Discussion about architectural originality

建筑是具有独特表现形式的艺术品,除了要满足实用功能之外,还需要具有一定的审美要求。如何做出让人欣赏的建筑,就需要有自己的再创造,也就是所谓的独创。当今建筑行业的发展快速,建筑的独创性受很多条件的制约,其发展空间有限。何为独创性,如何在有限的空间进行创新,如何解决建筑所谓的创新,建筑设计者如何创新才能做到适量,将是本文论述重点。The architecture is an unique form of expressive art,which not only need to meet practical function,but also need to satisfy some certain aesthetic requirements.The appreciation of the architecture based on its own re-creation,which is the so-called original.In today's rapid development of the construction industry,building of originality subject to many conditions,its development space is limited.What is the original,how to innovate in limited space,how to solve the innovation problem of building,how the building designers to innovate appropriately,will be the focus in this paper

The new architectural expression of Minnan Architechure

地域性理论早已被广大建筑学者和从业者所熟知,但将其理论付诸于建筑设计过程并予以实施一直是值得探讨的课题。本文通过对闽南地域建筑文化的叙述,思索现代建筑如何实现地域性的经典理念,并结合若干新闽南建筑实例的探究,表现笔者对于新闽南建筑风格设计的思索。The regional theory has been widely known by students and architects.It is a subject worth being explored that how to put the theory into practice of architectural design.By discussing the local culture of Minnan region,combined with some examples,the writer is supposed to think about how to implement the regional concept in modern architecture and do a research of the architectural style

Analyse the Creation of Suzhou Garden With Pore Structure

本文通过对孔隙结构概念进行论述,研究其在苏州园林墙缘、合院、庭园空间的不同形式的塑造,并分析孔隙性在空间感知方面的处理手法,探究苏州园林造园的精髓。The paper discusses the concept of pore structure,and also researches the different forms of creations in wall space,yard spce and garden space of Suzhou traditional gardens.It analyses the methods of spatial perceptual,which persuing the quintessence of Landscape Gardening in Suzhou gardens

Development and stability test of compound ketoconazole ointment

目的 制备复方酮康唑软膏并考察其稳定性。方法 以酮康唑、莫匹罗星和糠酸莫米松为主药，以聚乙二醇（PEG）为基质制备软膏；利用影响因素试验考察软膏中药物的稳定性。结果 PEG400和PEG3350的比例为2：1时，软膏的黏度最佳，易于涂展。制成软膏后，高温下糠酸莫米松和莫匹罗星稳定性良好；酮康唑有少许分解，加入0.5%的抗坏血酸棕榈酸酯（L-A）后，酮康唑的含量明显提高。加速试验发现，放置6个月后软膏的颜色无变化，3种药物的含量均在98%以上。结论 本实验成功制备了新型复方酮康唑软膏，药物稳定性良好。Objective To prepare compound ketoconazole ointment and perform the stability study.Methods Ketoconazole, mupirocin and mometasone furoate were used as active pharmaceutical ingredients （API）. PEG mixture was used as matrix to prepare the ointment.Stability of the API in the ointment was evaluated by the stress tests.Results The optimal ratio of PEG400 to PEG3350 for the ointment matrix was 2：1. Mometasone furoate and mupirocin in the ointment were stable to the high temperature（40℃）while ketoconazole had some degradation. The stability of the API was improved by addition of 0.5% of L-A. During the accelerate test, the ointment had no color change and the API percentages were above 98%. Conclusion The novel compound ketoconazole ointment was successfully prepared and the formulation stability was excellent.福建省自然科学基金项目（2010J01218

海域基准价格评估:厦门案例研究

近年来,随着国家资源管理体制改革的加快,海域资源市场化配置程度不断提高,海域招拍挂即将成为海域使用权出让的主要方式。对海域基准价格进行研究,可以科学确定海域使用权的价格,为海域资源市场化配置提供科学支撑。本文建立了海域定级和海域基准价格评估方法,并利用建立的方法评估了厦门市货运港口用海、客运港口用海、游乐场用海和游艇泊位用海的海域基准价格。结果显示,厦门市各级各类海域基准价格差异很大,各地区各类用海的海域基准价格在11.04～89.32万元/公顷之间。从区域看,同一区域不同用海类型的海域基准价格相差很大,厦门岛周边海域基准价格普遍较高,与陆域的经济发展水平相对一致;从用途看,同级别海域游艇泊位用海年均海域基准价格最高,货运港口用海最低

