Topological MRI Prostate Segmentation Method

The main aim of this paper is to advance the state of the art in automated prostate segmentation using T2 weighted MR images, by introducing a hybrid topological MRI prostate segmentation method which is based on a set of pre-labeled MR atlas images. The proposed method has been experimentally tested on a set of 30 MRI T2 weighted images. For evaluation the automated segmentations of the proposed scheme have been compared with the manual segmentations, using an average Dice Similarity Coefficient (DSC). Obtained quantitative results have shown a good approximation of the segmented prostate

Adaptation and evaluation of the multiple organs OSD for T2 MRI prostate segmentation

International audienceThis paper deals with the adaptation, the tuning and the evaluation of the multiple organs Optimal Surface Detection (OSD) algorithm for the T2 MRI prostate segmentation. This algorithm is initialized by first surface approximations of the prostate (obtained after a model adjustment), the bladder (obtained automatically) and the rectum (interactive geometrical model). These three organs are then segmented together in a multiple organs OSD scheme which proposes a competition between the gray level characteristics and some topological and anatomical information of these three organs. This method has been evaluated on the MICCAI Grand Challenge: Prostate MR Image Segmentation (PROMISE) 2012 training dataset

Histopathological image analysis : a review

Over the past decade, dramatic increases in computational power and improvement in image analysis algorithms have allowed the development of powerful computer-assisted analytical approaches to radiological data. With the recent advent of whole slide digital scanners, tissue histopathology slides can now be digitized and stored in digital image form. Consequently, digitized tissue histopathology has now become amenable to the application of computerized image analysis and machine learning techniques. Analogous to the role of computer-assisted diagnosis (CAD) algorithms in medical imaging to complement the opinion of a radiologist, CAD algorithms have begun to be developed for disease detection, diagnosis, and prognosis prediction to complement the opinion of the pathologist. In this paper, we review the recent state of the art CAD technology for digitized histopathology. This paper also briefly describes the development and application of novel image analysis technology for a few specific histopathology related problems being pursued in the United States and Europe

Disjunctive normal shape and appearance priors with applications to image segmentation

The use of appearance and shape priors in image segmentation is known to improve accuracy; however, existing techniques have several drawbacks. Active shape and appearance models require landmark points and assume unimodal shape and appearance distributions. Level set based shape priors are limited to global shape similarity. In this paper, we present a novel shape and appearance priors for image segmentation based on an implicit parametric shape representation called disjunctive normal shape model (DNSM). DNSM is formed by disjunction of conjunctions of half-spaces defined by discriminants. We learn shape and appearance statistics at varying spatial scales using nonparametric density estimation. Our method can generate a rich set of shape variations by locally combining training shapes. Additionally, by studying the intensity and texture statistics around each discriminant of our shape model, we construct a local appearance probability map. Experiments carried out on both medical and natural image datasets show the potential of the proposed method