91 research outputs found
EVALUATION OF ANTIBACTERIAL, ANTITUMOR, ANTIOXIDANT ACTIVITIES AND PHENOLIC CONSTITUENTS OF FIELD-GROWN AND IN VITRO-GROWN LYSIMACHIA VULGARIS L.
Background: Lysimachia vulgaris L. (Yellow loosestrife) is a medicinal plant in the family Myrsinaceae. It has been used in the
treatment of fever, ulcer, diarrhea and wounds in folk medicine. It has also analgesic, expectorant, astringent and antiinflammatory
activities. Two different sources of the plant (field-grown and in vitro-grown) were used to evaluate the biological
activities (antibacterial, antitumor and antioxidant) of L. vulgaris. In vitro-grown plant materials were collected from L. vulgaris
plants that were previously regenerated in our laboratory.
Materials and Methods: Plant materials were extracted with water, ethanol and acetone. For antibacterial test, disc diffusion
method and 10 different pathogenic bacteria were used. Antioxidant activity was indicated by using DPPH method. The total
phenol amount by using Folin-Ciocaltaeu method and the total flavonoid amount by using aluminum chloride (AlCl3) colorimetric
method were determined.
Results: Generally, yellow loosestrife extracts demonstrated antibacterial activity against Gram-positive bacteria (Staphylococcus
aureus, S. epidermidis and Streptococcus pyogenes). Strong antitumor activity of yellow loosestrife was observed via potato disc
diffusion bioassay. Nine different phenolics were also determined and compared by using High-Performance Liquid
Chromatography (HPLC).
Conclusion: Future investigations should be focused on fractionation of the extracts to identify active components for biological
activity
BEST PRACTICE GUIDE: USE OF THERMAL IMAGERS TO PERFORM TRACEABLE NON-CONTACT SCREENING OF HUMAN BODY TEMPERATURE
Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries
Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P < 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely
Güngör, Y., Pehlivan R., 1998. İyidere Havzası Dere Sedimentlerinin Zr- Ti potansiyelinin belirlenmesi. Türkiye Cumhuriyetinin 75. Yılında Fırat Üniversitesinde Jeoloji Mühendisliği Eğitiminin 20. Yılı Sempozyumu Bildiri Özetleri Kitabı, s.102
Güngör, Y., Pehlivan, R., 1997. İyidere Havzası Dere sedimentlerinin Zr – Ti Potansiyelinin belirlenmesi. İ.Ü. Yer Bilimleri Dergisi, Cilt : 9, S. 1-2, s. 45- 55
POLİMER NANOKOMPOZİTLERDE NANO DOLGU DAĞILIMINA BAĞLI OLARAK DİELEKTRİK POLARİZASYON MEKANİZMALARININ İNCELENMESİ.
Güngör, Y., Pehlivan R., Yılmaz O., 1998. Jeolojik Etken Olarak İnsan. Türkiye Cumhuriyetinin 75. Yılında Fırat Üniversitesinde Jeoloji Mühendisliği Eğitiminin 20. Yılı Sempozyumu Bildiri Özetleri Kitabı, s.150
Güngör, Y., Yılmaz, O., Pehlivan, Y., 2003. Karadeniz Bölgesi Granitoyid kuşaklarına bağlı Zirkon- Titan Oluşumların belirlenmesi. 56. Türkiye Jeoloji Kurultayı Bildiri Özetleri Kitabı, s., 129- 130
Güngör, Y., Emre, H., Pehlivan R., 1998. İyidere Havzası Dere Sedimentlerindeki Zr - Ti Verilerinin Jeoistatistiksel değerlendirmesi. Türkiye Cumhuriyetinin 75. Yılında Fırat Üniversitesinde Jeoloji Mühendisliği Eğitiminin 20. Yılı Sempozyumu Bildiri Özetleri Kitabı, s.103
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