Survival following vertebral compression fractures in population over 65 years old

Lower mortality has been demonstrated when vertebral compression fractures (VCFs) are treated surgically (vertebral augmentation) vs. conservatively. To analyze the overall survival in patients over 65 who sufer a VCF, to review the principal causes of death, and to detect which factors are associated with a greater risk of mortality. Patients over 65 years old diagnosed with acute, non-pathologic thoracic or lumbar VCF, treated consecutively from January 2017 to December 2020, were retrospectively selected. Those patients with follow-ups under 2 years or who required arthrodesis were excluded. Overall survival was estimated by the Kaplan–Meier method. Diferences in survival were tested through the log-rank test. Multivariable Cox regression was used to assess the association of covariates and time to death. A total of 492 cases were included. Overall mortality was 36.2%. Survival rate at 1-, 12-, 24-, 48-, and 60-month follow-up was 97.4%, 86.6%, 78.0%, 64.4%, and 59.4%, respectively. Infection was the leading cause of death. The independent factors associated with a higher mortality risk were age, male, oncologic history, non-traumatic mechanism, and comorbidity during hospitalization. No statistical diference was found when comparing the two survival curves by treatment (vertebral augmentation vs. conservative) over time. Overall mortality rate was 36.2% after a median follow-up of 50.5 months (95% CI 48.2; 54.2). Age, male sex, history of oncological disease, non-traumatic mechanism of the fracture, and any comorbidity during hospitalization were identifed as variables independently associated with a higher risk of mortality following a VCF in the elderl

XXXIII Congreso Nacional de riegos Valencia 16 - 18 junio de 2015

Esta es la trigésimo tercera edición del Congreso Nacional de Riegos, que reúne a investigadores y técnicos de toda España que desarrollan su actividad en temas del riego regadíos. El congreso está dividido en cuatro secciones, que de forma resumida cubren los siguientes aspectos: A) Agrohidrología. Hidrología del riego. B) Salinidad, Drenaje, Efectos Ambientales y Agua de riego C) Ingeniería y Modernización del Riego D) Gestión, Legislación, Economía del Riego y Otros El congreso tiene fuerte arraigo entre las empresas del sector, que montan stands para dar difusión a sus novedades mientras se está desarrollando el congreso. Se habilita una sesión específica para que presenten sus innovaciones técnicas.Arviza Valverde, J.; Royuela Tomás, Á. (2015). XXXIII Congreso Nacional de riegos Valencia 16 - 18 junio de 2015. Editorial Universitat Politècnica de València. http://hdl.handle.net/10251/51610Archivo delegad

MÉTODO ALTERNATIVO DE ESTIMACIÓN DEL COEFICIENTE DE VARIACIÓN DE UN EMISOR DE RIEGO LOCALIZADO

[ES] El Coeficiente de Variación de fabricación de un emisor CV se determina según la Norma UNE-EN-ISO-9261 a partir de un único ensayo de laboratorio. Este procedimiento puede conllevar la no correcta determinación del CV, ya que en el ensayo los errores de medida atribuibles a los equipos o al proceso de medición pueden provocar la aparición de datos anómalos difíciles de detectar, además de que el CV así obtenido sólo sería válido para la presión de ensayo. En el presente trabajo se utilizan los resultados de los ensayos de 5 emisores no autocompensantes y 5 autocompensantes sometidos a diferentes presiones dentro del rango de trabajo de los mismos, y con ellos se determinan los caudales y los coeficientes de variación reales para cada presión y se ajustan unas funciones de predicción del caudal medio y del caudal emitido por cada emisor individual. A partir de estas funciones, se pueden calcular los caudales y los coeficientes de variación predichos para cada presión. Además, también se proponen unas funciones de ajuste para predecir la evolución del CV con la presión, tanto para los valores de caudal reales como para los predichos. Las principales conclusiones son que el CV en general depende de la presión para cualquier tipo de emisores y que el modelo propuesto de predicción de los caudales y del CV es correcto y consigue reducir el efecto de los posibles datos de caudal anómalos que aparecen en los ensayos.Turégano Pastor, JV.; Martí Pérez, P.; Royuela Tomás, Á. (2015). MÉTODO ALTERNATIVO DE ESTIMACIÓN DEL COEFICIENTE DE VARIACIÓN DE UN EMISOR DE RIEGO LOCALIZADO. En XXXIII CONGRESO NACIONAL DE RIEGOS. Valencia 16-18 junio de 2015. Editorial Universitat Politècnica de València. https://doi.org/10.4995/CNRiegos.2015.1514OC

Uracil grafted imine-based covalent organic framework for nucleobase recognition

An imine-based covalent organic framework (COF) decorated in its cavities with uracil groups has shown selective recognition towards adenine in water. These results show how the confinement of the base-pair inside the COF's pores allows a remarkable selective recognition in aqueous mediaThis work was financially supported by MINECO (MAT2016-77608-C3-1-P and 2-P, SAF2017-87305-R). IMDEA Nanociencia acknowledges support from the ‘Severo Ochoa’ Programme for Centres of Excellence in R&D (MINECO, Grant SEV-2016-0686). Funding from the European Research Council (ERC-StG 279548) and MINECO (CTQ2014-27729-P and CTQ2017-84727-P) is gratefully acknowledged (DGR

