Parameterized complexity of the MINCCA problem on graphs of bounded decomposability

In an edge-colored graph, the cost incurred at a vertex on a path when two incident edges with different colors are traversed is called reload or changeover cost. The "Minimum Changeover Cost Arborescence" (MINCCA) problem consists in finding an arborescence with a given root vertex such that the total changeover cost of the internal vertices is minimized. It has been recently proved by G\"oz\"upek et al. [TCS 2016] that the problem is FPT when parameterized by the treewidth and the maximum degree of the input graph. In this article we present the following results for the MINCCA problem: - the problem is W[1]-hard parameterized by the treedepth of the input graph, even on graphs of average degree at most 8. In particular, it is W[1]-hard parameterized by the treewidth of the input graph, which answers the main open problem of G\"oz\"upek et al. [TCS 2016]; - it is W[1]-hard on multigraphs parameterized by the tree-cutwidth of the input multigraph; - it is FPT parameterized by the star tree-cutwidth of the input graph, which is a slightly restricted version of tree-cutwidth. This result strictly generalizes the FPT result given in G\"oz\"upek et al. [TCS 2016]; - it remains NP-hard on planar graphs even when restricted to instances with at most 6 colors and 0/1 symmetric costs, or when restricted to instances with at most 8 colors, maximum degree bounded by 4, and 0/1 symmetric costs.Comment: 25 pages, 11 figure

Inductive queries for a drug designing robot scientist

It is increasingly clear that machine learning algorithms need to be integrated in an iterative scientific discovery loop, in which data is queried repeatedly by means of inductive queries and where the computer provides guidance to the experiments that are being performed. In this chapter, we summarise several key challenges in achieving this integration of machine learning and data mining algorithms in methods for the discovery of Quantitative Structure Activity Relationships (QSARs). We introduce the concept of a robot scientist, in which all steps of the discovery process are automated; we discuss the representation of molecular data such that knowledge discovery tools can analyse it, and we discuss the adaptation of machine learning and data mining algorithms to guide QSAR experiments

Planar Octilinear Drawings with One Bend Per Edge

In octilinear drawings of planar graphs, every edge is drawn as an alternating sequence of horizontal, vertical and diagonal ($45^\circ$) line-segments. In this paper, we study octilinear drawings of low edge complexity, i.e., with few bends per edge. A $k$-planar graph is a planar graph in which each vertex has degree less or equal to $k$. In particular, we prove that every 4-planar graph admits a planar octilinear drawing with at most one bend per edge on an integer grid of size $O(n^2) \times O(n)$. For 5-planar graphs, we prove that one bend per edge still suffices in order to construct planar octilinear drawings, but in super-polynomial area. However, for 6-planar graphs we give a class of graphs whose planar octilinear drawings require at least two bends per edge

Shortest Reconfiguration of Perfect Matchings via Alternating Cycles

Motivated by adjacency in perfect matching polytopes, we study the shortest reconfiguration problem of perfect matchings via alternating cycles. Namely, we want to find a shortest sequence of perfect matchings which transforms one given perfect matching to another given perfect matching such that the symmetric difference of each pair of consecutive perfect matchings is a single cycle. The problem is equivalent to the combinatorial shortest path problem in perfect matching polytopes. We prove that the problem is NP-hard even when a given graph is planar or bipartite, but it can be solved in polynomial time when the graph is outerplanar