Development of Compound Semic onductor Wafer and Device Bonding

【中文文摘】半导体晶片直接键合技术已成为半导体工艺的一门重要技术 ,它对实现不同材料器件的准单片集成、光电子器件的性能改善和新型半导体器件的发展起了极大的推动作用。文中详细叙述了近十年来 - 族化合物半导体键合技术的主要实验方法 ,并对各种键合方法的优缺点进行了比较 ,结合自己的工作对化合物半导体的键合机理和界面特性做了总结 ,针对目前的研究工作和应用做了展望 【英文文摘】Semiconductor wa f er direct bonding is a important techniq ue for integrating devices, improving th e performance of optoelectronic devices and making new devices. This paper prese nts the innovative wafer bonding methods of compound semiconductors, analyses th e advantages and disadvantages of variou s mehtods, then discusses the bonding me chanics and the generic nature of the in terfaces. Finally, examples of bonded de vices are presented.国家自然科学基金资助 (项目编号 :60 0 0 60 0 4

FTIR and XPS Analysis of Directly Bonded Si/Si Interface

【中文文摘】通过新颖的键合方法实现了Si/Si直接键合。采用傅里叶红外透射谱(FTIR)对Si/Si键合界面进行了研究,结果表明,高温退火样品的界面组分为Si和O,无OH和H网络存在。X射线光电子谱(XPS)测试结果进一步表明,界面主要为单质Si和SiOx混合网络,且随着退火温度的升高,界面层Si-Si直接成键的密度也越高。 【英文文摘】The Si/Si direct bonding has been achieved by a new bonding technology. Fourier transform infrared spectrum(FTIR) and X-ray photoelectron spectroscopy(XPS) are used to analyze the interface of Si/Si bonding. The results show that there are notinfrared absorbtion peak related to the Si-H bonding and Si-OH bonding in the interface at high temperature, and the interface is consisted of Si and SiO_x. In addition, the research indicates also that the Si/Si bonding density is increased with the increase of bonding temperature

Interface of Si/Si Directly Wafer Bonding

【中文文摘】通过三步直接键合方法实现了 Si/ Si键合。采用 XPS、FTIR、I-V、拉伸强度等手段对 Si/ Si键合结构的界面特性作了深入广泛的研究。研究结果表明 ,高温退火后 ,在键合界面没有 Si-H和 Si-OH网络存在 ,键合界面主要由单质 Si和不定形氧化硅 Si Ox 组成。同时 ,研究还表明 ,I-V特性和键合强度强烈地依赖于退火温度。 【英文文摘】The Si/Si bonding has been achieved by three-step direct wafer bonding technology. Interfacial characteristic has been widely investigated by the X-ray photoelectron spectronscopy (XPS), Fourier transform infrared spectrum (FTIR),I-V and tensile strength. The results show that there are no infrared absorbtion peak related to the Si-H bonding and Si-OH bonding in the interface at high temperature, and the interface is made up of Si and SiO_x. In addition, the researches indicate that both I-V characteristic and bonding energy strongly depend on annealing temperatu re.国家基金 (项目编号 :6 0 0 0 6 0 0 4);; 国家重点基金 (项目编号 :6 0 336 0 1 0 )项目支

Study on the gene expression profile in the bone tissue in primary osteoporosis with kidney-yang deficiency syndrome

目的通过检测原发性骨质疏松症不同中医证型患者骨组织基因表达谱的差异,探讨原发性骨质疏松症肾阳虚证相关基因的信息学特征。方法随机选择原发性骨质疏松; 症患者,中医辨证分型为肾阳虚证组3例,肾阴虚证组3例,无肾虚证组3例,并选择正常骨密度人群3例设为正常对照组。用人全基因组表达谱芯片检测4组人群; 骨组织基因表达谱,筛选共同的差异表达基因,并对这些差异表达基因进行基因通路等相关功能分析。结果肾阳虚证组与正常对照组、肾阴虚证组、无肾虚证组的差; 异表达基因分别为2631条、3976条、6184条;肾阳虚证组与其他3组比较共同的差异表达基因有1037条。这些差异基因参与补体与凝血级联反应、; Hedgehog、TGF-beta、细胞周期等22条信号通路。结论原发性骨质疏松症肾阳虚证的相关基因主要与免疫调节、TGF-beta、细胞周期等; 信号通路相关。Objective To investigate the characteristics of genes expression; profiles of primary osteoporosis with kidney yang deficiency through; analyzing the gene expression difference with gene micro-array. Methods; Patient with osteoporosis were rand omly divided into kidney-yang; deficiency group (n = 3),kidney-yin deficiency group (n = 3),non-kidney; deficiency group (n = 3),according to the syndrome differentiation of; traditional Chinese medicine. Another 3 people with normal BMD were; selected as normal control. Expression profiles of the bone tissue from; 4 groups were detected to screen differentiated expression genes.; Analysis of pathway and other function among these genes was conducted.; Results The number of differentiated expression genes in kidney-yang; deficiency group were 3976,6184,and 2631,compared to kidney-yin; deficiency,non-kidney deficiency,and normal control group,respectively.; The number of common differentially expressed genes were 1037. These; genes were involved in 22 pathways,including complement and coagulation; cascades,Hedgehog signaling pathway,TGF-beta signaling pathway,and cell; cycle. Conclusion Genes related to kidney-yang deficiency syndrome in; primary osteoporosis are mainly related to complement and coagulation; cascades,Hedgehog signaling pathway,TGF-beta signaling pathway,and cell; cycle.福建省科技厅省属公益类科研院所基本科研专项; 福建省自然科学基金项

