Application of 5S management method on the materials science & engineering experimental teaching and personnel training

将5S管理方法引入材料科学与工程实验室建设与实验教学管理中。通过建立5S推行组织、确定试运行实验室的方法学习5S管理模式,以点带面,建立逐步在整个实验教学中心、在学生培养中推行5S管理的方法。The 5S management method is introduced into material science and engineering laboratory construction and experimental teaching management.By establishing an implementation organization, determining the test run laboratory, the 5S management mode is studied.And then fan out from point to area, it's gradually set up in the whole experiment center.It's also implemented during the personal training of the students in the university.教育部“十二五”国家级实验教学示范中心:厦门大学材料科学与工程专业实验教学示范中心(教高厅函[2012]13号); 教育部卓越工程师教育培养计划:厦门大学材料科学工程(教高厅函[2013]38号); 教育部第二批高等学校特色专业建设点:材料科学与工程(教高函[2007]31号); 福建省本科高校专业综合改革试点:材料科学与工程专业(闽教高[2012]41号

Construction an Opening Materials Science and Engineering Experimental Platform for all Students in the University

厦门大学材料科学与工程实验教学中心是2012年教育部批准建设的国家级专业实验教学示范中心。该实验教学中心针对不同学科、不同层面的学生,开设面向本专业的A类专业实验课程、面向校内相关理工科专业的B类材料基础实验课程以及面向全校各专业的C类材料通识实验课程。通过分层次、分体系的实验课程设置,教学科研协同发展和校企联合培养的实验教学模式,以及智能化管理系统的建设,实现实验室对全校师生的开放,全面提高实验中心的辐射示范作用。Materials science and engineering experimental teaching center of Xiamen University is an national professional teaching demonstration center, which was approved to construct by the education Ministry in 2012. According to the knowledge background and different requirement of the students in the university the experimental teaching center offers three level experimental courses： Course A is for the students in material college, which contains many specialized materials experiments; Course B is for the students major in science and engineering in the university, which contains basic materials experimental courses; Course C is for all students in the university, which contains general study materials experimental courses. Through the three level course settings and relevant teaching methods, as well as a controlled, visualized and intelligent management system, the center orderly opening to the students comes true. It is benefit to improve the role of radiation and demonstration of the center

Preparation of potassium diformate by methyl formate and potassium hydroxide

联系人：李清彪. 第一作者：詹国武（1986—），男，学士.[中文文摘]本研究采用甲酸甲酯、氢氧化钾、甲酸为原料，一步反应制备二甲酸钾。系统地考察了影响产品收率的主要因素，优化了工艺条件，结果表明，当n(MF)/n(KOH)=1.20，n(HCOOH)/n(KOH)=1.44，反应时间为30min，反应温度为55℃时，二甲酸钾产品收率可达 98.8%。产品经红外光谱分析及成分测定，符合质量标准。[英文文摘]In this study, methyl formate, potassium hydroxide and formic acid were used as raw materials for one-step synthesis of potassium diformate. The main factors affecting the quality and yield of product were investigated. The optimal conditions for reaction were: molar ratio of MF to KOH 1.20:1, molar ratio of HCOOH to KOH 1.44:1, reaction time 30 min and reaction temperature 55℃. The product met the quality standard of potassium diformate after infrared spectrum analysis and composition determination.厦门大学创新性实验计划资助项

Clinical analysis of perimenopausal women presenting initially with dry eye symptom

目的探讨围绝经期妇女的干眼症状与干眼病诊断的相关性。方法分析56例具有干眼症状的围绝经期妇女眼部检查的临床资料,观察主诉为干眼症状患者的干眼病确诊率及其关系。结果56例以干眼症状为主要表现的围绝经期妇女,确诊水液缺乏型干眼17例(30.4%),蒸发过强型干眼12例(21.4%),混合型干眼8例(14.3%);不能诊断干眼病的19例(33.9%),最终诊断为围绝经期综合征。结论围绝经期妇女干眼病确诊率较高(66.1%),但部分干眼症状可以只是围绝经期综合征的精神神经症状的一种表现,临床诊断干眼应慎重。 【英文摘要】 Objective Diagnosis and treatment of dry eye are important for improving living quality.Present paper was to investigate the correlation between dry eye manifestations and diagnosis of dry eye disease in perimenopausal women.MethodsThe clinical data of 56 perimenopausal women presenting initially with dry eye symptoms including ocular symptoms,slit-lamp examination,tear film break-up time,basal and reflex Schirmer test,vital staining(fluorescence and rose bangle),and meibomian gland dysfunction examination ..

