Effects of Psychological Intervention on Immunological Function in Cancer Patients

目的:通过心理干预前后免疫参数的变化,了解心理干预能否提高癌症患者的免疫功能。方法:运用病例对照实验设计,采用多因素综合分析统计方法,对120例(采集到血样者81例)患者进行比较研究。结果:化疗期间经心理干预后,患者的各项免疫参数均有不同程度的提高; NK细胞活性对心理行为的变化比较敏感,干预后明显提高; 实验组免疫球蛋白三项指标化疗前后比较稳定,但对照组化疗后明显下降。癌症患者的愤怒表达和掩饰性性格特点与NK细胞活性显著相关; 影响免疫功能的因素随免疫参数的不同而异; 各种影响因素以综合作用为主,部分因素间交互作用明显。结论:心理干预对提高癌症患者的免疫功能起到一定作用,但其机制和稳定性有待进一步研究

心理干预对癌症患者免疫功能的影响

目的：通过心理干预前后免疫参数的变化，了解心理干预能否提高癌症患者的免疫功能。方法：运用病例对照实验设计，采用多因素综合分析统计方法，对120例（采集到血样者81例）患者进行比较研究。结果：化疗期间经心理干预后，患者的各项免疫参数均有不同程度的提高；NK细胞活性对心理行为的变化比较敏感，干预后明显提高；实验组免疫球蛋白三项指标化疗前后比较稳定，但对照组化疗后明显下降。癌症患者的愤怒表达和掩饰性性格特点与NK细胞活性显著相关；影响免疫功能的因素随免疫参数的不同而异；各种影响因素以综合作用为主，部分因素间交互作用明显。结论：心理干预对提高癌症患者的免疫功能起到一定作用，但其机制和稳定性有待进一步研究

应对策略在癌症患者心理干预中的中介作用

目的：探讨在对癌症患者实施心理干预过程中应对策略及其相关因素的中介作用。方法：运用病例对照实验设计，对实验组病人进行了为期3个月的心理干预，选用疾病应对问卷作为主要测查工具，采用多因素综合分析统计方法，对120名住院化疗病人进行了比较分析。结果：干预组病人在干预后较多运用主动认知和主动行为策略，较少运用回避方法，对照组则变化不大；干预后病人情绪状态、功能状况以及生活质量的改善与所采用的应对方法有一定关系：与主动认知应对方法呈正相关，与回避性应对方法呈负相关，与主动行为应对方法则关系不明显。结论：应对策略及其相关因素在癌症患者心理干预中起一定的中介作用

The Mediating Effects of the Coping Styles and Related Factors on Psychological Intervention in Cancer Patients

目的:探讨在对癌症患者实施心理干预过程中应对策略及其相关因素的中介作用.方法:运用病例对照实验设计,对实验组病人进行了为期3个月的心理干预,选用疾病应对问卷作为主要测查工具,采用多因素综合分析统计方法,对120名住院化疗病人进行了比较分析.结果:干预组病人在干预后较多运用主动认知和主动行为策略,较少运用回避方法,对照组则变化不大;干预后病人情绪状态、功能状况以及生活质量的改善与所采用的应对方法有一定关系: 与主动认知应对方法呈正相关,与回避性应对方法呈负相关,与主动行为应对方法则关系不明显.结论:应对策略及其相关因素在癌症患者心理干预中起一定的中介作用

JUNO Sensitivity on Proton Decay p→νˉK+p\to \bar\nu K^+ Searches

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this paper, the potential on searching for proton decay in $p\to \bar\nu K^+$ mode with JUNO is investigated.The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits to suppress the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar\nu K^+$ is 36.9% with a background level of 0.2 events after 10 years of data taking. The estimated sensitivity based on 200 kton-years exposure is $9.6 \times 10^{33}$ years, competitive with the current best limits on the proton lifetime in this channel

JUNO sensitivity on proton decay p → ν K + searches*

The Jiangmen Underground Neutrino Observatory (JUNO) is a large liquid scintillator detector designed to explore many topics in fundamental physics. In this study, the potential of searching for proton decay in the $p\to \bar{\nu} K^+$ mode with JUNO is investigated. The kaon and its decay particles feature a clear three-fold coincidence signature that results in a high efficiency for identification. Moreover, the excellent energy resolution of JUNO permits suppression of the sizable background caused by other delayed signals. Based on these advantages, the detection efficiency for the proton decay via $p\to \bar{\nu} K^+$ is 36.9% ± 4.9% with a background level of $0.2\pm 0.05({\rm syst})\pm$$0.2({\rm stat})$ events after 10 years of data collection. The estimated sensitivity based on 200 kton-years of exposure is $9.6 \times 10^{33}$ years, which is competitive with the current best limits on the proton lifetime in this channel and complements the use of different detection technologies