可充电锂电池剩余电量预测方法

为了对锂离子电池剩余电量(SOC)进行准确测量,以2 200 mA?h的聚合物锂电池为研究对象,利用Hyperion平衡充放电设备采集6个不同放电电流下(0.7,1.1,1.7,2.2,2.7和3.3A)的放电电压和放电倍率;采取误差反向传播(BP)和径向基函数(RBF) 2个原理不同的神经网络算法进行SOC预测;把采集的样本数据分为训练组和测试组,采用不同的神经网络算法对训练组进行训练后,选择合适的参数构建神经网络,并用测试组数据进行测试;最终比较2种算法的预测效果和误差。研究结果表明:RBF预测结果的相对误差比BP的低,且预测速度更快,RBF较BP更适合于锂离子电池剩余电量的预测。国家自然科学基金资助项目(61571381)~

α-羟基膦酸酯芳甲酸酯的合成、晶体结构和质谱裂解规律研究

α-羟基膦酸酯与各种取代苯甲酸或吡啶甲酸,通过酰氯或缩合剂的作用,合成了一系列的O,O-二烷基-α-苯基-α-(取代芳基甲酸酯基)-甲基膦酸酯的衍生物.它们的合成收率为61%～84%,这些化合物的结构经过核磁(1HNMR,13CNMR和31PNMR)、红外、质谱、元素分析或高分辨质谱确证,同时化合物C1的结构在晶体结构解析上进一步得到证实.利用多级质谱分析了化合物C2,C5和C8的质谱裂解规律,解释了重排离子的形成机制

铜锌原子比对CuO-ZnO/Al_2O_3催化剂合成甲醇性能的影响

以铝乳液的形式引入Al,采用反加共沉淀法制备了一系列Cu与Zn的原子比(简称Cu/Zn原子比)不同的CuO-ZnO/Al2O3催化剂;以合成气为原料,在固定床微型连续流动反应器中评价了CuO-ZnO/Al2O3催化剂合成甲醇的性能;采用XRD、H2-TPR和BET等方法对催化剂进行了表征,考察了Cu/Zn原子比对CuO-ZnO/Al2O3催化剂合成甲醇性能的影响。实验结果表明,Cu/Zn原子比的变化对催化剂前体的物相组成和催化剂的活性有明显影响;当Cu/Zn原子比为3时,催化剂的初活性和耐热后活性最高,其前体中含有较多的锌-孔雀石相((Cu,Zn)2CO3(OH)2),该物相分解时生成还原温度较低的CuO-ZnO固溶体,使Cu与Zn的相互作用增强,提高了催化剂的活性

Yield and Value of Fishery Products of Zhangjiangkou Mangrove Forestry National Nature Reserve

2006年全年对福建漳江口红树林国家级自然保护区红树林主要分布地竹塔村辖区内的海产品类型、产量和价格进行了逐日统计。结果表明:2006年竹塔村滩涂海产品总产量为529956kg(1589.9kg/HM2),远高于一般的红树林。其中缢蛏苗和缢蛏成品的产量最高,分别为312468kg(937.4kg/HM2)和123376kg(370.1kg/HM2),占总产量的59.0%和23.3%。泥蚶、锯缘青蟹成品和泥螺分别占总产量的12.2%、2.3%和2.0%。缢蛏苗以冬季(1月和12月)的产量最高;锯缘青蟹苗年产量为2.59尾/M2,高峰期出现在6月至11月。2006年竹塔村红树林滩涂海产品总产值为1388.0万元(4.17万元/HM2)。研究结果可为红树林生态系统服务功能的评价和红树林的科学管理提供基础数据。Daily investigation of the yield and value of the main fishery products within a mangrove area of Zhuta village in Zhangjiangkou Mangrove National Nature Reserve were surveyed throughout the year of 2006.Results showed that the total yield of fishery products in this area was 529 956 Kg(1589.9kg/hm2) in 2006,much higher than that of the normal mangrove areas.The yields of young and adultSinonovacula constricta were the highest among the fishery products,respectively 312 468 kg(937.4kg/hm2) and 123 376 kg(370.1kg/hm2) ,accounting for 59.0% and 23.3% respectively of the total fishery yields.Tegillarca granosa,adult Scylla serrata and Bullacta exarata were the second important fishery products,accounting for 12.2%,2.3% and 2.0% of the total fishery products respectively.The yield of youngSinonovacula constricta peaked in winter(January and December) and the peak season of young Scylla serrata appeared between June and November.The annual fishery products value was 13.88 million Yuan(41 700 Yuan per hm2) .The results provide a basis for the evaluation of ecological services of mangroves and for its sound management.国家自然科学基金项目(40876046)资

Transition Metal Promoted ZSM-5 Catalysts for the Conversion of Dimethyl Sulfide into Methanethiol