Robust deployment strategy for security data collection agent

With the frequent occurrence of “network black production” incidents,attackers strategically launch target attacks with the idea of “profit-seeking”.Existing network monitoring systems lack accurate and effective monitoring strategies for “strategic attacks”.Therefore,in an adversarial environment,how to optimize the deployment of collection agents for better monitoring results becomes an extremely important issue.Based on this,a robust deployment strategy of collection agents was proposed for the above mentioned problem.Firstly,the idea of attack-defense game was introduced to measure the collection agents,threat events and their relations,then the MADG model was built.Secondly,considering that the traditional accurate solution algorithm cannot solve the problem,the robust acquisition agent deployment algorithm called RCD algorithm was designed to approximate the problem by using the sub-module and non-growths of the objective function.Finally,the RCD algorithm was verified.The experimental results show that the above model and method is feasible,effective and expandable

三重疗法治疗雄激素性脱发疗效分析

目的:通过三重疗法治疗雄激素性脱发,并进行疗效分析。方法:66例雄激素性脱发病人随机分为试验组与针刺组,每组各33例。试验组采取针刺、梅花针联合实按灸疗法,针刺组采取针刺疗法。记录两组患者的疗效及伴随症状评分情况。结果:试验组的总有效率为81. 82%,针刺组的总有效率为57. 58%。两组的疗效比较差异具有统计学意义(P <0. 05)。治疗后,试验组的伴随症状评分均低于针刺组,差异均具有统计学意义(P <0. 05)。结论:电针、梅花针联合实按灸疗法治疗雄激素性脱发疗效显著,临床上具有推广及应用价值。中国中医科学院“十三五”重点领域研究专项第一批(No.ZZ10-011-1-2

人死亡受体5全长基因的构建及转染胶质瘤细胞

目的构建人死亡受体5(death receptor5,DR5)全长基因真核细胞表达载体pcDNA3.1/DR5,pcDNA3.1/GFP/DR5,并观察其转染胶质瘤细胞U138的效果。方法通过重叠PCR获得DR5全长编码序列,构建pcDNA3.1/GFP/DR5,pcDNA3.1/DR5表达载体,利用脂质体转染试剂盒,分别将2种质粒pcDNA3.1/GFP/DR5、pcDNA3.1/GFP共转染胶质瘤细胞U138,转染后72h,半定量逆转录聚合酶链反应(RT-PCR)检测DR5mRNA的表达,流式细胞术检测DR5的表达强度、检测Anti-DR5对胶质瘤细胞U138生长的影响。结果获得了DR5全长编码序列,成功瞬时转染U138,RT-PCR、流式细胞术检测结果表明,转染后U138细胞DR5mRNA、蛋白水平的表达明显增加,Anti-DR5可以明显抑制U138细胞的生长。结论获得了DR5全长编码序列,探索到成功转染DR5的最佳方法,为稳定筛选高表达DR5的U138细胞提供依据

基于内毒素血症探讨皂术茵陈方对非酒精性脂肪性肝炎大鼠的影响

目的 基于内毒素血症探讨皂术茵陈方防治非酒精性脂肪性肝炎(NASH)大鼠的影响及其作用机制。方法 采用随机数字表法将40只大鼠分为5组,即正常组、模型组、皂术茵陈方组、盐酸吡格列酮组及培菲康组,每组8只。除正常组外,其余32只大鼠采用高脂饮食16周建立大鼠NASH模型,在造模第9周开始,皂术茵陈方组给予皂术茵陈方水提液60 mg/(kg·d)灌胃,盐酸吡格列酮组给予盐酸吡格列酮10 mg/(kg·d)灌胃,培菲康组给予培菲康210 mg/(kg·d)灌胃,正常组及模型组均给予双蒸水10 mL/(kg·d)灌胃,共治疗8周。第16周末经腹主动脉取血,生化法检测肝组织甘油三酯(TG)水平,苏木精—伊红(HE)染色观察肝组织病理学变化。终点显色法检测血浆内毒素(LPS)含量。ELISA法检测肝组织肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-1β、IL-6等炎症因子的表达水平。结果 与正常组比较,模型组大鼠肝组织显示出典型的NASH组织学特征,出现重度脂肪变性,不同程度的炎细胞浸润和坏死灶。大鼠肝湿重、肝指数、肝脏TG含量、血浆LPS水平、肝组织TNF-α、IL-1β、IL-6等炎症因..