Two Cases of Hidradenitis Suppurativa Treated with Adalimumab at the Department of Dermatology and Venereology, Clinical Hospital Mostar

Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease primarily affecting apocrine gland-rich areas of the body and presenting with painful nodules, abscesses, sinus tracts, and scarring (1). HS is a defect of the follicular epithelium; some have therefore called for the naming the disease acne inversa instead of hidradenitis suppurativa. The term acne inversa links the pathogenesis to acne and reflects the fact that it is an expression of follicular occlusion in localizations inverse to acne vulgaris (2)

Synthesis and testing of the electro-catalytic materials for the hydrogen-peroxide reduction

In this paper, the synthesis, characterization and electrochemical testing of carbon material (graphene) modified with the Pd nanoparticles in the hydrogen peroxide reduction reaction was performed. Graphene was synthesized from glucose as a precursor, using FeCl3 as a catalyst. The reduction of hydrogen peroxide on the synthesized material was studied by the cyclic voltammetry and square wave voltammetry

Methods of Pollution Removal After Tanker “Erika” Accident

Marine accident of the Maltese tanker Erika is the biggest environmental disaster ever to hit France. 12th of December 1999, on the way from Dunkerque (France) to Livorno (Italy), Erika broke in two and sank near the French coast, spilling around 20.000 tons of heavy fuel oil into the sea. About 11.000 tons of dangerous cargo, trapped inside the sunken wreck, presented a danger to the environment. Severe weather conditions prevented any offshore clean-up operations. Oil trapped inside the wreckage was pumped out, while the on-shore clean-up operations lasted for another two years. This accident had a direct impact on the economy of affected regions and resulted in numerous lawsuits against the ship owners, charterers and classification societies. This paper aims to provide an overview of oil spill pollution clean-up methods and technologies after the accident of tanker Erika

Hitni EEG i dijagnostički doprinos

The aim of the study was to determine whether an acute loss of consciousness, mental status change or related symptoms correlated with the presence of epileptiform abnormalities on urgent EEG. We analyzed 228 consecutive patients admitted to Emergency Room during the past 12 months and referred for urgent EEG evaluation. All patients had either a brief loss of consciousness or acute brain disorder, with a clinical diagnosis of epilepsy, syncope, head trauma, headache, transient ischemic attack (TIA) or vertigo. Statistical analysis was performed using Spearman\u27s rho test for group comparison and multivariate regression analysis. The mean age of patients was 48±20 years. The frequency of referring clinical diagnoses was as follows: epilepsy 44.7% (102/228), TIA 15.8% (36/228), syncope 15.4% (35/228), headache 11%(25/228), vertigo 7.9% (18/228) and acute head trauma 5.3% (12/228). EEG indicated epileptiform abnormalities in 14.9%(34/228) and focalslowingin9.2%(21/228) of patients. The majority of them(26%;21/81) had a clinical diagnosis of epilepsy. There was a significant correlation between clinical diagnosis of epilepsy and epileptiform EEG (Spearman\u27s rho=0.13;P<0.04). Multivariate regression analysis showed that there was no predictive value in the clinical diagnosis of epilepsy and epileptiform EEG (ψ=1.483, P=0.16). In conclusion, epilepsy was the most common clinical diagnosis in patients referred for urgent EEG. There was a significant correlation between the diagnosis and specific EEG abnormalities, however, the diagnosis of epilepsy failed to predict epileptiform activity on EEG. Study results suggested urgent EEG to have a high yield in patients with epilepsy.Željeli smo utvrditi korelira li akutni gubitak svijesti, promjena psihološkog statusa ili s tim povezani simptomi s prisutnošću epileptiformnih nenormalnosti na hitnom EEG. Analizirali smo 228 susljednih bolesnika primljenih u Hitnu službu tijekom posljednjih 12 mjeseci, koji su upućeni na procjenu pomoću hitnog EEG. Svi bolesnici su imali kratak gubitak svijesti ili akutni moždani poremećaj uz kliničku dijagnozu epilepsije, sinkope, traume glave, glavobolje, prolaznog ishemijskog napada (TIA) ili vrtoglavice. U statističkoj analizi rabio se Spearmanov rho test za usporedbu skupina i multivarijatna regresijska analiza. Srednja dob bolesnika bila je 48±20 godina. Učestalost uputnih dijagnoza bila je kako slijedi: 44,7% (102/228) epilepsija; 15,8% (36/228) TIA; 15,4% (35/228) sinkopa; 11% (25/228) glavobolja; 7,9% (18/228) vrtoglavica i 5,3% (121228) akutna trauma glave. EEG je otkrio epileptiformne nenormalnosti u 14,9% (34/228) i žarišnu usporenost u 9,2% (21/228) bolesnika. Većina bolesnika (26%; 21/81) je imala kliničku dijagnozu epilepsije. Utvrđena je značajna korelacija između kliničke dijagnoze epilepsije i epileptiformnog EEG (Spearmanov rho 0,13; P=0,04). Multivarijatna regresijska analiza pokazala je kako klinička dijagnoza epilepsije i epileptiformni EEG nemaju nikakve prediktivne vrijednosti (ψ=1,483; P=0,16). Zaključili smo kako je epilepsija najčešća klinička dijagnoza u bolesnika upućenih na hitni EEG. Zabilježena je značajna korelacija između dijagnoze i specifičnih nenormalnosti na EEG, međutim, dijagnoza epilepsije nije predvidjela epileptiformnu aktivnost na EEG. Naši podaci ukazuju na to da hitni EEG ima visok rezultat u bolesnika s epilepsijom

