On the computation of finite bottom-quark mass effects in Higgs boson production

We present analytic results for the partonic cross-sections contributing to the top-bottom interference in Higgs production via gluon fusion at hadron colliders at NLO accuracy in QCD. We develop a method of expansion in small bottom-mass for master integrals and combine it with the usual infinite top-mass effective theory. Our method of expansion admits a simple algorithmic description and can be easily generalized to any small parameter. These results for the integrated cross-sections will be needed in the computation of the renormalization counter-terms entering the computation of finite bottom-quark mass effects at NNLO.Comment: Updated affiliations and abstract, added reference, and corrected minor typo

Computing decay rates for new physics theories with FeynRules and MadGraph 5_aMC@NLO

We present new features of the FeynRules and MadGraph 5_aMC@NLO programs for the automatic computation of decay widths that consistently include channels of arbitrary final-state multiplicity. The implementations are generic enough so that they can be used in the framework of any quantum field theory, possibly including higher-dimensional operators. We extend at the same time the conventions of the Universal FeynRules Output (or UFO) format to include decay tables and information on the total widths. We finally provide a set of representative examples of the usage of the new functions of the different codes in the framework of the Standard Model, the Higgs Effective Field Theory, the Strongly Interacting Light Higgs model and the Minimal Supersymmetric Standard Model and compare the results to available literature and programs for validation purposes

The attitudes of nursing students toward gay and lesbian ındividuals in Turkey: stigmatization

Aim: This study aims to investigate the attitudes of Turkish nursing students toward LGBT individuals and the influencing factors. Methods: This is a cross-sectional study. Three hundred and forty-eight nursing students from a public university in Turkey participated in this study. The data were collected using a Descriptive Information Form, Attitudes toward Lesbians and Gay Men (ATLG) Scale, Empathic Tendency Scale, and Stigmatization Scale. The study data were evaluated with independent T-test and one-way ANOVA using the SPSS Statistics 22 pack. Results: The results showed that the participating nursing students have negative attitudes toward LGBT individuals, with a significant correlation between their attitudes towards LGBT people and stigmatization tendencies (p<0.05). The multiple linear regression analysis showed that 14.3% (R2=0.143) of attitudes of the students toward such individuals can be attributed to emphatic and stigmatization tendencies. Conclusion: Since there is a gap in the literature regarding the issue, in Turkey, this study is important in that itinvestigates the factors that influence the attitudes of nursing students in particular toward lesbians and gay me

Views of senior nursing students on the problems of the elderly during the covid-19 process and attitudes against ageism

Background: Older adults, the prevalence of chronic diseases increase, depending on the physiological and psychological changes that occur with aging processes of maintenance issues in pandemic seems to be more important. Objectives: This study aims to examine the attitudes of senior nursing students regarding ageism as well as their views of the problems the elderly faced during the COVID-19 pandemic. Methods: The present study is a mixed study with quantitative and qualitative dimensions and it was conducted in a nursing school in X. The quantitative part of the research was conducted with 75 senior students, 13 of whom were also included in the qualitative part of the study. Quantitative data were collected using the Introductory Information Form and the Ageism Attitude Scale and qualitative data using a semi-structured interview form. Descriptive statistics, independent samples t-test, one-way analysis Mann–Whitney U, and Kruskal–Wallis tests and content analysis were used. Results: It was found that the students’ attitudes toward the elderly were positive and their views of the elderly during the pandemic were distributed among the main themes of Vulnerable, Emotional Shake, Culture, and Iceberg. Conclusion: it is believed that it is important to ensure that health team members who will work with the older adults should be provided with an environment wherein they can provide care to the older adults in the first years of their education

Monogenic Childhood Diabetes: Dissecting Clinical Heterogeneity by Next-Generation Sequencing in Maturity-Onset Diabetes of the Young

Diabetes is a common disorder with a heterogeneous clinical presentation and an enormous burden on health care worldwide. About 1-6% of patients with diabetes suffer from maturity-onset diabetes of the young (MODY), the most common form of monogenic diabetes with autosomal dominant inheritance. MODY is genetically and clinically heterogeneous and caused by genetic variations in pancreatic beta-cell development and insulin secretion. We report here new findings from targeted next-generation sequencing (NGS) of 13 MODY-related genes. A sample of 22 unrelated pediatric patients with MODY and 13 unrelated healthy controls were recruited from a Turkish population. Targeted NGS was performed with Miseq 4000 (Illumina) to identify genetic variations in 13 MODY-related genes: HNF4A, GCK, HNF1A, PDX1, HNF1B, NEUROD1, KLF11, CEL, PAX4, INS, BLK, ABCC8, and KCNJ11. The NGS data were analyzed adhering to the Genome Analysis ToolKit (GATK) best practices pipeline, and variant filtering and annotation were performed. In the patient sample, we identified 43 MODY-specific genetic variations that were not present in the control group, including 11 missense mutations and 4 synonymous mutations. Importantly, and to the best of our knowledge, the missense mutations NEUROD1 p.D202E, KFL11 p.R461Q, BLK p.G248R, and KCNJ11 p.S385F were first associated with MODY in the present study. These findings contribute to the worldwide knowledge base on MODY and molecular correlates of clinical heterogeneity in monogenic childhood diabetes. Further comparative population genetics and functional genomics studies are called for, with an eye to discovery of novel diagnostics and personalized medicine in MODY. Because MODY is often misdiagnosed as type 1 or type 2 diabetes mellitus, advances in MODY diagnostics with NGS stand to benefit diabetes overall clinical care as well