Study on diatom in ballast water of pelagic vessels

应用新型压舱水采样器采集了5艘进入厦门港的国际远洋船舶14个压舱水水样,通过对样品中硅藻的分析、鉴定,共发现硅藻37属111种(包括变种和休止孢子),其中赤潮种28种,潜在有毒种1种,非本海域种6种:STEPHArOPyXIS TurrIS;CHAETOCErOS COnVOluTS;C.CrInITuS;C.AurIVIllIIS;C.nEOCOMPACTuM;C.SubSAlSuM。各样品中硅藻丰度值在0.08x103/l~5.96x103/l之间,种类数(已定种)在6~36之间。结合硅藻组成和丰度可以推断压舱水的可能交换地。与前人的研究结果对比反映出压舱水可能导致新的外来有害生物入侵的潜在危害性,相关职能部门应加强压舱水的监管工作。14 ballast water samples were collected by a new sampling instrument from five pelagic vessels which have been and clean frequently in Xiamen Harbor.According to analyzing and identifying the species and the abundances of diatom in the samples,37 genus 111 species diatoms(containing varieties and hypnospore) were discovered,which included 28 kinds of red tidal species,one kind of latent toxic species,and 6 kinds of non-native species,such as Stepharopyxis turris;Chaetoceros convoluts;C.crinitus;C.aurivilliis;C.neocompactum;C.subsalsum.The abundances of diatom in each sample ranged from 0.08×103/L to 5.96×103/L,and specie's numbers(identified species)of them were amongst 6 to 36.Based on the diatoms assemble with abundance,the possible position of ballast water's change can be deduced.The discharge of ballast water may cause the potential hazards of new exotic harmful organism's invasion.The results of comparisons between this investigation and previous studies on ballast water can provide scientific base for the related government departments,so that it should strengthen the management on the ballast water.国家自然科学基金资助项目(40306018);国家科技支撑项目(2006BAC11B04

Room-temperature quantum interference in single perovskite quantum dot junctions

钙钛矿材料由于其高量子产率、载流子迁移率和独特的光致发光特性而在光电材料领域存在诸多潜在的重要应用。研究钙钛矿材料在纳米尺度下电荷输运的独特尺寸效应对钙钛矿光电器件的设计和开发具有重要的指导意义。洪文晶教授课题组基于机械可控裂结技术自主研发了具有皮米级位移调控灵敏度和飞安级电学测量精度的精密科学仪器，对南开大学李跃龙副教授团队合成的钙钛矿量子点进行了深入表征，研究工作成功将量子干涉的研究体系拓展至在光电领域具有重要应用的钙钛矿材料领域，为未来制备基于量子干涉效应的新型钙钛矿器件提供了一种全新的思路。 这一跨学科国际合作研究工作是在化学化工学院洪文晶教授、英国Lancaster 大学物理系Colin J. Lambert教授以及南开大学电子信息与光电工程学院李跃龙副教授的共同指导下完成的。化工系硕士研究生郑海宁、Lancaster University大学Songjun Hou博士、南开大学硕士研究生辛晨光为论文第一作者。博士后林禄春，博士研究生谭志冰、郑珏婷，硕士研究生蒋枫、张珑漪，本科生何文翔、李庆民等参与了论文的研究工作。刘俊扬特任副研究员、师佳副教授和萨本栋微纳米研究院杨扬副教授也参与了部分指导工作。The studies of quantum interference effects through bulk perovskite materials at the Ångstrom scale still remain as a major challenge. Herein, we provide the observation of roomtemperature quantum interference effects in metal halide perovskite quantum dots (QDs) using the mechanically controllable break junction technique. Single-QD conductance measurements reveal that there are multiple conductance peaks for the CH3NH3PbBr3 and CH3NH3PbBr2.15Cl0.85 QDs, whose displacement distributions match the lattice constant of QDs, suggesting that the gold electrodes slide through different lattice sites of the QD via Auhalogen coupling. We also observe a distinct conductance ‘jump’ at the end of the sliding process, which is further evidence that quantum interference effects dominate charge transport in these single-QD junctions. This conductance ‘jump’ is also confirmed by our theoretical calculations utilizing density functional theory combined with quantum transport theory. Our measurements and theory create a pathway to exploit quantum interference effects in quantum-controlled perovskite materials.This work was supported by the National Key R&D Program of China (2017YFA0204902, 2014DFE60170, 2018YFB1500105), the National Natural Science Foundation of China (Nos. 21673195, 21503179, 21490573, 61674084, 61874167), the Open Fund of the Key Laboratory of Optical Information Science & Technology (Nankai University) of China, the Fundamental Research Funds for the Central Universities of China (63181321, 63191414, 96173224), and the 111 Project (B16027), the Tianjin Natural Science Foundation (17JCYBJC41400), FET Open project 767187—QuIET, the EU project BAC-TO-FUEL and the UK EPSRC projects EP/N017188/1, EP/M014452/1. 该工作得到国家重点研发计划课题（2017YFA0204902）、国家自然科学基金（21673195、21503179、21490573）、厦门大学“人工智能分析引擎”双一流重大专项等项目的资助，也得到了固体表面物理化学国家重点实验室、能源材料化学协同创新中心的支持

