Wireless tools for neuromodulation

Epilepsy is a spectrum of diseases characterized by recurrent seizures. It is estimated that 50 million individuals worldwide are affected and 30% of cases are medically refractory or drug resistant. Vagus nerve stimulation (VNS) and deep brain stimulation (DBS) are the only FDA approved device based therapies. Neither therapy offers complete seizure freedom in a majority of users. Novel methodologies are needed to better understand mechanisms and chronic nature of epilepsy. Most tools for neuromodulation in rodents are tethered. The few wireless devices use batteries or are inductively powered. The tether restricts movement, limits behavioral tests, and increases the risk of infection. Batteries are large and heavy with a limited lifetime. Inductive powering suffers from rapid efficiency drops due to alignment mismatches and increased distances. Miniature wireless tools that offer behavioral freedom, data acquisition, and stimulation are needed. This dissertation presents a platform of electrical, optical and radiofrequency (RF) technologies for device based neuromodulation. The platform can be configured with features including: two channels differential recording, one channel electrical stimulation, and one channel optical stimulation. Typical device operation consumes less than 4 mW. The analog front end has a bandwidth of 0.7 Hz - 1 kHz and a gain of 60 dB, and the constant current driver provides biphasic electrical stimulation. For use with optogenetics, the deep brain optical stimulation module provides 27 mW/mm2 of blue light (473 nm) with 21.01 mA. Pairing of stimulating and recording technologies allows closed-loop operation. A wireless powering cage is designed using the resonantly coupled filter energy transfer (RCFET) methodology. RF energy is coupled through magnetic resonance. The cage has a PTE ranging from 1.8-6.28% for a volume of 11 x 11 x 11 in3. This is sufficient to chronically house subjects. The technologies are validated through various in vivo preparations. The tools are designed to study epilepsy, SUDEP, and urinary incontinence but can be configured for other studies. The broad application of these technologies can enable the scientific community to better study chronic diseases and closed-loop therapies

Ultra Wideband

Ultra wideband (UWB) has advanced and merged as a technology, and many more people are aware of the potential for this exciting technology. The current UWB field is changing rapidly with new techniques and ideas where several issues are involved in developing the systems. Among UWB system design, the UWB RF transceiver and UWB antenna are the key components. Recently, a considerable amount of researches has been devoted to the development of the UWB RF transceiver and antenna for its enabling high data transmission rates and low power consumption. Our book attempts to present current and emerging trends in-research and development of UWB systems as well as future expectations

USV charging based on WPT system

With the increasing demand of water and underwater exploration, more and more electric unmanned surface vehicles (USV) are put into use in recent years. However, because of the present battery technology limits, these devices require to be recharged frequently that is a challenging problem taking into account the complex water environment where these equipments are acting. To improve safety and convenience of USV charging a wireless power transfer (WPT) system is proposed in this dissertation. In this case, the boat can be controlled to go to the charging facilities. During charging by the implemented WPT system, the state of charging can be remotely monitored by host computer. The moving control is based on embedded system. The relative position between transmitting coil and receiving coil is supposed to be sensed by magnetic sensor, since the relative position has great impact on transmission efficiency. The remote monitoring software was implemented in the host computer and was developed in LABVIEW. A graphical user interface was developed to control the boat moving and collect the data from the WPT and the boat sensors. The effectiveness of the proposed system was tested for instance in the laboratory environment and in-field tests are also planned in the near future.Com a crescente procura da exploração em ambientes aquáticos e subaquáticos , os veículos elétricos de superfície não tripulados ("electric unmanned surface vehicle" -USV) têm sido cada vez mais utilizados nestes últimos anos. No entanto, devido aos limites atuais relacionados com a tecnologia utilizada nas baterias, os dispositivos precisam de ser recarregados com frequência para poderem operar num ambiente aquático complexo. Para melhorar a segurança e a conveniência do carregamento da bateria de um USV, um sistema para recarregamento da bateria de um barco não tripulado através de transferência de energia sem fios("wireless power transfer" - WPT) é proposto nesta dissertação. Neste caso de estudo, o barco tem a capacidade de ser controlado para chegar a um ponto de recarregamento da bateria, que se encontra fixado por uma doca mecânica. Enquanto o sistema WPT érecarregado, os dados associados ao processo de recarregamento da bateria podem ser monitorizados por um computador host. O controlo da movimentação do barco é baseado num sistema embebido. A posição relativa entre a bobina transmissora e a bobina receptora deve ser detectada pelo sensor magnético, uma vez que a posição relativa tem um grande impacto na eficiência da transmissão. Em termos do computador host, foi utilizado o software LABVIEW para programar a interface que permite controlar o movimento do barco e recolher os dados. Finalmente, a eficácia do sistema proposto foi experimentada e testada num ambiente de laboratório

