Quanzhou Port of Oversea Trade Research Review In Song Yuan Ming Dynasty

泉州港的研究源于上世纪二十年代，七十年代后随着水下考古的发展，泉州港研究取得较大突破。目前泉州港的研究成果极为丰富，但存在着量多质劣的问题，因此将前人成果作适当总结，以展望未来研究方向是十分必要的。本文根据目前研究情况，分三个主题梳理前人研究成果，分别是港口兴衰历程、贸易方式、海商华侨。 就第一个主题而言，包括港口兴衰的原因、商品的海外销售。从目前研究成果来看，对泉州港兴起与衰落的原因并无定论，但越来越多学者注意到国际贸易大环境对泉州港的冲击。研究方法上，开始将泉州港置于印度洋贸易圈乃至世界贸易网络中进行讨论。 至于第二个主题，本文主要安排市舶贸易与朝贡贸易，其中以市舶贸易与国家财政之间的...In the 1920s, scholars begin studied the port of Quanzhou. In the 1970s, with the development of underwater Archaeology, the port of Quanzhou had breakthrough in research. Now, the research of quanzhou port is rather rich, so we summarize the research to find out the new research fields.There are three part in this article, including the history of Quanzhou port, the way of trade , businessman and...学位：历史学硕士院系专业：人文学院_专门史学号：1032011115215

华南与东南亚华人社会的互动关系--以潮人侨批网络为中心 (1911-1949) = Interactions between South China and the Chinese Communities in Southeast Asia : A study of the Teochew remittance networks, 1911-1949

Ph.DDOCTOR OF PHILOSOPH

Study on the Policy Operation Mode of China's Export Credit Insurance

在经济全球化和一体化的形势下，国际贸易竞争日趋激烈。出口信用保险由于其在促进对外贸易和投资方面的重要作用而成为各国普遍采用的政策性工具。随着我国出口信用保险业务的发展和政策性运营模式的不断成熟，特别是WTO过渡期的结束，出口信用保险在促进对外经贸方面的作用将更加明显。在此背景下，有必要在对出口信用保险运营进行政策性分析的基础上，通过借鉴发达国家的先进经验，从理论和实践方面深入分析我国出口信用保险政策性运营模式在运作中存在的问题，并针对这些问题，从宏观层面设计出口信用保险运营的模式体系，为我国政府支持、指导、监督出口信用保险的健康快速发展提供一些政策建议。本文在参考相关研究文献的基础上，分四章论...In the situations of globalization and integration, the international trade competition becomes more and more intense. For the important functions of accelerating foreign trades and investments, the Export Credit Insurance (ECI) is popularized as a pervasive policy tool in many countries. Along with the growing up of the operations of ECI and the policy operation mode, especially after the ending ...学位：经济学硕士院系专业：经济学院财政金融系_金融学(含保险学)学号：20044202

Research of Establishing SK Company’s Process Organization

上世纪90年代以来，我国软件产业蓬勃发展，为软件企业创造了千载难逢的发展机遇，2002年5月厦门SK软件开发有限公司（以下简称SK公司）应运而生。进入21世纪，软件业的竞争尤为激烈，软件行业的变化因为其所服务的客户企业的变化而变化，能够顺应客户企业变化的软件企业获得了生存，而那些无法根据市场环境做自我调整的软件企业将逐渐退出软件行业舞台。SK公司经历了一段快速发展的阶段，在这个阶段中SK公司全力致力于市场的开拓，而忽视了内部的管理。随着企业人员的增多，管理的难度与复杂性加大，SK公司要想在竞争中立于不败的地位，除了提供好的产品外，通过流程再造，提升内部管理能力，提高企业的核心竞争力成了SK公司...Thousands of software companies have sprung up thanks to the progressing prosperity of the software industry in China since 1990’s. Xiamen SK Software R&D Co., Ltd. (known as SK Company as follows), established in May 2002, is one of them. The software industry faces fierce competition after marching into the 21st century. The changes within the software industry become frequent due to the cha...学位：工商管理硕士院系专业：管理学院工商管理教育中心_工商管理硕士(MBA)学号：20031503

