Digital Tectonics as a Morphogenetic Process

p. 938-948Tectonics is a seminal concept that defines the nature of the relationship between architecture and its structural properties. The changing definition of the symbiotic relationship between structural engineering and architectural design may be considered one of the formative influences on the conceptual evolution of tectonics in different historical periods. Recent developments in the field of morphogenesis, digital media, theories techniques and methods of digital design have contributed a new models of integration between structure, material and form in digital tectonics. The objective of this paper is to propose and define tectonics as a model of morphogenetic process. The paper identifies and presents the manner in which theory and emerging concepts of morphogenesis as well as digital models of design are contributing to this new model. The paper first analyzes the historical evolution of tectonics as a concept and characterizes the emergence of theoretical framework reflected in concepts and terms related to morphogenesis.Oxman, R. (2010). Digital Tectonics as a Morphogenetic Process. Editorial Universitat Politècnica de València. http://hdl.handle.net/10251/695

The Kinetic Basis of Morphogenesis

It has been shown recently (Shalygo, 2014) that stationary and dynamic patterns can arise in the proposed one-component model of the analog (continuous state) kinetic automaton, or kinon for short, defined as a reflexive dynamical system with active transport. This paper presents extensions of the model, which increase further its complexity and tunability, and shows that the extended kinon model can produce spatio-temporal patterns pertaining not only to pattern formation but also to morphogenesis in real physical and biological systems. The possible applicability of the model to morphogenetic engineering and swarm robotics is also discussed.Comment: 8 pages. Submitted to the 13th European Conference on Artificial Life (ECAL-2015) on March 10, 2015. Accepted on April 28, 201

Labyrinthine Turing Pattern Formation in the Cerebral Cortex

I propose that the labyrinthine patterns of the cortices of mammalian brains may be formed by a Turing instability of interacting axonal guidance species acting together with the mechanical strain imposed by the interconnecting axons.Comment: See home page http://lec.ugr.es/~julya

Dynamic Image-Based Modelling of Kidney Branching Morphogenesis

Kidney branching morphogenesis has been studied extensively, but the mechanism that defines the branch points is still elusive. Here we obtained a 2D movie of kidney branching morphogenesis in culture to test different models of branching morphogenesis with physiological growth dynamics. We carried out image segmentation and calculated the displacement fields between the frames. The models were subsequently solved on the 2D domain, that was extracted from the movie. We find that Turing patterns are sensitive to the initial conditions when solved on the epithelial shapes. A previously proposed diffusion-dependent geometry effect allowed us to reproduce the growth fields reasonably well, both for an inhibitor of branching that was produced in the epithelium, and for an inducer of branching that was produced in the mesenchyme. The latter could be represented by Glial-derived neurotrophic factor (GDNF), which is expressed in the mesenchyme and induces outgrowth of ureteric branches. Considering that the Turing model represents the interaction between the GDNF and its receptor RET very well and that the model reproduces the relevant expression patterns in developing wildtype and mutant kidneys, it is well possible that a combination of the Turing mechanism and the geometry effect control branching morphogenesis

About the freedom of free forms

p. 907-913This paper deals with the arrival of freedom at the world of structures giving birth a new generation of forms: the free forms. Its purpose is to analyze, to discuss and to comment critically this singular fact as well as their implications on the designers' task. It is more a philosophical than a technical paper. For centuries man has imagined new forms for their structures but he has not been always able to analyze and to build them. Before the arrival of the electronic calculus, the representation and analysis of structural forms could be limited to those ones belonging to the Euclidean Geometry. The computers broke those limitations and they gave wide freedom to the designers to conceive a new generation of forms; these new forms were called "free forms". Nowadays any form imagined can be represented, it can be analyzed and it can be built. Nevertheless not any imagined form can become a structural free form. Perhaps it could be a beautiful sculptural form, but not necessarily a structural one. For being a structural form, the inescapable laws of the mechanics must be satisfied. Moreover a structural free form can become an architectural free form just only when aesthetical, functional, environmental and social requirements, among others, are accomplished. Freedom has widened the horizons of creativity for the designers' task. Simultaneously new responsibilities have come altogether with this freedom. Today free form designers face permanent challenges; designers must be familiar with the menus of new and multiple tools created by the modern technology and they must be trained to make the right use of them. They must handle those wide menus in order to select the most appropriated options to generate, to model and to analyze the new free forms. At the same time they must select the most appropriated new materials and techniques to build these free forms. Finally, designer must be fully conscious of the high impact of their engineering and architectural works on the people and physical environment without forgetting their commitment to the society.Andres, OA. (2010). About the freedom of free forms. Editorial Universitat Politècnica de València. http://hdl.handle.net/10251/695

