New Pre-Pottery Neolithic sites and cult centres in the Urfa Region

The present study assesses the sites and the corresponding artefacts that were recently discovered during cultural inventory studies in the Urfa region in south-eastern Turkey. The studies were conducted at PPN sites located at Herzo Tepe, Basaran Höyük and Kocanizam, Taslı Tepe and  ̇Inanlı Tepe within the borders of Viransehir and Siverek boroughs; the already known site at Sefer Tepe is also re-examined. The sites extend in a north-south direction and were founded within a 3–5km distance, and they exhibit unique characteristics for this region. Recently discovered sites are compared to already known PPN sites in the region to reveal similar features and characteristics. In particular, the article elaborates similarities and discrepancies between sites with T-shaped pillars and sites with circular structures. The recently discovered sites demonstrate that the pillar tradition is predominant in the region and that the settlements have a distinct layout.V študiji ovrednotimo najdišča in pripadajoče artefakte, ki so bili nedavno odkriti pri študijah kulturnih inventarjev v regiji Urfa na območju južno-vzhodne Turčije. Analize so bile opravljene na najdiščih predkeramičnega neolitika na območjih kot so Herzo Tepe, Basaran Höyük in Kocanizam, Taşlı Tepe in İnanli Tepe znotraj mestnih okrajev Viransehir in Siverek; ponovno smo preiskali tudi že znano najdišče Sefer Tepe. Najdišča se raztezajo v smeri sever-jug in so postavljena v razdalji od 3 do 5km, poleg tega pa izkazujejo edinstvene značilnosti za to območje. Nedavno odkrita najdišča primerjamo z že znanimi predkeramičnimi najdišči v regiji in na ta način ugotavljamo njihove podobnosti in značilnosti. V članku se podrobneje ukvarjamo s podobnostmi in razlikami med najdišči s stebri v obliki črke T in najdišči s krožnimi strukturami. Nedavno odkrita najdišča kažejo, da v tej regiji prevladuje tradicija stebrov in da imajo naselbine značilne prostorske ureditve

Identification of Risk Factors for Breast Cancer for Women in Istanbul

Background: Breast cancer is the most common cancer type seen in women, accounts for 18% of all cancer types in women and the risk of a woman to get breast cancer during her life is 11%. These notified rates enable breast cancer to be defined as a preventable and if pre-diagnosed, a treatable cancer type, despite it was regarded as a terrifying type of cancer in the past. Objective: The aim of the study was to determine the lifestyle pattern of women without breast cancer in Istanbul. Method: The study was carried out as a descriptive and cross-sectional study with 1000 women. Results: The majority of the women (29.7%) were in the 35-44 year old age group. Out of these 93.1% gave birth before the age of 30, 29.5% breastfed for 7-12 months, 65.8% started menarche between 13-15 years of age (mean of 13.3 years), 15.5% were in menopause and had entered menopause at a mean age of 46.5 years. Their mean body mass index was 24.3kg/m2 and 24.5% of them preferred foods containing high fat content. The majority of the women (85.4%) did not participate in sports regularly. One third (30.3%) of the women had underwent Breast Self Examination. There was a positive family history of breast cancer for 12.1% of the women. Conclusion: Sedentary lifestyles, lower Breast Self Examination and routine mammography rates and family histories of breast cancer were the risk factors that needed to be given priority for further action

Uncovering the Relation between CK and PCK: An Investigation of Preservice Elementary Mathematics Teachers’ Algebra Teaching Knowledge

This article discuss the algebra teaching knowledge of preservice elementary mathematics teachers in the context of CK and PCK as well as the relationship between them. The study was conducted with 101 preservice teachers sampled from a state university in Turkey. Rasch analysis was used to interpret the data. The results revealed that preservice teachers performed at mid-level for both CK and PCK tests. It was also found that there was significant correlation between the CK and PCK test scores. Weaknesses of the preservice teachers in terms of knowledge of the learner component of PCK, in comparison with presentation of content, were identified

The effect of different puzzolanic additives on mechanical properties of cement mortars

Bu çalışmada, Soma termik santralinden elde edilen uçucu kül, iki farklı tras (Yenişehir, Bilecik) ve silis dumanı, çimento klinkerinin bir kısmı yerine katılmış ve elde edilen harçların basınç dayanım değerleri incelenmiştir. Ağırlıkça %5 silis dumanı içeren çimentoya %10 uçucu kül katılmıştır ve tras oranları ise %30, %35 ve %40 olarak değiştirilmiştir. Bu karışımların her birinin kimyasal analizleri yapılarak Blaine özgül yüzey alanı değerleri ölçülmüştür. Bu bulgular ışığında basınç dayanım sonuçları irdelenmiştir. Yapılan denemelerde en yüksek dayanım değerlerinin Bilecik trası ile hazırlanan ve yüksek inceliğe sahip olan puzolan içeren harçlarda elde edildiği saptanmıştır.In this study, cement mortar samples containing fly ash obtained from Soma Power Plant, two different types of natural pozzolan supplied from Yenişehir and Bilecik and silica fume from Antalya Ferrocrom Industry partial replacement of cement clinker. The strength of the mortars prepared by these mixtures were investigated. The mixtures were prepared by using 10% fly ash and 5% silica fume and the trass contents varied as 30%, 35%, and 40%. Chemical analyses of these mixtures were carried out and Blaine specific surface area values were measured. In performed tests, the highest strength values were noticed in mortars containing natural puzzolan from Bilecik which has high fineness

