Study of Financial Regulatory Reform in the Post-Crisis Era

1980年代，美欧发达经济体鼓吹新自由主义，带动经济全球一体化及金融自由化与国际化之潮流。伴随着金融自由化与国际化，美欧金融创新蓬勃发展，金融业欣欣向荣。然而，就在全球经济日趋一体化及金融国际化发展下，美国2007年下半年爆发的次级房贷风暴快速传递蔓延至全球金融市场，相互传染扩大成为自1930年代以来最严重的金融危机，重创美欧发达国家的金融体系，导致全球经济面临自大萧条以来最严重的衰退，迄今已达五年仍未见明显复苏。 金融危机反映金融不稳定的本质，彰显出一向被视为全球金融监管先进标竿的美欧发达国家的金融监管制度是存在有严重的内在缺陷。影子银行规模快速扩展但却未受到适当监管，形成监管套利与监管漏...In the 1980's, the developed countries of America and Europe advocated neoliberalism actively, which facilitated globalization of economy, liberalization and internationalization of finance. Along with financial liberalization and internationalization, financial innovation boom fostered prosperity of the financial sector. While in the context of growing economic globalization and financial interna...学位：经济学博士院系专业：经济学院_金融学(含保险学)学号：1562010015453

消费者价格指数理论与实践问题研究

文章较为详细地考察了消费者价格指数的历史源头——康努斯生活成本指数;在此基础上,引出了消费者价格指数在实践当中的估算形式——拉氏价格指数。文末以案例的形式矫正了人们对编制价格指数的错误认识,并阐释了统计领域现行的编制方法

Effects of the Xitongxiao prescription on apoptosis and proliferation of chondrocytes in knee

目的：探讨膝痛消方对促进软骨细胞增殖和抑制IL-1β诱导的软骨细胞凋亡的作用。方法：体外培养膝关节软骨细胞，用阿利新蓝染色方法检测软骨细胞蛋白多糖，用Ⅱ型胶原免疫荧光染色检测软骨细胞Ⅱ型胶原的表达，以鉴定软骨细胞；用MTS检测软骨细胞的增殖；用IL-1β诱导软骨细胞凋亡，AnnexinV/PI双染检测细胞凋亡。结果：膝关节剥离得到的细胞形态为多角形或梭形，阿利新蓝与Ⅱ型胶原免疫荧光染色均呈阳性，证明分离培养的细胞为软骨细胞。MTS实验结果发现膝痛消方提取物处理软骨细胞后检测到的OD值随浓度增加而增加且显著高于对照组。此外，IL-1β处理诱导软骨细胞凋亡，而膝痛消方提取物能够有效地抑制IL-1β引起的细胞凋亡。结论：膝痛消方能促进软骨细胞的增殖，抑制IL-1β诱导的软骨细胞的凋亡。以上发现为膝痛消方临床上治疗膝关节骨性关节炎提供药理作用依据。Objective:To investigate the effects of the Xitongxiao prescription on the cell proliferation and the inhibition of IL-1β-induced apoptosis of chondrocytes.Methods:To identify chondrocytes,the articular chondrocytes were cultured in vitro;staining with alcian blue was used to detect the protein polysaccharide,and staining with collagen immunofluorescence was used to examine the expression of type II collagen in chondrocytes.The proliferation of chondrocytes was determined by MTS.Apoptosis of chondrocytes was induced by IL-1β,and the effect of apoptosis was tested by Annexin V/PI double staining.Results:The morphology of the cells obtained from the knee joint was polygonal or fusiform.The tested results of Alcian blue and collagen immunofluorescence staining were positive.These together certified that the isolated cells were knee chondrocytes.MTS assay results showed that the detected OD values were dosedependently increased and they were significantly higher than those of the control group.In addition,the apoptosis of chondrocytes was induced by IL-1βtreatment.While the extract of the Xitongxiao prescription could effectively inhibit the IL-1β-induced apoptosis of chondrocytes.Conclusion:The Xitongxiao prescription could promote the proliferation of chondrocytes and inhibit the apoptosis of chondrocytes induced by IL-1β.The above findings may provide one of pharmacological mechanisms of the Xitongxiao for clinical treatment of knee osteoarthritis.厦门市科技计划项目(3502z20144031);福建省自然科学基金计划资助项目(2015J01065)

Progress in functional separator materials for lithium-ion batteries

隔膜是锂离子电池四大关键材料之一,随着锂离子电池在电动汽车、储能等领域的应用不断延伸,对隔膜的性能要求越来越高.本文从安全和电化学性能等角度论述了近年来无机陶瓷改性功能隔膜、聚合物改性功能隔膜及其他功能性隔膜的相关研究进展,并对功能性隔膜的发展提出展望,为从事相关研发的工作者提供一些借鉴.As the application of Li-ion batteries has been expanding from consumer electronics to industrial usage including electric vehicles and energy storage, the separator, which is a critical component of a Li-ion battery, has gained much more attention to improve its performance.This paper reviews the research progress of ceramic coater separators, polymer modified separators and other functional separators from the viewpoint of the Li-ion battery safety and electrochemical performance.Furthermore, the paper also brings on the future prospect of functional separators which provides some references for the development of this area.国家高技术研究发展计划重大项目(2012AA110404); 中航工业产学研合作创新工程专项研究计划(cxy2011XD27)资