O2和CO在Ni（111）表面的吸附活化

采用高分辨电子能量损失谱（HREELS）、俄歇电子能谱（AES）和低能电子衍射（LEED）研究镍单晶表面氧物种及CO与O2的共吸附。实验结果表明,Ni（111）表面氧化后存在两种氧物种,位于54me V能量损失峰的表面化学吸附氧物种和位于69 meV能量损失峰的表面氧化镍。首先,随着暴露氧量的增加,表面化学吸附氧物种的能量损失峰蓝移至58 meV;其次,通过真空退火及与CO相互作用考察,发现表面化学吸附氧物种较不稳定。在室温条件下,表面预吸附形成的表面化学吸附氧物种与CO共吸附,导致端位吸附CO增多,表明氧优先吸附在穴位上,随着CO暴露量的增加化学吸附氧物种与CO反应脱去;而表面氧化镍需在较高温度和较高CO分压下才能被CO还原。预吸附CO可被氧逐渐移去。国家自然科学基金(21273178,21573180,91545204)资助项目~

NRP- 1 monoclonal antibody in combination with metronomic chemotherapy (MCT) inhibits the growth of gastric cancer xenografts in nude mice

目的:探讨NRP-1单抗联合多西他赛节律化疗对胃癌裸鼠移植瘤的抗肿瘤疗效。方法:BALB/c裸鼠皮下接种胃癌BGC-823细胞制备移植瘤模型,将; 荷瘤裸鼠以数字随机表法随机分为对照组、NRP-1单抗组、节律化疗组(MCT)、联合组(NRP-; 1mAb+MCT),每组6只。除对照组,其余各组于造模第8天开始分别给予相应治疗,给药2周,观察裸鼠一般状况,隔天测量裸鼠体重及肿瘤体积。裸鼠处; 死后称瘤质量,H-E染色观察瘤组织形态,免疫组化检测裸鼠瘤组织中NRP-1蛋白、VEGF、MVD表达。结果:联合组移植瘤的体积和质量显著低于其他; 各组[ (0.3940.128)vs(0.7480.152)、(0.8670.361)、(1.2470.494) g;(0.6130.223); vs (0.8660.115)、(1.0980.343)、(1.4740.644); cm~3。均P<0.05],抑瘤率较其他治疗组差异有统计学意义(P<0.05)。对照组癌组织细胞生长良好,血管丰富,给药组癌组织出现不同程度的片; 状坏死,血管成分减少。免疫组化染色显示,对照组NRP-1表达明显高于治疗各组(P<0.05),联合组的NRP-1、VEGF、MVD表达均显著低于; 其余各组(P<0.05)。结论:NRP-1单抗联合多西他赛节律化疗可能通过下调NRP-1表达而显著抑制BGC-823胃癌移植瘤的生长及血管生成。Objective: To investigate the antitumor effect of NRP-1 monoclonal; antibody combined with docetaxel metronomic chemotherapy in nude mice; bearing gastric cancer xenografts. Methods: BALB / c mice were; inoculated subcutaneously with BGC-823 cells to establish xenograft; model; the tumor bearing rats were randomly divided into control group,; NRP-1 monoclonal antibody group (NRP-1mAb), rhythm chemotherapy group; (MCT) and combined group (NRP-1mAb+MCT). Except the control group, the; other three groups were given the corresponding treatment on the 8th day; after the model establishment. After 2 weeks of administration, the; general condition of nude mice was observed and the body weight and; tumor volume were measured the next day. The mice were sacrificed and; the mass of tumor was calculated; HE staining was used to observe the; morphology of the tumor tissue. The expression of NRP-1 protein, VEGF; and MVD were detected by immunohistochemistry. Results: The tumor volume; (0.6130.223 vs 0.8660.115, 1.0980.343, 1.4740.644 V/cm~3; P<0.05) and; weight (0.3940.128 vs 0.748 0.152, 0.8670.361, 1.2470.494 m/g; P<0.05); of the combined group were significantly lower than those of the other; groups, and the tumor inhibition rate was statistically higher compared; with the other treatment groups (P< 0.05). Under microscope, the cancer; cells in the control group were well grown and the blood vessels were; rich; the cancerous tissues of each treatment group showed different; degree of sheet necrosis and the blood vessel composition decreased.; Immunohistochemistry results showed that the expression of NRP-1 in the; control group was significantly higher than that in each treatment group; (P<0.05); and the expression of NRP-1, VEGF and MVD in combined; treatment group was significantly lower than the other groups.; Conclusion: NRP-1 monoclonal antibody combined with docetaxel rhythmic; chemotherapy may significantly inhibit the growth and angiogenesis of; BGC-823 gastric cancer by down-regulating the expression of NRP-1.厦门市科技计划创新项目资