Advanced preparation technologies and strategies for molecularly imprinted materials

Molecularly imprinted polymers (MIPs) prepared by molecular imprinting technology (MIT) are polymers with specific recognition sites matching the shape,size and functional groups of template molecules,which can selectively identify and enrich target analytes (template molecules),and have been widely used in sample pretreatment,chemical/biological sensing and other fields.However,in the processes of preparation and applications of MIPs,there are still some problems,such as difficult elution of template molecules,fewer effective recognition sites,low binding capacity,low mass transfer rate and poor recognition in aqueous media.As a multidisciplinary technology,MIT has developed rapidly by borrowing and integrating related advanced technologies/strategies of other fields.Consequently,a variety of new imprinting technologies and strategies have continuously emerged,which not only effectively solve the abovementioned problems but also push forwards the development of novel MIPs and widen their applications.In this paper,orienting the applications of MIPs in sample pretreatment,sensors and stimuli responses,some advanced preparation technologies and strategies for MIPs materials are highlighted,including ingenious imprinting technologies (surface imprinting,nanoimprinting;controlled/living polymerization,solid-phase synthesis,etc.),special imprinting strategies(multi-template/monomer imprinting,dummy imprinting,boronate affinity imprinting,etc.),and stimuli-responsive imprinting (magnetic,temperature,pH responsive,etc.).Fundamental features of the advanced imprinting technologies/strategies and their utilizations for MIPs preparations along with representative applications are described in details,involving important issues and research challenges.Firstly,a comprehensive overview of main imprinting technologies and strategies for MIPs preparation in sample pretreatment application is provided.In this regard,MIPs are used as selective adsorbents of various extraction technologies such as solid-phase extraction (SPE),dispersive SPE and magnetic SPE.Aiming at high selectivity and high adsorption capacity,the MIPs should have ideal morphology,uniform size and excellent surface properties.Besides conventional preparative methods,it is required to introduce new imprinting technologies and strategies,mainly including the ingenious imprinting technologies of surface imprinting,nanoimprinting,controlled/living free radical polymerization(CLRP),click chemistry,hollow porous polymer synthesis technology and solid-phase synthesis,and the special imprinting strategies of multitemplate/monomer imprinting,dummy/segment imprinting,magnetic material and boronate affinity imprinting.Surface imprinting and nanoimprinting technologies are usually adopted by coupling with the abovementioned imprinting technologies and strategies.Secondly,advanced imprinting technologies and strategies for the construction of MIPs-based sensors are summarized.For the sensors,the MIPs as recognition elements can specifically bind target analytes and as transduction elements can generate output signals for detection.</p

Carbon-gold nanocluster ratio fluorescence sensor microsphere as well as construction and application thereof

本发明属于材料科学与工程和环境分析化学领域，具体来说是一种二硫苏糖醇修饰的碳‑金纳米团簇比率荧光传感微球及其构建和对汞离子的高选择、高灵敏检测的应用。传感器利用新型荧光纳米材料碳‑金纳米团簇为荧光源，然后通过DTT在金纳米团簇表面上修饰巯基(‑SH), 用巯基将汞离子吸引到团簇表面, 由于汞离子(5d10)与金离子(5d10)之间存在作用力, 可实现对汞离子的高选择性、高灵敏检测。本发明通过微波葡萄糖和金种子的混合溶液来制备具有双发射波长的碳‑金纳米团簇，简化了比率荧光传感器的构建过程，有效地避免了繁琐的荧光复合材料的制备过程。用于实际水样中汞离子的分析检测，加标回收率在90％以上