Methods of Pollution Removal after Tanker “Erika” Accident

Marine accident of the Maltese tanker Erika is the biggest environmental disaster ever to hit France. 12th of December 1999, on the way from Dunkerque (France) to Livorno (Italy), Erika broke in two and sank near the French coast, spilling around 20.000 tons of heavy fuel oil into the sea. About 11.000 tons of dangerous cargo, trapped inside the sunken wreck, presented a danger to the environment. Severe weather conditions prevented any offshore clean-up operations. Oil trapped inside the wreckage was pumped out, while the on-shore clean-up operations lasted for another two years. This accident had a direct impact on the economy of affected regions and resulted in numerous lawsuits against the ship owners, charterers and classification societies. This paper aims to provide an overview of oil spill pollution clean-up methods and technologies after the accident of tanker Erika

ELECTROPHORETIC DEPOSITION AS AN EFFECTIVE AND SIMPLE PROCESSING TECHNIQUE FOR FABRICATION OF MAGNESIUM SILICATE HYDRATE (M-S-H) COATINGS ONTO STAINLESS STEEL SUBSTRATES

Magnesium silicate hydrate (M-S-H) was prepared via one-pot hydrothermal synthesis and electrophoretically deposited (EPD) onto stainless steel substrate (Type 304), varying different process parameters. The optimal conditions for the EPD process were found to be as follows. A stable suspension of material was achieved using isopropanol containing 1% water as dispersing medium and Mg-nitrate as charging additive. The best coating was obtained after three successively repeated EPD processes at a voltage of 30 V, accompanied by drying at room temperature between each EPD cycle. The coating showed a thickness of 31 µm and very smooth surface. After calcination at 900 °C coating retains its adherence to the substrate but undergoes a structural transformation from poorly crystallized M-S-H to well-crystallized clinoenstatite phase which is known for its biocompatibility. As a result, it densifies and shrinks giving grainy and slightly rough surface. Structural properties and parameters of the magnesium silicate hydrate (M-S-H) and clinoenstatite were acquired by XRD technique, while morphology was examined by the analysis of SEM micrographs. This study demonstrates that: i) M-S-H can be synthesized through simple hydrothermal route starting from simple, low-cost precursors, ii) EPD process is an effective technique for deposition of M-S-H materials onto stainless steel and iii) inosilicate mineral (clinoenstatite) can be successfully obtained from M-S-H by calcination at 900 °C. HIGHLIGHTSMagnesium silicate hydrate (M-S-H) was prepared via a one-pot hydrothermal synthesis.The optimal conditions for the electrolytic deposition process were determined.Kinetics of the process were investigated using the Hamaker`s equation.Clinoenstatite can be successfully obtained from M-S-H by calcination

