Design and Implementation of Performance Management System in Futures Industry

期货行业在金融行业中是比较稚嫩的亚行业，一般规模比较小，盈利能力较弱，但随着我国经济持续发展和金融服务业的开放，期货行业的也将进一步的发展，同时竞争也越来越激烈。要想在这个竞争日趋激烈的市场上立于不败之地，离不开一个优秀的团队，如何对员工进行全面、科学有效的考核，培养出优秀的员工，充分调动的员工积极性，是一个非常重要的任务。 而目前绩效考核的明显缺点在于：对绩效的判断通常是主观的、凭印象的和武断的；不同管理者的评定不能比较；反馈延迟，使员工因好的绩效没有得到及时的认可而产生挫折感，更为糟糕的是引发劣币驱逐良币现象。实践证明，通过绩效管理，可以帮助企业实现其绩效的持续发展；促进形成一个更加绩效...Futures industry is a relatively young industry in the financial industry, generally the size is small, profit ability is weak. But along with the economy sustainable development and the open of financial services industry, futures industry will further development, but the competition will be more and more fierce. Want an impregnable position in the market in the increasingly fierce competition, ...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201123022

高等教育的多学科研究方法:原理、地位和路线

高等教育学正处在走向成熟学科的阶段,我们要以多学科方法来促进高等教育学学科建设。从高等教育研究的对象、高等教育理论的科学属性和高等教育研究的任务来看,高等教育学必须采用多学科的研究方法。多学科研究方法是高等教育研究的根本方法。高等教育的多学科研究要朝实际问题的解决和理论改造两个方面努力,高等教育研究必须坚持“开放、包容、合作”的学科建设特点,并且要逐渐向跨学科研究范式过渡

基于邻域粗糙集的多标记属性约简算法

在多标记学习中,属性约简是解决多标记数据维数灾难的一个关键技术.针对邻域粗糙集属性约简在计算正域代价较大和多标记数据中标记具有不同的强弱性问题,提出了基于邻域粗糙集的多标记属性约简算法.该算法首先利用样本在整个属性空间下到其异类样本的平均距离与到其同类样本的平均距离的差值对标记进行加权;其次,利用取整函数对样本空间进行划分,提出了一种新的多标记邻域粗糙集快速计算正域的方法;最后,根据前向贪心搜索算法进行属性约简,以获得一组新的属性排序.实验给出了5个多标记数据集在4个评价准则上的对比结果,实验结果分析表明了所提算法的有效性.国家青年科学基金项目(N61603173);;福建省自然科学基金项目(2018J01422);;浙江省海洋大数据挖掘与应用重点实验室开放课题(OBDMA201603

Effect and mechanism of TIPE3 interference plasmid on SW480 colorectal cancer growth

目的:通过TIPE3干扰质粒转染SW480结肠癌细胞,验证干扰TIPE3表达对SW480结肠癌细胞生长的影响并探讨相关机制。方法:构建TIPE3; -shRNA-pSIREN-RetroQ干扰质粒,通过脂质体转染法成功将干扰质粒导入SW480细胞,通过RT-PCR、Western; blot检测重组质粒的干扰效率。应用CCK-8方法检测SW480细胞生存率。AnnexinV-FITC/PI流式细胞法检测细胞凋亡。使用West; ern; blot检测细胞增殖、凋亡相关分子的表达情况。结果:成功设计、构建和筛选具有生物活性且干扰效率最佳的TIPE3-shRNA-pSIREN-Ret; roQ干扰质粒。CCK-8检测证实干扰SW480结肠癌细胞TIPE3表达可以抑制细胞生长。流式结果显示,TIPE3-shRNA3干扰组的凋亡率为; (27. 991. 087) %,显著高于正常细胞组(12. 102. 213) %及转染空载质粒组(11. 440. 277 0); %。证实了降低TIPE3表达可以增加SW480对aDR5ScFv所诱导的细胞凋亡敏感性。Western; blot结果显示干扰TIPE3表达可以活化caspase3蛋白,降低p-AKT、p-PDK1、PCNA等分子的表达。结论:干扰TIPE3的表达对; SW480结肠癌细胞具有促进凋亡,抑制增殖的作用。Objective: To study the effect of interference TIPE3 on the colon cancer; cell growth by transfecting SW480 colon cancer cells with the TIPE3; interference plasmid were detected. Methods: Transfecting the; constructed TIPE3-shRNA-pSIREN-RetroQ plasmid to SW480 cells. To; determine the highest interference efficiency plasmid, the mRNA and; protein levels of recombined plasmid were detected by RT-PCR and Western; blot separately and tested the cell proliferation with CCK8. Meanwhile,; apoptosis rate of SW480 cells was determined by flow cytometry assay; with AnnexinV-FITC/PI. To further determined the effects of recombined; plasmid on cell development, the level of protein involved in; proliferation and apoptosis were detected by Western blot. Results: The; most effecient interference plasmids were successfully constructed. We; found that the cell survival rate decreased when interference TIPE3 gene; expressing in colorectal cancer cells. Flow cytometry indicated that; interefering the expression of TIPE3 would increase the sensitivity of; SW480 cell to apoptosis induced by aDR5ScFv. The results of Western blot; showed that low expression of TIPE3 would activate caspase3 and; downregulate the expression of p-AKT,p-PDK1 and PCNA. Conclusion:; Interference TIPE3 could promote apoptosis and inhibit proliferation in; SW480 colon cancer cells.国家自然科学基金; 福建省属公益类科研院所基本科研专项项

