207 research outputs found

    REVIEWING THE EFFECT OF PLYOMETRICS TRAINING PERFORMED BY ICEMEN PLAY IN SUPER LEAGUE ON QUICK POWER AND MAXIMAL POWER

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    This study is planned to review the effect of the plyometrics training performed by icemen on the Dominant and Nondominant leg concentric and isokinetic power values at angular speed. Totally 14 male icemen, the age average of training group is (21,42±4,79), control group’s age average is (21,12±3,44). After being measured the knee extension and flexion, concentric isokinetic power properties, the athletes were divided into two groups as  control and training groups so as to be seven people in each of them by the random  method. The data obtained are analyzed by Mann Whitney-U and Wilcoxon Signed tests by computing the descriptive statistics in SPSS 16 program. While the control group was performing ice hockey for three days a week for eight weeks, the training group was performing the plyometrics training in addition to the same technical training. There is found a significant difference (p<0.05) between 60 deg/sec, 180 deg/sec and 300 deg/sec dominant leg extensor concentric and isokinetic powers. Even though there is a numerical increase between 60 deg/sec, 180 deg/sec, and 300 deg/sec dominant leg flexor concentric and isokinetic powers, no statistically significant difference is determined (p>0.05). A numerical increment is found in 60 dec/sec, 180 dec/sec and 300 dec/sec nondominant leg extensor concentric and isokinetic power. However, there is not seen any statistical enhancement in nondominant leg extensor concentric and isokinetic powers in spite of the numerical increase as 60 dec/sec,  180 dec/sec and 300 dec/sec.  Article visualizations

    Lycopene partially reverses symptoms of diabetes in rats with streptozotocin-induced diabetes

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    This study was supported in part by the Eskisehir Osmangazi University, the Scientific Research and Application Centre (FBAM). The authors are grateful to TICAM (Medical and Surgical Experimental Research Center, Eskisehir Osmangazi University)In the present study, we describe the effects of lycopene on the symptoms of streptozotocin (STZ)–induced diabetes in rats. Lycopene at the dose of 2.5 mg/kg body weight (bw) per day was orally administered to STZ-induced diabetic rats for a period of 7 days after onset of diabetes. At the same time, food–water intake and body weight change were recorded daily. Upon sacrifice, biochemical parameters, such as the serum glucose, insulin, total cholesterol (TC), triglyceride (TG), alanine aminotransferase (ALT), and aspartate aminotransferase (AST), were measured in all experimental groups. Administration of lycopene at the dose of 2.5 mg/kg bw per day significantly reduced serum glucose, TC, TG, ALT, and AST levels, and increased serum insulin levels, but there were no improvements in food–water intake and body weight change parameters in lycopene-treated diabetic rats. The results suggest that orally administrated lycopene exhibits a potent hypoglycemic effect in STZ-induced diabetic rats and that lycopene may be useful for the management of diabetes mellitus

    Investigación de la Contribución de la Instrucción Diferenciada en la Alfabetización de la Ciencia

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    The aim of this study is to reveal contributions of the differentiated instruction implemented in the primary school 4th grade science course into science literacy levels of the students. The case study method among qualitative research methods were used in the study. The research was carried out in the second term of 2015-2016 academic year. The study group consisted of the 4th grade students (n=23, 9-10 aged) studying in the Kozabirlik Primary State School in Bilecik city center in Turkey. Interviews (teachers and students), observations and student diary forms were administrated as data collection tools in the study. The content analysis method was implemented in the analysis of the obtained data. It was concluded from the findings that the differentiated instruction improved involvements of the students with the science-technology-society and the environment and developed their scientific process skills and thus contributed to the science literacy levels of the students.El objetivo de este estudio es dar a conocer las contribuciones de la instrucción diferenciada implementado en la escuela primaria 4º curso de grado de la ciencia en la ciencia en los niveles de alfabetización de los estudiantes. El método de estudio de caso, entre los métodos de investigación cualitativa se utilizaron en el estudio. La investigación se llevó a cabo en el segundo término del año académico 2015-2016. El grupo de estudio consistió de los estudiantes de 4º grado (n=23, 9-10 años) que estudia en la Kozabirlik Estatales de Primaria de la Escuela en Bilecik centro de la ciudad en Turquía. Entrevistas (maestros y estudiantes), observaciones y estudiante de diario de formas fueron administrados como herramientas de recolección de datos en el estudio. El análisis de contenido de método fue aplicado en el análisis de los datos obtenidos. De los hallazgos se concluyó que la instrucción diferenciada mejoró las implicaciones de los estudiantes con la ciencia-tecnología-sociedad y el medio ambiente y desarrolló sus habilidades de proceso científico y por lo tanto contribuyó a los niveles de alfabetización científica de los estudiantes

