500 KW Rüzgar Türbini İçin Ana Şaft Tasarımı Ve Analizi

Konferans Bildirisi -- Teorik ve Uygulamalı Mekanik Türk Milli Komitesi, 2013Conference Paper -- Theoretical and Applied Mechanical Turkish National Committee, 2013Bu çalışmada, 500 kW güç üreten bir rüzgar türbinin ana şaftının tasarımı ve yapısal analizleri yapılmıştır. Ana şaftın boyutlandırılmasında yorulma kriterlerinin esas alınması gerekmektedir. Ana şaftın yorulmaya ait yük durumu ise literatürde bulunan ampirik formüller kullanılarak hesaplanmıştır. Yorulma analizlerinde şaftı çevrimsel yüklerle zorlayan rotor ağırlığının yanında rüzgar kesmesi ve kule blokaj etkisi vb. sebeplerle ortaya çıkan değişken eğilme momenti ve tork değerleri de hesaba katılmıştır. Ana şaftın kritik kesitlerindeki çap hesabı, ASME Eliptik yorulma kriteri kullanılarak sonsuz ömre göre yapılmıştır. Ana şaftın tasarımındaki kritik bölgeler şaftın yataklandığı bölge ve şaftın dişli kutusuna bağlandığı bölgedir. Ayrıca, kontrol amaçlı olarak Uluslararası Elektroteknik Komisyonu’nun (International Electrotechnical Commision) yayınlamış olduğu IEC 64100-1 standardında belirtilen yükleme şartları için ana şaftın statik analizleri ANSYS 14.5 sonlu elemanlar yazılımı kullanılarak gerçekleştirilmiştir. Şaftın sonlu eleman modeli SOLID185 elemanlar kullanılarak oluşturulmuştur. Ayrıca, ana şaft - göbek bağlantı elemanlarının analizi de bu çalışma kapsamında yapılmıştır. Sayısal ve analitik yöntemler kullanılarak elde edilen deformasyon ve gerilme sonuçları karşılaştırılmış ve iyi bir uyum olduğu görülmüştür.In this paper, the main shaft which is one of the important structural parts for a 500 kW wind turbine has been designed. The fatigue criteria has been based on sizing the main shaft. The main shafts critic desing loads have been calculated by empirical formulas which are on the literatures. Oscillation moments of the torque and the flexural moments which is created by wind share, and effect of tower, etc. have been envisaged for analytical and numerical studies. In this study, the main shaft has been designed for infinite life using with ASME Elliptic criteria. There are two critic areas which are supported and connected to the gear box. In addition Iternational Electrotechnical Commision (IEC) 64100-1 standards have been based on the critic design load cases. The main shaft and the fasteners are modeled using the finite element method. The finite element model of the shaft is designed using with SOLID185 elements. Its static analysis have been achieved with using ANSYS 14.5 software. Also a comparison of two different approximations have been mentioned in this paper. The values of analitic and numerical of deplacement and stress are compared each

İleri kademe bazı ekmeklik buğday (Triticum aestivum L.) Genotiplerinin yağışa dayalı şartlarda tane verimi ve bazı kalite parametreleri yönünden değerlendirilmesi

