507 research outputs found
The effect of nitric oxide on the basolateral 10 pS chloride channel activity in the TAL of the mouse kidney and its regulating mechanism
背景:小鼠肾脏髓袢升支粗段(TAL)可以通过管腔侧的2型钠钾二氯协同转运体(NKCC2)重吸收20-25%的NaCl,并通过管周膜侧的钠钾泵和Cl-通道排出,在尿浓缩机制中发挥着重要作用。有研究表明一氧化氮(NO)对TAL管腔膜侧NKCC2的活性有着显著的抑制作用,并减少TAL对Cl-的吸收。为了保持细胞的稳态平衡,如果管腔膜侧对Cl-的吸收减少了,那么管周膜侧的排出也应减少。电导为10pS的Cl-通道是管周膜侧TAL排出Cl-最重要的离子通道,因此我们推断其活性将受到NO的调控。 目的:本研究将利用细胞贴附式膜片钳技术和Westernblot技术来研究NO对TAL管周膜侧10pSCl-通道...Backgrounds: The thick ascending limb (TAL) is responsible for the reabsorption of 20-25% of the filtered salt load and plays a key role in the urinary concentrating mechanism. Approximately 20-25% of reabsorbed Na and Cl enter epithelial cells in the TAL through apical type II Na+-K+-2Cl- cotransporter (NKCC2) and leave the cell primarily through basolateral Na+-K+-ATPase and Cl- channels, respec...学位:理学硕士院系专业:医学院_生理学学号:2452013115342
转变公共服务职能 建设公共服务型政府
公共服务是21世纪公共行政和政府职能转变改革的核心理念。中国政府公共服务职能转变的根本目标是建立起公共服务型政府,促进公共服务市场化的改革,实现政府公共服务职能的转变
Study on Dynamic Integrity Testing of Pile Foundation Using Multiple Method When Considering Damping
近年来,随着我国城市化进程的加速,桩基被广泛地应用在高层建筑、重型厂房、桥梁、港口码头、海上采油平台等工程上。桩基础作为一种具有承载力高、沉降量小等特点的基础形式,能够将上部结构的荷载直接传到深层稳定的土层中去,从而大大减少基础的沉降和建筑物的不均匀沉降,因此,桩基础在地震区、软土地区、膨胀土地区及冻土地区等被大量使用。随着桩基被迅速和大量地推广和应用,桩基质量带来的工程问题愈来愈多。由于桩基是地下隐蔽结构物,在施工中易于出现各种缺陷(如缩径、断裂、夹泥和沉渣等质量问题),桩基质量好坏将直接影响到建筑结构的安全。因此,必须对施工质量进行检测,以便及时发现问题并采取相应措施,防止工程事故的发生。...In recent years, with the rapid development of urbanization in China, pile foundation is extensively applied in the construction of tall buildings, heavy-duty factory buildings, bridges, docks, offshore oil production platforms, etc. As a foundation type which has the characters of large bearing capacity and small amount of settlement, pile foundation can directly transfer the load of superstructu...学位:工学硕士院系专业:建筑与土木工程学院土木工程系_结构工程学号:2005130257
Research in the usual performance appraisal of civil servants:Taking Siming District Human Resources and Social Security Bureau as an example
《中华人民共和国公务员法》颁布实施以来,全国各省市在公务员考核方面取得了一定的成绩。但是,重定期考核轻平时考核一直是各级政府公务员考核中普遍存在的问题。思明区人力资源和社会保障局(以下简称“思明区人社局”)充分利用自身在公务员绩效考核工作上的基础和优势,大胆创新尝试,将公务员平时绩效考核工作全面推向实践。本文利用绩效考核理论,结合国家公务员管理相关规定,立足思明区人社局实际情况,对该局公务员平时绩效考核工作进行深入地分析研究,试图对其考核体系进行完善,并为公务员平时绩效考核试点研究提供必要的参考和依据。 本文首先简要回顾了公务员绩效考核研究背景,综合阐述了国内外的研究情况,提出了本文研究的内...Since “The civil servant law of the People's Republic of China " was issued and implemented, all provinces and cities of China has made certain achievements in the civil servant appraisal.But, pay attention to regular appraisal and ignore the usual has been a widespread problem in the appraisal of the government departments at all levels of regional governments.Siming District Human Resources and ...学位:管理学硕士院系专业:公共事务学院_公共管理硕士(MPA)学号:1392011115047
A Study on Market Strategy of Copyright Protection For Software Products with Network Externalities
随着高新技术的发展,与其相关的软件产品和服务在生产和消费领域日益凸显出一种新的特性——网络外部性,它对软件厂商所制定的版权保护策略和市场策略等决策都有重要的影响。本文基于软件产品网络外部性的特点,结合消费者效用函数分析并构建了软件产品系列化博弈模型和软件产品定价模型。在软件产品系列化博弈模型中,分析了软件厂商在不同的市场条件下所得到的均衡价格,均衡需求,均衡利润以及总体社会福利状况,并且通过对Symantec和Autodesk两家著名软件厂商的案例分析,更深入的理解如何运用产品系列化策略来促进正版软件的销售,获得市场成功。在软件产品定价模型中,主要是分析了市场上出现盗版软件挤占正版软件市场空间...With the development of high and new-technology, the software products and services have revealed a new feature——network externalities. It has an important influence on the decision of copyright protection and market strategy for enterprises. Based on the feature of network externalities, this article formes the game model of product lines and product pricing combined with the consumer utilit...学位:管理学硕士院系专业:管理学院管理科学系_技术经济及管理学号:20033700
Etude sur les modalités lexicographiques des définitions et des exemples dans le Petit Robert