负载过渡金属的zSM-5催化剂用于催化甲硫醚(dMS)转化成甲硫醇(MT)的反应.实验结果表明,催化剂的甲硫醚转化率提高和甲硫醇选择性降低的趋势一样,都是以下顺序:CO/zSM-5>MO/zSM-5>nI/zSM-5>W/zSM-5.表征结果表明,由于过渡金属阳离子(W6+、nI2+、CO3+、MO6+)比Al3+活泼,而改性过程中W6+、nI2+、CO3+、MO6+分别代替了部分Al3+,使得改性催化剂对dMS和MT的化学吸附作用更强.过渡金属的引入使得zSM-5总酸度增强,提高了C―S键的裂解能力,从而改进了催化转化dMS的能力.研究结果发现,在转化dMS的过程中,金属活性位和酸性位之间通过强的协同效应起作用.ZSM-5-supported transition metal catalysts were prepared and used to catalyze the conversion of dimethyl sulfide(DMS) into methanethiol(MT).Test results indicated that the activities of the catalysts for the conversion of DMS increased as follows: Co/ZSM-5>Mo/ZSM-5>Ni/ZSM-5>W/ZSM-5.The decrease in MT selectivity followed the same trend.The characterization results showed that transition metal cations(W6 +, Ni2 +, Co3 +, Mo6 +) replaced some Al3 +sites leading to more active in chemiadsorption of DMS and MT since transition metal cations are more active than Al3 +.The incorporation of transition metals into ZSM-5enhances the total acidity of ZSM-5 and increases its capacity to rupture C―S bonds.This subsequently improves its catalytic behavior in the conversion of DMS.We found that the metal active sites and closely situated acidic sites have a strong synergistic effect when converting DMS

采用原研制剂制备米诺膦酸片及体外溶出度的一致性考察

制备米诺膦酸片,并以原研制剂为参比制剂,采用f2相似因子法对两者体外溶出度的一致性进行考察.建立合适的体外溶出度测定方法,研究参比制剂的溶出情况,通过单因素试验对辅料的用量进行筛选,制备出米诺磷酸片.比较自制品与原研制剂在不同溶出介质中的溶出行为,评价两者体外溶出行为的相似性.结果表明:制备的米诺膦酸片剂与原研制剂在4种不同pH值溶出介质中的溶出相似因子f2均大于50;制备的米诺膦酸片剂与原研制剂体外溶出行为相似.国家自然科学基金资助项目(81302652);;福建省自然科学基金资助项目(2015J01342

三维CT影像资料测量国人心尖区心肌变薄的解剖学验证

背景:在常规心脏三维CT成像检查中可见国人心脏心尖部心肌存在变薄的影像改变,但未见文献报道。认识该影像征象的相关解剖及影像特征,可为临床相关学科的应用及研究提供客观基础。目的:确定国人心尖区心肌最薄点的存在,测量其厚度及位置关系。方法:解剖学观察12个体外心脏标本并利用游标卡尺测量心尖部最薄点厚度及左室心肌最厚处的厚度。选取2009-01/12在厦门大学附属中山医院CT室进行检查的69例无明确心脏疾患患者的三维CT资料,利用三维成像技术显示心尖部结构。测量心尖最薄点、左室心肌最厚处的厚度及心尖最薄点至冠状动脉前降支的距离。结果与结论:解剖学观察显示体外心脏标本心尖部存在心肌变薄区,厚度为(1.74±0.32)mm,左室心肌最厚处为(13.07±1.48)mm;三维CT可清楚显示心尖部心肌最薄区,厚度为(1.27±0.31)mm,左室心肌最厚处为(12.02±1.66)mm;心尖部最薄点到左冠状动脉前降支的距离为(13.70±3.78)mm。统计结果显示解剖学心尖部最薄点厚度与三维CT测量值差异有显著性意义(P<0.05)。结果证实国人心尖区心肌变薄是一种正常解剖结构,标本解剖学及活体三维CT影像学均可清楚显示

Analysis of pre-S/S gene in occult hepatitis B virus infection from blood donors in Dalian,China