Coupled resonator based wireless power transfer for bioelectronics

Implantable and wearable bioelectronics provide the ability to monitor and modulate physiological processes. They represent a promising set of technologies that can provide new treatment for patients or new tools for scientific discovery, such as in long-term studies involving small animals. As these technologies advance, two trends are clear, miniaturization and increased sophistication i.e. multiple channels, wireless bi-directional communication, and responsiveness (closed-loop devices). One primary challenge in realizing miniaturized and sophisticated bioelectronics is powering. Integration and development of wireless power transfer (WPT) technology, however, can overcome this challenge. In this dissertation, I propose the use of coupled resonator WPT for bioelectronics and present a new generalized analysis and optimization methodology, derived from complex microwave bandpass filter synthesis, for maximizing and controlling coupled resonator based WPT performance. This newly developed set of analysis and optimization methods enables system miniaturization while simultaneously achieving the necessary performance to safely power sophisticated bioelectronics. As an application example, a novel coil to coil based coupled resonator arrangement to wirelessly operate eight surface electromyography sensing devices wrapped circumferentially around an able-bodied arm is developed and demonstrated. In addition to standard coil to coil based systems, this dissertation also presents a new form of coupled resonator WPT system built of a large hollow metallic cavity resonator. By leveraging the analysis and optimization methods developed here, I present a new cavity resonator WPT system for long-term experiments involving small rodents for the first time. The cavity resonator based WPT arena exhibits a volume of 60.96 x 60.96 x 30.0 cm3. In comparison to prior state of the art, this cavity resonator system enables nearly continuous wireless operation of a miniature sophisticated device implanted in a freely behaving rodent within the largest space. Finally, I present preliminary work, providing the foundation for future studies, to demonstrate the feasibility of treating segments of the human body as a dielectric waveguide resonator. This creates another form of a coupled resonator system. Preliminary experiments demonstrated optimized coupled resonator wireless energy transfer into human tissue. The WPT performance achieved to an ultra-miniature sized receive coil (2 mm diameter) is presented. Indeed, optimized coupled resonator systems, broadened to include cavity resonator structures and human formed dielectric resonators, can enable the effective use of coupled resonator based WPT technology to power miniaturized and sophisticated bioelectronics

Journal of Telecommunications and Information Technology, 2019, nr 1

kwartalni

Journal of Telecommunications and Information Technology, 2009, nr 2

kwartalni

A Novel Power-Efficient Wireless Multi-channel Recording System for the Telemonitoring of Electroencephalography (EEG)

This research introduces the development of a novel EEG recording system that is modular, batteryless, and wireless (untethered) with the supporting theoretical foundation in wireless communications and related design elements and circuitry. Its modular construct overcomes the EEG scaling problem and makes it easier for reconfiguring the hardware design in terms of the number and placement of electrodes and type of standard EEG system contemplated for use. In this development, portability, lightweight, and applicability to other clinical applications that rely on EEG data are sought. Due to printer tolerance, the 3D printed cap consists of 61 electrode placements. This recording capacity can however extend from 21 (as in the international 10-20 systems) up to 61 EEG channels at sample rates ranging from 250 to 1000 Hz and the transfer of the raw EEG signal using a standard allocated frequency as a data carrier. The main objectives of this dissertation are to (1) eliminate the need for heavy mounted batteries, (2) overcome the requirement for bulky power systems, and (3) avoid the use of data cables to untether the EEG system from the subject for a more practical and less restrictive setting. Unpredictability and temporal variations of the EEG input make developing a battery-free and cable-free EEG reading device challenging. Professional high-quality and high-resolution analog front ends are required to capture non-stationary EEG signals at microvolt levels. The primary components of the proposed setup are the wireless power transmission unit, which consists of a power amplifier, highly efficient resonant-inductive link, rectification, regulation, and power management units, as well as the analog front end, which consists of an analog to digital converter, pre-amplification unit, filtering unit, host microprocessor, and the wireless communication unit. These must all be compatible with the rest of the system and must use the least amount of power possible while minimizing the presence of noise and the attenuation of the recorded signal A highly efficient resonant-inductive coupling link is developed to decrease power transmission dissipation. Magnetized materials were utilized to steer electromagnetic flux and decrease route and medium loss while transmitting the required energy with low dissipation. Signal pre-amplification is handled by the front-end active electrodes. Standard bio-amplifier design approaches are combined to accomplish this purpose, and a thorough investigation of the optimum ADC, microcontroller, and transceiver units has been carried out. We can minimize overall system weight and power consumption by employing battery-less and cable-free EEG readout system designs, consequently giving patients more comfort and freedom of movement. Similarly, the solutions are designed to match the performance of medical-grade equipment. The captured electrical impulses using the proposed setup can be stored for various uses, including classification, prediction, 3D source localization, and for monitoring and diagnosing different brain disorders. All the proposed designs and supporting mathematical derivations were validated through empirical and software-simulated experiments. Many of the proposed designs, including the 3D head cap, the wireless power transmission unit, and the pre-amplification unit, are already fabricated, and the schematic circuits and simulation results were based on Spice, Altium, and high-frequency structure simulator (HFSS) software. The fully integrated head cap to be fabricated would require embedding the active electrodes into the 3D headset and applying current technological advances to miniaturize some of the design elements developed in this dissertation

