Change is the Only Constant

Because of the nature of mine-action organizations and programs, they are often placed in post-conflict areas where humanitarian work faces several obstacles. It is important to consider possible setbacks before embarking on demining in a post-conflict country

In Datacenter Performance, The Only Constant Is Change

All computing infrastructure suffers from performance variability, be it bare-metal or virtualized. This phenomenon originates from many sources: some transient, such as noisy neighbors, and others more permanent but sudden, such as changes or wear in hardware, changes in the underlying hypervisor stack, or even undocumented interactions between the policies of the computing resource provider and the active workloads. Thus, performance measurements obtained on clouds, HPC facilities, and, more generally, datacenter environments are almost guaranteed to exhibit performance regimes that evolve over time, which leads to undesirable nonstationarities in application performance. In this paper, we present our analysis of performance of the bare-metal hardware available on the CloudLab testbed where we focus on quantifying the evolving performance regimes using changepoint detection. We describe our findings, backed by a dataset with nearly 6.9M benchmark results collected from over 1600 machines over a period of 2 years and 9 months. These findings yield a comprehensive characterization of real-world performance variability patterns in one computing facility, a methodology for studying such patterns on other infrastructures, and contribute to a better understanding of performance variability in general.Comment: To be presented at the 20th IEEE/ACM International Symposium on Cluster, Cloud and Internet Computing (CCGrid, http://cloudbus.org/ccgrid2020/) on May 11-14, 2020 in Melbourne, Victoria, Australi

Plant stem cells: The only constant thing is change

AbstractRecent studies in Arabidopsis have uncovered a negative feedback loop that couples the antagonistic functions of the WUSCHEL and CLAVATA loci to control stem cell fate in the shoot apical meristem. Abundance of the CLAVATA3 protein limits signaling through this pathway

Cover Art: “The Only Constant Is Change”

"No man ever steps in the same river twice, for it's not the same river and he's not the same man." This quote, attributed to the Greek philosopher Heraclitus, reminds me that our lives are constantly changing. Just as the waterfall constantly erodes and reshapes the surrounding rock, our environment is constantly reforming us and informing our choices. I have to thank a friend of mine for helping me realize Heraclitus was right—we should respond to the gentle nudges our lives offer, just as rock gives way to a stream

The treatment of mitral valve disease—the only thing constant is change

The mitral valve is without doubt the part of the human body that is most under pressure. For every beat of the heart, the mitral valve has to open to let the blood into the most muscular chamber in the body, and then closes to withstand high systolic pressures that, during periods of exertion, can exceed over 200 mmHg

Changes And Challenges In Uncertain Times: When The Only Constant Is Change

The Forums Since 1997, the annual ACUTA Forum for Strategic Leadership in Information Communications Technology has provided a unique for campus leaders to exchange ideas and discuss issues relevant to the use technology in meeting the goals of higher education. Held in conjunction with ACUTA\u27s Annual Conference and Exhibition, this forum brings together men and women of vision, foresight, and authority to discuss strategic directions for the campus of the future. Goals To provide a venue for the examination of issues and challenges facing the higher education community as we grapple with planning, financing, and implementing technology on our campuses. To establish a forum in which senior university leaders with responsibility for information communicates technology can meet with their peers, share their collective expertise, and come away with solutions that will meet their institutions\u27 needs

Change Is Constant in Estate Planning: Reflections of an ACTEC Law Journal Editor

Change is the only constant in the life of a trusts and estates professional. The law changes; the needs of clients change; the methods for achieving certain results change; technology and modes of communication change. So, too, it can be said that change is the only constant running through more than forty years of our organization\u27s flagship publication