アレイアンテナを用いた埋没生存者探査レーダに関する研究

電気通信大学200

チュウガクセイ ヲ タイショウ ト シタ コミュニケーション キョウイク プログラム ト ソノ コウカ ノ ケントウ

研究報

In Situ Hybridization法によるヒト子宮頸部異形成ならびに子宮頸癌でのras癌遺伝子mRNA発現に関する研究

A method of DNA-RNA in situ hybridization (ISH) with a nonradioactive photobiotin-labelled DNA probe was established for identification of H-ras mRNAs in fresh frozen tissues of nude mouse tumor and human cervical tumor. In order to elucidate the role of ras onco-gene in the process of carcinogenesis of human uterine cervical cancer, we studied the expression of ras oncogene mRNA in histological specimens of various lesions of human uterine cervix. The fre-quency of enhanced H-ras mRNA expression was increased in accord with the grade of malignancy from 25% in mild dysplasia and 33% in moderate dysplasia to 60% in severe dysplasia and 64% in carcinoma in situ. In invasive squamous cell carcinoma, 53% of the tumors showed an increased H-ras mRNA expression. It was suggested that, in conjunction with our previous immunohistochemical study by anti-p21 monoclonal antibody (Sagae et al. Cancer 66 : 295-301, 1990), the expression of ras oncogene correlates with the early phase of carcinogenesis of squamous cells of the uterine cervix

短期入院ボツリヌス療法を用いた持続可能な多職種チーム医療連携

othe

Statistics on operations at Hara Genitourinary Hospital (1971-1991)

The statistical analysis of the inpatients and operations in our department from April, 1971 to March, 1991 revealed a total of 9, 170 operations. One of the biggest changes in treatment is a marked increase in closed surgery. This includes endourological surgeries; transurethral resections of prostate and bladder tumor (TUR-P, TUR-Bt), percutaneous nephrolithotripsy (PNL), transurethral uretero-lithotripsy (TUL) and extracorporeal shock-wave lithotripsy (ESWL). From 1976 to 1980 there were 721 open surgical procedures (71.0% of cases) and 295 closed procedures (21.0% of cases). This ratio has now been reversed completely. From 1986-1991, there were 342 open procedures (8.2% of cases) and 3808 closed procedures (91.8% of cases). The main reason for this change was the introduction of the new techniques PNL, TUL and ESWL. Other important observations include: The incidence of emergency operations was higher in this private institution than that seen in non-private hospitals. From 1986, there was an increase in the use of PNL and TUL for the management of urinary calculi, and from 1988, ESWL has overtaken PNL and TUL in the treatment of this condition. Recently the limitations of ESWL have been appreciated and the value of a combined approach to therapy, for selected cases, is being recognized. A total of 238 ileal or ileocecal conduits were created with good results. A low complication rate has been observed with preservation of renal function