Topological Theory in Bioconstructivism

In the essay “Landscapes of Change: Boccioni’s Stati d’animo as a General Theory of Models,” in Assemblage 19, 1992, Sanford Kwinter proposed a number of theoretical models which could be applied to computer-generated forms in Bioconstructivism. These included topological theory, epigenesis, the epigenetic landscape, morphogenesis, catastrophe and catastrophe theory. Topological theory entails transformational events or deformations in nature which introduce discontinuities into the evolution of a system. Epigenesis entails the generation of smooth landscapes, in waves or the surface of the earth, for example, formed by complex underlying topological interactions. The epigenetic landscape is the smooth forms of relief which are the products of the underlying complex networks of interactions. Morphogenesis describes the structural changes occurring during the development of an organism, wherein forms are seen as discontinuities in a system, as moments of structural instability rather than stability. A catastrophe is a morphogenesis, a jump in a system resulting in a discontinuity. Catastrophe theory is a topological theory describing the discontinuities in the evolution of a system in nature. A project which applies these models, and which helps to establish a theoretical basis for Bioconstructivism by applying topological models, is a design for a theater by Amy Lewis in a Graduate Architecture Design Studio directed by Associate Professor Andrew Thurlow at Roger Williams University, in Spring 2011. In the project, moments of structural stability are juxtaposed with moments of structural instability, to represent the contradiction inherent in self-generation or immanence. The singularity of the surfaces of the forms in the epigenetic landscape contradicts the complex network of interactions of topological forces from which they result. Actions in the environment on unstable, unstructured forms, and undifferentiated structures, result in stable, structured forms, and differentiated structures

The last common bilaterian ancestor

Many regulatory genes appear to be utilized in at least superficially similar ways in the development of particular body parts in Drosophila and in chordates. These similarities have been widely interpreted as functional homologies, producing the conventional view of the last common protostome-deuterostome ancestor (PDA) as a complex organism that possessed some of the same body parts as modern bilaterians. Here we discuss an alternative view, in which the last common PDA had a less complex body plan than is frequently conceived. This reconstruction alters expectations for Neoproterozoic fossil remains that could illustrate the pathways of bilaterian evolution

Achilles And The Tortoise: Some Caveats To Mathematical Modeling In Biology

Mathematical modeling has recently become a much-lauded enterprise, and many funding agencies seek to prioritize this endeavor. However, there are certain dangers associated with mathematical modeling, and knowledge of these pitfalls should also be part of a biologist\u27s training in this set of techniques. (1) Mathematical models are limited by known science; (2) Mathematical models can tell what can happen, but not what did happen; (3) A model does not have to conform to reality, even if it is logically consistent; (4) Models abstract from reality, and sometimes what they eliminate is critically important; (5) Mathematics can present a Platonic ideal to which biologically organized matter strives, rather than a trial-and-error bumbling through evolutionary processes. This “Unity of Science” approach, which sees biology as the lowest physical science and mathematics as the highest science, is part of a Western belief system, often called the Great Chain of Being (or Scala Natura), that sees knowledge emerge as one passes from biology to chemistry to physics to mathematics, in an ascending progression of reason being purification from matter. This is also an informal model for the emergence of new life. There are now other informal models for integrating development and evolution, but each has its limitations