Inhibitory effect of NRP-1mAb on the growth of gastric cancer cell BGC-823

目的观察自主研发的抗NRP-1b1/b2IgG单克隆抗体（NRP-1mAb）对胃癌BGC-823细胞生长的影响,并初步探讨可能的作用机制。方法实验室制备NRP-1mAb,采用SDS-PAGE检测纯度。采用0、25、100、200、400μg/ml NRP-1mAb培养胃癌BGC-823细胞,光学显微镜下观察细胞形态学变化;采用MTT法、集落形成实验、流式细胞术观察胃癌细胞BGC-823的增殖、集落形成和凋亡的情况;Western blotting法检测NRP-1mAb作用后Akt、p38、ERK、JNK信号蛋白磷酸化情况。结果SDS-PAGE检测显示,NRP-1mAb的纯度在95%以上。光学显微镜观察显示,NRP-1mAb作用后,BGC-823细胞形态呈凋亡改变。MTT实验显示,NRP-1mAb抑制BGC-823细胞的增殖作用呈浓度和时间依赖性（P〈0.01）。集落形成实验显示,不同浓度NRP-1mAb均能显著抑制BGC-823细胞的集落形成,其抑制率呈浓度依赖性（P〈0.01）。流式细胞术检测显示,不同浓度NRP-1mAb均明显促进BGC-823细胞凋亡,且大部分集中在早期凋亡。Western blotting检测显示,BGC-823细胞的Akt磷酸化受到抑制,ERK、p38、JNK的磷酸化水平无明显变化。结论NRP-1mAb能抑制胃癌细胞BGC-823的生长、促进凋亡,可能与抑制Akt磷酸化有关。Objective To observe the effect of NRP-1b1/b2 IgG monoclonal antibody（ NRP-1） on the growth of gastric cancer cell BGC-823,and to explore the possible mechanism of the antibody. Methods NRP-1mAb was prepared in laboratory,and the purity of antibody was detected by SDS-PAGE. Gastric cancer BGC-823 cells were cultured by 0,25,100,200,400 μg/ml NRP-1 mAb. The morphological changes of BGC-823 cells were observed by microscope. The proliferation,colony formation and apoptosis of gastric cancer BGC-823 cells were observed by MTT assay,colony forming assay and flow cytometry. The phosphorylation of related signal proteins was detected by Western blotting analysis. Results SDS-PAGE test showed that the purity of NRP-1mAb was above95%. Microscopy showed apoptotic changes of BGC-823 cells treated by NRP-1mAb. MTT assay showed that NRP-1mAb could inhibit the proliferation of BGC-823 cells in a time and dose dependent manner（ P〈0. 01）. Colony forming assay showed that different doses of NRP-1mAb could inhibit the colony formation of BGC-823 cells in a dose dependent manner（ P〈0. 01）. Flow cytometry showed that different doses of NRP-1mAb could promote the apoptosis of BGC-823 cells mainly at early apoptosis stage. It was found that the level of Akt phosphorylation was decreased after treated by NRP-1mAb,and there was no significant phosphorylation of ERK,p38 and JNK protein. Conclusion NRP-1mAb can inhibit the growth of gastric cancer cell BGC-823 and promote apoptosis,which may be related to the inhibition of Akt phosphorylation.厦门市科技计划创新资助项目（3502z20134026,3502z20144034

Progress of C_2-Symmetric Biphenyl Bisphosphine Ligands Ⅲ

手性膦配体的合成及其在手性诱导催化反应中的应用一直是不对称合成与催化研究中非常重要的研究领域之一。近10年来,大量的C2-轴对称手性双膦配体被合成出来并成功地应用于不对称催化研究,本文从C2-轴对称联苯类手性双膦配体的介绍、合成方法、C2-轴对称联苯类手性双膦配体在不对称催化氢化、以及其在其他不对称诱导反应中的应用4个方面综述了相关研究进展,并对今后配体的合成及应用前景进行了展望。A vast number of biphenyl atropisomeric diphosphine ligands are successfully applied in asymmetric catalysis.The synthesis and applications of this type of ligands are a continuous interesting theme in organic chemistry.This review describes recent progress in synthesis and application of C2-Symmetric diphosphine ligands on the asymmetric catalysis hydrogenation and other asymmetric induced reaction,and the future ligand synthesis and application prospect.国家自然科学基金(20272037); 教育部博士点基金(20080610022); 四川自然科学基金重点项目(07ZA109