Probabilistic combination of eigenlungs-based classifiers for COVID-19 diagnosis in chest CT images

The outbreak of the COVID-19 (Coronavirus disease 2019) pandemic has changed the world. According to the World Health Organization (WHO), there have been more than 100 million confirmed cases of COVID-19, including more than 2.4 million deaths. It is extremely important the early detection of the disease, and the use of medical imaging such as chest X-ray (CXR) and chest Computed Tomography (CCT) have proved to be an excellent solution. However, this process requires clinicians to do it within a manual and time-consuming task, which is not ideal when trying to speed up the diagnosis. In this work, we propose an ensemble classifier based on probabilistic Support Vector Machine (SVM) in order to identify pneumonia patterns while providing information about the reliability of the classification. Specifically, each CCT scan is divided into cubic patches and features contained in each one of them are extracted by applying kernel PCA. The use of base classifiers within an ensemble allows our system to identify the pneumonia patterns regardless of their size or location. Decisions of each individual patch are then combined into a global one according to the reliability of each individual classification: the lower the uncertainty, the higher the contribution. Performance is evaluated in a real scenario, yielding an accuracy of 97.86%. The large performance obtained and the simplicity of the system (use of deep learning in CCT images would result in a huge computational cost) evidence the applicability of our proposal in a real-world environment.Comment: 15 pages, 9 figure

PROYECTO FIGARO: PLATAFORMA PARA LA GESTIÓN INTEGRAL Y EFICIENTE DEL RIEGO

[EN] Water and energy consumptions at plot level irrigation are issues of broad interest with an important environmental and economic impact. The solution to this double challenge requires the implementation of “precise irrigation”. In this work is shown the under developing software system FIGARO (Flexible and PrecIse IrriGation PlAtform to Improve FaRm Scale Water PrOductivity), which is part of a project co-funded by the European Commission under the 7th Framework Programme, in the scope of “Precision technologies to improve irrigation management and increase water productivity in major water-demanding crops in Europe” (KBBE.2012.1.1-03). The aim is to develop a tool to support decision-making for end users that let them perform irrigation scheduling with the aim of reducing water, energy and fertilizers consumptions, as well as yield crop is maximized. Implementation and validation of the FIGARO platform is being performed in several countries with different crops and weather conditions. First results in the year 2014, in citrus and grapevine crops, suggest increases in water productivity with savings close to 30% of water and 36% of energy at Water User Association level.[ES] El consumo de agua y energía en el ámbito del riego en parcela es una cuestión de amplio interés y consecuencias para el medio ambiente y la economía. La solución a este doble reto exige la implantación del denominado “riego de precisión”. En el presente trabajo se presenta la plataforma informática en desarrollo FIGARO (Flexible and PrecIse IrriGation PlAtform to Improve FaRm Scale Water PrOductivity), la cual forma parte de un proyecto financiado por la Unión Europea dentro del 7º Programa Marco, en el ámbito “Precision technologies to improve irrigation management and increase water productivity in major water-demanding crops in Europe” (KBBE.2012.1.1-03). El objetivo principal es desarrollar una herramienta de soporte a la toma de decisiones, que permita a los agricultores realizar programaciones de riego dirigidas a reducir el uso de agua, energía y fertilizantes, a la vez que se maximiza la productividad de las cosechas. La puesta en marcha y validación de la plataforma FIGARO se está llevado a cabo en diferentes países, con cultivos y condiciones climáticas diversas. Los primeros resultados de la campaña de 2014 en cultivos de cítrico y vid, sugieren incrementos de la productividad del agua con ahorros próximos al 30% de agua y del 36% de energía a nivel de comunidad de regantes.Este trabajo ha sido financiado por Unión Europea dentro del 7º Programa Marco, en el ámbito “Precision technologies to improve irrigation management and increase water productivity in major water-demanding crops in Europe” (KBBE.2012.1.1-03).Martínez Gimeno, M.; Martínez Alzamora, F.; Jiménez Bello, MÁ.; Royuela Tomás, Á.; Manzano Juarez, J.; Intrigliolo Molina, DS. (2015). PROYECTO FIGARO: PLATAFORMA PARA LA GESTIÓN INTEGRAL Y EFICIENTE DEL RIEGO. En XXXIII CONGRESO NACIONAL DE RIEGOS. Valencia 16-18 junio de 2015. Editorial Universitat Politècnica de València. https://doi.org/10.4995/CNRiegos.2015.1457OC

Lung transplantation from uncontrolled and controlled donation after circulatory death: similar outcomes to brain death donors

