235 research outputs found

    La tecnologia a l'educació STEM a infantil

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    RENEWABLE ENERGY SOLUTIONS FOR TOURISM

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    This study aimed to investigate the importance of renewable energy sources usage in tourism which has a significant market power in world economy. Tourism has a big contribution to regional development and also some cons on environmental issues. To reduce the negative aspects on environment and increase the financial savings of tourism industry, renewable energy has a vital priority. Renewable energy will align the hotel areas with concept of green tourism. Financial savings through this energy also has been provided in that study. This paper also suggests an analysis for suitable sources of renewable energy usage in hotels with a sample practice

    Risk Factors for Trabeculotomy Failure in Primary Congenital Glaucoma

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    Précis: This study demonstrates that a baseline corneal diameter >12.25, initial age [removed]12.25 mm did by 4.2 times, younger age than 4 months did by 2.5 times, bilaterality did by 1.5 times. Conclusions: A higher baseline IOP, younger age, larger corneal diameter, and bilaterality were identified as risk factors for trabeculotomy failure in congenital glaucoma. The presence of one or more of these should be considered in the decision-making process when considering surgical options to manage glaucoma in these patients. © 2022 Wolters Kluwer Health, Inc. All rights reserved

    Off-Label Drug Use in Patients with Age-Related Macular Degeneration in Turkey

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    Aim:To evaluate the demographic characteristics of patients who use off-label drugs for Age-related Macular Degeneration (AMD) in Turkey.Materials and Methods:The applications for off-label drug use in patients with AMD (bevacizumab, ranibizumab, aflibercept, verteporfin) from hospitals in Turkey to the Turkish Medicines and Medical Devices Agency from January to December 2013 were evaluated retrospectively. The files of the cases were evaluated in terms of demographic data, previous treatment regimens, reasons for application, dosage and usage of the drug.Results:This study included 64 patients who applied for off-label drug use under the diagnosis of AMD. The mean age of all patients was 70.12 ± 11.01 years and 46.9 % were male, 53.1 % were female. Of these, 39.1 % was ranibizumab, 29.7 % was verteporfin, 18.8 % was aflibercept, and 12.5 % was bevacizumab. Applications belonged to Ege (48.4%), Central Anatolia (23.4%), Marmara (25.0%) and East Anatolia (3.1%) regions. In the distribution of the referring hospitals, the first three hospitals were the state universities (48.4 %), the education and research hospitals (40.6%) and the foundation universities (7.8%) Of patients, twelve (18.8%) were naïve patients with no previous treatment regimen. Resistance to other anti-vascular endothelial growth factors as the cause of admission was in the 1st rank with 64.1%.Conclusion:In the treatment of AMD, determining the off-label drug application information and the actual records related to this subject will give us instructive information about our treatment options as well as its contribution to the literature
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