Classification of the Gait Pattern in Polymyalgia Rheumatica Patients Using Recurrent Neural Networks

The early detection of movement disorders is essential for clinicians in many diseases, and it forms an integral part of effective treatment planning for patients. Polymyalgia rheumatica (PMR) is an autoimmune musculoskeletal disease that affects muscles around the pelvic girdle and shoulder blade. It is currently unknown how the strained hip muscles around the pelvic girdle create mobility limitations in patients. This study presents an algorithm for the classification of the hip muscle activation pattern in clinical gait analysis using recurrent neural networks (RNNs). RNNs was chosen because of its ability to capture temporal dependencies and process sequential electromyography (EMG) data in gait classification. A clinical gait assessment was conducted at KATH hospital which collected 250 gait segments from 18 PMR patients and 7 healthy control subjects. EMG signals were recorded from the vastus lateralis (VL), rectus femoris (RF), biceps femoris (BF), and semitendinosus (SE). Different optimizers were used in the RNN model to classify the hip muscle activation of the two groups to discriminate the gait pattern. Four optimizers (Adamax, Adagrad, SGD, and RMSprop) were used to evaluate the best optimizer for the RNN model. The accuracy results recorded from a cross-validation were, Adamax = 89%, Adagrad = 83%, SGD = 85%, and RMSprop = 78%. Adamax was the best performing optimizer while RMSprop was the least performing in the gait classification. An average accuracy of 84% from the four optimizers was sufficient to distinguish the gait pattern of the two groups. The findings of this study are useful in discriminating gait patterns based on hip muscle activation. This will provide essential information for the early detection of gait impairments by clinicians to make more informed a nd ti me ly decisions

Topology of Surface Electromyogram Signals: Hand Gesture Decoding on Riemannian Manifolds

Decoding gestures from the upper limb using noninvasive surface electromyogram (sEMG) signals is of keen interest for the rehabilitation of amputees, artificial supernumerary limb augmentation, gestural control of computers, and virtual/augmented realities. We show that sEMG signals recorded across an array of sensor electrodes in multiple spatial locations around the forearm evince a rich geometric pattern of global motor unit (MU) activity that can be leveraged to distinguish different hand gestures. We demonstrate a simple technique to analyze spatial patterns of muscle MU activity within a temporal window and show that distinct gestures can be classified in both supervised and unsupervised manners. Specifically, we construct symmetric positive definite (SPD) covariance matrices to represent the spatial distribution of MU activity in a time window of interest, calculated as pairwise covariance of electrical signals measured across different electrodes. This allows us to understand and manipulate multivariate sEMG timeseries on a more natural subspace -the Riemannian manifold. Furthermore, it directly addresses signal variability across individuals and sessions, which remains a major challenge in the field. sEMG signals measured at a single electrode lack contextual information such as how various anatomical and physiological factors influence the signals and how their combined effect alters the evident interaction among neighboring muscles. As we show here, analyzing spatial patterns using covariance matrices on Riemannian manifolds allows us to robustly model complex interactions across spatially distributed MUs and provides a flexible and transparent framework to quantify differences in sEMG signals across individuals. The proposed method is novel in the study of sEMG signals and its performance exceeds the current benchmarks while maintaining exceptional computational efficiency.Comment: 15 pages, 8 figures, 5 table

Myoelectric Control for Active Prostheses via Deep Neural Networks and Domain Adaptation

Recent advances in Biological Signal Processing (BSP) and Machine Learning (ML), in particular, Deep Neural Networks (DNNs), have paved the way for development of advanced Human-Machine Interface (HMI) systems for decoding human intent and controlling artificial limbs. Myoelectric control, as a subcategory of HMI sys- tems, deals with detecting, extracting, processing, and ultimately learning from Electromyogram (EMG) signals to command external devices, such as hand prostheses. In this context, hand gesture recognition/classification via Surface Electromyography (sEMG) signals has attracted a great deal of interest from many researchers. De- spite extensive progress in the field of myoelectric prosthesis, however, there are still limitations that should be addressed to achieve a more intuitive upper limb pros- thesis. Through this Ph.D. thesis, first, we perform a literature review on recent research works on pattern classification approaches for myoelectric control prosthesis to identify challenges and potential opportunities for improvement. Then, we aim to enhance the accuracy of myoelectric systems, which can be used for realizing an accu- rate and efficient HMI for myocontrol of neurorobotic systems. Beside improving the accuracy, decreasing the number of parameters in DNNs plays an important role in a Hand Gesture Recognition (HGR) system. More specifically, a key factor to achieve a more intuitive upper limb prosthesis is the feasibility of embedding DNN-based models into prostheses controllers. On the other hand, transformers are considered to be powerful DNN models that have revolutionized the Natural Language Processing (NLP) field and showed great potentials to dramatically improve different computer vision tasks. Therefore, we propose a Transformer-based neural network architecture to classify and recognize upper-limb hand gestures. Finally, another goal of this thesis is to design a modern DNN-based gesture detection model that relies on minimal training data while providing high accuracy. Although DNNs have shown superior accuracy compared to conventional methods when large amounts of data are available for training, their performance substantially decreases when data are limited. Collecting large datasets for training may be feasible in research laboratories, but it is not a practical approach for real-life applications. We propose to solve this problem, by designing a framework which utilizes a combination of temporal convolutions and attention mechanisms

