Catalog of Nearby Isolated Galaxies in the Volume z<0.01

We present a catalog of 520 most isolated nearby galaxies with radial velocities V_LG<3500 km/s covering the entire sky. This population of "space orphans" makes up 4.8% among 10900 galaxies with measured radial velocities. We describe the isolation criterion used to select our sample, called the "Local Orphan Galaxies" (LOG), and discuss their basic optical and HI properties. A half of the LOG catalog is occupied by the Sdm, Im and Ir morphological type galaxies without a bulge. The median ratio M_gas/M_star in the LOG galaxies exceeds 1. The distribution of the catalog galaxies on the sky looks uniform with some signatures of a weak clustering on the scale of about 0.5 Mpc. The LOG galaxies are located in the regions where the mean local density of matter is approximately 50 times lower than the mean global density. We indicate a number of LOG galaxies with distorted structures, which may be the consequence of interaction of isolated galaxies with massive dark objects

Dust and star formation properties of a complete sample of local galaxies drawn from the Planck Early Release Compact Source Catalogue

We combine Planck High Frequency Instrument data at 857, 545, 353 and 217 GHz with data from Wide-field Infrared Survey Explorer (WISE), Spitzer, IRAS and Herschel to investigate the properties of a well-defined, flux-limited sample of local star-forming galaxies. A 545 GHz flux density limit was chosen so that the sample is 80 per cent complete at this frequency, and the resulting sample contains a total of 234 local, star-forming galaxies. We investigate the dust emission and star formation properties of the sample via various models and calculate the local dust mass function. Although single-component-modified blackbodies fit the dust emission longward of 80 \u3bcm very well, with a median \u3b2 = 1.83, the known degeneracy between dust temperature and \u3b2 also means that the spectral energy distributions are very well described by a dust component with dust emissivity index fixed at \u3b2 = 2 and temperature in the range 10-25 K. Although a second, warmer dust component is required to fit shorter wavelength data, and contributes approximately a third of the total infrared emission, its mass is negligible. No evidence is found for a very cold (6-10 K) dust component. The temperature of the cold dust component is strongly influenced by the ratio of the star formation rate to the total dust mass. This implies, contrary to what is often assumed, that a significant fraction of even the emission from \u2dc20 K dust is powered by ongoing star formation, whether or not the dust itself is associated with star-forming clouds or `cirrus'. There is statistical evidence of a free-free contribution to the 217 GHz flux densities of 7220 per cent. We find a median dust-to-stellar mass ratio of 0.0046; and that this ratio is anticorrelated with galaxy mass. There is good correlation between dust mass and atomic gas mass (median Md/MHI = 0.022), suggesting that galaxies that have more dust (higher values of Md/M*) have more interstellar medium in general. Our derived dust mass function implies a mean dust mass density of the local Universe (for dust within galaxies), of 7.0 \ub1 1.4 7 105 M 99 Mpc-3, significantly greater than that found in the most recent estimate using Herschel data. \ua9 2013 The Authors Published by Oxford University Press on behalf of the Royal Astronomical Society

Cognitive therapy for depressed adults with comorbid social phobia

Item does not contain fulltextBackground: Evidence Suggests that comorbid depression influences the outcome of cognitive behavioral treatment for patients presenting with social phobia. Little is known, however, about the influence of comorbid social phobia on the response to cognitive therapy (CT) for depression among adults presenting with recurrent major depressive disorder (MDD). These analyses seek to clarify this relationship. Methods: Patients (N 156) with recurrent DSM-IV MDD entered CT (20% also met DSM-IV criteria for social phobia). Every week during the course of CT, clinicians assessed depressive symptoms and patients completed self-report instruments measuring severity of depression and anxiety. Results: At presentation, outpatients with comorbid social phobia reported greater levels of depressive symptoms and clinicians rated their impairment as more severe, compared to their counterparts without social phobia. Patients with or without comorbid social phobia did not differ significantly in (1) attrition rates; (2) response or sustained remission rates; (3) time to response or sustained remission; or (4) rate of improvement in symptoms of depression or anxiety. Limitations: The lack of domain-specific measures limits inference with respect to the improvements in social anxiety that occur with CT of depression. Conclusions: These findings introduce the hypothesis that CT for depression may be flexible enough to treat the depressive symptoms of patients presenting with MDD who also suffer from social phobia

Chemical Modification of a Nafion(R) Sulfonyl Fluoride Precursor Via In Situ Sol-Gel Reactions

The melt-processible sulfonyl fluoride precursor of a Nafion(R) ionomer was utilized as a sol-gel reaction medium for 3-aminopropyltriethoxysilane (APrTEOS). The diffusion-mediated reaction of APrTEOS with SO2F groups can be controlled with high degree of reaction. Fourier transform infra-red/attenuated total reflection studies show that sulfonamide linkages are formed and condensation reactions of SiOR groups provide covalent crosslinking of chains. Formic acid treatment plus high temperature plus long time resulted in a high degree of polymer crosslinking as seen in Si-29 solid state nuclear magnetic resonance spectra. Mechanical modulus and strength increase, and elongation-to-break decreases with increasing filler. Hybrids with \u3c18% uptake accumulate cracks with crosslinked outer layers, each event signalled by a drop in stress followed by stress recovery. While there are sharp visual material fronts inward from both surfaces, EDAX (energy dispersive analysis of X-rays) showed that there are no sharp Si composition boundaries. Differential scanning calorimetry (d.s.c.) revealed a broad, weak endothermic event peaking at 67 degrees C for the precursor and shifting to higher temperatures while broadening with increasing filler content, indicating progressively-restrictive glass-transition-temperature-related molecular motions within an increasingly nonhomogeneous environment. For the unreacted precursor, this d.s.c. transition occurs at a temperature just above a glass transition detected by dynamic mechanical means. (C) 1997 Elsevier Science Ltd

Melancholic and atypical depression as predictor and moderator of outcome in cognitive behavior therapy and pharmacotherapy for adult depression.