微球喇曼激光器的性能研究

由光学球微腔与光纤耦而构成的喇曼激光器大大降低了阈值泵浦功率,明显提高了总体效率.本文对微球喇曼激光器的性能进行了详细的理论模拟研究,从泵浦信号和喇曼信号的速率方程出发,推导出微球喇曼激光器的阈值公式,讨论和分析了微球喇曼激光器的球微腔与熔锥光纤的耦合特性及耦合对激光器阈值的影响,并提出了提高该激光器耦合效率的有效方案

熔锥光纤与球微腔耦合系统的理论模拟

利用H. J. Shaw提出的单模光纤定向耦合器的分析方法并结合微球腔的特性,对熔锥光纤与球微腔系统的耦合特性进行了理论分析和数值模拟。研究表明,由于原本简并的球腔模式受腔体偏心率的影响而解除,系统吸收峰间距减小,Q值( 106 ~107 )比将腔体视为理想球时提高了三个数量级。这与已报道的实验结果相吻合

ERK干扰质粒的构建及对胃癌细胞株BGC823 DcR3表达的影响

目的探讨胃癌发展的分子机制,通过构建ERK1/2shRNA真核表达载体,体外研究其对人胃癌细胞株BGC823ERK1/2蛋白及DcR3表达水平的影响。方法应用PRNAT-U6.1/Neo载体构建ERK1/2基因shRNA重组质粒,经脂质体法导入BGC823细胞中,分别设置对照组、干扰组和U0126抑制剂组。Westernblot法检测转染后BGC823细胞及抑制剂使用后ERK1/2蛋白的表达变化,荧光显微镜检测质粒自带GFP基因的表达情况确认转染效率,ELISA法检测各组细胞上清中DcR3分泌蛋白的表达特点。结果成功构建ERK1/2基因shRNA重组质粒。证明了ERK1/2蛋白的表达与DcR3的分泌水平在BGC823细胞株中呈正相关。结论 ERK1/2干扰质粒明显降低BGC823细胞的ERK1/2蛋白表达水平,ERK信号通路对DcR3的分泌具有重要调控作用,为其下游调控机制的研究奠定了基础

端面泵浦Nd∶YAG连续输出1052nm波长激光器

设计了一个简单紧凑的1052nm波长激光器。首次利用激光二极管(LD)端面泵浦Nd∶YAG晶体,使用镀有高度选择性介质膜的反射镜产生该波段的激光。激光阈值为0.3W,当808nm波长泵浦光功率达到18W时产生了3.5W的1052nm波长激光输出。光-光转换效率为20%,输出激光功率波动不超过3%

Anti-Angiogenic and Anti-Inflammatory Effects of SERPINA3K on Corneal Injury

SERPINA3K is a member of the serine proteinase inhibitor (SERPIN) family. Here we evaluated the therapeutic effects of SERPINA3K on neovascularization and inflammation in a rat cornea alkali burn model that is commonly employed to study corneal wounding. Topical treatment of the injured rat cornea with SERPINA3K (20 µg/eye/day) for 7 days significantly decreased the neovascular area, compared with the groups treated with BSA or PBS. The SERPINA3K treatment also ameliorated the corneal inflammation as evaluated by the inflammatory index. Furthermore, SERPINA3K enhanced the recovery of corneal epithelium after the alkali injury. Toward the mechanism of action, SERPINA3K down-regulated the expression of the pro-angiogenic and pro-inflammatory factors, vascular endothelial growth factor and tumor necrosis factor-α and up-regulated the expression of the anti-angiogenic factor, pigment epithelium-derived factor. SERPINA3K specifically inhibited growth of vascular endothelial cells. Meanwhile, SERPINA3K significantly up-regulated the expression of EGFR in the corneal epithelium. These findings suggest that SERPINA3K has therapeutic potential for corneal inflammation and NV