Y型聚乙二醇干扰素琢-2b注射液治疗HCV基因2/3型慢性丙型肝炎患者疗效和安全性的多中心随机对照试验研究

目的以标准剂量的聚乙二醇干扰素(Peg IFN)α-2a联合利巴韦林作为阳性对照,评价新型试验药物Y型Peg IFNα-2b注射液联合利巴韦林治疗2型/3型慢性丙型肝炎(CHC)患者的疗效和安全性。方法采用多中心、随机开放、阳性药对照的Ⅲ期临床试验,筛选符合要求的2型/3型CHC患者,按照2:1的比例随机分配到Y型Peg IFNα-2b组和Peg IFNα-2a组,同时口服利巴韦林,疗程24 w,停药随访24 w。采用Abbott Real Time HCV Genotype II检测HCV基因型,采用Cobas Taq Man实时定量PCR法检测血清HCV RNA水平。详细记录不良事件。主要疗效指标为持续病毒学应答(SVR),并进行非劣效检验。结果本试验实际入组2型/3型CHC患者255例,实际治疗241例。全分析集(FAS)数据显示,158例试验组和83例对照组患者SVR分别为85.4%(95%CI 79.94%~90.94%)和79.5%(95%CI 70.84%~88.20%,P=0.2402);对符合方案分析集(PPS)人群分析显示,试验组和对照组患者SVR分别为87.9%(95%CI 82.45%~93.27%)和85.9%(95%CI 77.82%~94.01%,P=0.7060),率差的95%可置信区间均符合非劣效标准;对PPS人群分析显示,85.8%受试者获得了早期病毒学应答(RVR),RVR的阳性预测值为90.1%;试验组和对照组不良事件发生率相似,分别为95.6%和95.2%,严重不良事件发生率分别为3.8%和3.6%。结论应用Peg IFNα联合利巴韦林治疗2型/3型CHC患者,新型试验药物Y型Peg IFNα-2b具有与对照药物Peg IFNα-2a相似的疗效和安全性。国家科技部“十二五”重大专项(编号:2012ZX10002-003)；“重大新药创制”十二五科技重大专项(编号:2012ZX09303019)

对不同工人群体SCL-90的元分析

目的：比较分析不同工人群体SCL-90九因子与全国常模的差异。方法：收集筛选出近10年关于不同工人群体的SCL-90研究成果30项，将其九个因子得分与常模进行效应量值计算，并对30项研究的各因子分进行聚类分析。结果：不同工人群体SCL-90的30项研究与全国常模比较的平均效应量值d为0、36；九个因子的d值，只有躯体化为0.82，处在高水平，其他八个因子均在0.50以下，处在低水平；聚类分析的结果与其一致。结论：除个别特殊物理环境下的工人外，不同工人群体的心理健康基本正常。1986年全国常模的躯体化分量表有进一步研究的需要；工人群体身心健康研究有待继续深化