Distributed synchronization algorithms for wireless sensor networks

The ability to distribute time and frequency among a large population of interacting agents is of interest for diverse disciplines, inasmuch as it enables to carry out complex cooperative tasks. In a wireless sensor network (WSN), time/frequency synchronization allows the implementation of distributed signal processing and coding techniques, and the realization of coordinated access to the shared wireless medium. Large multi-hop WSN\u27s constitute a new regime for network synchronization, as they call for the development of scalable, fully distributed synchronization algorithms. While most of previous research focused on synchronization at the application layer, this thesis considers synchronization at the lowest layers of the communication protocol stack of a WSN, namely the physical and the medium access control (MAC) layer. At the physical layer, the focus is on the compensation of carrier frequency offsets (CFO), while time synchronization is studied for application at the MAC layer. In both cases, the problem of realizing network-wide synchronization is approached by employing distributed clock control algorithms based on the classical concept of coupled phase and frequency locked loops (PLL and FLL). The analysis takes into account communication, signaling and energy consumption constraints arising in the novel context of multi-hop WSN\u27s. In particular, the robustness of the algorithms is checked against packet collision events, infrequent sync updates, and errors introduced by different noise sources, such as transmission delays and clock frequency instabilities. By observing that WSN\u27s allow for greater flexibility in the design of the synchronization network architecture, this work examines also the relative merits of both peer-to-peer (mutually coupled - MC) and hierarchical (master-slave - MS) architectures. With both MC and MS architectures, synchronization accuracy degrades smoothly with the network size, provided that loop parameters are conveniently chosen. In particular, MS topologies guarantee faster synchronization, but they are hindered by higher noise accumulation, while MC topologies allow for an almost uniform error distribution at the price of much slower convergence. For all the considered cases, synchronization algorithms based on adaptive PLL and FLL designs are shown to provide robust and scalable network-wide time and frequency distribution in a WSN

A Comprehensive Survey on RF Energy Harvesting: Applications and Performance Determinants

\ua9 2022 by the authors. Licensee MDPI, Basel, Switzerland.There has been an explosion in research focused on Internet of Things (IoT) devices in recent years, with a broad range of use cases in different domains ranging from industrial automation to business analytics. Being battery-powered, these small devices are expected to last for extended periods (i.e., in some instances up to tens of years) to ensure network longevity and data streams with the required temporal and spatial granularity. It becomes even more critical when IoT devices are installed within a harsh environment where battery replacement/charging is both costly and labour intensive. Recent developments in the energy harvesting paradigm have significantly contributed towards mitigating this critical energy issue by incorporating the renewable energy potentially available within any environment in which a sensor network is deployed. Radio Frequency (RF) energy harvesting is one of the promising approaches being investigated in the research community to address this challenge, conducted by harvesting energy from the incident radio waves from both ambient and dedicated radio sources. A limited number of studies are available covering the state of the art related to specific research topics in this space, but there is a gap in the consolidation of domain knowledge associated with the factors influencing the performance of RF power harvesting systems. Moreover, a number of topics and research challenges affecting the performance of RF harvesting systems are still unreported, which deserve special attention. To this end, this article starts by providing an overview of the different application domains of RF power harvesting outlining their performance requirements and summarizing the RF power harvesting techniques with their associated power densities. It then comprehensively surveys the available literature on the horizons that affect the performance of RF energy harvesting, taking into account the evaluation metrics, power propagation models, rectenna architectures, and MAC protocols for RF energy harvesting. Finally, it summarizes the available literature associated with RF powered networks and highlights the limitations, challenges, and future research directions by synthesizing the research efforts in the field of RF energy harvesting to progress research in this area

