Preparing young people with complex needs and their families for transition to adult services

© RCN Publishing Company Limited 2018Improving survival rates for children and young people with complex health needs requires a robust system for transition to adult services. Effective planning is essential to ensure a smooth transition process that is in the best interests of the young person and their family. This article discusses the needs and requirements for planned and purposeful transition processes to support young people with complex healthcare needs and their families. It considers the preparation of adult services, the team, the young person and their parents in line with an integrated approach and the nurse’s role. Recommendations for practice include the necessity for an integrated approach to ensure optimum outcomes and ascertaining the potential value of a nurse-led service in delivering the transition process. A carefully tailored planning strategy should be developed to prepare and support young people with complex health needs through transition

Modular converter system for low-cost off-grid energy storage using second life Li-ion batteries

Lithium ion batteries are promising for small off- grid energy storage applications in developing countries because of their high energy density and long life. However, costs are prohibitive. Instead, we consider 'used' Li-ion batteries for this application, finding experimentally that many discarded laptop cells, for example, still have good capacity and cycle life. In order to make safe and optimal use of such cells, we present a modular power management system using a separate power converter for every cell. This novel approach allows individual batteries to be used to their full capacity. The power converters operate in voltage droop control mode to provide easy charge balancing and implement a battery management system to estimate the capacity of each cell, as we demonstrate experimentally.Comment: Presented at IEEE GHTC Oct 10-14, 2014, Silicon Valle

Standards-based wireless sensor networks for power system condition monitoring

This paper assesses the industrial needs motivating interest in wireless monito ring within the power industry, and reviews applications of WSN technology for substation condition monitoring (Section 2). A key contribution is the identification of a set of technical requirements for substation - based WSNs, focused around security requi rements, robustness to RF noise, and other utility - specific concerns (Section 3). Section 4 comprehensively assesses the suitability of various IWSN protocols for substation environments, using these requirements. A case study implementation of one standar d, ISA100.11a, is reported in Section 5, along with deployment experience. The paper concludes by describing future research challenges for WSN protocols which are specific to this domain

The active microbial community more accurately reflects the anaerobic digestion process: 16S rRNA (gene) sequencing as a predictive tool

Background: Amplicon sequencing methods targeting the 16S rRNA gene have been used extensively to investigate microbial community composition and dynamics in anaerobic digestion. These methods successfully characterize amplicons but do not distinguish micro-organisms that are actually responsible for the process. In this research, the archaeal and bacterial community of 48 full-scale anaerobic digestion plants were evaluated on DNA (total community) and RNA (active community) level via 16S rRNA (gene) amplicon sequencing. Results: A significantly higher diversity on DNA compared with the RNA level was observed for archaea, but not for bacteria. Beta diversity analysis showed a significant difference in community composition between the DNA and RNA of both bacteria and archaea. This related with 25.5 and 42.3% of total OTUs for bacteria and archaea, respectively, that showed a significant difference in their DNA and RNA profiles. Similar operational parameters affected the bacterial and archaeal community, yet the differentiating effect between DNA and RNA was much stronger for archaea. Co-occurrence networks and functional prediction profiling confirmed the clear differentiation between DNA and RNA profiles. Conclusions: In conclusion, a clear difference in active (RNA) and total (DNA) community profiles was observed, implying the need for a combined approach to estimate community stability in anaerobic digestion

Integration of multi-sensorial effects in synchronised immersive hybrid TV scenarios