Usporedba metoda za procjenu dentalne i skeletne dobi djece

Objectives: Estimating age is a crucial determinant of forensic science. Various methods have been used to estimate dental age (DA) and skeletal age (SA).The aim of the current study was to compare the Cameriere’s DA method with the Cameriere’s SA method in estimating CA in children. Materials and methods: A total of 216 radiographs of 130 females and 86 males (between 9 to 14.99 years of age) were evaluated in northwestern Turkey. DA was calculated on the panoramic images using Cameriere’s open apex method. SA was determined on the lateral cephalograms using the fourth cervical vertebrae method by Cameriere. The DA, SA, and CA data were compared using a paired t-test and Wilcoxon test. Results: The mean CA of all groups was calculated as 12.96±0.30, the mean DA of 12.74±0.68 and the mean SA of 12.89±0.89. In males, the DA method presented an underestimation between ages of 14.00 and 14.99 (p<0.05) and an overestimation between ages 9.00 and 11.99 (p<0.05). In females, the DA method showed an underestimation in the 13.00- and 14.99-year-old age groups (p<0.05) and an overestimation in the 10.00- and 11.99-year-old age groups (p<0.05). The SA method revealed a significant underestimation in females between the ages of 13.00 and 14.99 and in males between the ages of 14.00 and 14.99 (p<0.05). Conclusions: The SA estimation method may provide more accurate results compared to the DA method with children of both sexes aged between 9.00 to 12.99 in the determination of CA.Svrha istraživanja: Procjena dobi ključna je odrednica forenzičke znanosti. Za procjenu dentalne dobi (DA) i skeletne dobi (SA) korištene su različite metode. Cilj ovog istraživanja bio je usporediti Cameriereovu DA metodu s Cameriereovom SA metodom u procjeni kronološke dobi (CA) djece. Materijal i metode: Ukupno 216 rendgenskih snimki 130 djevojčica i 86 dječaka (u dobi između 9 i 14,99 go-dina) procijenjeno je u sjeverozapadnoj Turskoj. DA je izračunat na ortopantomogramima s pomoću Cameriereove metode otvorenog apeksa. SA je određen na lateralnim kefalogramima metodom četvrtoga vratnog kralješka prema Cameriereu. DA, SA i CA podatci uspoređeni su s pomoću uparenoga t-testa i Wilcoxonova testa. Rezultati: Srednji CA svih skupina iznosio je 12,96 ± 0,30, srednji DA bio je 12,74 ± 0,68, a srednji SA 12,89 ± 0,89. Kod dječaka je DA metoda rezultirala podcjenjivanjem dobi između 14,00 i 14,99 godina (p < 0,05) i precjenjivanjem između 9,00 i 11,99 godina (p < 0,05). Kod djevojčica je DA metoda pokazala podcjenjivanje u dobnim skupinama od 13,00 do 14,99 godina (p < 0,05) i precjenjivanje u dobnim skupinama od 10,00 do 11,99 godina (p < 0,05). SA metodom utvrđeno je značajno podcjenjivanje kod djevojčica u dobi od 13,00 do 14,99 godina i kod dječaka između 14,00 i 14,99 godina (p < 0,05). Zaključak: Metoda procjene SA-e može dati točnije rezultate u usporedbi s metodom DA-e kod djece obaju spolova u dobi od 9,00 do 12,99 godina u određivanju CA-e

Supporting novice mathematics teachers: The impact of an e- mentoring and video-based professional development program on teachers? noticing skills

Karadeniz Technical University Scientific Research Foundation [7178]The study was supported by Karadeniz Technical University Scientific Research Foundation with the project number 7178.This paper focuses on e-mentoring of novice mathematics teachers as professional development, and reports findings of the e-mentoring practices enriched with videos to improve noticing skills of novice teachers. A single group pre- and post-test study was conducted with the participation of 17 mentees, novice middle school mathematics teachers. Participants' noticing skills were assessed through a whole-class teaching video shown to them before and after the intervention. The responses of the teachers to the video assessment were analyzed considering attending, interpreting and decision-making dimensions of noticing. The results revealed that the ementoring program improved the novice mathematics teachers' noticing skills significantly in all dimensions.WOS:000978797700007Emerging Sources Citation IndexarticleUluslararası işbirliği ile yapılmayan - HAYIRMayıs2023YÖK - 2022-2

Endometrium Kanserli Hastalarda Preoperatif Tam Kan Sayımının Prognostik Parametreler ve Sağkalımla İlişkisi

