6 research outputs found

    Distance-regular graphs

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    This is a survey of distance-regular graphs. We present an introduction to distance-regular graphs for the reader who is unfamiliar with the subject, and then give an overview of some developments in the area of distance-regular graphs since the monograph 'BCN' [Brouwer, A.E., Cohen, A.M., Neumaier, A., Distance-Regular Graphs, Springer-Verlag, Berlin, 1989] was written.Comment: 156 page

    European Journal of Combinatorics Index, Volume 27

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    BACKGROUND: Diabetes is an inflammatory condition associated with iron abnormalities and increased oxidative damage. We aimed to investigate how diabetes affects the interrelationships between these pathogenic mechanisms. METHODS: Glycaemic control, serum iron, proteins involved in iron homeostasis, global antioxidant capacity and levels of antioxidants and peroxidation products were measured in 39 type 1 and 67 type 2 diabetic patients and 100 control subjects. RESULTS: Although serum iron was lower in diabetes, serum ferritin was elevated in type 2 diabetes (p = 0.02). This increase was not related to inflammation (C-reactive protein) but inversely correlated with soluble transferrin receptors (r = - 0.38, p = 0.002). Haptoglobin was higher in both type 1 and type 2 diabetes (p &lt; 0.001) and haemopexin was higher in type 2 diabetes (p &lt; 0.001). The relation between C-reactive protein and haemopexin was lost in type 2 diabetes (r = 0.15, p = 0.27 vs r = 0.63, p &lt; 0.001 in type 1 diabetes and r = 0.36, p = 0.001 in controls). Haemopexin levels were independently determined by triacylglycerol (R(2) = 0.43) and the diabetic state (R(2) = 0.13). Regarding oxidative stress status, lower antioxidant concentrations were found for retinol and uric acid in type 1 diabetes, alpha-tocopherol and ascorbate in type 2 diabetes and protein thiols in both types. These decreases were partially explained by metabolic-, inflammatory- and iron alterations. An additional independent effect of the diabetic state on the oxidative stress status could be identified (R(2) = 0.5-0.14). CONCLUSIONS: Circulating proteins, body iron stores, inflammation, oxidative stress and their interrelationships are abnormal in patients with diabetes and differ between type 1 and type 2 diabetes</p

    Bipartite Distance-Regular Graphs of Diameter Four

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    Using a method by Godsil and Roy, bipartite distance-regular graphs of diameter four can be used to construct {0,α}\{0,\alpha\}-sets, a generalization of the widely applied equiangular sets and mutually unbiased bases. In this thesis, we study the properties of these graphs. There are three main themes of the thesis. The first is the connection between bipartite distance-regular graphs of diameter four and their halved graphs, which are necessarily strongly regular. We derive formulae relating the parameters of a graph of diameter four to those of its halved graphs, and use these formulae to derive a necessary condition for the point graph of a partial geometry to be a halved graph. Using this necessary condition, we prove that several important families of strongly regular graphs cannot be halved graphs. The second theme is the algebraic properties of the graphs. We study Krein parameters as the first part of this theme. We show that bipartite-distance regular graphs of diameter four have one ``special" Krein parameter, denoted by \krein. We show that the antipodal bipartite distance-regular graphs of diameter four with \krein=0 are precisely the Hadamard graphs. In general, we show that a bipartite distance-regular graph of diameter four satisfies \krein=0 if and only if it satisfies the so-called QQ-polynomial property. In relation to halved graphs, we derive simple formulae for computing the Krein parameters of a halved graph in terms of those of the bipartite graph. As the second part of the algebraic theme, we study Terwilliger algebras. We describe all the irreducible modules of the complex space under the Terwilliger algebra of a bipartite distance-regular graph of diameter four, and prove that no irreducible module can contain two linearly independent eigenvectors of the graph with the same eigenvalue. Finally, we study constructions and bounds of {0,α}\{0,\alpha\}-sets as the third theme. We present some distance-regular graphs that provide new constructions of {0,α}\{0,\alpha\}-sets. We prove bounds for the sizes of {0,α}\{0,\alpha\}-sets of flat vectors, and characterize all the distance-regular graphs that yield {0,α}\{0,\alpha\}-sets meeting the bounds at equality. We also study bipartite covers of linear Cayley graphs, and present a geometric condition and a coding theoretic condition for such a cover to produce {0,α}\{0,\alpha\}-sets. Using simple operations on graphs, we show how new {0,α}\{0,\alpha\}-sets can be constructed from old ones

    LIPIcs, Volume 251, ITCS 2023, Complete Volume

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    LIPIcs, Volume 251, ITCS 2023, Complete Volum
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