Study on the Nutrient Content of Bamboo Leaves and Soil in Coastal Region of Fujian

第一作者简介：陈松河，男， 1968年出生，福建长泰人，研究员，硕士生导师，硕士，主要从事园林植物（竹类）分类、栽培与抗逆性研究。通信地址： 361003厦门市思明区虎园路 25号， Tel：0592-2039619，E-mail：[email protected]。[中文文摘]为了研究福建滨海地区竹类叶片与土壤养分状况,对福建滨海3地厦门园博苑百竹园、莆田赤港华侨农场竹园和莆田湄洲岛竹类植物叶片和土壤养分进行实地调查取样分析。结果表明:3地17种竹类成熟叶片和衰老叶片氮(N)、磷(P)含量存在显著差异,且存在明显的地域性差异;竹类生长土壤氮(N)含量均值大小依次为厦门园博苑0.3697mg/g、莆田赤港0.2820mg/g、莆田湄洲岛0.1921mg/g;磷(P)含量均值大小依次为莆田湄洲岛0.3926mg/g、厦门园博苑0.3134mg/g、莆田赤港0.2152mg/g;莆田赤港和莆田湄洲岛10种竹类成熟叶片叶绿素a含量(Ca)和叶绿素b含量(Cb)均值比达到2.17,Ca和Cb间经11种单因子模型拟合,最优的拟合方程为:YA=0.9699+3.7374B-0.7166B2+0.0439B(3A代表Ca,B代表Cb),相关系数的平方达0.934,呈极显著相关关系;竹类植物盐害等级为0级的有5种,盐害等级为1级的有10种,盐害等级为2级的有2种,盐害等级为3级以上的未见。[英文文摘]In order to study nutrient status in bamboo leaves and soil,3 coastal region in Fujian, Xiamen Garden & Flower Expo (XMYB), Farm for Returned Overseas Chinese in Putian (PTCG) and Meizhou Island of Putian (PTMZ) were studied in this paper by field investigation and sampling analysis. The results were shown as follows: the content N and content P in mature and senescent of 17 species leaves in 3 coastal region were significant difference, also significant difference in region. The average value content N of bamboo soil inXMYB, PTCG, PTMZ were 0.3697, 0.2820, 0.1921 mg/g in turn. The average value content P of bamboo soil inPTMZ, XMYB, PTCG were 0.3926, 0.3134, 0.2152 mg/g in turn. The proportion of 10 mature bamboo speciesaverage value between content Ca and content Cb was 2.17, through 11 models of single factor analysis, the relation between the bamboo’s chlorophyll a content and chlorophyll b content accorded with model cubic: YA= 0.9699 + 3.7374B-0.7166B2 + 0.0439B3 (A stands for content Ca, B stands for content Cb), the square of itscorrelation coefficient was 0.934, it was very significant. Bamboo salt damage 0 degree had 5 species, 1 degreehad 10 species, 2 degree had 2 species, no species in 3-5 degree.厦门市科学技术局科研项目“竹类植物耐盐机理与筛选应用研究”(3502Z20102003);厦门市市政园林局科研项目“竹类植物在观赏园艺上的应用研究”(YK-2000-02

Progress of C_2-Symmetric Biphenyl Bisphosphine LigandsⅡ

手性膦配体的合成及其在手性诱导催化反应中的应用一直是不对称合成与催化研究中非常重要的研究领域之一。近十年来,大量的C2-轴对称手性双膦配体被合成出来并成功地应用于不对称催化研究,本文从C2-轴对称联苯类手性双膦配体的介绍、合成方法、C2-轴对称联苯类手性双膦配体在不对称催化氢化以及其在其他不对称诱导反应中的应用4个方面综述了相关研究进展。A vast number of biphenyl atropisomeric diphosphine ligands have been successfully applied in asymmetric catalysis.The synthesis and applications of this type of ligands are a continuous interesting theme in organic chemistry.This review describes recent progress in synthesis and application of C2-Symmetric diphosphine ligands on the asymmetric catalysis hydrogenation and other asymmetric induced reaction.国家自然科学基金(20272037); 教育部博士点基金(20080610022); 四川自然科学基金重点项目(07ZA109