Amaç: Çalışmamızda endometriyum adenokarsinomu tanılı hastalarda preoperatif tam kan sayımı parametrelerinin çeşitli klinikopatolojik prognostik parametrelerle ve sağkalım ile ilişkisi olup olmadığını değerlendirmeyi amaçladık.Gereç ve Yöntem: Ocak 2011-Aralık 2014 tarihleri arasında fakültemizde opere edilen ve endometrial adenokarsinom tanısı alan 144 hasta çalışmaya dahil edilmiştir. Hemogram parametrelerinden absolü beyaz küre sayısı BK , absolü platelet sayısı Plt hematokrit Hct , hemoglobin Hb değerleri yanı sıra absolü nötrofil sayısının absolü lenfosit sayısına bölümü olan NLR, absolü platelet sayısının absolü lenfosit sayısına bölümü olan PLR ve absolü monosit sayısının absolü lenfosit sayısına bölümü olan MLR oranlarının; tümör çapı, tümör derecesi, FIGO evresi, serviks invazyonu, pozitif lenf nodu sayısı, lenf nodunda ekstrakapsüler yayılım, lenfovasküler invazyon LVİ , myometrial invazyon derinliği gibi prognostik parametreler ve hastalıksız ve genel sağkalım süreleri ile olan ilişkisi istatistiksel metodlarla araştırılmıştır.Bulgular: Derece 3 tümöre sahip hastalarda BK sayısının derece 1 tümörlü hastalara göre anlamlı derecede düşük olduğu görüldü p=0.04 . LVİ olan olgularda PLR p=0.018 ve MLR p=0.028 LVİ olmayan hastalara göre daha düşük idi. Düşük evre olgularda evre I-II PLR, yüksek evreli olgulara göre evre II-III daha düşük tespit edildi p=0.03 . Tedavi öncesi bakılan tam kan parametreleri ile tümör çapı, serviks invazyonu, pozitif lenf nodu sayısı, lenf nodunda ekstrakapsüler yayılım, myometrial invazyon derinliği, hastalıksız sağkalım ve genel sağkalım arasında anlamlı bir ilişki saptanmadı p>0.05 .Sonuç: Endometriyum kanserinde tedavi öncesi tam kan sayımı parametrelerinin bir arada kullanılması, hastalığın prognozu ile ilgili fikir verebilir. Çalışmamızın sonuçlarının daha uzun takip süresine ve daha geniş olgu sayısına sahip çalışmalarla desteklenmesi gereklidi

Nuclear Factor Erythroid 2-Related Factor (NRF2), Heme Oxygenase 1 (HO-1) and Total Oxidant-Antioxidant Status in Patients with COVID-19

Introduction: Studies on nuclear factor erythroid 2-related factor 2 (Nrf2) and heme oxygenase-1 (HO-1) levels in COVID-19 patients are limited. This study aimed to investigate the relationship between some biomarkers of oxidant-antioxidant status with COVID-19 disease. Material and methods: The patients older than 18 years of age who tested positive for SARS CoV-2 PCR (polymerase chain reaction) with clinical symptoms and signs were included in this study. Total antioxidant status (TAS), total antioxidant status (TOS), oxidative stress index (OSI) and HO-1 and Nrf2 levels were analyzed from serum samples taken before and after treatment. Results: In this study, 16 patients followed up with the diagnosis of COVID-19 were included. 9 (56.3%) of the patients were female and 7 (43.8%) were male. The mean age was 33.75 ± 17.03 years. All patients were symptomatic and were hospitalized to be followed up. It was determined that Nrf2 and HO-1 values increased significantly after treatment. Moreover, there was a significant positive correlation between Nrf2 and TAS values and TAS increases significantly in parallel to an increase in Nrf2, and there was a significant but negative correlation between Nrf2 and TOS and OSI values, and thus an increase in Nrf2 led to a decrease in TOS and OSI values. There was a significant positive correlation between HO-1 and TAS, and TAS increased significantly, as HO-1 increased. Conclusions: The decrease in TOS and OSI and the increase in Nrf2 and HO-1 during the follow-up period in COVID-19 patients suggest that the body tries to prevent ROS-related oxidative stress via Nrf2 and HO-1 and that oxidative stress may have a key role in the pathophysiology of COVID-19

Role of pyroptosis in COVID-19

Aim: In this study, we aimed to investigate the relationship between gasdermin-D, caspase-1, IL-1β and NLRP3, biomarkers that play an important role in COVID-19, and pyroptosis. Material and Methods: This study was carried out with 58 participants, 28 (48.28%) of whom were diagnosis with COVID-19, and 30 (51.72%) of whom were healthy volunteers (control group). Results: There were no statistically significant differences between the gasdermin-D, caspase-1, IL-1β, and NLRP3 levels as a result of all statistical comparisons performed. However, IL-1β values both during the discharge period and during the hospitalization period were considerably higher than those of the control group. At the discharge period, IL-1β values of the patients with severe COVID-19 category had higher than moderate patients, and the patients with moderate than the patients with mild patients. Conclusion: It was observed that IL-1β, which is one of the cytokines released as a result of cell death in the pyroptosis mechanism, was higher in the COVID-19 patients in both the hospitalization and discharge periods compared to the control group. Although not statistically significant these results could support the relationship between pyroptosis and COVID-19