W...This work was supported by the National Outstanding Youth Science Foundation of China (B type, No.39825502) and the National Natural Science Foundation of China (No. 39880015