[EN] Traditionally, TV media content has exclusively involved 2D or 3D audiovisual streams consumed by using a simple TV device. However, in order to generate more immersive media consumption experiences, other new types of content (e.g., omnidirectional video), consumption devices (e.g., Head Mounted Displays or HMD) and solutions to stimulate other senses beyond the traditional ones of sight and hearing, can be used. Multi-sensorial media content (a.k.a. mulsemedia) facilitates additional sensory effects that stimulate other senses during the media consumption, with the aim of providing the consumers with a more immersive and realistic experience. They provide the users with a greater degree of realism and immersion, but can also provide greater social integration (e.g., people with AV deficiencies or attention span problems) and even contribute to creating better educational programs (e.g., for learning through the senses in educational content or scientific divulgation). Examples of sensory effects that can be used are olfactory effects (scents), tactile effects (e.g., vibration, wind or pressure effects), and ambient effects (e.g., temperature or lighting). In this paper, a solution for providing multi-sensorial and immersive hybrid (broadcast/broadband) TV content consumption experiences, including omnidirectional video and sensory effects, is presented. It has been designed, implemented, and subjectively evaluated (by 32 participants) in an end-to-end platform for hybrid content generation, delivery and synchronised consumption. The satisfactory results which were obtained regarding the perception of fine synchronisation between sensory effects and multimedia content, and regarding the users' perceived QoE, are summarised and discussed.This work was supported in part by the "Vicerrectorado de Investigacion de la Universitat Politecnica de Valencia'' under Project PAID-11-21 and Project PAID-12-21.Marfil, D.; Boronat, F.; González-Salinas, J.; Sapena Piera, A. (2022). Integration of multi-sensorial effects in synchronised immersive hybrid TV scenarios. IEEE Access. 10:79071-79089. https://doi.org/10.1109/ACCESS.2022.319417079071790891

Inhibition of salt inducible kinases reduces rhythmic HIV-1 replication and reactivation from latency

Human immunodeficiency virus type 1 (HIV-1) causes a major burden on global health, and eradication of latent virus infection is one of the biggest challenges in the field. The circadian clock is an endogenous timing system that oscillates with a ~24 h period regulating multiple physiological processes and cellular functions, and we recently reported that the cell intrinsic clock regulates rhythmic HIV-1 replication. Salt inducible kinases (SIK) contribute to circadian regulatory networks, however, there is limited evidence for SIKs regulating HIV-1 infection. Here, we show that pharmacological inhibition of SIKs perturbed the cellular clock and reduced rhythmic HIV-1 replication in circadian synchronised cells. Further, SIK inhibitors or genetic silencing of Sik expression inhibited viral replication in primary cells and in a latency model, respectively. Overall, this study demonstrates a role for salt inducible kinases in regulating HIV-1 replication and latency reactivation, which can provide innovative routes to better understand and target latent HIV-1 infection

Towards Sustainable Development in Road Safety: Assessing Public Awareness on Basic Road Traffic Practices in Batu Pahat, Johor

Road accident contributes to high fatality rate around the world and being the 8th leading cause of death of all ages worldwide. Thus, road safety is essential for ensuring the safety and security of individuals of all ages, as well as reducing the number of traffic accidents and injuries as a one way to achieve Sustainable Development Goals 2030. This study aims to assess the level of road safety awareness in terms of basic road traffic practices among public who use Jalan Kluang Federal Route 50 (FT050). The level of knowledge on basic road traffic practices, the level of perceived real practice on basic road traffic practices, and the relationship between their level of knowledge and perceived real practice on basic road traffic practices were investigated. A survey method via questionnaire was distributed randomly to 200 respondents who are adults aged 18 and above and who live around Batu Pahat areas using Google Form online platform. Relevant statistical methods via Statistical Package for the Social Science Software version 26.0 (SPSS) such as descriptive, Mean Score Method, Correlation and Regression analyses were used to analyse the data.  It is found that the level of knowledge on basic road traffic practices among public is high.  Meanwhile, the level of perceived real practice on basic road traffic practices among public is low. Regression analysis results show that the awareness on knowledge of basic road traffic practices variable (β = 0.624, t = 11.229, p < 0.05) demonstrate a statistically significant relationship with perceived real practices, indicating that, the better an individual’s awareness on knowledge of basic road traffic practices (e.g. importance of safety belt, safety helmet, child restraint system (CRS) and speeding) the better the individual to actually apply the basic road traffic practices (e.g. the use of seat belt, safety helmet, CRS and speeding)

