Research on the Thermal Conductivity of Lithium Battery Materials: Callaway Model and Artificial Neural Network Model

随着移动式和便携式电子设备的广泛应用，锂离子电池在人类社会中扮演的角色越来越重要。从翱翔太空的航天飞机到潜入深海的潜水艇，锂离子电池的身影随处可见。然而，锂离子电池在给人类带来便利的同时，也具有一定的安全隐患。并且，随着锂离子电池的发展，其安全问题受到越来越多的关注，成为了一个制约锂离子电池发展的重要因素。经过分析，锂离子电池的安全问题主要表现为发热、燃烧、爆炸等现象，这些问题归根结底就是热问题。造成锂离子电池热问题的原因很多，其中一项比较重要的就是电池的电极材料的热学性质。广泛用于锂离子电池正极材料的LiCoO2是一种典型的层状结构物质。因此，研究该种材料的热导率，对于锂离子电池安全性的研究...With the wide application of mobile and portable electronic devices, Li-ion Batteries are playing an increasingly important role in society. From the space shuttle in the outer space to the submarine in the ocean, Li-ion Batteries can be seen everywhere. Lithium ion batteries, however, bring convenience for mankind. At the same time, they also have some potential safety hazard. And with the develo...学位：工学硕士院系专业：物理科学与技术学院_工程硕士(电子与通信工程)学号：1982013115299

Research on the Democratic Progressive Party’s Political Party Culture and its Origin

政党文化作为政党的一个隐性特征，一直以来都被作为政治亚文化或者组织文化进行研究，近年来才作为一个独立的研究对象获得了学界的广泛关注。虽然是一种政党的隐性特征，但是政党文化却处于变化的常态之中，也在经常性地影响政党行为。由于本文研究对象的特殊性，本文认为政党文化是以政党意识形态与价值取向为核心的，以党员对内对外的态度为内在基础，以政党形象和行为模式为外在形式所表现出来的一套隐性价值体系。 民进党的雏形最早可以追溯到上个世纪60、70年代风起云涌的党外运动，以争取民主和参政权利的党外人士在1985年进行了整合，并于翌年成立了民主进步党。民进党在成立之初就显示了其不同于国民党的特质，这种特质的核心...As a recessive character of the political party, political party culture is always studied by the methods of political subculture and organizational culture, and it’s researched as an independent object of study just in these years. Although it’s a recessive character, political party culture always changes and affects political party’s behavior. Because of the particularity of object of study, th...学位：法学硕士院系专业：台湾研究所_中外政治制度学号：2562008115277

锌介导的炔酰胺串联氧化/卤化反应合成α-卤代酰胺

α-卤代酰胺是一类十分重要的羰基化合物,广泛存在于众多天然产物和生物活性分子之中.本工作实现了通过卤化锌同时作为催化剂和卤素源的炔酰胺串联氧化/卤化反应,从而避免使用其他的外加卤化试剂.该反应可以中等到良好的产率得到一系列合成上非常有用的α-卤代酰胺化合物

“秤砣虽小压千斤”——解析金属离子在纳米药物自组装中的功能设计

目前,化疗的最大障碍是化疗药物在杀死癌细胞的同时对人体正常细胞,尤其是免疫细胞造成损伤.将化疗小分子药物特异性地递送到肿瘤部位,从而提高疗效并降低其毒副作用是亟待解决的现实难题.纳米药物主要由活性药物分子和递送系统(即药物载体)组成,是纳米材料或纳米颗粒在医学中最新发展起来的应用形式.由于其颗粒

