基于AHP解决客户订单分离点的定位问题

首先介绍了延迟化策略的基本内容,并对客户订单分离点的内涵及影响其定位的因素进行了比较详细地阐述,接着又介绍如何运用层次分析法解决客户订单分离点的定位问题

自愿性内控报告信号价值的投资者认同及甄别

文章首次基于自愿性内控信息披露主体及载体的不同,从投资者市场反应的角度实证检验了披露行为信号价值的差异。基于投资者市场反应(CAr值)的结论表明,非国有企业的内控自评行为不能彰显自身价值,而鉴证报告则可以弥补这一缺陷;国有企业的自评报告可以彰显公司质量,而鉴证报告进一步强化了这一效果

长喙毛茛泽泻的花器官发生

用扫描电镜对长喙毛茛泽泻（ＲａｎａｌｉｓｍａｒｏｓｔｒａｔｕｍＳｔａｐｆ．）的花器官发生进行了观察。该种的花器官发生在泽泻科中既典型又比较特殊。其特殊之处在于从花原基的发生直至最外轮６枚雄蕊原基的发生过程都存在单向发育：３个萼片原基和３个花瓣原基的发生存在次序性，萼片原基和花瓣原基均为顺时针发生，邻近花序侧生分支复合芽的萼片原基和花瓣原基倾向于优先发生；最外轮６枚雄蕊的发生是成对的按对萼的形式发生。这是以往对该属花器官发生研究没有注意到的。由雄蕊原基向心皮原基的转变发生在与最外轮６枚雄蕊相交替的６个位点

Strain Response of FBG at Liquid Nitrogen Temperature

对光纤Bragg光栅（FBG）液氮（77 K）下的应变传感技术及应变特性进行了研究.实验和分析表明：常温下FBG反射谱中的单个中心峰在低温下会劈裂为多峰,它产生于光纤、粘贴胶和金属基底热膨胀系数间的差异引起的强烈非均匀热弹性应变,使常温下均匀的光栅变啁啾化.建立了多种技术手段,成功消除了低温多峰现象,并测得了FBG低温和常温下的应变传感特性.实验结果表明：FBG的应变灵敏系数与温度无关

新城疫病毒株F48E9对CT26小鼠结肠癌的溶瘤治疗作用

目的 分析新城疫病毒株F48E9对CT26小鼠结肠癌的体内外肿瘤杀伤作用和F48E9静脉注射BLAB/c小鼠的安全性数据,评估新城疫强毒株F48E9用于溶瘤治疗的潜力,为后续基于强毒株F48E9进行基因组改造提供科学依据。方法 利用CCK-8试剂盒分析F48E9对CT26肿瘤细胞的体外杀伤效果,通过瘤内注射病毒评价F48E9对CT26荷瘤小鼠的溶瘤治疗效果,以及通过尾静脉注射病毒评估F48E9对健康BALB/c小鼠的潜在毒副作用。结果 MOI为0.1的F48E9对CT26细胞生长可表现出明显的抑制作用,随着MOI的升高,F48E9对细胞生长的抑制作用明显增强;0.1 m L浓度为2×10~7 pfu/mL的F48E9对BALB/c小鼠CT26皮下移植瘤的生长有显著抑制作用,治疗组的平均生存期为38.4 d,未治疗组的平均生存期为15.2 d;免疫组化分析显示F48E9对CT26小鼠移植瘤细胞的增殖有明显抑制作用;F48E9尾静脉注射正常BALB/c小鼠的安全性评估实验显示,该毒株对小鼠无明显副作用。结论 新城疫强毒株F48E9对CT26小鼠结直肠癌有较好的溶瘤治疗潜力,可作为候选病毒株通过后续的反向遗传学改造建立更安全有效的溶瘤病毒株,为肿瘤研究与治疗提供新手段。厦门市重大科技创新平台项目(No.3502Z20131001)资

Study on Tobacco- Leaf Inventory Management Strategy Based on Revenues Sharing Mechanism

