Protective Antigens from Virulent Isolates of Fusobacterium necrophorum FN(A)

通过胰蛋白酶裂解坏死梭杆菌FN(A)型毒力菌株菌体,分别以菌体裂解物上清和沉淀作为抗原免疫家兔制备血清。利用SDS-PAGE/Western-blot技术在菌体中筛选出4种具有免疫原性的组分,通过免疫后的攻毒试验,筛选出1种具有免疫保护性的抗原。抗原分离纯化后,进行N端氨基酸序列测定、免疫试验及生物学特性研究,据试验结果可初步判定该抗原为溶血素类似物或一种新发现的抗原物质。该抗原不仅能使机体产生保护性免疫反应,而且不同菌株中此种抗原间可产生明显的交叉免疫。A virulent isolate of the bacterium FN(A) was lysed with trypsin.Supernatants and precipitates of the bacterial lysates were used to prepare anti-FN serum by immunizing rabbits.Four immunogenic components were isolated using SDS-PAGE/Western-blot.Immunized rabbits were challenged,and one protective antigen was screened.After antigen isolation and purification,the N-terminal amino acid sequence was determined and an immunological test and hemolysis test were performed.Results suggested that this antigen is either a hemolysin analogue or a new antigenic substance.The antigen was able to induce a protective immune response as well as generate a marked cross-immune reaction among different bacterial strains.国家科技部奶牛专项(2002BA518A04);; 中国农业科学院特产研究所科研基金项目(tcs-20041

A comparison of the color change of dark muscle in cultured Seriola Cuvier (yellowtail, greater amberjack and goldstriped amberjack) during storage

ブリ属 3 種の保存中における血合筋の肉色変化を比較検討した。各魚種を即殺後，23℃ と 4℃ で保存したところ，カンパチ，ヒラマサよりブリ血合筋の a*値は大きく減少し，肉眼的変化も早かった。各魚種の L*値と b*値には明瞭な変化の違いを認めなかった。ブリ血合筋ミオグロビンのメト化の進行と過酸化脂質の上昇は他 2 種より顕著であった。ブリのミオグロビン含量は他 2 種と比較して低く，ビタミン C は中位に，ビタミン E は少ない傾向にあった。ブリ血合筋の褐変進行が速いのは，ビタミン E 含量の多寡が影響する可能性が考えられた。The dark muscle of cultured Seriola Cuvier (yellowtail, greater amberjack, goldstriped amberjack) was studied for the purpose of comparing the color change of dark muscle during storage at 23℃ and 4℃. The color value (L*, a* and b*), formation of metmyoglobin (MetMb) and formation of thiobarbituric acid reactive substances (TBARS) were measured during storage. Furthermore, the contents of myoglobin, vitamin C and vitamin E of dark muscle in three species were also measured just after killing. The decrease of a* value and the high relative absorbance ratio by MetMb formation, and the increase of TBARS during both storage conditions were observed more prominently in yellowtail than in the other species. The smallest contents of myoglobin and vitamin E and medium contents of vitamin C were found in yellowtail. These results suggest that low vitamin E content might influence faster color deterioration of the dark muscle in yellowtail than other Seriola

マイノリティと社会運動の現在(いま)連続公開研究会講演録

主催:マイノリティの社会運動と政策イシュー形成過程の領域横断比較研究 開催日:2020年8月6日-2021年2月27日 デジタル性暴力とn番部屋 / Post＃米兎(MeToo)のフェミニズム運動 / 香港における社会的葛藤と性暴力 / 周辺から問う-障害女性の運動が重視するもの / 若者支援・ひきこもり支援における「支援者」と「当事者」①-「支援」で感じる不足と過剰 / 若者支援・ひきこもり支援における「支援者」と「当事者」②-自立死援 / 「よき市民」に抗する、逃げる、かわす-学校解放運動とフェミニズム / 威力による性暴力に対抗する韓国の女性運動-ソウル、釜山市長の事例を中心に / 障害者権利条約と障害者運動の戦略-パラレルレポート作成を手がかりとし

JUNO Sensitivity on Proton Decay p→νˉK+p\to \bar\nu K^+ Searches

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in $p\to \bar\nu K^+$ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar\nu K^+$ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is $9.6 \times 10^{33}$ years, competitive with the current best limits on the proton lifetime in this channel

JUNO sensitivity on proton decay p → ν K + searches*

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this study, the potential of searching for proton decay in the $p\to \bar{\nu} K^+$ mode with JUNO is investigated. The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar{\nu} K^+$ is 36.9% ± 4.9% with a background level of $0.2\pm 0.05({\rm syst})\pm$$0.2({\rm stat})$ events after 10 years of data collection. The estimated sensitivity based on 200 kton-years of exposure is $9.6 \times 10^{33}$ years, which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies