地铁区间矿山法BIM建模标准研究

目前地铁区间针对矿山法的BIM建模标准研究相对较少,也尚未出台相关的国家标准,为BIM技术在地铁施工中全过程全工法的应用,研究和实践矿山法BIM建模标准。在工作分解结构基础上进行矿山法模型构件的拆分,结合实际施工情况得到构件类型表。将拆分的各个构件进行编码,并根据施工阶段构件模型精细度的要求,进行矿山法BIM模型的构建,使模型的信息能更加有效地表达,为地铁区间应用矿山法提供指导

Correlation analysis between bone metabolism and blood stasis in perimenopausal women

目的探讨围绝经期女性骨代谢状况与"血瘀"的关联性。方法 132例符合纳入标准的围绝经期女性按年龄每5岁为一组,分为4组,采用电化学发光法检测不同阶段Ⅰ型胶原氨基端前肽(PINP)、Ⅰ型胶原羧基端肽β特殊序列(β-CTX)、骨钙素N-端中分子片段(N-MID)等骨代谢指标,同时检测血液流变学指标,并对其进行"血瘀"量化评分、甲襞微循环评分,相关数据采用多元回归等统计学进行分析。结果 PINP与全血中切粘度、血瘀量化评分、甲襞微循环评分存在显著的正相关(P<0.01);β-CTX与血瘀量化评分、甲襞微循环评分存在显著的正相关(P<0.01),与红细胞电泳时间存在显著负相关(P<0.01),与全血低切粘度、红细胞刚性指数存在正相关(P<0.05);N-MID与全血中切粘度、血瘀量化评分、甲襞微循环评分存在显著正相关(P<0.01)与全血低切粘度存在正相关(P<0.05)。结论围绝经女性骨代谢状况与"血瘀"关系密切,血瘀是导致围绝经女性骨代谢状况发生变化而发生骨质疏松的重要因素之一。Objective To discuss the correlation between bone metabolism and blood stasis in perimenopausal women. Me thods132 cases of perimenopausal women meeting the inclusion criteria were divided into 4 groups by every 5-year age. Type I collagen amino-terminal propeptide( PINP),carboxy-terminal peptide β special sequence( β-CTX),and molecular osteocalcin N- terminal fragment( N-MID) were detected with electrochemical luminescence at different stages. Blood rheology,blood stasis quantitative score,and microcirculation score were simultaneously detected. Data were analyzed using multiple regression method. Re sults PINP was positively correlated with shear viscosity of whole blood,blood stasis quantitative score,and microcirculation score( P <0. 01). β-CTX was positively correlated with blood stasis quantitative score,microcirculation score,lowshear whole blood viscosity,and erythrocyte rigidity index( P < 0. 01),but was negatively correlated with erythrocyte electrophoresis time( P <0. 01). N-MID was positively correlated with whole blood viscosity,blood stasis quantitative score,microcirculation score( P <0. 01),and lowshear whole blood viscosity( P < 0. 05). Conclusion Bone metabolism and blood stasis are closely related in perimenopausal women. Blood stasis is one of the important factors leading to osteoporosis and change of bone metabolism in perimenopausal women.福建省医学创新课题(2012-CXB-26);; 福建省中医药课题(WST201205

Comparison of uncut Roux-en-Y anastomosis and traditional Roux-en-Y anastomosis in the totally laparoscopic distal gastrectomy for gastric cancer: An analysis of multiple centers' data

目的对比非离断式(Uncut)Roux-en-Y吻合和传统Roux-en-Y吻合应用于全腹腔镜远端胃癌根治术后消化道重建的安全性和短期疗效。方法回顾性分析国内10家单位共60例远端胃癌根治术后全腹腔镜消化道重建的胃癌病人临床资料,根据消化道重建方式不同分为Uncut Roux-en-Y组(Uncut组)34例,传统Roux-enY组(传统组)26例。结果 Uncut Roux-en-Y吻合在消化道重建时间方面用时更短[(51.5±13.3)min vs.(80.4±16.2)min,P=0.000],出血量更少[(60.0±35.6)m L vs.(132.9±65.1)m L,P=0.000],且在进食半流饮食时间方面具有优势[(4.6±1.5)d vs.(7.2±2.3)d,P=0.000]。两组病人在留置胃管时间、术后排气时间、进食流质时间和术后住院时间方面差异无统计学意义。两组病人均无围手术期死亡病例,并发症发生率差异无统计学意义(8.8%vs.7.7%,P=0.875)结论 Uncut Roux-en-Y吻合和传统Roux-en-Y吻合应用于全腹腔镜下消化道重建安全可行,Uncut Roux-en-Y吻合在重建时间和控制出血量方面具有优势。Objective To compare the security and short-term effect of the digestive tract reconstruction during the totally laparoscopic distal gastrectomy for gastric cancer between the Uncut Roux-en-Y anastomosis and the traditional Roux- en- Y anastomosis. Methods The clinical data of 60 gastric cancer patients with digestive reconstruction underwent totally laparoscopic distal gastrectomy between December 2012 and June 2015 in 10 domestic hospital were analyzed retrospectively. According to the difference of digestive reconstruction,it can be divided into the Uncut Rouxen-Y anastomosis group with 34 patients and the traditional Roux-en-Y anastomosis group with 26 patients. Results In uncut Roux-en-Y anastomosis group,the operative time in digestive reconstruction was shorter[(51.5±13.3)min vs.(80.4±16.2)min,P=0.000]; the intraoperative blood loss was less[(60.0±35.6)m L vs.(132.9±65.1)m L,P=0.000];semi-liquid diet time was earlier[(4.6±1.5)d vs.(7.2±2.3)d,P=0.000]. However,there was no difference between the two groups on nasogastric tubegastrointestinaltwo groups on nasogastric tube,gastrointestinal transit,fluid diet and the duration of postoperative hospital stay. Both groups had no death case during the perioperative period and there was no significant statistical difference in the postoperative complication rates(8.8% vs. 7.7%,P=0.875).Conclusion The Uncut Roux- en- Y anastomosis and the traditional Roux-en-Y anastomosis are both safe and feasible for the digestive reconstruction under the totally laparoscopic distal gastrectomy for gastric cancer. Besides,the Uncut Roux- en- Yanastomosis has other advantages such as less reconstruction time and less bleeding.广东省科技计划项目(No.2014A020212591

Comparison of the simulated and LIDAR measured atmospheric density and temperature in transitional flow regime

The understanding of the atmosphere in the transitional flow regime is quite limited,due to the limited accuracy of measurement data.In the proposed paper,the atmospheric density and temperature at around 100 km altitude are analyzed,by using numerical simulation,empirical model,satellite data an..

钾促进钴钼耐硫CO变换催化剂的XPS和TPR表征

用 XPS和 TPR谱学表征方法 ,研究钾助剂对负载型 Co-Mo-K-O/γ-Al2 O3水煤气耐硫变换催化剂的作用 .XPS表征显示 ,硫化态催化剂随着钾添加量的增加 ,低价态钼和 S2 - 增加 ,( S-S) 2 - 受抑制 ,( Mo4+ +Mo5 + ) /Mo6 + 质量比为 0 .8～ 1和较多的 S2 - 物种有利于提高催化剂的低温活性 .TPR表征结果示出 ,硫化态及工作态催化剂皆出现α、β 2个吸氢峰 ,可分别归属 Mo6 + → Mo5 + 和 Mo5 + → Mon+ ( n=4 ,3,2 )的还原过程 ;工作态催化剂 α峰峰温较硫化态低 ,β峰为宽峰带低价钼混合峰 ;吸氢峰的大小与催化剂低温活性密切相关

Effects of transfected HSP70 on p38MAPK signal pathway

目的:探讨热休克蛋白 (HSP70 )在人胶质瘤细胞BT 32 5 p38MAPK信号通路中的作用。方法:用脂质体介导法将hsp70基因导入人胶质瘤细胞BT 32 5中 ,倒置显微镜观察转染细胞的形态学及粘附性变化 ,紫外线照射 30min后 ,采用免疫组化和Western blot方法测定转染前后HSP70的表达水平及照射前后 p38MAPK表达情况。结果:免疫组化和Western blot证实hsp70基因成功转染入BT 32 5中 ,转染细胞受到紫外线照射后 p38MAPK表达减弱。结论:体外转染hsp70基因可抑制紫外线照射后BT 32 5细胞 p38MAPK的表达. Objective To study the role of HSP70 in p38MAPK signal transduction of human glioma cells BT 325.Methods pBBS212 hsp70 gene was transfected into BT 325 cells by lipofectin. The morphological and adhesive changes of the cells were observed under an inverted microscope. The level of HSP70 was measured by immunohistochemistry. Then the transfected cells were put into ultraviolet (UV) for 30 minitues, and expression of p38MAPK and HSP70 were examined by immunohistochemistry and Western blot methods bo...国家自然科学基金资助项目 (30 1 0 0 2 1 8);; 高等学校骨干教师资助计划 (2 0 0 0 - 65 - 66);; 留学归国人员科研启动基金资助项目 (1 999- 747

福建石斑鱼产业发展形势分析

石斑鱼是重要的海水养殖鱼类,福建省的石斑鱼全产业链产值超50亿元,2017年养殖产量占全国总产量的22.10%。笔者在石斑鱼产业发展调研过程中发现石斑鱼产业仍面临育苗水平不高,养殖病害较严重的挑战,建议实施种业创新、建设示范基地、拓展精深加工及培育特色品牌,推进产业转型升级

p38MAPK与HSP70关系的初步研究

高等学校骨干教师资助计划 ;; 留学归国人员科研启动基金([1999] 747号

Effects of transfected HSP70 on p38MAPK signal pathway

目的　探讨热休克蛋白 (HSP70 )在人胶质瘤细胞BT 32 5 p38MAPK信号通路中的作用。方法　用脂质体介导法将hsp70基因导入人胶质瘤细胞BT 32 5中 ,倒置显微镜观察转染细胞的形态学及粘附性变化 ,紫外线照射 30min后 ,采用免疫组化和Western blot方法测定转染前后HSP70的表达水平及照射前后 p38MAPK表达情况。结果　免疫组化和Western blot证实hsp70基因成功转染入BT 32 5中 ,转染细胞受到紫外线照射后 p38MAPK表达减弱。结论　体外转染hsp70基因可抑制紫外线照射后BT 32 5细胞 p38MAPK的表达 【英文摘要】 Objective To study the role of HSP70 in p38MAPK signal transduction of human glioma cells BT 325.Methods pBBS212 hsp70 gene was transfected into BT 325 cells by lipofectin. The morphological and adhesive changes of the cells were observed under an inverted microscope. The level of HSP70 was measured by immunohistochemistry. Then the transfected cells were put into ultraviolet (UV) for 30 minitues, and expression of p38MAPK and HSP70 were examined by immunohistochemistry and Western blot methods bo...国家自然科学基金资助项目 (30 1 0 0 2 1 8);; 高等学校骨干教师资助计划 (2 0 0 0 - 65 - 66);; 留学归国人员科研启动基金资助项目 (1 999- 747

生命意义的探寻——对话埃克哈特，一行禅师与周昌乐

厦门大学图书馆“人文社科实验室” “学会活动”（183） 标题：生命意义的探寻——对话埃克哈特，一行禅师与周昌乐 主讲人：樊林君 厦门大学人文学院2019级博士班国学专业 内容： 生命的意义何在？这一亘古常新的话题，三位当代哲人在各自的著作中给出了颇有意味的答案。著有《当下的力量》的德国学者埃克哈特，《你可以不怕死》的越南籍一行禅师，以及著有《明道显性：沟通文理札记》、从科学跨界到人文的厦大教授周昌乐。他们成长于迥然不同的文化背景，彼此对生命意义的探寻与讲述，有何异同？他们的思想是否殊途同归？这在学理上与为人上给我们何种启发？ 讲座系列： 哲学系硕博学术沙龙 第 100 场 时间：2019年10月27日（星期日），晚上19：00点 地点：厦门大学图书馆三楼 321讲