Bu araştırma, 2013-2014 yetiştirme döneminde ileri kademe bazı ekmeklik buğday genotiplerinin taneverimi ve bazı kalite parametrelerinin belirlenmesi amacıyla yürütülmüştür. Araştırma materyali; Bahri DağdaşUluslararası Tarımsal Araştırma Enstitüsünce yürütülen ıslah çalışmaları kapsamında bölge verimkademesinde yer alan 14 hat ve 6 standart çeşitten oluşmaktadır. Çalışma 9 çevrede (Konya, İçeriçumra,Gözlü, Koçaş, Karaman, İkizce, Malya, Eskişehir, Hamidiye) Tesadüf Blokları Deneme Deseninde 4 tekerrürlüolarak yürütülmüş, kalite parametreleri Konya ve İçeriçumra çevrelerinde 2 tekerrürlü olarak elde edilmiştir.Çalışmada tane verimi (kg/da), bintane ağırlığı (g), protein (%) ve Zeleny sedimentasyon (ml) özellikleriincelenmiştir. Çevre ortalamaları değerlendirildiğinde tane verimi bakımından en yüksek değer 383 kg/da ileMalya'dan, en düşük değer 114 kg/da ile Hamidiye'den elde edilmiştir. Çalışmadaki tüm genotipler 9 çevredetane verimi bakımından değerlendirildiğinde en yüksek değer 269 kg/da ile hat15'den elde edilirken en düşükdeğer 171 kg/da ile hat17'den elde edilmiştir. Denemede ele alınan kalite parametrelerinden bin dane ağırlığı27.4-38.2 g arasında, protein oranı %12.26-14.80 arasında ve Zeleny sedimentasyon 34.7-57.2 ml arasındadeğişim göstermiştir. İncelenen özellikler bakımından kontrol çeşitler ve diğer hatlardan daha üstün özellikgösteren 1 adet hat, aday çeşit olarak Tohumluk Tescil ve Sertifikasyon Merkez Müdürlüğüne başvurusuyapılmış ve tescil denemelerine aktarılmıştır.Research materials are consist of the scope of breeding studies by Bahri Dağdaş International AgriculturalResearch Institute's 14 lines and 6 varieties from Regional yield trial. Study carried out at 9 environment(Konya, İçericumra, Gözlü, Koçaş, Karaman, İkizce, Malya, Eskişehir & Hamidiye) with randomized blockpattern in 4 replications, quality parameters recieved from Konya & İçeriçumra environment with 2 replication.The study grain yield (kg/ha), thousand kernel weight (g), protein (%) and Zeleny sedimentation (mL)properties were investigated. The highest average grain yield in terms of environmental value as assessed383 kg / ha with the Malya; were the lowest, 114 kg / ha were obtained by the Hamidiye. With regard to grainyield in all 9 genotypes at the study highest value around 269 kg / ha from the line 15 while the lowest value171 kg / ha were obtained from the 17 line. The quality parameters of the experiment discussed in thousandgrain weight between 27.4-38.2 g, 12.26-14.80% protein content ranged between and Zeleny sedimentationbetween 34.7-57.2 mL. When the control varieties and the other lines one line showed superior characteristicsand we applied this line as a candidate to Variety Registration and Seed Certification Center and wastransferred to registration trials

Efficacy of subsequent treatments in patients with hormone-positive advanced breast cancer who had disease progression under CDK 4/6 inhibitor therapy.

Background There is no standard treatment recommended at category 1 level in international guidelines for subsequent therapy after cyclin-dependent kinase 4/6 inhibitor (CDK4/6) based therapy. We aimed to evaluate which subsequent treatment oncologists prefer in patients with disease progression under CDKi. In addition, we aimed to show the effectiveness of systemic treatments after CDKi and whether there is a survival difference between hormonal treatments (monotherapy vs. mTOR-based). Methods A total of 609 patients from 53 centers were included in the study. Progression-free-survivals (PFS) of subsequent treatments (chemotherapy (CT, n:434) or endocrine therapy (ET, n:175)) after CDKi were calculated. Patients were evaluated in three groups as those who received CDKi in first-line (group A, n:202), second-line (group B, n: 153) and >= 3rd-line (group C, n: 254). PFS was compared according to the use of ET and CT. In addition, ET was compared as monotherapy versus everolimus-based combination therapy. Results The median duration of CDKi in the ET arms of Group A, B, and C was 17.0, 11.0, and 8.5 months in respectively; it was 9.0, 7.0, and 5.0 months in the CT arm. Median PFS after CDKi was 9.5 (5.0-14.0) months in the ET arm of group A, and 5.3 (3.9-6.8) months in the CT arm (p = 0.073). It was 6.7 (5.8-7.7) months in the ET arm of group B, and 5.7 (4.6-6.7) months in the CT arm (p = 0.311). It was 5.3 (2.5-8.0) months in the ET arm of group C and 4.0 (3.5-4.6) months in the CT arm (p = 0.434). Patients who received ET after CDKi were compared as those who received everolimus-based combination therapy versus those who received monotherapy ET: the median PFS in group A, B, and C was 11.0 vs. 5.9 (p = 0.047), 6.7 vs. 5.0 (p = 0.164), 6.7 vs. 3.9 (p = 0.763) months. Conclusion Physicians preferred CT rather than ET in patients with early progression under CDKi. It has been shown that subsequent ET after CDKi can be as effective as CT. It was also observed that better PFS could be achieved with the subsequent everolimus-based treatments after first-line CDKi compared to monotherapy ET