词典的释义和例证是构成词典的主体部分,被称作词典的灵魂,也是衡量词典功能和质量的主要标准。法国是词典大国,许多词典是词典学研究成果的典范,其中《小罗贝尔词典》当属语文词典之最。它由法国著名语言学家JosetteREY-DEBOVE和AlainREY主编,自1967年第一版问世至今每年更新,吸收了当代世界语言学理论研究发展的新成果,融合了法国词典编纂的先进理念,从收词、释义到例证的编纂,完整地呈现法语语言及其蕴含的丰富历史文化信息,是法语学习者的经典工具书,长期受到各国法语使用者的喜爱。 本文以认知语言学为理论依据,从微观结构入手,通过考察5个法语经典高频词目的释义和例证的特色,深入探讨以下两...La France est un grand pays où la lexicographie est mondialement reconnue, dont la palme revient au Petit Robert, créé sous la direction de Josette REY-DEBOVE et d’Alain REY, lexicographes et linguistes de grande réputation. Depuis la première édition en 1967, ce dictionnaire, tout en adaptant des fruits de recherche des théories linguistiques contemporaines qui évoluent sans cesse, se renouvelle ...学位:文学硕士院系专业:外文学院_法语语言文学学号:3172012115252
A Theoretical and Practical Research on Construction of Legal System of Lablor Delegation
劳务派遣是我国劳动力市场上近些年出现的一种新现象,发展势头迅猛。但劳务派遣出现至今,理论界一直对劳务派遣是毁誉参半:一方面,它在促进就业方面显示独特魅力;另一方面,由于现行立法的缺失,劳务派遣的主体三方的法律关系混乱不清,被视为派遣员工权益受损的“罪魁祸首”。劳务派遣涉及劳动法、民法、社会保障法、保险法、就业促进法等多个学科领域,目前我国对该领域的理论研究相对薄弱,学界未进行过专门和系统的研究。因此,对劳务派遣涉及的法理问题进行研究,具有理论价值。同时,由于现行法律的缺失,劳务派遣的快速发展也产生了诸多问题和缺陷,如何构建相应法律制度在促进就业与维护派遣员工权益之间寻找均衡,也成为劳务派遣实践...Labor delegation is a new phenomenon, which emerges in our labor market in recent years. It has been developing increasingly with grand momentum. The scholars of labor law, however, haven’t agreed on whether the labor delegation is good. On one hand, it promotes employment. On the other hand, owing to lack of relevant regulations on labor delegation, the legal relation among the three parties is c...学位:法律硕士院系专业:法学院法律系_法律硕士(JM)学号:X20020812
Application of Customer Relation Management in E-Government
客户关系管理起源于盈利组织,但是其以服务为核心的理念同样适用于政府的公共服务。随着中国加入WTO,政府的职能和形象也在逐步改变,电子政务开始引入客户关系管理的新理念。首先介绍了中国电子政务的现状,分析了客户关系管理和电子政务的内在联系,并举例说明了客户关系管理在电子政务中的运用。在此基础上对客户关系管理在电子政务中的应用提出了几点建议。Customer relation management(CRM) is derived form for-profit organizations,but the key point of CRM service is suitable for the public service in government management. With China entering WTO,the functions and images of the governments are changing step by step,and the new views of CRM has brought into e-government. The articles introduced the status of e-government firstly,analyzed the internal relations of CRM and e-government,and gave some examples of the applications of CRM in e-government. Finally the authors put forward some advices for the applications of CRM in e-government
Intelligent Parking Control System Based on Embedded Video Acquisition
中文摘要:针对智能交通系统中非车辆停泊区的监控问题,设计出一套基于嵌入式的图像处理系
统,并运用背景差分法等方法基本上能够对
禁止停车的区域自动监控并能够自动提取有
效信息进行处理。系统采用Intel 公司的嵌入
式XScale 微架构处理器和一些嵌入式的外围
芯片,具有操作简单、价格低廉等特点。英文摘要:In this paper, it is presented a control system based
on embedded video acquisition aimed at non-parking
zonecontrolinITS(IntelligentTransportationSystem).
Itisusedbackgrounddifferencingmethodtocontrol
the non-parking zone and pick up the effective
informationautomatically. Thesystemusesembedded
XScale micro-frame processor of Intel and some
embedded Periphery Chip so that it operates easily
and has a low price
Research on the Clinical Pathway PDCA Continuous Improvement System Based on the Theory of Feedback Closed-loop Control System
运用控制论方法,将控制理论领域反馈的闭环控制法、管理学的PDCA循环等方法运用于信息系统的整合建设,建立电子病历一电子医嘱一临床路径一医院管理信息系统的“全闭环”临床路径执行和反馈体系,建立了疾病诊疗规范制定、临床操作服务、过程质量监管三位一体的医疗服务安全质量监测与持续改进闭环体系,临床路径信息管理平台对加强医疗服务安全动态监管,促进科学化、精细化、专业化管理,改善服务水平,提高效率具有不可或缺的重要作用。With the method of control theory, the feedback closed loop control method in the field of control theory, PDCA circulation of management and other methods are applied to the integrative construction of information system. The "closed loop" clinical pathway implementation and feedback system of electronic medical records-electronic medical advice-clinical pathway- hospital management information system is established. The medical service safety quality monitoring and continuous improvement closed-loop system integrating disease diagnosis and treatment specification formulation, clinical operation service and process quality supervision is set up. The clinical path information management platform has an indispensable important role on strengthening the dynamic supervision of medical service security, promoting scientific, refined and professional management, and improving the service level and eficiency.国家自然科学基金面上项目一大数据驱动的抗菌药物使用与管理决策优化研究(编号:71672160
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