Breedine and Utilization of New Hybrid Rice Combination Tongyou 039

桐优039是泉州市农业科学研究所与福建神农大丰种业科技有限公司合作用自育的桐A与泉恢039配组而成的三系杂交水稻新品种，于2014年通过福建省品种审定。表现高产稳产、壮秆大穗、熟期转色好等优点。介绍了桐A、泉恢039、桐优039的选育过程，以及桐优039的性状表现、栽培技术和制种技术等。A new three-line hybrid rice combination Tongyou 039 was derived from the CMS line TongA and a restorer line Quanhui 039, developed by Quanzhou institute of agricultural Sciences and Fujian Province Prodigy farm and great harvest seeds Inc., and registered by the Crop Cultivar Registration Committee of Fujian province in 2014. It was characterized by high-yieldin ability, stocky stem and big panicle and good performance in ripe time d so on. This paper introduced breeding procedure of Tong A, Quanhui 039 and Tongyou 039, and main characteristics, cultivation and seed production techniques of Tongyou 039.福建省星火项目（2016S0015）;泉州市科技计划重点项目（2015N27

Study of the gene expression profile in the bone tissue with kidney yin deficiency syndromes in primary osteoporosis

目的通过检测原发性骨质疏松症患者骨组织基因表达谱的差异,探讨原发性骨质疏松症肾阴虚证相关基因的信息学特征。方法随机选择骨质疏松症患者,中医辨证分型为肾阴虚证组3例、肾阳虚证组3例、无肾虚证组3例,并选择正常骨密度人群3例设为正常对照组。用人全基因组表达谱芯片检测4组人群骨组织基因表达谱,筛选共同的差异表达基因,并对这些差异表达基因进行基因通路等相关功能分析。结果肾阴虚证组与正常对照组、肾阳虚证组、无肾虚证组的差异表达基因分别为2378、4026、4071条,肾阴虚证组与其他3组比较共同的差异表达基因有344条,这些差异基因参与免疫调节、矿物质吸收、激素合成、组氨酸代谢等11条信号通路。结论原发性骨质疏松症肾阴虚证的相关基因主要与免疫调节、激素合成、组氨酸代谢、矿物质吸收等信号通路相关。Objective To investigate the characteristics of genes expression profiles of kidney yin deficiency in primary osteoporosis by analyzing the difference of gene expression profiles in the bone tissues in patients w ith primary osteoporosis.Methods Osteoporotic patients were randomly selected.All the patients were divided into kidney yin deficiency group,kidney yang deficiency group,and non-kidney deficiency group according the syndrome differentiation of traditional Chinese medicine.Each group had 3 patients.Another 3 people w ith normal bone mineral density( BMD) w ere selected as normal control.Gene expression profiles of the bone tissues in all 4 groups w ere detected using the human genome-w ide expression profile chip.The differentiated expression genes w ere screened,and the analysis of the related functions of these genes including the pathw ays w as conducted.Results Compared w ith that in kidney yang deficiency group,non-kidney deficiency group,and normal control group,the number of differentiated expression genes in kidney yin deficiency group w as 2378,4026,and 4071,respectively.Compared w ith that in these 3 groups,the number of common differentiated expression gene in kidney yin deficiency group w as344.These genes w ere involved in 11 pathw ays,including immunoregulation,mineral absorption,hormone synthesis,and histidine metabolism.Conclusion Related genes of kidney yin deficiency syndromes in primary osteoporosis are mainly related to the signal pathw ays such as immunoregulation,hormone synthesis,histidine metabolism and mineral absorption.国家自然科学基金(81173280); 福建省科技厅省属公益类科研院所基本科研专项(2011R1038-5); 福建省卫生厅创新课题(2011-CX-30); 福建省卫生厅青年基金项目(2010-1-31

Major causes of death in children less than 5 years of age in Fujian,China,2007-2010