目的了解大连地区无偿献血者隐匿性肝炎乙型病毒感染(ObI)的情况和PrE-S/S区基因的变异情况。方法对大连市血液中心2010年12月2日-2013年5月31日的无偿献血者血液标本进行常规ElISA(HbS Ag、抗-HCV、抗-HIV和抗-TP)和HIV/HbV/HCV联合nAT筛查,对于单独核酸检测反应性的献血者加以跟踪或回溯,结合乙型肝炎血清学标志物的试验、鉴别试验、病毒定量试验和半巢式PCr来确定ObI,同时对ObI的PrE-S/S区基因序列与对照组(HbS Ag+序列,gEnbAnk)做比对分析。结果共筛查158 232份血液标本,确定了其中的69份ObI,流行率为1∶2 293(69/158 232)。41例ObI获得PrE-S/S区基因序列:b型6例、C型34例、d型1例;与对照组相比,ObI在S区的氨基酸序列的变异明显(Pb=0.013;PC=0.003),主要变异位点为b型的V14g/A、y161f/S、V168A、P217l和C型的E2g/A/V、T118r/k/A/M、P127T/l/H/S、E164d/g、l175S、S174n。结论大连地区献血者ObI在HbV基因组S区的氨基酸序列存在多个位点的变异,这些变异与ObI的产生存在某种关系,且这种关系受基因型的影响。Objective To understand the prevalence of occult infection of hepatitis B virus(OBI) and the mutations of pre-S / S gene from blood donors in Dalian.Methods From December 2nd,2010 to May 31 st,2013,samples from blood donors in Dalian Blood Center were screened with enzyme-linked immunosorbent assay(ELISA) for HBs Ag,anti-HCV,antiHIV and anti-TP and triplex nucleic acid detection(NAT) for HIV RNA,HBV DNA and HCV RNA.A follow-up was conducted on donors who were tested negative by ELISA but reactive by NAT.OBI was determined by testing the specimens from the follow-up or archive with serological markers of hepatitis B virus,identification examinations,quantitative and semi-nested PCR.The sequences of pre-S / S gene of OBIs and the control group were analyzed(HBs Ag +,Genbank).Results158 232 blood samples were screened,69 of which were OBIs.The prevalence rate of OBIs was 1 ∶ 2 293(69 /158 232).The pre-S / S gene sequences were analyzed in forty-one cases of OBI:6 were type B,34 were type C,and 1 was type D.Comparing the amino acid sequences between the experimental and control groups,there were statistical significance in the S region of OBI(PB= 0.013;PC= 0.003).The main mutation sites of amino acids for type B were V14 G / A,Y161 F / S,V168 A and P217 L while for type C were E2 G / A / V,T118 R / K / A / M,P127 T / L / H / S,E164 D / G,L175 S and S174 N.Conclusion There were multiple mutation loci on the amino acid sequence of OBI from blood donors in Dalian.A particular relationship existed between these mutations in S region from HBV genome and the mechanism of OBI,which was influenced by genotypes.大连市科技计划指导性项目(大卫科发[2013]50号); 大连市医学重点学科优秀卫生专业技术人才培养资助项目(大卫科发[2013]383号

Thermodynamic modeling of the Mg-Pu and Cu-Pu systems

通讯作者地址: Liu, XJ (通讯作者), Xiamen Univ, Dept Mat Sci & Engn, Coll Mat, Xiamen 361005, Peoples R China 地址: 1. Xiamen Univ, Dept Mat Sci & Engn, Coll Mat, Xiamen 361005, Peoples R China 2. Xiamen Univ, Res Ctr Mat Design & Applicat, Xiamen 361005, Peoples R China 电子邮件地址: [email protected] thermodynamic assessment of the Mg-Pu and Cu-Pu systems was carried out by using the calculation of phase diagrams (CALPHAD) method on the basis of experimental data including thermodynamic properties and phase equilibria. The Gibbs free energies of the liquid, fcc, hcp, alpha Pu, beta Pu, gamma Pu, delta Pu, delta'Pu, and epsilon Pu phases were described by the subregular solution model with a Redlich-Kister equation, and those of the intermetallic compounds in the Mg-Pu and Cu-Pu binary systems were described by the sublattice model. A consistent set of thermodynamic parameters were derived for describing the Gibbs free energies of solution phases and intermetallic compounds in the Mg-Pu and Cu-Pu binary systems. An agreement between the calculated results and experimental data is obtained. (C) 2009 Elsevier B.V. All rights reserved.National Natural Science Foundation of China 50425101 5077108

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目的 研究高危型人乳头瘤病毒（HR-HPV）感染相关的宫颈病变程度与抗人乳头瘤状病毒（HPV）抗体水平的相关性,探讨HPV致病的免疫学问题。方法 选取2012年1月-2013年6月在该院妇产科门诊就诊的女性中选取60例病理确诊为女性宫颈病变（CINⅠ及以上）,且宫颈脱落细胞的DNA检测为HR-HPV阳性者为研究组,根据组织学检测结果将研究组进一步分为低度病变组30例（CINⅠ）和高度病变组30例（CINⅡ或Ⅲ）。对照组为经核酸检测无HPV感染且病理诊断未见癌前病变的门诊患者60例,按年龄进一步分为低年龄组和高年龄组。低年龄组和高年龄组与低度病变组和高度病变组的年龄差异无统计学意义（P〉0.05）。分别抽取研究组及对照组外周血,检测其抗HR-HPV L1 Ig G抗体及中和抗体滴度,比较研究组与对照组抗体阳性率及抗体滴度水平的差别。结果 研究组血清中的抗HR-HPV L1 Ig G抗体阳性率及抗体滴度均高于对照组（P〈0.05）;低度病变组患者血清中的抗HR-HPV的中和抗体滴度高于相应对照组（P〈0.05）,而高度病变组的抗HR-HPV的中和抗体阳性率及抗体水平与相应对照组比较差异无统计学意义（P〉0.05）。结论 宫颈病变患者血清中抗HR-HPV L1 Ig G抗体升高,说明HPV感染可引起机体的体液免疫反应。低度病变组的中和抗体水平相对较高,可能是机体产生的中和抗体阻止了病毒的进一步感染。高度病变组的Ig G抗体和中和抗体均低下,说明进入CINⅡ/Ⅲ后HPV已经逃避了免疫系统的监视。基金项目：厦门市科技局项目（3502220124050）;2011年福建省科技计划项目资助计划,青年创新项目（20111）00310517