Multimodaalinen käyttöliittymä interaktiivista yhteistyötä varten nelijalkaisten robottien kanssa

A variety of approaches for hand gesture recognition have been proposed, where most interest has recently been directed towards different deep learning methods. The modalities, on which these approaches are based, most commonly range from different imaging sensors to inertial measurement units (IMU) and electromyography (EMG) sensors. EMG and IMUs allow detection of gestures without being affected by the line of sight or lighting conditions. The detection algorithms are fairly well established, but their application to real world use cases is limited, apart from prostheses and exoskeletons. In this thesis, a multimodal interface for human robot interaction (HRI) is developed for quadruped robots. The interface is based on a combination of two detection algorithms; one for detecting gestures based on surface electromyography (sEMG) and IMU signals, and the other for detecting the operator using visible light and depth cameras. Multiple architectures for gesture detection are compared, where the best regression performance with offline multi-user data was achieved by a hybrid of a convolutional neural network (CNN) and a long short-term memory (LSTM), with a mean squared error (MSE) of 4.7 · 10−3 in the normalised gestures. A person-following behaviour is implemented for a quadruped robot, which is controlled using the predefined gestures. The complete interface is evaluated online by one expert user two days after recording the last samples of the training data. The gesture detection system achieved an F-score of 0.95 for the gestures alone, and 0.90, when unrecognised attempts due to other technological aspects, such as disturbances in Bluetooth data transmission, are included. The system to reached online performance levels comparable to those reported for offline sessions and online sessions with real-time visual feedback. While the current interface was successfully deployed to the robot, further advances should be aimed at improving inter-subject performance and wireless communication reliability between the devices.Käden eleiden tunnistamiseksi on ehdotettu useita vaihtoehtoisia ratkaisuja, mutta tällä hetkellä tutkimus- ja kehitystyö on pääasiassa keskittynyt erilaisiin syvän oppimisen menetelmiin. Hyödynnetyt teknologiat vaihtelevat useimmiten kuvantavista antureista inertiamittausyksiköihin (inertial measurement unit, IMU) ja lihassähkökäyrää (electromyography, EMG) mittaaviin antureihin. EMG ja IMU:t mahdollistavat eleiden tunnistuksen riippumatta näköyhteydestä tai valaistusolosuhteista. Eleiden tunnistukseen käytettävät menetelmät ovat jo melko vakiintuneita, mutta niiden käyttökohteet ovat rajoittuneet lähinnä proteeseihin ja ulkoisiin tukirankoihin. Tässä opinnäytetyössä kehitettiin useaa modaliteettia hyödyntävä käyttöliittymä ihmisen ja robotin vuorovaikutusta varten. Käyttöliittymä perustuu kahden menetelmän yhdistelmään, joista ensimmäinen vastaa eleiden tunnistuksesta pohjautuen ihon pinnalta mitattavaan EMG:hen ja IMU-signaaleihin, ja toinen käyttäjän tunnistuksesta näkyvän valon- ja syvyyskameroiden perusteella. Työssä vertaillaan useita eleiden tunnistuksen soveltuvia arkkitehtuureja, joista parhaan tuloksen usean käyttäjän opetusaineistolla saavutti konvoluutineuroverkon (convolutional neural network, CNN) ja pitkäkestoisen lyhytkestomuistin (long short-term memory, LSTM) yhdistelmäarkkitehtuuri. Normalisoitujen eleiden regression keskimääräinen neliöllinen virhe (mean squared error, MSE) oli tällä arkkitehtuurilla 4,7·10−3. Eleitä hyödynnettiin robotille toteutetun henkilön seuraamistehtävän ohjaamisessa. Lopullinen käyttöliittymä arvioitiin yhdellä kokeneella koehenkilöllä kaksi päivää viimeisten eleiden mittaamisen jälkeen. Tällöin eleiden tunnistusjärjestelmä saavutti F-testiarvon 0,95, kun vain eleiden tunnistuksen kyvykkyys huomioitiin. Arvioitaessa koko järjestelmän toimivuutta saavutettiin F-testiarvo 0,90, jossa muun muassa Bluetooth-pohjainen tiedonsiirto heikensi tuloksia. Suoraan robottiin yhteydessä ollessaan, järjestelmän saavuttama eleiden tunnistuskyky vastasi laboratorioissa suoritettujen kokeiden suorituskykyä. Vaikka järjestelmän toiminta vahvistettiin onnistuneesti, tulee tutkimuksen jatkossa keskittyä etenkin ihmisten välisen yleistymisen parantamiseen, sekä langattoman tiedonsiirron ongelmien korjaamiseen