Energy-aware Approaches for Energy Harvesting Powered Wireless Sensor Systems

Energy harvesting (EH) powered wireless sensor systems (WSSs) are gaining increasing popularity since they enable the system to be self-powering, long-lasting, almost maintenance-free, and environmentally friendly. However, the mismatch between energy generated by harvesters and energy demanded by WSS to perform the required tasks is always a bottleneck as the ambient environmental energy is limited, and the WSS is power hunger. Therefore, the thesis has proposed, designed, implemented, and tested the energy-aware approaches for wireless sensor motes (WSMs) and wireless sensor networks (WSNs), including hardware energy-aware interface (EAI), software EAI, sensing EAI and network energy-aware approaches to address this mismatch. The main contributions of this thesis to the research community are designing the energy-aware approaches for EH Powered WSMs and WSNs which enables a >30 times reduction in sleep power consumption of WSNs for successful EH powering WSNs without a start-up issue in the condition of mismatch between the energy generated by harvesters and energy demanded by WSSs in both mote and network systems. For EH powered WSM systems, the energy-aware approaches have (1) enabled the harvested energy to be accumulated in energy storage devices to deal with the mismatch for the operation of the WSMs without the start-up issue, (2) enabled a commercial available WSMs with a reduced sleep current from 28.3 μA to 0.95 μA for the developed WSM, (3) thus enabled the WSM operations for a long active time of about 1.15 s in every 7.79 s to sample and transmit a large number of data (e.g., 388 bytes), rather than a few ten milliseconds and a few bytes. For EH powered WSN systems, on top of energy-aware approached for EH powered WSM, the network energy-aware approaches have presented additional capabilities for network joining process for energy-saving and enabled EH powered WSNs. Once the EH powered WSM with the network energy-aware approach is powered up and began the network joining process, energy, as an example of 48.23 mJ for a tested case, has been saved in the case of the attempt to join the network unsuccessfully. Once the EH-WSM has joined the network successfully, the smart programme applications that incorporate the software EAI, sensing EAI and hardware EAI allow the EH powered WSM to achieve (4) asynchronous operation or (5) synchronised operation based on the energy available after the WSM has joined the network.Through designs, implementations, and analyses, it has been shown that the developed energy-aware approaches have provided an enabled capability for EH successfully powering WSS technologies in the condition of energy mismatch, and it has the potential to be used for wide industrial applications

Towards Sustainable Development in Road Safety: Assessing Public Awareness on Basic Road Traffic Practices in Batu Pahat, Johor

Road accident contributes to high fatality rate around the world and being the 8th leading cause of death of all ages worldwide. Thus, road safety is essential for ensuring the safety and security of individuals of all ages, as well as reducing the number of traffic accidents and injuries as a one way to achieve Sustainable Development Goals 2030. This study aims to assess the level of road safety awareness in terms of basic road traffic practices among public who use Jalan Kluang Federal Route 50 (FT050). The level of knowledge on basic road traffic practices, the level of perceived real practice on basic road traffic practices, and the relationship between their level of knowledge and perceived real practice on basic road traffic practices were investigated. A survey method via questionnaire was distributed randomly to 200 respondents who are adults aged 18 and above and who live around Batu Pahat areas using Google Form online platform. Relevant statistical methods via Statistical Package for the Social Science Software version 26.0 (SPSS) such as descriptive, Mean Score Method, Correlation and Regression analyses were used to analyse the data.  It is found that the level of knowledge on basic road traffic practices among public is high.  Meanwhile, the level of perceived real practice on basic road traffic practices among public is low. Regression analysis results show that the awareness on knowledge of basic road traffic practices variable (β = 0.624, t = 11.229, p < 0.05) demonstrate a statistically significant relationship with perceived real practices, indicating that, the better an individual’s awareness on knowledge of basic road traffic practices (e.g. importance of safety belt, safety helmet, child restraint system (CRS) and speeding) the better the individual to actually apply the basic road traffic practices (e.g. the use of seat belt, safety helmet, CRS and speeding)