    Differentiating gastrointestinal stromal tumors from leiomyomas using a neural network trained on endoscopic ultrasonography images

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    Background: Endoscopic ultrasonography (EUS) is crucial to diagnose and evaluate gastrointestinal mesenchymal tumors (GIMTs). However, EUS-guided biopsy does not always differentiate gastrointestinal stromal tumors (GISTs) from leiomyomas. We evaluated the ability of a convolutional neural network (CNN) to differentiate GISTs from leiomyomas using EUS images. The conventional EUS features of GISTs were also compared with leiomyomas. Patients and Methods: Patients who underwent EUS for evaluation of upper GIMTs between 2010 and 2020 were retrospectively reviewed, and 145 patients (73 women and 72 men; mean age 54.8 ± 13.5 years) with GISTs (n = 109) or leiomyomas (n = 36), confirmed by immunohistochemistry, were included. A total of 978 images collected from 100 patients were used to train and test the CNN system, and 384 images from 45 patients were used for validation. EUS images were also evaluated by an EUS expert for comparison with the CNN system. Results: The sensitivity, specificity, and accuracy of the CNN system for diagnosis of GIST were 92.0%, 64.3%, and 86.98% for the validation dataset, respectively. In contrast, the sensitivity, specificity, and accuracy of the EUS expert interpretations were 60.5%, 74.3%, and 63.0%, respectively. Concerning EUS features, only higher echogenicity was an independent and significant factor for differentiating GISTs from leiomyomas (p < 0.05). Conclusions: The CNN system could diagnose GIMTs with higher accuracy than an EUS expert and could be helpful in differentiating GISTs from leiomyomas. A higher echogenicity may also aid in differentiation

    The hepatoprotective effects of Hypericum perforatum L. on hepatic ischemia/reperfusion injury in rats

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    Little is known about the effective role of Hypericum perforatum on hepatic ischemia-reperfusion (I/R) injury in rats. Hence, albino rats were subjected to 45 min of hepatic ischemia followed by 60 min of reperfusion period. Hypericum perforatum extract (HPE) at the dose of 50 mg/kg body weight (HPE50) was intraperitonally injected as a single dose, 15 min prior to ischemia. Rats were sacrificed at the end of reperfusion period and then, biochemical investigations were made in serum and liver tissue. Liver tissue homogenates were used for the measurement of malondialdehyde (MDA), catalase (CAT) and glutathione peroxidase (GPx) levels. At the same time alanine aminotransferase (ALT), aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) were assayed in serum samples and compared statistically. While the ALT, AST, LDH activities and MDA levels were significantly increased, CAT and GPx activities significantly decreased in only I/R-induced control rats compared to normal control rats (p < 0.05). Treatment with HPE50 significantly decreased the ALT, AST, LDH activities and MDA levels, and markedly increased activities of CAT and GPx in tissue homogenates compared to I/R-induced rats without treatment-control group (p < 0.05). In oxidative stress generated by hepatic ischemia-reperfusion, H. perforatum L. as an antioxidant agent contributes an alteration in the delicate balance between the scavenging capacity of antioxidant defence systems and free radicals in favour of the antioxidant defence systems in the body

    Gallic acid reduces experimental colitis in rats by downregulation of cathepsin and oxidative stress

