Results of the implementation of a virtual microscope in a course of histology

[EN] The course of Anatomy and Histology is studied in the first year of Dentistry at the University Cardenal Herrera CEU (Alfara del Patriarca, Spain). Its practices consist on choose freely six different tissue samples and draw their most representative features. These practices were made by optical microscopy until 2014, and in 2015 was introduced the virtual microscope exclusively. The aim of the study is to test whether this new teaching method has improved the quality of exercise and the understanding shown by students. First, the best exercises of both years were chosen, and from them some drawings from the same tissue were compared. Some tissues which samples for optical microscope were hard to obtain, were drawn for the very first time thanks to the virtual microscope. Also, with the virtual microscopy the drawings contained more details and definition. The understanding of the structures improved, shown by a more functional, detailed and defined vision of the tissues. The labels of the virtual microscope helped to the self-study and avoided the loss of unnoticed structures. In conclusion, replacement of optical microscope by the virtual microscope is a teaching improvement and facilitates student learning.Alegre-Martínez, A.; Martínez-Martínez, MI.; Alfonso Sanchez, JL.; Morales Suárez-Varela, MM.; Llopis Gonzalez, A. (2016). Results of the implementation of a virtual microscope in a course of histology. En 2nd. International conference on higher education advances (HEAD'16). Editorial Universitat Politècnica de València. 169-176. https://doi.org/10.4995/HEAD16.2015.2626OCS16917

Leveraging wall-sized high-resolution displays for comparative genomics analyses of copy number variation

The scale of comparative genomics data frequently overwhelms current data visualization methods on conventional (desktop) displays. This paper describes two types of solution that take advantage of wall-sized high-resolution displays (WHirDs), which have orders of magnitude more display real estate (i.e., pixels) than desktop displays. The first allows users to view detailed graphics of copy number variation (CNV) that were output by existing software. A WHirD's resolution allowed a 10× increase in the granularity of bioinformatics output that was feasible for users to visually analyze, and this revealed a pattern that had previously been smoothed out from the underlying data. The second involved interactive visualization software that was innovative because it uses a music score metaphor to lay out CNV data, overcomes a perceptual distortion caused by amplification/deletion thresholds, uses filtering to reduce graphical data overload, and is the first comparative genomics visualization software that is designed to leverage a WHirD's real estate. In a field evaluation, a clinical user discovered a fundamental error in the way their data had been processed, and established confidence in the software by using it to 'find' known genetic patterns in hepatitis C-driven hepatocellular cancer