4 research outputs found
Determinants of Psychosocial Difficulties Experienced by Persons with Brain Disorders: Towards a 'Horizontal Epidemiology' Approach
Background Persons with brain disorders experience significant psychosocial difficulties (PSD) in daily life, e.g. problems with managing daily routine or emotional lability, and the level of the PSD depends on social, physical and political environments, and psychologic-personal determinants. Our objective is to determine a brief set of environmental and psychologic-personal factors that are shared determinants of PSD among persons with different brain disorders. Methods Cross-sectional study, convenience sample of persons with either dementia, stroke, multiple sclerosis, epilepsy, migraine, depression, schizophrenia, substance dependence or Parkinson's disease. Random forest regression and classical linear regression were used in the analyses. Results 722 subjects were interviewed in four European countries. The brief set of determinants encompasses presence of comorbidities, health status appraisal, stressful life events, personality changes, adaptation, self-esteem, self-worth, built environment, weather, and health problems in the family. Conclusions The identified brief set of common determinants of PSD can be used to support the implementation of cross-cutting interventions, social actions and policy tools to lower PSD experienced by persons with brain disorders. This set complements a recently proposed reliable and valid direct metric of PSD for brain disorders called PARADISE24
Understanding the impact of brain disorders: Towards a 'horizontal epidemiology' of psychosocial difficulties and their determinants
Objective
To test the hypothesis of ‘horizontal epidemiology’, i.e. that psychosocial difficulties (PSDs),
such as sleep disturbances, emotional instability and difficulties in personal interactions,
and their environmental determinants are experienced in common across neurological and
psychiatric disorders, together called brain disorders.
Study Design
A multi-method study involving systematic literature reviews, content analysis of patientreported
outcomes and outcome instruments, clinical input and a qualitative study was
carried out to generate a pool of PSD and environmental determinants relevant for nine different
brain disorders, namely epilepsy, migraine, multiple sclerosis, Parkinson’s disease,
stroke, dementia, depression, schizophrenia and substance dependency. Information from
these sources was harmonized and compiled, and after feedback from external experts, a
data collection protocol including PSD and determinants common across these nine disorders
was developed. This protocol was implemented as an interview in a cross-sectional
Objective
To test the hypothesis of ‘horizontal epidemiology’, i.e. that psychosocial difficulties (PSDs),
such as sleep disturbances, emotional instability and difficulties in personal interactions,
and their environmental determinants are experienced in common across neurological and
psychiatric disorders, together called brain disorders.
Study Design
A multi-method study involving systematic literature reviews, content analysis of patientreported
outcomes and outcome instruments, clinical input and a qualitative study was
carried out to generate a pool of PSD and environmental determinants relevant for nine different
brain disorders, namely epilepsy, migraine, multiple sclerosis, Parkinson’s disease,
stroke, dementia, depression, schizophrenia and substance dependency. Information from
these sources was harmonized and compiled, and after feedback from external experts, a
data collection protocol including PSD and determinants common across these nine disorders
was developed. This protocol was implemented as an interview in a cross-sectionalThe PARADISE project is supported by the
Coordination Theme 1 (Health) of the European
Community’s FP7, Grant Agreement No. HEALTHF2-
2009-241572
Additional file 1: of Disability and recovery in schizophrenia: a systematic review of cognitive behavioral therapy interventions
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