A Meta-analysis on SCL-90 of Different Worker Groups

目的 :比较分析不同工人群体SCL - 90九因子与全国常模的差异。方法 :收集筛选出近 10年关于不同工人群体的SCL - 90研究成果 30项 ,将其九个因子得分与常模进行效应量值计算 ,并对 30项研究的各因子分进行聚类分析。结果 :不同工人群体SCL - 90的 30项研究与全国常模比较的平均效应量值d为 0 .36 ; 九个因子的d值 ,只有躯体化为 0 .82 ,处在高水平 ,其他八个因子均在 0 .5 0以下 ,处在低水平 ; 聚类分析的结果与其一致。结论 :除个别特殊物理环境下的工人外 ,不同工人群体的心理健康基本正常。 1986年全国常模的躯体化分量表有进一步研究的需要 ; 工人群体身心健康研究有待继续深

Development and Application of Quantitative Structure-activity Relationship (QSAR) Model for Acute Toxicity of Selenastrum capricornutum Based on Extreme Gradient Boosting Algorithm and Feature Selection Method

Algae as the main primary producers in aquatic food webs play an important role in ensuring the sustainability of aquatic ecosystems.However,a large number of chemicals have been released into the aquatic environment with the development of industrial production and countless other human activities,posing a great threat to algae.If algae are endangered,they will inevitably affect other aquatic organisms.Therefore,it is imperative to assess environmental toxicity on algae.The assessment requires a large amount of toxicity data through experimental measurements,which is costly and time consuming.Quantitative structure activity relationships (QSAR) is a good alternative method to solve these problems.In this study,QSAR models for the acute toxicity of Selenastrum capricornutum were constructed by using the extreme gradient boosting (XGB) algorithm and feature selection method.53 acute toxicity data were gathered from Web of Science and China National Knowledge Infrastructure.The optimal model achieved a coefficient of determination (R_(TR)~2) of 0.97 for training set,a coefficient of determination(Q_(EXT)~2) of 0.78 for validation set,and a leave-one-out cross-validation coefficient (Q_(LOO)~2) of 0.51,respectively.In addition,the results showed that the topological charge number,total atomic number and electronegativity of the compounds were the key factors affecting the acute toxicity of Selenastrum capricornutum.On this basis,the established QSAR model and EPI Suite were used to predict the acute toxicity of 16 typical polycyclic aromatic hydrocarbons(PAHs) to algae,respectively.This study provides an efficient predictive tool for obtaining acute toxicity data of algae and helps to accelerate environmental risk assessment of algae

不同土壤水分下限对大棚滴灌甜瓜产量和品质的影响

以厚皮甜瓜品种伊莉莎白为材料,研究大棚滴灌条件下营养生长期不同土壤水分下限(75%田间持水量,I75;65%田间持水量,I65;55%田间持水量,I55;45%田间持水量,I45)对甜瓜生长、产量、品质以及灌溉水分利用效率的影响,并以沟灌(G75)作为对照。结果表明,株高、茎粗、叶面积和地上部干重均随着营养生长期土壤水分下限的降低而减小。I75果实横径、皮厚和肉厚均最大,果形指数最小;I65果实纵径最大。果实品质方面,总可溶性固形物(TSS)含量为:I65>I55>I75>I45;可溶性糖含量为:I55>I65>I45>I75;维生素C(Vc)含量为:I55>I65>I75>I45;可溶性蛋白质含量为:I55>I65>I45>I75;游离氨基酸总量为:I45>I65>I55>I75。I75的产量和平均单果重最高;I65的灌溉水分利用效率最高,达到29.16kg/m3,相比沟灌对照提高76.4%,可节水58.1%,而平均单果重仅比对照下降3.2%。综合考虑产量和品质,可以选择65%田间持水量作为武汉地区厚皮甜瓜营养生长期适宜的土壤水分下限指标

Investigation of Droplet Dynamics Under Shear Flow

Abstract The dynamics of droplet under shear flow was investigated in normal gravity and microgravity. Drop under shear flow has many applications in aerospace such as aircraft de-icing and environmental control and life support system in space station. Shape analysis of the droplet showed that drop in microgravity have a greater contact angle and height, but a smaller contact radius, than that in normal gravity. The difference between advancing and receding contact angle &theta;a-&theta;r is greater in microgravity than that in normal gravity under the same wind speed. The effect of airflow on the droplet is mainly dependent on the We number and the dimensionless number k&prime;, which characterizes the ratio of wind force and adhesion force. the k&rsquo; in microgravity is larger than that in normal gravity. The droplet exposed to airflow from static to motion state can be divided into three regimes.</p