SARS-CoV-2 seropositivity among pediatric health care personnel just after the first peak of pandemic: A nationwide surveillance.

BACKGROUND: COVID-19 pandemic affected every single person on earth one way or the other. The healthcare personnel were no exception, their responsibilities as well as their risks being immense. METHODS: 4927 healthcare personnel all working in pediatric units at 32 hospitals from seven different regions of Turkey enrolled to the study to determine the seroprevalence of SARS Co-V-2 after the first peak wave. Point of care serologic lateral flow rapid test kit for IgM/IgG was used (Ecotest CE Assure Tech. Co. Ltd.). Seroprevalence and its association with demographic characteristics and possible risk factors were analyzed. RESULTS: Nearly 6.1% of healthcare personnel were found to be seropositive for SARS Co-V- 2. Seropositivity was more common among those who did not universally wear protective masks (10.6% vs 6.1%). Having a COVID-19 co-worker increased the likelihood of infection. The least and the most experienced personnel affected more. Most of the seropositive healthcare personnel (68%) did not have any suspicion that they had COVID-19 previously. CONCLUSIONS: Health surveillance for healthcare personnel involving routine point-of-care nucleic acid testing as well as monitoring PPE adherence would be important strategies to protect healthcare personnel from COVID-19 and to reduce nosocomial SARS-CoV-2 transmission

Evaluation of vaccination status of health care workers for recommended vaccines and their acceptance of SARS-CoV-2 vaccines

© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.Introduction: Health care workers (HCWs) are disproportionately exposed to infectious diseases and play a role in nosocomial transmission, making them a key demographic for vaccination. HCW vaccination rates are not optimal in many countries; hence, compulsory vaccination policies have been implemented in some countries. Although these policies are effective and necessary under certain conditions, resolving HCWs’ hesitancies and misconceptions about vaccines is crucial. HCWs have the advantage of direct contact with patients; hence, they can respond to safety concerns, explain the benefits of vaccination, and counter antivaccine campaigns that escalate during pandemics, as has been observed with COVID-19. Method: A short survey was carried out in May–June 2020 on the vaccination status of HCWs working with pediatric patients with COVID-19. The survey inquired about their vaccination status (mumps/measles/rubella [MMR], varicella, influenza, and diphtheria/tetanus [dT]) and willingness to receive hypothetical future COVID-19 vaccines. The respondents were grouped according to gender, age, occupation, and region. Results: In total, 4927 HCWs responded to the survey. Most were young, healthy adults. The overall vaccination rates were 57.8% for dT in the past 10 years, 44.5% for MMR, 33.2% for varicella, and 13.5% for influenza. Vaccination rates were the highest among physicians. The majority of HCWs (81%) stated that they would be willing to receive COVID-19 vaccines. Conclusion: Although vaccination rates for well-established vaccines were low, a majority of HCWs were willing to receive COVID-19 vaccines when available. Education and administrative trust should be enhanced to increase vaccination rates among HCWs