On the Utility of Representation Learning Algorithms for Myoelectric Interfacing

Electrical activity produced by muscles during voluntary movement is a reflection of the firing patterns of relevant motor neurons and, by extension, the latent motor intent driving the movement. Once transduced via electromyography (EMG) and converted into digital form, this activity can be processed to provide an estimate of the original motor intent and is as such a feasible basis for non-invasive efferent neural interfacing. EMG-based motor intent decoding has so far received the most attention in the field of upper-limb prosthetics, where alternative means of interfacing are scarce and the utility of better control apparent. Whereas myoelectric prostheses have been available since the 1960s, available EMG control interfaces still lag behind the mechanical capabilities of the artificial limbs they are intended to steer—a gap at least partially due to limitations in current methods for translating EMG into appropriate motion commands. As the relationship between EMG signals and concurrent effector kinematics is highly non-linear and apparently stochastic, finding ways to accurately extract and combine relevant information from across electrode sites is still an active area of inquiry.This dissertation comprises an introduction and eight papers that explore issues afflicting the status quo of myoelectric decoding and possible solutions, all related through their use of learning algorithms and deep Artificial Neural Network (ANN) models. Paper I presents a Convolutional Neural Network (CNN) for multi-label movement decoding of high-density surface EMG (HD-sEMG) signals. Inspired by the successful use of CNNs in Paper I and the work of others, Paper II presents a method for automatic design of CNN architectures for use in myocontrol. Paper III introduces an ANN architecture with an appertaining training framework from which simultaneous and proportional control emerges. Paper Iv introduce a dataset of HD-sEMG signals for use with learning algorithms. Paper v applies a Recurrent Neural Network (RNN) model to decode finger forces from intramuscular EMG. Paper vI introduces a Transformer model for myoelectric interfacing that do not need additional training data to function with previously unseen users. Paper vII compares the performance of a Long Short-Term Memory (LSTM) network to that of classical pattern recognition algorithms. Lastly, paper vIII describes a framework for synthesizing EMG from multi-articulate gestures intended to reduce training burden

Human behavior understanding for worker-centered intelligent manufacturing

“In a worker-centered intelligent manufacturing system, sensing and understanding of the worker’s behavior are the primary tasks, which are essential for automatic performance evaluation & optimization, intelligent training & assistance, and human-robot collaboration. In this study, a worker-centered training & assistant system is proposed for intelligent manufacturing, which is featured with self-awareness and active-guidance. To understand the hand behavior, a method is proposed for complex hand gesture recognition using Convolutional Neural Networks (CNN) with multiview augmentation and inference fusion, from depth images captured by Microsoft Kinect. To sense and understand the worker in a more comprehensive way, a multi-modal approach is proposed for worker activity recognition using Inertial Measurement Unit (IMU) signals obtained from a Myo armband and videos from a visual camera. To automatically learn the importance of different sensors, a novel attention-based approach is proposed to human activity recognition using multiple IMU sensors worn at different body locations. To deploy the developed algorithms to the factory floor, a real-time assembly operation recognition system is proposed with fog computing and transfer learning. The proposed worker-centered training & assistant system has been validated and demonstrated the feasibility and great potential for applying to the manufacturing industry for frontline workers. Our developed approaches have been evaluated: 1) the multi-view approach outperforms the state-of-the-arts on two public benchmark datasets, 2) the multi-modal approach achieves an accuracy of 97% on a worker activity dataset including 6 activities and achieves the best performance on a public dataset, 3) the attention-based method outperforms the state-of-the-art methods on five publicly available datasets, and 4) the developed transfer learning model achieves a real-time recognition accuracy of 95% on a dataset including 10 worker operations”--Abstract, page iv

Embedded machine learning using microcontrollers in wearable and ambulatory systems for health and care applications: a review

The use of machine learning in medical and assistive applications is receiving significant attention thanks to the unique potential it offers to solve complex healthcare problems for which no other solutions had been found. Particularly promising in this field is the combination of machine learning with novel wearable devices. Machine learning models, however, suffer from being computationally demanding, which typically has resulted on the acquired data having to be transmitted to remote cloud servers for inference. This is not ideal from the system’s requirements point of view. Recently, efforts to replace the cloud servers with an alternative inference device closer to the sensing platform, has given rise to a new area of research Tiny Machine Learning (TinyML). In this work, we investigate the different challenges and specifications trade-offs associated to existing hardware options, as well as recently developed software tools, when trying to use microcontroller units (MCUs) as inference devices for health and care applications. The paper also reviews existing wearable systems incorporating MCUs for monitoring, and management, in the context of different health and care intended uses. Overall, this work addresses the gap in literature targeting the use of MCUs as edge inference devices for healthcare wearables. Thus, can be used as a kick-start for embedding machine learning models on MCUs, focusing on healthcare wearables