Controlled donation after circulatory death donors (cDCD) are becoming a frequent source of lungs grafts worldwide. Conversely, lung transplantations (LTx) from uncontrolled donors (uDCD) are sporadically reported. We aimed to review our institutional experience using both uDCD and cDCD and compare to LTx from brain death donors (DBD). This is a retrospective analysis of all LTx performed between January 2013 and December 2019 in our institution. Donor and recipient characteristics were collected and univariate, multivariate and survival analyses were carried out comparing the three cohorts of donors. A total of 239 (84.7%) LTx were performed from DBD, 29 (10.3%) from cDCD and 14 (5%) from uDCD. There were no statistically significant differences in primary graft dysfunction grade 3 at 72 h, 30- and 90-day mortality, need for extracorporeal membrane oxygenation after procedure, ICU and hospital length of stay, airway complications, CLAD incidence or survival at 1 and 3 years after transplant (DBD: 87.1% and 78.1%; cDCD: 89.7% and 89.7%; uDCD: 85.7% and 85.7% respectively; P = 0.42). Short- and mid-term outcomes are comparable between the three types of donors. These findings may encourage and reinforce all types of donation after circulatory death programmes as a valid and growing source of suitable organs for transplantatio

1st BSC Doctoral Symposium : book of abstracts

Peer Reviewe

Riesgo quirúrgico tras resección pulmonar anatómica en cirugía torácica. Modelo predictivo a partir de una base de datos nacional multicéntrica

Introduction: the aim of this study was to develop a surgical risk prediction model in patients undergoing anatomic lung resections from the registry of the Spanish Video-Assisted Thoracic Surgery Group (GEVATS). Methods: data were collected from 3,533 patients undergoing anatomic lung resection for any diagnosis between December 20, 2016 and March 20, 2018. We defined a combined outcome variable: death or Clavien Dindo grade IV complication at 90 days after surgery. Univariate and multivariate analyses were performed by logistic regression. Internal validation of the model was performed using resampling techniques. Results: the incidence of the outcome variable was 4.29% (95% CI 3.6-4.9). The variables remaining in the final logistic model were: age, sex, previous lung cancer resection, dyspnea (mMRC), right pneumonectomy, and ppo DLCO. The performance parameters of the model adjusted by resampling were: C-statistic 0.712 (95% CI 0.648-0.750), Brier score 0.042 and bootstrap shrinkage 0.854. Conclusions: the risk prediction model obtained from the GEVATS database is a simple, valid, and reliable model that is a useful tool for establishing the risk of a patient undergoing anatomic lung resection

Psychometric characteristics of the Spanish version of instruments to measure neck pain disability

[EN] Background. The NDI, COM and NPQ are evaluation instruments for disability due to NP. There was no Spanish version of NDI or COM for which psychometric characteristics were known. The objectives of this study were to translate and culturally adapt the Spanish version of the Neck Disability Index Questionnaire (NDI), and the Core Outcome Measure (COM), to validate its use in Spanish speaking patients with non-specific neck pain (NP), and to compare their psychometric characteristics with those of the Spanish version of the Northwick Pain Questionnaire (NPQ). Methods. Translation/re-translation of the English versions of the NDI and the COM was done blindly and independently by a multidisciplinary team. The study was done in 9 primary care Centers and 12 specialty services from 9 regions in Spain, with 221 acute, subacute and chronic patients who visited their physician for NP: 54 in the pilot phase and 167 in the validation phase. Neck pain (VAS), referred pain (VAS), disability (NDI, COM and NPQ), catastrophizing (CSQ) and quality of life (SF-12) were measured on their first visit and 14 days later. Patients' self-assessment was used as the external criterion for pain and disability. In the pilot phase, patients' understanding of each item in the NDI and COM was assessed, and on day 1 test-retest reliability was estimated by giving a second NDI and COM in which the name of the questionnaires and the order of the items had been changed. Results. Comprehensibility of NDI and COM were good. Minutes needed to fill out the questionnaires [median, (P25, P75)]: NDI. 4 (2.2, 10.0), COM: 2.1 (1.0, 4.9). Reliability: [ICC, (95%CI)]: NDI: 0.88 (0.80, 0.93). COM: 0.85 (0.75,0.91). Sensitivity to change: Effect size for patients having worsened, not changed and improved between days 1 and 15, according to the external criterion for disability: NDI: -0.24, 0.15, 0.66; NPQ: -0.14, 0.06, 0.67; COM: 0.05, 0.19, 0.92. Validity: Results of NDI, NPQ and COM were consistent with the external criterion for disability, whereas only those from NDI were consistent with the one for pain. Correlations with VAS, CSQ and SF-12 were similar for NDI and NPQ (absolute values between 0.36 and 0.50 on day 1, between 0.38 and 0.70 on day 15), and slightly lower for COM (between 0.36 and 0.48 on day 1, and between 0.33 and 0.61 on day 15). Correlation between NDI and NPQ: r = 0.84 on day 1, r = 0.91 on day 15. Correlation between COM and NPQ: r = 0.63 on day 1, r = 0.71 on day 15. Conclusion. Although most psychometric characteristics of NDI, NPQ and COM are similar, those from the latter one are worse and its use may lead to patients' evolution seeming more positive than it actually is. NDI seems to be the best instrument for measuring NP-related disability, since its results are the most consistent with patient's assessment of their own clinical status and evolution. It takes two more minutes to answer the NDI than to answer the COM, but it can be reliably filled out by the patient without assistanceS