Hitni EEG i dijagnostički doprinos

The aim of the study was to determine whether an acute loss of consciousness, mental status change or related symptoms correlated with the presence of epileptiform abnormalities on urgent EEG. We analyzed 228 consecutive patients admitted to Emergency Room during the past 12 months and referred for urgent EEG evaluation. All patients had either a brief loss of consciousness or acute brain disorder, with a clinical diagnosis of epilepsy, syncope, head trauma, headache, transient ischemic attack (TIA) or vertigo. Statistical analysis was performed using Spearman\u27s rho test for group comparison and multivariate regression analysis. The mean age of patients was 48±20 years. The frequency of referring clinical diagnoses was as follows: epilepsy 44.7% (102/228), TIA 15.8% (36/228), syncope 15.4% (35/228), headache 11%(25/228), vertigo 7.9% (18/228) and acute head trauma 5.3% (12/228). EEG indicated epileptiform abnormalities in 14.9%(34/228) and focalslowingin9.2%(21/228) of patients. The majority of them(26%;21/81) had a clinical diagnosis of epilepsy. There was a significant correlation between clinical diagnosis of epilepsy and epileptiform EEG (Spearman\u27s rho=0.13;P<0.04). Multivariate regression analysis showed that there was no predictive value in the clinical diagnosis of epilepsy and epileptiform EEG (ψ=1.483, P=0.16). In conclusion, epilepsy was the most common clinical diagnosis in patients referred for urgent EEG. There was a significant correlation between the diagnosis and specific EEG abnormalities, however, the diagnosis of epilepsy failed to predict epileptiform activity on EEG. Study results suggested urgent EEG to have a high yield in patients with epilepsy.Željeli smo utvrditi korelira li akutni gubitak svijesti, promjena psihološkog statusa ili s tim povezani simptomi s prisutnošću epileptiformnih nenormalnosti na hitnom EEG. Analizirali smo 228 susljednih bolesnika primljenih u Hitnu službu tijekom posljednjih 12 mjeseci, koji su upućeni na procjenu pomoću hitnog EEG. Svi bolesnici su imali kratak gubitak svijesti ili akutni moždani poremećaj uz kliničku dijagnozu epilepsije, sinkope, traume glave, glavobolje, prolaznog ishemijskog napada (TIA) ili vrtoglavice. U statističkoj analizi rabio se Spearmanov rho test za usporedbu skupina i multivarijatna regresijska analiza. Srednja dob bolesnika bila je 48±20 godina. Učestalost uputnih dijagnoza bila je kako slijedi: 44,7% (102/228) epilepsija; 15,8% (36/228) TIA; 15,4% (35/228) sinkopa; 11% (25/228) glavobolja; 7,9% (18/228) vrtoglavica i 5,3% (121228) akutna trauma glave. EEG je otkrio epileptiformne nenormalnosti u 14,9% (34/228) i žarišnu usporenost u 9,2% (21/228) bolesnika. Većina bolesnika (26%; 21/81) je imala kliničku dijagnozu epilepsije. Utvrđena je značajna korelacija između kliničke dijagnoze epilepsije i epileptiformnog EEG (Spearmanov rho 0,13; P=0,04). Multivarijatna regresijska analiza pokazala je kako klinička dijagnoza epilepsije i epileptiformni EEG nemaju nikakve prediktivne vrijednosti (ψ=1,483; P=0,16). Zaključili smo kako je epilepsija najčešća klinička dijagnoza u bolesnika upućenih na hitni EEG. Zabilježena je značajna korelacija između dijagnoze i specifičnih nenormalnosti na EEG, međutim, dijagnoza epilepsije nije predvidjela epileptiformnu aktivnost na EEG. Naši podaci ukazuju na to da hitni EEG ima visok rezultat u bolesnika s epilepsijom

Zašto se švedski jezik mijenja?

U ovom radu predstavljaju se teorije vezane za moguće uzroke promjena u jeziku. Opisuje se razlika između unutarnjih i vanjskih uzroka te se kratko dotiče rasprava o podjeli, ponajviše je li zapravo moguće jasno razdijeliti uzroke u jednu ili drugu kategoriju. U radu su jezične promjene podijeljene u one potaknute vanjskim čimbenicima, koje su rezultat sociolingvističkih fenomena, te one potaknute unutarnjim čimbenicima i koje proizlaze direktno iz jezičnog sistema. Prestiž, geografija i jezični kontakt navode se kao primjeri promjena potaknutih vanjskim čimbenicima, dok su pojednostavljivanje i popravljanje jezičnih obrazaca primjeri unutarnjih razloga promjene. Gdje je moguće, koncepti su ilustrirani primjerima iz švedskog jezika. Rad se također dotiče problema vezanih uz područje proučavanja jezičnih promjena kao što je nemogućnost dijakronijskog praćenja promjena te nedostatak materijala iz prošlosti jezika koji iz te nemogućnosti proizlazi.This paper aims to present theories about possible causes of language change. It describes the difference between internal and external causes and briefly mentions the debate around this dichotomy, namely if it is even possible to cleanly divide changes into one or the other. A short explanation of how changes come to be is also given. The changes are loosely grouped into those externally motivated which arise from sociolinguistic phenomena, and those internally motivated which stem from the language system itself. External reasons given are prestige, geography, and language contact, while internal are simplification and repairing of the patterns. Where possible, the causes are illustrated with examples from Swedish. The paper also touches upon issues surrounding the study of language change such as the inability to track the progress of the change and the subsequent lack of historical data and necessity of focusing primarily on written data

Entrepreneurial Strategic Orientation: Prerequisite for SMEs Success in IoT and Digital Transformation Sphere?

Entrepreneurial orientation (EO) is a multidimensional construct that reflects a firm’s tendency to be innovative, proactive, and risk-taking. Previous research has demonstrated that companies with a strong EO possess a competitive advantage in the market when compared to those with a conservative approach to management. The objective of this study is to analyse the entrepreneurial orientation of small and medium-sized enterprises (SMEs) using the ENTRE-U scale and to identify the dimensions of EO that are critical for achieving business success in the context of digital transformation and IoT implementation. The identification of these dimensions is facilitated through a survey method and exploratory factor analysis. After administering the ENTRE-U scale to a representative sample of SMEs that use modern technologies, such as IoT, four distinct dimensions of EO emerged. Each dimension of EO has a significant impact on firm performance. By adhering to the established EO dimensions and using the proposed methodology, managers can develop an efficient business model that aligns with the current digital market demands, enhances SMEs (survival, resilience, and sustainability), and addresses the high uncertainty prevalent in today’s business environment