BASS: boundary-aware superpixel segmentation

© 20xx IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.We propose a new superpixel algorithm based on exploiting the boundary information of an image, as objects in images can generally be described by their boundaries. Our proposed approach initially estimates the boundaries and uses them to place superpixel seeds in the areas in which they are more dense. Afterwards, we minimize an energy function in order to expand the seeds into full superpixels. In addition to standard terms such as color consistency and compactness, we propose using the geodesic distance which concentrates small superpixels in regions of the image with more information, while letting larger superpixels cover more homogeneous regions. By both improving the initialization using the boundaries and coherency of the superpixels with geodesic distances, we are able to maintain the coherency of the image structure with fewer superpixels than other approaches. We show the resulting algorithm to yield smaller Variation of Information metrics in seven different datasets while maintaining Undersegmentation Error values similar to the state-of-the-art methods.Peer ReviewedPostprint (author's final draft

Fast and accurate tumor segmentation of histology images using persistent homology and deep convolutional features

Tumor segmentation in whole-slide images of histology slides is an important step towards computer-assisted diagnosis. In this work, we propose a tumor segmentation framework based on the novel concept of persistent homology profiles (PHPs). For a given image patch, the homology profiles are derived by efficient computation of persistent homology, which is an algebraic tool from homology theory. We propose an efficient way of computing topological persistence of an image, alternative to simplicial homology. The PHPs are devised to distinguish tumor regions from their normal counterparts by modeling the atypical characteristics of tumor nuclei. We propose two variants of our method for tumor segmentation: one that targets speed without compromising accuracy and the other that targets higher accuracy. The fast version is based on the selection of exemplar image patches from a convolution neural network (CNN) and patch classification by quantifying the divergence between the PHPs of exemplars and the input image patch. Detailed comparative evaluation shows that the proposed algorithm is significantly faster than competing algorithms while achieving comparable results. The accurate version combines the PHPs and high-level CNN features and employs a multi-stage ensemble strategy for image patch labeling. Experimental results demonstrate that the combination of PHPs and CNN features outperforms competing algorithms. This study is performed on two independently collected colorectal datasets containing adenoma, adenocarcinoma, signet and healthy cases. Collectively, the accurate tumor segmentation produces the highest average patch-level F1-score, as compared with competing algorithms, on malignant and healthy cases from both the datasets. Overall the proposed framework highlights the utility of persistent homology for histopathology image analysis

Prototipo CAD de segmentación automática de cáncer de pulmón en imágenes histopatológicas TMA

El cáncer de pulmón es una enfermedad letal que para el 2012 se situó como la quinta causa de muerte a nivel mundial, la tercera en Europa y la primera en España con casi 20.000 nuevos casos cada año; aproximadamente el 85 % de los sujetos que padecen cáncer de pulmón, morirán por esta enfermedad. El principal obstáculo en la lucha contra esta patología es su detección tardía. El desarrollo que ha experimentado el campo de la imagen médica en aspectos como la adquisición, almacenamiento y visualización ha contribuido al mejoramiento de la calidad del análisis y diagnóstico de las diferentes patologías (entre ellas el cáncer de pulmón) convirtiéndola actualmente en un componente indispensable en medicina. En las últimas décadas, se han realizado numerosos esfuerzos para detectar de manera precoz el cáncer de pulmón mediante el desarrollo de distintas tecnologías, entre ellas los sistemas de diagnóstico asistido por computador (CAD), los cuales mediante el análisis automático de la imagen médica brindan al especialista una segunda opinión diagnostica, con el objetivo de obtener diagnósticos mas precisos que permitan formular tratamientos mas adecuados. La imagen médica histopatológica es el "gold standard. en detección temprana de la mayoría de patológicas incluido el cáncer de pulmón. La tarea de detección suele ser bastante tediosa e que implica una importante inversión de tiempo y esfuerzo por parte de los expertos en histopatología. El crecimiento de los bancos de tejidos ya ha superado las habilidades manuales de análisis disponibles. Además, la revisión de patología experta sufre variaciones ínter e intra observador. Lo anterior evidencia la gran necesidad de automatizar el análisis de imagen médica en histopatológica. En este trabajo se hace una aproximación a la detección de cáncer de pulmón en imagen médica, concretamente abordando el problema de segmentación de tejido tumoral y no tumoral sobre imágenes histopatológicas TMA, mediante el desarrollo de un prototipo de sistema de diagnóstico asistido por computador CAD

Texture and Colour in Image Analysis

Research in colour and texture has experienced major changes in the last few years. This book presents some recent advances in the field, specifically in the theory and applications of colour texture analysis. This volume also features benchmarks, comparative evaluations and reviews