Background: Melancholic and atypical depression are widely thought to moderate or predict outcome of pharmacological and psychological treatments of adult depression, but that has not yet been established. This study uses the data from four earlier trials comparing cognitive behavior therapy (CBT) versus antidepressant medications (ADMs; and pill placebo when available) to examine the extent to which melancholic and atypical depression moderate or predict outcome in an “individual patient data” meta-analysis. Methods: We conducted a systematic search for studies directly comparing CBT versus ADM, contacted the researchers, integrated the resulting datasets from these studies into one big dataset, and selected the studies that included melancholic or atypical depressive subtyping according to DSM-IV criteria at baseline (n = 4, with 805 patients). After multiple imputation of missing data at posttest, mixed models were used to conduct the main analyses. Results: In none of the analyses was melancholic or atypical depression found to significantly moderate outcome (indicating a better or worse outcome of these patients in CBT compared to ADM; i.e., an interaction), predict outcome independent of treatment group (i.e., a main effect), or predict outcome within a given modality. The outcome differences between patients with melancholia or atypical depression versus those without were consistently very small (all effect sizes g < 0.10). Conclusions: We found no indication that melancholic or atypical depressions are significant or relevant moderators or predictors of outcome of CBT and ADM

Initial severity of depression and efficacy of cognitive-behaviour therapy: An individual-participant data meta-analysis of pill-placebo-controlled trials.

Background: The influence of baseline severity has been examined for antidepressant medications but has not been studied properly for cognitive-behavioural therapy (CBT) in comparison with pill placebo. Aims: To synthesise evidence regarding the influence of initial severity on efficacy of CBT from all randomised controlled trials (RCTs) in which CBT, in face-to-face individual or group format, was compared with pill-placebo control in adults with major depression. Method: A systematic review and an individual-participant data meta-analysis using mixed models that included trial effects as random effects. We used multiple imputation to handle missing data. Results: We identified five RCTs, and we were given access to individual-level data (n= 509) for all five. The analyses revealed that the difference in changes in Hamilton Rating Scale for Depression between CBT and pill placebo was not influenced by baseline severity (interaction P=0.43). Removing the non-significant interaction term from the model, the difference between CBT and pill placebo was a standardised mean difference of 70.22 (95% CI 70.42 to 70.02, P =0.03, I2 = 0%). Conclusions: Patients suffering from major depression can expect as much benefit from CBT across the wide range of baseline severity. This finding can help inform individualised treatment decisions by patients and their clinicians

Psychotherapy or medication for depression? Using individual symptom meta-analyses to derive a Symptom-Oriented Therapy (SOrT) metric for a personalised psychiatry

Background: Antidepressant medication (ADM) and psychotherapy are effective treatments for major depressive disorder (MDD). It is unclear, however, if treatments differ in their effectiveness at the symptom level and whether symptom information can be utilised to inform treatment allocation. The present study synthesises comparative effectiveness information from randomised controlled trials (RCTs) of ADM versus psychotherapy for MDD at the symptom level and develops and tests the Symptom-Oriented Therapy (SOrT) metric for precision treatment allocation. Methods: First, we conducted systematic review and meta-analyses of RCTs comparing ADM and psychotherapy at the individual symptom level. We searched PubMed Medline, PsycINFO, and the Cochrane Central Register of Controlled Trials databases, a database specific for psychotherapy RCTs, and looked for unpublished RCTs. Random-effects meta-analyses were applied on sum-scores and for individual symptoms for the Hamilton Rating Scale for Depression (HAM-D) and Beck Depression Inventory (BDI) measures. Second, we computed the SOrT metric, which combines meta-analytic effect sizes with patients' symptom profiles. The SOrT metric was evaluated using data from the Munich Antidepressant Response Signature (MARS) study (n = 407) and the Emory Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) study (n = 234). Results: The systematic review identified 38 RCTs for qualitative inclusion, 27 and 19 for quantitative inclusion at the sum-score level, and 9 and 4 for quantitative inclusion on individual symptom level for the HAM-D and BDI, respectively. Neither meta-analytic strategy revealed significant differences in the effectiveness of ADM and psychotherapy across the two depression measures. The SOrT metric did not show meaningful associations with other clinical variables in the MARS sample, and there was no indication of utility of the metric for better treatment allocation from PReDICT data. Conclusions: This registered report showed no differences of ADM and psychotherapy for the treatment of MDD at sum-score and symptom levels. Symptom-based metrics such as the proposed SOrT metric do not inform allocation to these treatments, but predictive value of symptom information requires further testing for other treatment comparisons