Battery-less near field communications (nfc) sensors for internet of things (iot) applications

L’ implementació de la tecnologia de comunicació de camp proper (NFC) en els telèfons intel·ligents no para de créixer degut a l’ús d’aquesta per fer pagaments, això, junt amb el fet de poder aprofitar l’energia generada pel mòbil no només per la comunicació, sinó també per transmetre energia, el baix cost dels xips NFC, i el fet de que els telèfons tinguin connectivitat amb internet, possibilita i fa molt interesant el disseny d’etiquetes sense bateria incorporant-hi sensors i poder enviar la informació al núvol, dins del creixent escenari de l’internet de les coses (IoT). La present Tesi estudia la viabilitat d’aquests sensors, analitzant la màxima distància entre lector i sensor per proveir la potència necessària, presenta tècniques per augmentar el rang d’operació, i analitza els efectes de certs materials quan aquests estan propers a les antenes. Diversos sensors han estat dissenyats i analitzats i son presentats en aquest treball. Aquests son: Una etiqueta que mesura la humitat de la terra, la temperatura i la humitat relativa de l’aire per controlar les condicions de plantes. Un sensor per detectar la humitat en bolquers, imprès en material flexible que s’adapta a la forma del bolquer. Dues aplicacions, una per estimació de pH i una altre per avaluar el grau de maduració de fruites, basats en un sensor de color. I, per últim, s’estudia la viabilitat de sensors en implants per aplicacions mèdiques, analitzant l’efecte del cos i proposant un sistema per augmentar la profunditat a la que aquests es poden llegir utilitzant un telèfon mòbil. Tots aquests sensors poden ser alimentats i llegits per qualsevol dispositiu que disposin de connexió NFC.La implementación de la tecnología de comunicaciones de campo cercano (NFC) en los teléfonos inteligentes no para de crecer debido al uso de esta para llevar a cabo pagos, esto, junto con el hecho de poder aprovechar la energía generada por el móvil no sólo para la comunicación, sino también para transmitir energía, el bajo coste de los chips NFC, i el hecho que los teléfonos tengan conectividad a internet, posibilita y hace muy interesante el diseño de etiquetas sin batería que incorporen sensores i poder enviar la información a la nube, enmarcado en el creciente escenario del internet de las cosas (IoT). La presente Tesis estudia la viabilidad de estos sensores, analizando la máxima distancia entre lector i sensor para proveer la potencia necesaria, presenta técnicas para aumentar el rango de operación, y analiza los efectos de ciertos materiales cuando estos están cerca de las antenas. Varios sensores han sido diseñados y analizados y son presentados en este trabajo. Estos son: Una etiqueta que mide la humedad de la tierra, la temperatura y la humedad relativa del aire para controlar las condiciones de plantas. Un sensor para detectar la humedad en pañales, impreso en material flexible que se adapta a la forma del pañal. Dos aplicaciones, una para estimación de pH y otra para evaluar el grado de maduración de frutas, basados en un sensor de color. Y, por último, se estudia la viabilidad de sensores en implantes para aplicaciones médicas, analizando el efecto del cuerpo y proponiendo un sistema para aumentar la profundidad a la que estos se pueden leer usando un teléfono móvil. Todos estos sensores pueden ser alimentados y leídos por cualquier dispositivo que disponga de conexión NFC.The implementation of near field communication (NFC) technology into smartphones grows rapidly due the use of this technology as a payment system. This, altogether with the fact that the energy generated by the phone can be used not only to communicate but for power transfer as well, the low-cost of the NFC chips, and the fact that the smartphones have connectivity to internet, makes possible and very interesting the design of battery-less sensing tags which information can be sent to the cloud, within the growing internet of things (IoT) scenario. This Thesis studies the feasibility of these sensors, analysing the maximum distance between reader and sensor to provide the necessary power, presents techniques to increase the range of operation, and analyses the effects of certain materials when they are near to the antennas. Several sensors have been designed and analysed and are presented in this work. These are: a tag that measures the soil moisture, the temperature and the relative humidity of the air to control the conditions of plants. A moisture sensor for diapers, printed on flexible material that adapts to the diaper shape. Two applications, one for pH estimation and another for assessing the degree of fruit ripening, based on a colour sensor. And finally, the feasibility of sensors in implants for medical applications is studied, analysing the effect of the body and proposing a system to increase the depth at which they can be read using a mobile phone. All of these sensors can be powered and read by any NFC enabled device