巴茱合剂治疗老年性痴呆肾虚髓减证36例

目的观察巴茱合剂治疗老年性痴呆肾虚髓减证的临床疗效。方法选取老年性痴呆肾虚髓减证患者74例随机分为治疗组36例和对照组38例。治疗组给予巴茱合剂口服,对照组给予金匮肾气丸配合银杏叶提取物片(金纳多)口服,疗程3个月。运用阿尔茨海默病评价量表-认知部分(ADAS-cog)、简易精神状态量表(MMSE)评价患者的智能,日常生活能力量表(ADL)评价患者的日常生活能力,中医证候疗效积分评价疗效。结果治疗组总有效率为88.9%,优于对照组71.1%,2组ADAS-cog评分、MMSE评分、ADL评分、中医证候疗效积分较治疗前均有所改善(P<0.05),且治疗组ADAS-cog评分、MMSE评分、中医证候疗效积分改善优于对照组(P<0.05)。2组治疗过程中未见不良反应发生。结论巴茱合剂能够改善老年性痴呆肾虚髓减证患者中医证候、智能及日常生活能力,未见不良反应发生。福建省科技重点项目(2012D064);; 厦门市中医药科研项目(wst201208);; 福建省中医科研课题(wzln201312

在福建东南沿海局部地域献血员中检出HTLV-I

[目的 ]进一步阐明福建沿海 HTL V小流行区 HTL V- 的地理分布特点及毒株的基因类型。 [方法 ]对福建东南沿海莆田地区献血员以国产双抗原夹心法 EL ISA试剂筛选 ,对 EL ISA阳性血清用 Western blot(WB)进行确证。对抗体确证阳性者 ,采集外周血分离淋巴细胞用巢式 PCR扩增 HTL V- env区 gp46片段进行序列分析鉴定病毒亚型。 [结果 ]从 1998年 10月至 2 0 0 0年 4月止 ,共检测 45 6 4份标本 ,结果确证出 16例 HTL V- 抗体阳性者 ,感染率为 0 .35 %。HTL V- 抗体阳性者主要分布在某村献血人群中 ,并具有区域集中的特点。笏石秀屿一带某村献血员中感染率高达 4.7%。7例代表性毒株经病毒序列分析为 HTL V- C亚型 (COSMOPOL ITAN)。[结论 ]福建东南沿海某村献血员中发现 HTL V- 流行。提出在对某一地区人群进行 HTL V筛选时 ,既要注意整个地区“面”的筛查 ,又要注重某个村镇“点”的调查

Direct secretory expression of active microbial transglutaminase in Pichia pastoris

使用异源表达系统直接分泌表达具有活性的微生物谷氨酰胺转氨酶(MICrObIAl TrAnSgluTAMInASE,MTg)是目前最具前景的MTg生产方法之一,但由于产量较低无法实现工业化生产。毕赤酵母是近年来发展出的高效蛋白表达系统。通过采用PrO序列与成熟MTg基因共表达的策略,成功地实现了用重组毕赤酵母分泌表达具有活性的茂原链霉菌STrEPTOMyCES MObArAEnSE MTg。进一步通过对PrO序列和MTg基因拷贝数以及重组酵母培养条件的优化,最终使得MTg在1 l发酵罐中高密度发酵的酶活达到7.3 u/Ml,为MTg的工业化生产奠定了基础。Direct secretory expression of active microbial transglutaminase(MTG) using heterologous hosts is a promising strategy,although its production level still needs to be improved for industrial production.Pichia pastoris is one of the most efficient expression systems developed in recent years.In this study,secretory expression of active MTG was successfully achieved by co-expressing the pro sequence and mature MTG genes in P.pastoris.Furthermore,we optimized the copy number of pro/MTG expression cassettes and the fermentation conditions.MTG production level reached 7.3 U/mL in 1-liter fermentor through high density fermentation,providing the feasiblity for industrial scale preparation of MTG.国家自然科学基金(No.31000026); 中国科学院“知识创新”工程重要方向项目(No.KSCX2-EW-G-15-03)资助~

黄芪对肺腺癌细胞生长抑制的实验研究

目的:研究分化诱导剂黄芪(Astragalus)在体外对人肺腺癌SPC-A-1细胞生长抑制的影响。方法:用不同浓度的黄芪分别处理肺腺癌SPC-A-1细胞后,镜下观察癌细胞的生长情况;测定软琼脂克隆形成率;MTT(噻唑蓝)法测定生长抑制率。结果:不同浓度黄芪处理后细胞的生长明显受到抑制,细胞生长抑制率随黄芪的浓度增加而增加。结论:黄芪对肺腺癌SPC-A-1细胞的生长有明显的抑制作用

The influence of homosexual internalized homophobia on anxiety: taking rejection sensitivity as the mediating variable

目的 探讨同性恋者内化同性恋嫌恶对焦虑的影响及拒绝敏感性起到的中介作用。方法 通过方便取样，采用同性恋嫌恶量表、拒绝敏感性量表及焦虑量表对275份样本进行有效问卷调查，考察我国同性恋者内化同性恋嫌恶及拒绝敏感性及焦虑的现状情况，并探讨内化同性恋嫌恶对焦虑的影响中拒绝敏感性是否存在中介效应。结果 (1)内化同性恋嫌恶与焦虑呈显著正相关，拒绝敏感性分别与内化同性恋嫌恶和焦虑呈显著正相关；(2)拒绝敏感性在内化同性恋嫌恶对焦虑的影响中起部分中介作用，其中总效应为0.352,中介效应为0.129,中介效应占总效应比36.65%。结论 内化同性恋嫌恶显著正向影响焦虑，同时拒绝敏感性起到部分中介作用。</p