Primary study on trans-activation ability of hepatitis B virus envelope proteins

目的构建系列含乙型肝炎病毒(HBV)表面抗原前-前-S区的酵母细胞表达质粒,初步探讨表达蛋白是否具有反式激活作用。方法用多聚酶链反应(PCR)扩增含前-前-S区的全S、S2和S基因,定向克隆于pDEST32载体,进行序列测定,重组质粒命名为pDEST32-wS、pDEST32-pS2和pDEST32-SHBs。用乙酸锂转化法将重组质粒转化酵母菌MaV203,经Western blot和胶体金法验证重组质粒在酵母细胞中的表达。以酵母双杂交法将重组质粒和载体pDEST22共同转入酵母菌MaV203,并在SC/-leu/-trp/-his三缺培养基及不同浓度梯度3AT培养基中验证自激活。结果重组质粒pDEST32-wS经序列测定含有HBV自前-前-S至主蛋白基因序列。经Western blot和胶体金法证实转染的酵母细胞可表达表面抗原蛋白。pDEST32-wS与pDEST22共转染实验证实被转染酵母细胞不能在浓度30 mmol/L以上的3AT培养基生存。结论构建了pDEST32-wS、pDEST32-pS2和pDEST32-SHBs表达载体,pDEST32-wS和pDEST32-SHBs在酵母细胞中可表达HBsAg... 【英文摘要】 Objective To construct yeast expression vector of HBV whole-S gene including pre-pre-S region and explore the trans-activation function of whole-S protein.Methods Whole-S gene,pre-pre-S to pre-S2 region and major HBsAg coding region containing Not I and Sal I endoenzyme sites were obtained by PCR method.After enzyme digestion,PCR products were cloned into yeast expression vector pDEST32.Recombinant plasmids were sequenced and named as pDEST32-wS,pDEST32-pS2 and pDEST32-SHBs,respectively.Recombinant plasmids...厦门市首批重大疾病科研攻关项目(WKZ0501);; 厦门市卫生局医学科研立项项目(WSK0506);; 厦门大学引进人才科研启动基金(Z03109);; 福建省青年科技人才创新项目(2006F3127);; 福建省青年科技人才创新项目(2006F3127

Expression and test of the neutralization Fab antibody against infectious bursal disease virus

为表达抗鸡传染性法氏囊病病毒(IbdV)抗体fAb并检测其中和活性,本研究将抗IbdV抗体的轻链(l)和重链片段(fd)基因分别克隆于P ET-27b(+)载体中,并转化于大肠杆菌rOSETTA(dE3)进行诱导表达。将l和fd片段包涵体蛋白变性后等量混合于复性液中,制备fAb并对其进行活性鉴定。结果显示l和fd蛋白相对分子质量大小分别为25 ku和28 ku。WESTErn blOT和ElISA检测结果表明,获得的抗体fAb大小约为50 ku,并且与VP2蛋白和不同病毒株均具有特异性结合能力。体外中和试验结果表明,获得的IbdV抗体fAb具有中和活性,可以有效阻断IbdV(b87株)对鸡胚成纤维细胞(df1)的感染。本实验获得的IbdV抗体fAb有望成为治疗Ibd的候选生物制剂,为研制治疗Ibd抗体制剂奠定了基础。To express the neutralizing Fab antibody against infectious bursal disease virus(IBDV),the gene of light chain(L)or heavy chain fragment(Fd) against IBDV was cloned into the prokaryotic expression plasmid,respectively,and then the recombinant L or Fd was expressed in E.coli Rosetta(DE3),respectively,and purified through sole denaturation and co-renaturation of inclusion body.Western blot results showed that the Fab was approximately 50 ku.ELISA results showed that the Fab exhibited binding ability and specify to VP2 for different IBDV strains.The results of neutralization test in vitro showed that the Fab exhibited neutralizing activity to IBDV-B87 strainin chicken embryo fibroblast(DF1) cells.The Fab antibody prepared in this study is expected to become a candidate drug for treatment of IBD,which laid the foundation for the treatment of IBD.黑龙江省应用技术研究与开发计划项目(GC13C104

社会系统工程与国家治理体系现代化

2014年3月30日,中国人民大学国家发展与战略研究院社会系统工程研究中心成立暨“社会系统工程与国家治理体系现代化“学术研讨会在中国人民大学逸夫会堂第一会议室举行,来自十余所高校和学术团体的专家、学者和一些媒体的代表参加了会议。现把会议主要发言内容选载如下

In-situ SERS of formic acid electro-catalytic oxidation on Au-core@Pt-shell/Pt electrode

Au-core@Pt-shell nanoparticles were synthesized by chemical reduction method. The samples were characterized by scanning electron microscope (SEM) and X-ray diffraction (XRD). In-situ surfac-enhanced Raman scattering (in-situ SERS) spectroscopy combined with cyclic voltammetry was utilized to investigate the electro-oxidation behavior of formic acid adsorbed on Au-core@Pt-shell nanoparticles coated on platinum electrode, and SERS spectra with high quality were acquired. Results showed that the intermediates COad and HCOOad, the dissociated products of HCOOH, were produced at open circuit potential. As the potential moved to positive, the first oxidation wave for CO, was observed at +0.10 V. The study demonstrated that the electrode prepared by Au-core@Pt-shell nanoparticles coated on platinum substrate exhibited good electro-catalytic properties and SERS activity for the oxidation of HCOOH, and the electro-oxidation proceeds of formic acid via "dual path" mechanism