目的分析福建省2007-2010年5岁以下儿童主要死亡原因情况及特征,为制定干预措施提供科学依据。方法 分析死因登记信息网络报告系统上报的福建省2007-2010年5岁以下儿童死因及特征。结果 2007-2010年福建省共报告6 166例5岁以下儿童死亡病例,年平均死亡率为6.28/万,各年龄组即0--岁、1--岁、2--岁、3--岁、4--5岁的死亡率分别为44.89/万、5.48/万、3.28/万、2.38/万、1.76/万。1岁以下占78.74%,1岁以下死亡儿童出生28d内死亡的占64.33%;病例的死亡时间均匀的分布在12个月份,没有明显的高峰时间;死亡地点主要在住院死亡(63.87%),最高诊断依据主要是单纯临床诊断(53.50%),最高级别诊断单位主要是地市级医院(42.96%);前5位的死因分别为围产期疾病、先天异常、伤害、流行性感冒和肺炎、传染病和寄生虫病,合计构成比为69.45%。结论 福建省2007-2010年5岁以下儿童死亡中,以婴儿死亡居多,婴儿死亡中又以新生儿死亡居多。围产期疾病、先天异常、伤害是5岁以下儿童死亡的三大死因。5岁以下儿童死因中先天性异常的比例在逐年上升,循环系统疾病比例在逐年下降。Objective To analyze major causes of death in children under 5 years of age in Fujian,China,and to provide scientific evidence for the protection of infants and young children.Methods The data of 2007-2010 death cases were collected from China Disease Report Information System for children under 5 years of age in Fujian.Microsoft Excel and SPSS 15.0 packages were respectively used to establish the database and to analyze the data.Results A total of 6 166 death cases were reported from 2007 to 2010 for children less than 5 years of age.Death rate was 62.8 /lakh on average.The death rates of children under 1,2,3,4 and 5 years of age were 448.9,54.8,32.8,23.8 and 17.6/lakh,respectively.The number of infant death accounted for 78.74% of cases.64.33% of infant death occurred in newborn babies.There was no seasonal difference for the cases of death.Most cases of death(63.87%) occurred in hospital.The top five causes of death were periparturient diseases,congenital malformations,injuries,influenza and following pneumonia,infectious and parasitic diseases,respectively,together of which accounted for 69.45% of death cases.Conclusion Newborn babies and infants were high risk groups for the death of children under 5 years of age in Fujian.The increasing trend of congenital malformation related death suggests the importance of prenatal screening testing

早熟优质籼稻三系不育系伍天A的选育

【目的】选育早熟优质三系不育系,为优质稻新品种选育奠定基础。【方法】2007年早季以泉5B/天丰B的F4代为父本,与不育系泉5A测交,经过多代回交和多年观察筛选,选育早熟优质三系不育系新品种。【结果】选育出的早熟优质不育系伍天A,于2019年通过福建省农作物品种审定委员会审定(闽审稻20190047),表现育性稳定,不育株率100%,不育度99.99%;异交率高,柱头总外露率64.77%;米质优,稻米的主要品质指标:整精米率66.0%、粒长6.7 mm、长宽比3.4、垩白粒率4%、垩白度0.6%、透明度1级、碱消值7.0级、胶稠度50 mm、直链淀粉含量23.8%,其中整精米率、垩白度、透明度、碱消值均达到NY/T593-2013《食用稻品种品质》一等食用籼稻品种品质标准,但胶稠度、直链淀粉含量等指标还不够理想,需在保持其优质早熟等优良特性的基础上,对品质性状进行改造提升;早熟,播始历期均在66 d左右,与天丰A相同;配合力强,伍天A与R713配组育成的三系稻新组合——伍天A/R713于2019年通过福建省农作物品种审定委员会审定(闽审稻20190035)。【结论】伍天A是一个育性稳定、异交率高、米质优、早熟、配合力强的三系不育系,可以配制出优质、多种熟期的三系杂交水稻新组合

4H-Cyclo­penta­[def]phenanthren-4-one

In the title compound, C15H8O, the asymmetric unit contains four independent mol­ecules and crystallizes with aromatic π–π stacking inter­actions[centroid–centroid distances = 3.5326 (18) Å]

1,2,3,4,4b,4c,6,7,8,9,9b,9c-Dodecachloro-4b,4c,9b,9c-tetrahydrocyclobuta[1,2-a;3,4-a']diindene-5,10-dione

The title compound, C18Cl12O2, was synthesized by a solvothermal reaction between sodium and carbon tetrachloride; the oxygen may come from air. The mol­ecule has crystallographic C2 symmetry and contains a four-membered ring, two five-membered rings and two six-membered rings. The five-membered rings are attached to opposite sides of the cyclo­butane group and the six-membered rings are fused to the five-membered rings. In the solid state, the mol­ecule adopts a boat form