文中以福建省两烟物流一体化为背景,建立了基于收益共享机制的烟叶代管策略模型,然后采用SHAPlEy值法来确定收益共享比例,并引入了风险修正因子,修正了物流公司与复烤厂之间的收益分配,探讨了物流公司的整合能力、所承担的风险大小、复烤厂烟叶库存成本占总成本之比对收益共享比例的影响。在此基础上,通过数值分析论证了该方法的可行性。分析结果表明,收益共享比例与物流公司库存整合能力系数、承担风险大小、复烤厂烟叶库存成本占总成本之比成正比,采用带修正因子的SHAPlEy值法对于物流公司与复烤厂之间的收益分配更加合理。Based on the background of integrated- logistics of cigarette and tobacco leaf in Fujian province,this paper builds a model revealing revenue sharing mechanism on tobacco- leaf inventory management strategy.Then Shapley value method is adopted to determine the revenue sharing proportion,risk factor is introduced to fix distribution of profit between Tobacco Logistics Company and redrying factory,and this paper's discussion will show revenue sharing ratio is influenced by the coefficient of inventory integration ability,the risk of Logistics Company and inventory cost of tobacco leaf accounts for the ratio of the total cost of redrying factory.On this basis,using the numerical analysis demonstrates the feasibility of this method.The analysis results show that the coefficient,the risk and the ratio is proportional to the revenue- sharing ratio,Shapley value method with risk factors is more reasonable for distribution of profit between tobacco logistics company and redrying factory.中国烟草总公司福建省公司“两烟物流一体化运行模式研究与实践”项目; 国家自然科学基金项目(71371159); 浙江省科技厅软科学研究计划(2014C35018

Gene Expression and Activities Analysis of a New Fusion Protein (RGD)3/tTF

为了发展一种新型的融合蛋白(RGD)3/tTF用于肿瘤血管的选择性栓塞治疗,利用PCR技术重组(RGD)3/tTF融合基因,克隆于pET22b(+)载体,表达于E.coliBL21(DE3)。用镍柱纯化融合蛋白。凝血实验与FⅩ活化实验检测融合蛋白tTF组分的活性。间接ELISA分析(RGD)3/tTF与αvβ3的特异结合能力。pET22b(+)/(RGD)3/tTF重组质粒成功获得并表达于E.coliBL21(DE3)。纯化蛋白(RGD)3/tTF能有效诱发血液凝固,活化FⅩ。(RGD)3/tTF与αvβ3的特异结合能力比RGD/tTF提高了32%。新型融合蛋白(RGD)3/tTF已在E.coli系统成功表达,表达蛋白保持tTF的活性并显示比RGD/tTF更高的与αvβ3的结合能力。 【英文摘要】 To develop a new fusion protein (RGD)3/tTF for the therapy of the selective thrombosis of tumor blood vessels. The fused gene (RGD)3/tTF was reconstructed by PCR, was cloned into vector pET22 b(+),and expressed in E.coli BL21(DE_3). The fusion protein was purified through Nickel-affinity chromatography column. The tTF activity of the fusion protein was detected by clotting assay and FⅩ activation assay. The specific binding of (RGD)3/tTF to α_vβ_3 was analyzed by indirect ELISA. The recombinant plasmid pET2...福建省自然科学基金(No.C0410004);; 厦门大学科技创新基金资助(No.XDKJCX20053026)。~

Study on Problems and Strategy of Integrated-logistics of Cigarette and Tobacco Leaf in Fujian Province

两烟物流一体化是烟草行业物流建设的重点和方向,福建省在推进两烟物流一体化建设时面临着县公司仓库烟叶交接模式弊端初显、信息化建设不全面、物流标准化有待改进三个方面的问题。文章在分析这些问题的基础上,结合运筹学模型,得出龙岩烟草物流可采取中心库烟叶交接模式。提出了烟叶分拣看板管理作业标准、烟叶包装材料创新、两烟运输车辆改进以及两烟评价标准体系构建的方案,这对进一步行业两烟物流一体化建设具有一定的借鉴意义。Integrated-logistics of cigarette and tabacco leaf is always the construction emphasis and direction in tobacco industry.During promoting the construction of integrated-logistics of cigarette and tabacco leaf, Fujian province has to face the emerging drawbacks of county-level company warehouse's cigarette-tobacco transfer mode, incomplete informationization construction and logistics standardization need to be improved.According to operations research model, our paper concludes the proposal that it will be benefit for further advancing construction of Fujian province's integrated-logistics of cigarette and tobacco leaf by using transfer mode of centralized inventory, management operation standardization of tobacco leaf separation spectaculars, innovation of tobacco leaf package material, improvement of tobacco transport veicles and system establishment of tobacco's evaluation standard, thereby solving the above problems.中国烟草总公司福建省公司“两烟物流一体化运行模式研究与实践”项目; 国家自然科学基金项目;项目编号:71371159; 浙江省科技厅软科学研究计划项目;项目编号:2014C3501