一种利用双功能单体协同作用制备铅离子印迹聚合物微球的方法

本发明属于材料科学与工程和环境科学领域，具体的说是一种利用双功能单体协同作用制备铅离子印迹聚合物微球的方法。聚合物为以铅离子作为印迹离子(模板离子)，采用甲基丙烯酸和四乙烯基吡啶作为功能单体，利用悬浮聚合制得的粒径均一的印迹微球。本发明所得微球对铅离子具有高的吸附容量、良好的动态特性、优异的识别选择性和高的重复利用性。该微球结合固相萃取技术实现了对自然水样中的铅离子进行高选择性富集。本发明突破传统使用单一功能单体，提供了使用双或多功能单体进行印迹聚合物制备的新思路。本发明操作简便快捷、成本低、重现性好，具有广泛的应用前景

分子印迹聚合物在磺胺类抗生素残留检测中的 样品前处理应用研究进展

The residues of sulfonamides (SAs) antibiotics cause great harm to organisms and environments. Appropriate sample pretreatment is usually imperative to couple with chromatography / mass spectrometry analysis for the sensitive determination of SAs, ow ing to their low level residues and multiple categories presence in complicated matrices. Molecularly imprinted polymers (MIPs) have the binding sites complementary to the template molecules in shape, size and functional groups. So, MIPs can selectively recognize and effectively enrich target analytes (template) as well as eliminate matrices interferences. Thereby they have been widely applied in the sample pretreatment of SAs antibiotics. In this review, recent advances in sample pretreatment applications of MIPs for determination of SAs residues are summarized, mainly including conventional packed solid-phase extraction (PSPE), dispersive solid-phase extraction (DSPE), magnetic solid-phase extraction (MSPE) and temperature sensitive solid-phase extraction (TSPE). Several challenge is sues of MIPs are given, and some new imprinting technologies and strategies for preparation of MIPs towards SAs are highlighted, such as surface imprinting technology, nanoimprinting technology and molecularly imprinted membrane technology, as well as multi-template imprinting strategy and dummy imprinting strategy. Finally, an outlook on the preparation and pretreatment application of SAs-MIPs is proposed.</p

Ion Imprinting Technology for Heavy Metal Ions

分子印迹技术(molecular imprinting technology,MIT)是指制备对特定目标分子具有专一识别性能的聚合物技术。离子印迹技术(ion imprinting technology,IIT)以离子为模板,通过静电作用、配位作用等与单体结合形成螯合物,聚合后用酸性试剂等将模板离子洗脱,最终制得具有与目标金属离子相对应的三维孔穴结构的印迹材料。作为分子印迹技术的重要分支,离子印迹技术因存在配位作用而具有很多优势,近年来得到了快速的发展。重金属离子是离子印迹领域最典型且最受关注的目标物。本文介绍了离子印迹技术原理、制备及其在金属的痕量和超痕量分析中的优势,针对环境监测中典型重金..

Quantum dot-based protein imprinted polymer microsphere as well as preparation method and application thereof

本发明属于材料科学与工程和生物分离工程领域，具体来说是一种基于荧光量子点的蛋白质印迹聚合物微球及其制备和应用。该微球以巯基乙酸(TGA)和谷胱甘肽(GSH)共同作为稳定剂的CdTe量子点直接作为功能单体，蛋白质为模板分子，多巴胺为交联剂，通过多巴胺的自聚合得印迹聚合物微球。本发明利用量子点的荧光信号进行检测，以功能化的量子点直接作为功能单体，保证了印迹空穴中都含有量子点，能够提高检测的灵敏度。同时，通过多巴胺的自聚合得到印迹聚层，也进一步简化了印迹过程。用于海水和湖水样品中藻蓝蛋白、牛尿样本中牛血红蛋白的分析检测，加标回收率均可达到90％以上，且重复使用性能良好