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    Objective: Ulcerative colitis (UC) is an idiopathic inflammatory bowel disease (IBD) with common, repetitive inflammation of the colon and rectum, which is highly defined by loss of blood on colon mucosa, ulceration and acute inflammation. The present study aimed to investigate the potential protective effects of gallic acid (GA) through a 2,4,6-trinitrobenzene sulfonic acid (TNBS)-induced colitis rat model, using biochemical and histopathological parameters. Materials and Methods: The study consisted of four groups, each including seven rats, namely control group, colitis group, colitis-GA 50 mg/kg group and colitis-GA 100 mg/kg group. Colon tissue samples were analyzed for malondialdehyde (MDA), myeloperoxidase (MPO), cathepsin B and cathepsin L values. Results: Tissue MDA, MPO, cathepsin L and cathepsin B values increased significantly in colitis group (p=0.028, p=0.038, p=0.024, p=0.019, respectively). However, MDA, MPO, cathepsin L and cathepsin B values showed a significant decrease in animals with GA (at a dose of 100 mg/kg) administration in TNBS-induced colitis in rats (p=0.021, p=0.026, p=0.019, p=0.031, respectively). Colitis group was defined by the severe detriment of surface epithelium, submucosal edema and inflammatory cell infiltration. Treatment with GA significantly decreased inflammatory cell infiltration. Conclusion: GA can be used as an effective agent in the treatment of colitis due to its inhibitory properties in multiple pathways and its potent antioxidant effect

    The examination of protective effects of gallic acid against damage of oxidative stress during induced-experimental renal ischemia-reperfusion in experiment

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    Aim: In this study, probable effects of gallic acid were investigated in experimentally induced renal I/R injury in rats. Material and methods: For this purpose, each group consisted of 7 Sprague dawley male albino rats. Groups were defined as follows; Group I: control group; Group II: I/R group; Group III, IV and V: I/R+Gallic acid (50, 100 and 200 mg.kg(-1) respectively-i.p.). Left kidney was removed by nephrectomy except for Group I. I/R was induced in the other kidney. Gallic acid was given 15 mins before ischemia induction. SOD, CAT and Gpx activities were determined by electrophoresis. MDA, MPO levels were determined spectrophotometrically. Histopathological investigations were also performed in kidney tissues. BUN and Creatinine levels in serum were determined. Results: BUN, Creatinine and MDA levels were statistically significant but MPO level was not statistically significantly increased in Group II. For SOD, CAT, Gpx activities in Group II, an increase was determined with respect to Group I. Histopathological investigations revealed widespread hyperemia in glomerulus, expansion of the structure between tubules and cell disruptions in Group II. In Group V (200 mg.kg-1 gallic acid), in terms of biochemical parameters, in spite of the significant decrease in BUN, Creatinine and MDA levels; a decrease was determined in SOD, CAT and Gpx isoenzyme activities. Group V showed histologically that I/R injury had been prevented to a greater extent and appearances were close to the control. Conclusion: As a result, in terms of our study, evaluations regarding kidney functions and histopathology have shown that gallic acid has protective effects in renal I/R injury (Tab. 2, Fig. 5, Ref. 36). Text in PDF www.elis.sk

    Utilización del documento de consentimiento informado en la práctica odontológica pública del partido de La Plata (Argentina) - 2003

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    La odontología como ciencia biológica difiere del pensamiento jurídico en numerosos puntos. La biología es a menudo variante. Por lo tanto el razonamiento biológico lleva implícito una parte de reserva, de incertidumbre y de duda. Por el contrario el pensamiento jurídico tiene que responder a los textos que lo instituyen como los códigos y las leyes, que son de elaboración humana, por lo tanto discernibles y asimilables. Desde la época que el hombre realizaba investigaciones empíricas, hasta nuestros días, han concurrido ciencias y disciplinas de investigación que han generado el crecimiento de diferentes especialidades, aportando elementos que definen y caracterizan su campo de acción. La Odontología Legal, como cualquier rama de la ciencia, es un producto de la evolución del hombre. Por lo tanto varía con el tiempo, es distinta según los estados o los países. El Derecho moderno establece una colaboración entre la ciencia y la ley. En estos casos el grado de responsabilidad del odontólogo es alto, porque tiene la función de auxiliar con sus conocimientos, donde sus dichos pueden influir con fuerza sobre el fallo del magistrado. Es preciso, actualmente que el perito odontólogo, adquiera un cúmulo de conocimientos sobre el espíritu jurídico y los procedimientos a seguir en los distintos fueros.Facultad de Odontología (FOLP
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